MCID: CYN003
MIFTS: 24

Cyanide Poisoning

Categories: Rare diseases

Aliases & Classifications for Cyanide Poisoning

MalaCards integrated aliases for Cyanide Poisoning:

Name: Cyanide Poisoning 58

Classifications:



External Ids:

ICD10 via Orphanet 33 T65.0
Orphanet 58 ORPHA466670

Summaries for Cyanide Poisoning

MalaCards based summary : Cyanide Poisoning is related to metabolic acidosis and lactic acidosis. An important gene associated with Cyanide Poisoning is HBG2 (Hemoglobin Subunit Gamma 2). The drugs Hydrogen sulfide and Antidotes have been mentioned in the context of this disorder. Affiliated tissues include heart, brain and skin, and related phenotype is Increased shRNA abundance.

Wikipedia : 74 Cyanide poisoning is poisoning that results from exposure to a number of forms of cyanide. Early... more...

Related Diseases for Cyanide Poisoning

Graphical network of the top 20 diseases related to Cyanide Poisoning:



Diseases related to Cyanide Poisoning

Symptoms & Phenotypes for Cyanide Poisoning

GenomeRNAi Phenotypes related to Cyanide Poisoning according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance GR00327-A 8.62 HBG2 MPST

Drugs & Therapeutics for Cyanide Poisoning

Drugs for Cyanide Poisoning (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydrogen sulfide Phase 2 7783-06-4 402
2 Antidotes Phase 2
3 Protective Agents Phase 2
4 Anti-Infective Agents Phase 2
5 Chelating Agents Phase 2
6 Antitubercular Agents Phase 2
7 sodium thiosulfate Phase 2
8 Anti-Bacterial Agents Phase 2
9 Antioxidants Phase 2
10
Calcium Approved, Nutraceutical 7440-70-2 271
11 Calcium, Dietary

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Groningen Intervention Study for the Preservation of Cardiac Function With Sodium Thiosulfate After ST-segment Elevation Myocardial Infarction Recruiting NCT02899364 Phase 2 Sodium thiosulfate;Sodium chloride 0.9%
2 Subcutaneous Injection of Sodium Thiosulfate for Ectopic Calcifications or Ossifications. A Pilot Study Not yet recruiting NCT03582800 Phase 2 STS
3 European Survey: Risk of Cyanide Poisoning in Smoke Inhalation, Symptoms, Key Treatment and Outcome (RISK) Completed NCT01386788
4 Is it Possible to Treat Cyanide Poisoning With HBO? Completed NCT00399100
5 The Effect of Sodium Thiosulfate Treatment on Vascular Calcification in End Stage Renal Failure Patients Completed NCT00568399 sodium thiosulfate
6 Treatment of Ectopic Calcification / Ossification With Sodium Thiosulfate (CATSSO) Recruiting NCT03979378
7 Using an Electronic Nose to Predict Gastrointestinal Consequences of Pelvic Radiotherapy Active, not recruiting NCT02649491
8 Cyanide Poisoning in Fire Victims Withdrawn NCT00280579
9 Hydroxycobalamin and Rural Emergency Medical Services Cyanide Exposure Patients: A Cost Analysis Withdrawn NCT01656616 Cyanide antidote administration

Search NIH Clinical Center for Cyanide Poisoning

Genetic Tests for Cyanide Poisoning

Anatomical Context for Cyanide Poisoning

MalaCards organs/tissues related to Cyanide Poisoning:

40
Heart, Brain, Skin, Testes, Liver, Skeletal Muscle, Kidney

Publications for Cyanide Poisoning

Articles related to Cyanide Poisoning:

