MCID: CYC002
MIFTS: 33

Cyclosporiasis

Categories: Gastrointestinal diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Cyclosporiasis

MalaCards integrated aliases for Cyclosporiasis:

Name: Cyclosporiasis 12 53 3 44 15 17 72
Cyclospora Infection 53 3
Cyclosporosis 53 59

Characteristics:

Orphanet epidemiological data:

59
cyclosporosis
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy;

Classifications:

Orphanet: 59  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:12750
ICD9CM 35 007.5
MeSH 44 D021866
NCIt 50 C128409
ICD10 33 A07.4
ICD10 via Orphanet 34 A07.3
Orphanet 59 ORPHA210
UMLS 72 C0343398

Summaries for Cyclosporiasis

CDC : 3 Cyclosporiasis is an intestinal illness caused by the microscopic parasite Cyclospora cayetanensis. People can become infected with Cyclospora by consuming food or water contaminated with the parasite. People living or traveling in countries where cyclosporiasis is endemic may be at increased risk for infection.

MalaCards based summary : Cyclosporiasis, also known as cyclospora infection, is related to diarrhea and gastroenteritis. An important gene associated with Cyclosporiasis is CD4 (CD4 Molecule), and among its related pathways/superpathways are Selenium Micronutrient Network and Glutathione metabolism. Affiliated tissues include testes and small intestine.

Disease Ontology : 12 A coccidiosis that involves infection of the intestine with the parasitic protozoan Cyclospora cayetanensis, which is transmitted by contaminated food and water. The symptoms include watery diarrhea, anorexia, weight loss, abdominal pain, nausea and vomiting, myalgias, low-grade fever, and fatigue.

Wikipedia : 75 Cyclosporiasis is a disease caused by infection with Cyclospora cayetanensis, a pathogenic protozoan... more...

Related Diseases for Cyclosporiasis

Graphical network of the top 20 diseases related to Cyclosporiasis:



Diseases related to Cyclosporiasis

Symptoms & Phenotypes for Cyclosporiasis

Drugs & Therapeutics for Cyclosporiasis

Search Clinical Trials , NIH Clinical Center for Cyclosporiasis

Cochrane evidence based reviews: cyclosporiasis

Genetic Tests for Cyclosporiasis

Anatomical Context for Cyclosporiasis

MalaCards organs/tissues related to Cyclosporiasis:

41
Testes, Small Intestine

Publications for Cyclosporiasis

Articles related to Cyclosporiasis:

