MCID: CTN010
MIFTS: 26

Cutaneous Ganglioneuroma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Cutaneous Ganglioneuroma

MalaCards integrated aliases for Cutaneous Ganglioneuroma:

Name: Cutaneous Ganglioneuroma 12 15
Ganglioneuroma of Skin 12 72

Classifications:



External Ids:

Disease Ontology 12 DOID:2425
NCIt 50 C4481
UMLS 72 C0346063

Summaries for Cutaneous Ganglioneuroma

MalaCards based summary : Cutaneous Ganglioneuroma, also known as ganglioneuroma of skin, is related to ganglioneuroma and neurofibroma. An important gene associated with Cutaneous Ganglioneuroma is GNS (Glucosamine (N-Acetyl)-6-Sulfatase), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include skin and adipocyte, and related phenotypes are behavior/neurological and nervous system

Related Diseases for Cutaneous Ganglioneuroma

Diseases related to Cutaneous Ganglioneuroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 204)
# Related Disease Score Top Affiliating Genes
1 ganglioneuroma 30.4 SYP NCAM1 ENO2 CHGA
2 neurofibroma 30.0 SYP MITF KIT
3 multiple mucosal neuroma 10.6 NCAM1 ENO2
4 epithelioid cell melanoma 10.6 MITF ENO2
5 lung meningioma 10.6 NCAM1 ENO2
6 choriocarcinoma of ovary 10.6 NCAM1 ENO2
7 papillary transitional carcinoma 10.6 KRT20 ENO2
8 middle cerebral artery infarction 10.6 NCAM1 ENO2
9 intracranial primitive neuroectodermal tumor 10.5 ENO2 CHGA
10 somatostatinoma 10.5 ENO2 CHGA
11 epithelioid malignant peripheral nerve sheath tumor 10.5 ENO2 CHGA
12 morpheaform basal cell carcinoma 10.5 NCAM1 KRT20
13 ganglioneuroblastoma 10.5 SYP ENO2
14 lung oat cell carcinoma 10.5 ENO2 CHGA
15 carotid body cancer 10.5 SYP ENO2
16 malignant sertoli cell tumor 10.5 SYP ENO2
17 acute thyroiditis 10.5 ENO2 CHGA
18 sinonasal undifferentiated carcinoma 10.5 SYP ENO2
19 vaginal tubulovillous adenoma 10.5 KRT20 CHGA
20 vaginal adenoma 10.5 KRT20 CHGA
21 vaginal benign neoplasm 10.5 KRT20 CHGA
22 papillary tumor of the pineal region 10.5 SYP ENO2
23 pancreatic somatostatinoma 10.5 SYP ENO2
24 middle ear adenoma 10.5 SYP ENO2
25 sensory organ benign neoplasm 10.5 SYP ENO2
26 lung combined type small cell carcinoma 10.5 SYP NCAM1
27 clear cell ependymoma 10.5 SYP ENO2
28 cerebellum cancer 10.5 SYP ENO2
29 lymphoepithelioma-like carcinoma 10.5 KRT20 ENO2
30 central nervous system primitive neuroectodermal neoplasm 10.5 SYP ENO2
31 fibroepithelial basal cell carcinoma 10.5 KRT20 CHGA
32 cerebral neuroblastoma 10.5 SYP ENO2
33 astroblastoma 10.5 SYP ENO2
34 malignant teratoma 10.5 SYP ENO2
35 subependymal glioma 10.5 SYP ENO2
36 extraosseous chondrosarcoma 10.5 SYP ENO2
37 hypoganglionosis 10.5 SYP NCAM1
38 pineal gland cancer 10.5 SYP ENO2
39 gangliocytoma 10.5
40 cerebral ventricle cancer 10.5 SYP ENO2
41 benign ependymoma 10.5 SYP ENO2
42 melanotic neuroectodermal tumor 10.5 SYP ENO2
43 duodenal gastrinoma 10.4 ENO2 CHGA
44 cystadenofibroma 10.4 NCAM1 KRT20
45 pancreatic endocrine carcinoma 10.4 SYP NCAM1
46 desmoplastic small round cell tumor 10.4 SYP ENO2
47 rhabdoid cancer 10.4 SYP ENO2
48 supratentorial primitive neuroectodermal tumor 10.4 SYP NCAM1
49 mucinous ovarian cystadenoma 10.4 SYP ENO2
50 ureter small cell carcinoma 10.4 SYP CHGA