(show top 50) (show all 720)
# Title Authors PMID Year
1
Intramuscular sodium tetrathionate as an antidote in a clinically relevant swine model of acute cyanide toxicity. 61
31008657 2020
2
Vitamin B12 for the treatment of vasoplegia in cardiac surgery and liver transplantation: a narrative review of cases and potential biochemical mechanisms. 61
31346957 2019
3
Cyanide concentrations in blood and tissues of fire victims. 61
31711010 2019
4
From Fixing Photos to Fixing Cyanide Poisoning: Herschel's "Hypo" or Sodium Thiosulfate. 61
31613861 2019
5
Behavioural and physiological assessments of dimethyl trisulfide treatment for acute oral sodium cyanide poisoning. 61
30843331 2019
6
Bacterial Cheaters Evade Punishment by Cyanide. 61
31357168 2019
7
Biodegradable Therapeutic Microneedle Patch for Rapid Antihypertensive Treatment. 61
31382742 2019
8
Modest and variable efficacy of pre-exposure hydroxocobalamin and dicobalt edetate in a porcine model of acute cyanide salt poisoning. 61
31389254 2019
9
Determination of free cyano-cobinamide in swine and rabbit plasma by liquid chromatography tandem mass spectrometry. 61
31185415 2019
10
Fatality from potassium gold cyanide poisoning. 61
31350229 2019
11
Efficacy assessment of co-treated alpha-ketoglutarate and N-acetyl cysteine against the subchronic toxicity of cyanide in rats. 61
31244408 2019
12
En Route Resuscitation - Utilization of CCATT to Transport and Stabilize Critically Injured and Unstable Casualties. 61
30535030 2019
13
Outbreak of Cyanide Poisoning Caused by Consumption of Cassava Flour - Kasese District, Uganda, September 2017. 61
30946738 2019
14
A Review on Ingested Cyanide: Risks, Clinical Presentation, Diagnostics, and Treatment Challenges. 61
30539383 2019
15
Cyanide Toxicity!! Colour of Blood Says It All. 61
31097895 2019
16
Intramuscular administration of hexachloroplatinate reverses cyanide-induced metabolic derangements and counteracts severe cyanide poisoning. 61
31355359 2019
17
Rationally designed molecules for resurgence of cyanide mitigated cytochrome c oxidase activity. 61
30391853 2019
18
Chemical and Clinical Aspects of Metal-Containing Antidotes for Poisoning by Cyanide. 61
30855115 2019
19
A Case of Hydroxocobalamin-Induced False Blood Leak Alarm on Dialysis Machine. 61
31701774 2019
20
An inhalational swine model for the characterization of physiological effects and toxicological profile associated with cyanide poisoning. 61
30757927 2018
21
Characterization of a Swine (Sus scrofa) Model of Oral Potassium Cyanide Intoxication. 61
30208987 2018
22
Challenges in the diagnosis of acute cyanide poisoning. 61
29417853 2018
23
Determinants of Lactic Acidosis in Acute Cyanide Poisonings. 61
29543597 2018
24
Cyanide poisoning is a possible cause of cardiac arrest among fire victims, and empiric antidote treatment may improve outcomes. 61
29395761 2018
25
Alpha ketoglutarate nanoparticles: A potentially effective treatment for cyanide poisoning. 61
28629719 2018
26
DMTS is an effective treatment in both inhalation and injection models for cyanide poisoning using unanesthetized mice. 61
28922956 2018
27
Neuronal nitric oxide inhibition attenuates the protective effect of HBO2 during cyanide poisoning. 61
30028920 2018
28
Methylene blue counteracts cyanide cardiotoxicity: cellular mechanisms. 61
29420146 2018
29
Cyanide poisoning in Thailand before and after establishment of the National Antidote Project. 61
28871819 2018
30
Carbon Monoxide and Cyanide Poisoning in the Burned Pregnant Patient: An Indication for Hyperbaric Oxygen Therapy. 61
29461288 2018
31
Modulating Electrocatalysis on Graphene Heterostructures: Physically Impermeable Yet Electronically Transparent Electrodes. 61
29444401 2018
32
Lactate blood measurement in acute cyanide poisoning: effect of preanalytical delay and hydroxocobalamin uses as treatment. 61
29243660 2018
33
Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning. 61
29879736 2018
34
[Socioemotional disorders in children living in Konzo-affected areas, an epidemic paralytic disease associated with cyanide poisoning from food in sub-Saharan Africa]. 61
31037178 2018
35
[A case report of acute severe hydrogen cyanide poisoning]. 61
29495184 2018
36
Inhaled cyanide poisoning as a vital sign in a room fire victim. 61
29128126 2017
37
Hemolysis index to detect degree of hydroxocobalamin interference with common laboratory tests. 61
27859624 2017
38
Live reef fish displaying physiological evidence of cyanide poisoning are still traded in the EU marine aquarium industry. 61
28747697 2017
39
Sodium Nitrite and Sodium Thiosulfate Are Effective Against Acute Cyanide Poisoning When Administered by Intramuscular Injection. 61
28041825 2017
40
Methylene blue modulates functional connectivity in the human brain. 61
26961091 2017
41
High-dose hydroxocobalamin for vasoplegic syndrome causing false blood leak alarm. 61
28616214 2017
42
Oral Glycine and Sodium Thiosulfate for Lethal Cyanide Ingestion. 61
28868209 2017
43
In-vitro mercaptopyruvate sulfurtransferase species comparison in humans and common laboratory animals. 61
28412453 2017
44
Cisplatin Analogs Confer Protection against Cyanide Poisoning. 61
28416275 2017
45
Hemodialysis failure secondary to hydroxocobalamin exposure. 61
28405068 2017
46
Effectiveness of isosorbide dinitrate in cyanide poisoning as a function of the administration timing. 61
28288687 2017
47
Cyanide poisoning of a Cooper's hawk ( Accipiter cooperii). 61
28114852 2017
48
Application of 2-Aminothiazoline-4-carboxylic Acid as a Forensic Marker of Cyanide Exposure. 61
28080046 2017
49
Method development for detecting the novel cyanide antidote dimethyl trisulfide from blood and brain, and its interaction with blood. 61
28110144 2017
50
Organic Cyanide Decorated SERS Active Nanopipettes for Quantitative Detection of Hemeproteins and Fe3+ in Single Cells. 61
28193002 2017

Variations for Cyanide Poisoning

Expression for Cyanide Poisoning

Search GEO for disease gene expression data for Cyanide Poisoning.

Pathways for Cyanide Poisoning

GO Terms for Cyanide Poisoning

Sources for Cyanide Poisoning

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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