(show top 50) (show all 184)
# Title Authors PMID Year
1
Genotyping genetically heterogeneous Cyclospora cayetanensis infections to complement epidemiological case linkage. 38
31148531 2019
2
Mitochondrial Junction Region as Genotyping Marker for Cyclospora cayetanensis. 38
31211668 2019
3
Human cyclosporiasis. 38
30885589 2019
4
Outbreak of cyclosporiasis in a U.S. Air Force training population, Joint Base San Antonio-Lackland, TX, 2018. 38
31237763 2019
5
Cyclosporiasis Surveillance - United States, 2011-2015. 38
31002104 2019
6
Mitochondrial genome sequence variation as a useful marker for assessing genetic heterogeneity among Cyclospora cayetanensis isolates and source-tracking. 38
30665345 2019
7
Notes from the field: Multiple cyclosporiasis outbreaks - United States, 2018. 38
30476362 2018
8
Notes from the Field: Multiple Cyclosporiasis Outbreaks - United States, 2018. 38
30286055 2018
9
Notes from the Field: Cyclosporiasis Cases Associated with Dining at a Mediterranean-Style Restaurant Chain - Texas, 2017. 38
29851947 2018
10
Molecular detection of Cyclospora cayetanensis in human stool specimens using UNEX-based DNA extraction and real-time PCR. 38
29113617 2018
11
Population genetic characterization of Cyclospora cayetanensis from discrete geographical regions. 38
29274312 2018
12
A hybrid reference-guided de novo assembly approach for generating Cyclospora mitochondrion genomes. 38
29643938 2018
13
Chronic Diarrhea in a Traveler: Cyclosporiasis. 38
28716461 2017
14
Multilocus sequence typing and clonal population genetic structure of Cyclospora cayetanensis in humans. 38
28697813 2017
15
2015 Outbreak of Cyclosporiasis Linked to the Consumption of Imported Sugar Snap Peas in Ontario, Canada. 38
28876133 2017
16
The Prevalence of Cyclospora cayetanensis and Cryptosporidium spp. in Turkish patients infected with HIV-1. 38
28682770 2017
17
Cyclosporiasis in travellers returning to the United Kingdom from Mexico in summer 2017: lessons from the recent past to inform the future. 38
28816651 2017
18
Evaluation of an Improved U.S. Food and Drug Administration Method for the Detection of Cyclospora cayetanensis in Produce Using Real-Time PCR. 38
28590822 2017
19
Detection of Cryptosporidium and Cyclospora Oocysts from Environmental Water for Drinking and Recreational Activities in Sarawak, Malaysia. 38
29234679 2017
20
Comparative sequence analysis of Cyclospora cayetanensis apicoplast genomes originating from diverse geographical regions. 38
27899155 2016
21
Multistate product traceforward investigation to link imported romaine lettuce to a US cyclosporiasis outbreak - Nebraska, Texas, and Florida, June-August 2013. 38
26489400 2016
22
Replication and maintenance of the Plasmodium falciparum apicoplast genome. 38
27338018 2016
23
Elevated Values of Clinically Relevant Transferases Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 14,559 Diseased German Travelers Returning from the Tropics and Subtropics. 38
27215300 2016
24
Parasites. 38
27726821 2016
25
Wide genetic variations at 18S ribosomal RNA locus of Cyclospora cayetanensis isolated from Egyptian patients using high resolution melting curve. 38
27041342 2016
26
Regional investigation of a cyclosporiasis outbreak linked to imported romaine lettuce - Nebraska and Iowa, June-August 2013. 38
26489789 2016
27
Data-driven approach of CUSUM algorithm in temporal aberrant event detection using interactive web applications. 38
27348117 2016
28
Comparative genomics reveals Cyclospora cayetanensis possesses coccidia-like metabolism and invasion components but unique surface antigens. 38
27129308 2016
29
2013 multistate outbreaks of Cyclospora cayetanensis infections associated with fresh produce: focus on the Texas investigations. 38
25865140 2015
30
Genetic similarities between Cyclospora cayetanensis and cecum-infecting avian Eimeria spp. in apicoplast and mitochondrial genomes. 38
26152563 2015
31
Parasitic colitis. 38
26034403 2015
32
Identification and morphologic and molecular characterization of Cyclospora macacae n. sp. from rhesus monkeys in China. 38
25673080 2015
33
Cyclospora cayetanensis in a pediatric hospital in Morelia, México. 38
24957545 2014
34
outbreaks of cyclosporiasis--United States, June-August 2013. 38
24172881 2013
35
Cystoisospora and cyclospora. 38
23982239 2013
36
International notification of cases of cyclosporiasis (call us, maybe?). 38
24005356 2013
37
Notes from the field: use of electronic messaging and the news media to increase case finding during a Cyclospora outbreak - Iowa, July 2013. 38
23903596 2013
38
An outbreak of Cyclospora infection on a cruise ship. 38
22687637 2013
39
A descriptive study of reportable gastrointestinal illnesses in Ontario, Canada, from 2007 to 2009. 38
23145487 2012
40
[Clinical and epidemiological study of intestinal coccidioses in a rural population of a semiarid region from Falcon state, Venezuela]. 38
23248971 2012
41
[Research progress on the biology and epidemiology of Cyclospora cayetanensis]. 38
23072169 2012
42
Population-based active surveillance for Cyclospora infection--United States, Foodborne Diseases Active Surveillance Network (FoodNet), 1997-2009. 38
22572662 2012
43
[Two diarrhea cases caused by Cyclospora cayetanensis]. 38
21935790 2011
44
Surveillance for laboratory-confirmed sporadic cases of cyclosporiasis--United States, 1997-2008. 38
21471951 2011
45
[Notable imported infectious diseases]. 38
21560415 2011
46
[Cyclospora cayetanensis: biology, environmental distribution and transfer]. 38
22159492 2011
47
Current spectrum of malabsorption syndrome in adults in India. 38
21369836 2011
48
A foodborne outbreak of Cyclospora infection in Stockholm, Sweden. 38
20807111 2010
49
[Importance of contact with soil in the transmission of cyclosporosis]. 38
21365872 2010
50
Cyclospora cayetanensis: a review, focusing on some of the remaining questions about cyclosporiasis. 38
20701573 2010

Variations for Cyclosporiasis

Expression for Cyclosporiasis

Search GEO for disease gene expression data for Cyclosporiasis.

Pathways for Cyclosporiasis

Pathways related to Cyclosporiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.74 GGT2 GGT1
2
Show member pathways
11.68 GGT2 GGT1
3
Show member pathways
11.53 GGT2 GGT1
4 11.42 GGT2 GGT1
5
Show member pathways
10.8 GGT2 GGT1
6 10.34 GGT2 GGT1
7 9.98 GGT2 GGT1

GO Terms for Cyclosporiasis

Biological processes related to Cyclosporiasis according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.7 GGTLC3 GGT2 GGT1
2 response to lipopolysaccharide GO:0032496 9.54 GGT2 GGT1
3 regulation of inflammatory response GO:0050727 9.51 GGT2 GGT1
4 response to estradiol GO:0032355 9.5 GGT2 GGT1 CD4
5 response to tumor necrosis factor GO:0034612 9.46 GGT2 GGT1
6 zymogen activation GO:0031638 9.4 GGT2 GGT1
7 regulation of immune system process GO:0002682 9.26 GGT2 GGT1
8 cellular amino acid metabolic process GO:0006520 9.19 GGT1
9 glutathione metabolic process GO:0006749 9.18 GGT1
10 peptide modification GO:0031179 9.16 GGT2 GGT1
11 glutamate metabolic process GO:0006536 9.13 GGT1
12 glutathione catabolic process GO:0006751 9.13 GGTLC3 GGT2 GGT1
13 cysteine biosynthetic process GO:0019344 9.07 GGT1
14 leukotriene D4 biosynthetic process GO:1901750 8.8 GGTLC3 GGT2 GGT1

Molecular functions related to Cyclosporiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidyltransferase activity GO:0000048 8.96 GGT2 GGT1
2 glutathione hydrolase activity GO:0036374 8.8 GGTLC3 GGT2 GGT1

Sources for Cyclosporiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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