CCV
MCID: CTN025
MIFTS: 24

Cutaneous Collagenous Vasculopathy (CCV)

Categories: Cardiovascular diseases, Rare diseases, Skin diseases

Aliases & Classifications for Cutaneous Collagenous Vasculopathy

MalaCards integrated aliases for Cutaneous Collagenous Vasculopathy:

Name: Cutaneous Collagenous Vasculopathy 52 58
Ccv 52 58

Characteristics:

Orphanet epidemiological data:

58
cutaneous collagenous vasculopathy
Inheritance: Not applicable; Prevalence: <1/1000000 (Worldwide); Age of onset: Adult;

Classifications:

Orphanet: 58  
Rare skin diseases


Summaries for Cutaneous Collagenous Vasculopathy

NIH Rare Diseases : 52 The following summary is from Orphanet , a European reference portal for information on rare diseases and orphan drugs. Orpha Number: 280779 Definition Cutaneous collagenous vasculopathy (CCV) is a primary microangiopathy confined to the skin, characterized by multiple and widespread telangiectasias. Epidemiology It is a rare disorder with less than 20 cases reported in the literature to date. Clinical description Most patients present in adulthood with symmetrical telangiectasias appearing on the lower extremities and later progressing to the trunk and upper extremities. Etiology The etiology is unknown but CCV is thought to be associated with collagen abnormalities in the skin microvasculature. It can be distinguished from generalized essential telangiectasia (see this term) by characteristic histopathological features that reveal the presence of thickened vascular walls in CCV. Visit the Orphanet disease page for more resources.

MalaCards based summary : Cutaneous Collagenous Vasculopathy, also known as ccv, is related to telangiectasis and telangiectasia, hereditary benign. Affiliated tissues include skin, breast and endothelial, and related phenotypes are diffuse telangiectasia and skin rash

Related Diseases for Cutaneous Collagenous Vasculopathy

Diseases related to Cutaneous Collagenous Vasculopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 22)
# Related Disease Score Top Affiliating Genes
1 telangiectasis 10.6
2 telangiectasia, hereditary benign 10.5
3 telangiectasia macularis eruptive perstans 10.2
4 hereditary hemorrhagic telangiectasia 10.1
5 purpura 10.1
6 breast cancer 9.9
7 pigmented purpuric eruption 9.9
8 varicose veins 9.9
9 ataxia-telangiectasia 9.9
10 lipoid proteinosis of urbach and wiethe 9.9
11 ataxia and polyneuropathy, adult-onset 9.9
12 exanthem 9.9
13 cutaneous t cell lymphoma 9.9
14 hypothyroidism 9.9
15 hemorrhagic disease 9.9
16 cryoglobulinemia 9.9
17 mastocytosis 9.9
18 vasculitis 9.9
19 amyloidosis 9.9
20 hypersensitivity vasculitis 9.9
21 reactive angioendotheliomatosis 9.9
22 thrombotic microangiopathy 9.9

Graphical network of the top 20 diseases related to Cutaneous Collagenous Vasculopathy:



Diseases related to Cutaneous Collagenous Vasculopathy

Symptoms & Phenotypes for Cutaneous Collagenous Vasculopathy

Human phenotypes related to Cutaneous Collagenous Vasculopathy:

58 31 (show all 10)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 diffuse telangiectasia 58 31 obligate (100%) Obligate (100%) HP:0007489
2 skin rash 58 31 hallmark (90%) Very frequent (99-80%) HP:0000988
3 erythema 58 31 hallmark (90%) Very frequent (99-80%) HP:0010783
4 macule 58 31 hallmark (90%) Very frequent (99-80%) HP:0012733
5 bruising susceptibility 58 31 hallmark (90%) Very frequent (99-80%) HP:0000978
6 petechiae 58 31 hallmark (90%) Very frequent (99-80%) HP:0000967
7 prominent superficial blood vessels 58 31 hallmark (90%) Very frequent (99-80%) HP:0007394
8 abnormality of metabolism/homeostasis 58 31 frequent (33%) Frequent (79-30%) HP:0001939
9 pruritus 58 31 occasional (7.5%) Occasional (29-5%) HP:0000989
10 vascular skin abnormality 58 Very frequent (99-80%)

Drugs & Therapeutics for Cutaneous Collagenous Vasculopathy

Search Clinical Trials , NIH Clinical Center for Cutaneous Collagenous Vasculopathy

Genetic Tests for Cutaneous Collagenous Vasculopathy

Anatomical Context for Cutaneous Collagenous Vasculopathy

MalaCards organs/tissues related to Cutaneous Collagenous Vasculopathy:

40
Skin, Breast, Endothelial

Publications for Cutaneous Collagenous Vasculopathy

Articles related to Cutaneous Collagenous Vasculopathy:

(show all 40)
# Title Authors PMID Year
1
Cutaneous collagenous vasculopathy: papular form. 61
31553863 2019
2
Cutaneous collagenous vasculopathy: Differential diagnosis of primary telangiectasia as generalized essential telangiectasia, hereditary hemorrhagic telangiectasia, and hereditary benign telangiectasia. 61
30355073 2019
3
Cutaneous collagenous vasculopathy: light and transmission electron microscopy. 61
31090827 2019
4
Cutaneous collagenous vasculopathy. 61
30893403 2019
5
Cutaneous Collagenous Vasculopathy: A Unique Case With Positive Direct Immunofluorescence Findings. 61
29135504 2019
6
Cutaneous collagenous vasculopathy induced by the vascular endothelial growth factor receptor inhibitor axitinib. 61
30229881 2018
7
Dermoscopic Features of Cutaneous Collagenous Vasculopathy: A Report of Rare Disorder. 61
30258807 2018
8
Cutaneous collagenous vasculopathy: development after coronary artery bypass surgery. 61
30142740 2018
9
A rare cause of blanching red legs: cutaneous collagenous vasculopathy. 61
29359327 2018
10
Multiple progressive annular telangiectasias: A clinicopathological variant of cutaneous collagenous vasculopathy? 61
28815656 2017
11
Cutaneous collagenous vasculopathy - remission of perivascular deposits after pulsed dye laser therapy. 61
28796419 2017
12
Cutaneous Collagenous Vasculopathy: Report of Two Cases Presenting as Disseminated Telangiectasias and Review of the Literature. 61
28609342 2017
13
Cutaneous collagenous vasculopathy: Report of first Japanese case and review of the literature. 61
26820098 2017
14
Extensive Acquired Telangiectasias: Comparison of Generalized Essential Telangiectasia and Cutaneous Collagenous Vasculopathy. 61
27663404 2017
15
Cutaneous collagenous vasculopathy: A rare cause of generalized cutaneous telangiectasia. 61
27345854 2017
16
Gemcitabine Induced Cutaneous Collagenous Vasculopathy in a Breast Cancer Patient. 61
27346284 2016
17
A rare case of cutaneous collagenous vasculopathy. 61
25872701 2016
18
Cutaneous Collagenous Vasculopathy: A Case Report and Review of the Literature. 61
26829992 2016
19
Cutaneous Collagenous Vasculopathy-Associated Benign Pigmented Purpura. 61
27784525 2016
20
Cutaneous collagenous vasculopathy: A rare case report. 61
26955587 2016
21
Cutaneous Collagenous Vasculopathy: A Rare Form of Microangiopathy Successfully Treated with a Combination of Multiplex Laser and Optimized Pulsed Light with a Review of the Literature. 61
26529258 2016
22
Cutaneous Collagenous Vasculopathy. 61
26705441 2015
23
IMAGES IN CLINICAL MEDICINE. Cutaneous Collagenous Vasculopathy. 61
26376155 2015
24
Hypothermic cutaneous collagenous vasculopathy with centrifugal spreading. 61
24684344 2015
25
Cutaneous collagenous vasculopathy: a rare cause of generalised cutaneous telangiectasia. 61
26156838 2015
26
Cutaneous collagenous vasculopathy: a new case series with clinicopathologic and ultrastructural correlation, literature review, and insight into the pathogenesis. 61
25079204 2015
27
Cutaneous collagenous vasculopathy associated with intravascular occlusive fibrin thrombi. 61
24350781 2014
28
Cutaneous collagenous vasculopathy: report of a case. 61
24450657 2014
29
Cutaneous collagenous vasculopathy. 61
23373519 2013
30
Cutaneous collagenous vasculopathy successfully treated with pulsed dye laser. 61
23067086 2012
31
Cutaneous collagenous vasculopathy: a rare cutaneous microangiopathy. 61
22804092 2012
32
[Cutaneous collagenous vasculopathy: a rare cause of generalized telangiectasia]. 61
22578343 2012
33
Cutaneous collagenous vasculopathy: description of two new cases in elderly women and review of the literature. 61
22814232 2012
34
Cutaneous collagenous vasculopathy: report of the first pediatric case. 61
21916964 2011
35
Cutaneous collagenous vasculopathy. 61
21571177 2011
36
Cutaneous collagenous vasculopathy with generalized telangiectasia in two female patients. 61
20451292 2010
37
[Cutaneous collagenous vasculopathy: a case report and review of the literature]. 61
20525488 2010
38
Cutaneous collagenous vasculopathy: ultrastructural and immunohistochemical study of a new case. 61
20000878 2010
39
Collagenous vasculopathy: a report of three cases. 61
18537865 2008
40
Cutaneous collagenous vasculopathy with generalized telangiectasia: an immunohistochemical and ultrastructural study. 61
10660131 2000

Variations for Cutaneous Collagenous Vasculopathy

Expression for Cutaneous Collagenous Vasculopathy

Search GEO for disease gene expression data for Cutaneous Collagenous Vasculopathy.

Pathways for Cutaneous Collagenous Vasculopathy

GO Terms for Cutaneous Collagenous Vasculopathy

Sources for Cutaneous Collagenous Vasculopathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
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43 MeSH
44 MESH via Orphanet
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48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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