Graphical network of the top 20 diseases related to Cutaneous Ganglioneuroma:



Diseases related to Cutaneous Ganglioneuroma

Symptoms & Phenotypes for Cutaneous Ganglioneuroma

MGI Mouse Phenotypes related to Cutaneous Ganglioneuroma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.76 APP CNP ENO2 GNS KIT MITF
2 nervous system MP:0003631 9.61 APP CHGA CNP ENO2 GNS KIT
3 reproductive system MP:0005389 9.1 APP CHGA CNP KIT MITF S100A6

Drugs & Therapeutics for Cutaneous Ganglioneuroma

Search Clinical Trials , NIH Clinical Center for Cutaneous Ganglioneuroma

Genetic Tests for Cutaneous Ganglioneuroma

Anatomical Context for Cutaneous Ganglioneuroma

MalaCards organs/tissues related to Cutaneous Ganglioneuroma:

41
Skin, Adipocyte

Publications for Cutaneous Ganglioneuroma

Articles related to Cutaneous Ganglioneuroma:

(show all 16)
# Title Authors PMID Year
1
Cutaneous ganglioneuroma: A case report and discussion of the literature. 38
30632184 2019
2
Primary cutaneous ganglioneuroma: anatomico-clinical study of 4 cases with focus on Merkel cells. 38
29569258 2018
3
Ganglion cell like cells, diagnostic dilemma. 38
23919032 2013
4
Primary cutaneous ganglioneuroma of the finger mimicking verruca vulgaris: a case report. 38
22719011 2013
5
Acquired primary cutaneous ganglioneuroma with adipocytic metaplasia: "An end point of melanocytic 'maturation'?" a case report and meta-analysis with comparison to a cross-sectional study of neurotized melanocytic nevi. 38
21048488 2011
6
[Facial primary cutaneous ganglioneuroma]. 38
19364589 2009
7
Cutaneous ganglioneuroma associated with overlying hyperkeratotic epidermal changes: a report of 2 cases. 38
19033938 2008
8
Cutaneous ganglioneuroma. 38
17651174 2007
9
Primary cutaneous ganglioneuroma arising within a seborrheic keratosis: a rare association. 38
15725239 2005
10
Cutaneous ganglioneuroma within a giant congenital nevus. 38
24223002 2005
11
Primary cutaneous ganglioneuroma: a report of two cases and literature review. 38
12775986 2003
12
A case of cutaneous ganglioneuroma developing within a lesion of seborrheic keratosis. 38
12081162 2002
13
Desmoplastic cutaneous ganglioneuroma. 38
9934592 1999
14
Primary congenital cutaneous ganglioneuroma. 38
8698926 1996
15
Cutaneous ganglioneuromas: a case report and review of the literature. 38
8698321 1996
16
Cutaneous ganglion cell choristoma. Report of a case. 38
1774358 1991

Variations for Cutaneous Ganglioneuroma

Expression for Cutaneous Ganglioneuroma

Search GEO for disease gene expression data for Cutaneous Ganglioneuroma.

Pathways for Cutaneous Ganglioneuroma

Pathways related to Cutaneous Ganglioneuroma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.56 SYP NCAM1 ENO2 CNP APP

GO Terms for Cutaneous Ganglioneuroma

Cellular components related to Cutaneous Ganglioneuroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 presynaptic active zone GO:0048786 8.96 SYP APP
2 mast cell granule GO:0042629 8.62 KIT CHGA

Biological processes related to Cutaneous Ganglioneuroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 pigmentation GO:0043473 9.4 MITF KIT
2 regulation of long-term neuronal synaptic plasticity GO:0048169 9.37 SYP APP
3 axonogenesis GO:0007409 9.33 S100A6 CNP APP
4 melanocyte differentiation GO:0030318 9.32 MITF KIT
5 mast cell degranulation GO:0043303 9.26 KIT CHGA
6 mast cell chemotaxis GO:0002551 8.96 KIT CHGA
7 mast cell cytokine production GO:0032762 8.62 KIT CHGA

Sources for Cutaneous Ganglioneuroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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