MCID: CYC002
MIFTS: 32

Cyclosporiasis

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Cyclosporiasis

MalaCards integrated aliases for Cyclosporiasis:

Name: Cyclosporiasis 12 54 3 45 15 17 74
Cyclosporosis 54 60
Cyclospora Infection 54

Characteristics:

Orphanet epidemiological data:

60
cyclosporosis
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy;

Classifications:

Orphanet: 60  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:12750
ICD9CM 36 007.5
MeSH 45 D021866
NCIt 51 C128409
ICD10 34 A07.4
ICD10 via Orphanet 35 A07.3
Orphanet 60 ORPHA210
UMLS 74 C0343398

Summaries for Cyclosporiasis

Disease Ontology : 12 A coccidiosis that involves infection of the intestine with the parasitic protozoan Cyclospora cayetanensis, which is transmitted by contaminated food and water. The symptoms include watery diarrhea, anorexia, weight loss, abdominal pain, nausea and vomiting, myalgias, low-grade fever, and fatigue.

MalaCards based summary : Cyclosporiasis, also known as cyclosporosis, is related to diarrhea and cryptosporidiosis. An important gene associated with Cyclosporiasis is CD1A (CD1a Molecule), and among its related pathways/superpathways are Selenium Micronutrient Network and Glutathione metabolism. Affiliated tissues include pancreas, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

CDC : 3  

Wikipedia : 77 Cyclosporiasis is a disease caused by infection with Cyclospora cayetanensis, a pathogenic protozoan... more...

Related Diseases for Cyclosporiasis

Graphical network of the top 20 diseases related to Cyclosporiasis:



Diseases related to Cyclosporiasis

Symptoms & Phenotypes for Cyclosporiasis

GenomeRNAi Phenotypes related to Cyclosporiasis according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-128 9.62 GGT2
2 Increased shRNA abundance (Z-score > 2) GR00366-A-130 9.62 GGT1 GGT2
3 Increased shRNA abundance (Z-score > 2) GR00366-A-131 9.62 GGT2
4 Increased shRNA abundance (Z-score > 2) GR00366-A-143 9.62 GGT1 GGT2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.62 GGT1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-24 9.62 GGT2
7 Increased shRNA abundance (Z-score > 2) GR00366-A-7 9.62 GGT1 GGT2

Drugs & Therapeutics for Cyclosporiasis

Search Clinical Trials , NIH Clinical Center for Cyclosporiasis

Cochrane evidence based reviews: cyclosporiasis

Genetic Tests for Cyclosporiasis

Anatomical Context for Cyclosporiasis

MalaCards organs/tissues related to Cyclosporiasis:

42
Pancreas

Publications for Cyclosporiasis

Articles related to Cyclosporiasis:

(show top 50) (show all 82)
# Title Authors Year
1
Human cyclosporiasis. ( 30885589 )
2019
2
Cyclosporiasis Surveillance - United States, 2011-2015. ( 31002104 )
2019
3
Notes from the Field: Cyclosporiasis Cases Associated with Dining at a Mediterranean-Style Restaurant Chain - Texas, 2017. ( 29851947 )
2018
4
Notes from the Field: Multiple Cyclosporiasis Outbreaks - United States, 2018. ( 30286055 )
2018
5
Notes from the field: Multiple cyclosporiasis outbreaks - United States, 2018. ( 30476362 )
2018
6
Chronic Diarrhea in a Traveler: Cyclosporiasis. ( 28716461 )
2017
7
Cyclosporiasis in travellers returning to the United Kingdom from Mexico in summer 2017: lessons from the recent past to inform the future. ( 28816651 )
2017
8
2015 Outbreak of Cyclosporiasis Linked to the Consumption of Imported Sugar Snap Peas in Ontario, Canada. ( 28876133 )
2017
9
Multistate product traceforward investigation to link imported romaine lettuce to a US cyclosporiasis outbreak - Nebraska, Texas, and Florida, June-August 2013. ( 26489400 )
2016
10
Regional investigation of a cyclosporiasis outbreak linked to imported romaine lettuce - Nebraska and Iowa, June-August 2013. ( 26489789 )
2016
11
International notification of cases of cyclosporiasis (call us, maybe?). ( 24005356 )
2013
12
outbreaks of cyclosporiasis--United States, June-August 2013. ( 24172881 )
2013
13
Surveillance for laboratory-confirmed sporadic cases of cyclosporiasis--United States, 1997-2008. ( 21471951 )
2011
14
High occurrence of cyclosporiasis in Istanbul, Turkey, during a dry and warm summer. ( 20416057 )
2010
15
Cyclospora cayetanensis: a review, focusing on some of the remaining questions about cyclosporiasis. ( 20701573 )
2010
16
Cyclosporiasis: an update. ( 19239800 )
2009
17
Challenges of investigating community outbreaks of cyclosporiasis, British Columbia, Canada. ( 19751593 )
2009
18
Use of PCR to improve diagnostic yield in an outbreak of cyclosporiasis in Lima, Peru. ( 18433812 )
2008
19
First Italian case of cyclosporiasis in an immunocompetent woman: local acquired infection. ( 18623995 )
2008
20
Transmission of Cyclospora cayetanensis infection: a review focusing on soil-borne cyclosporiasis. ( 17689579 )
2008
21
Six human cyclosporiasis: with general review. ( 17985572 )
2007
22
Cyclosporiasis: an emerging public health concern around the world and in Africa. ( 17594281 )
2007
23
Efficacy of nitazoxanide for cyclosporiasis in patients with sulfa allergy. ( 17205465 )
2007
24
Incidence of cyclosporiasis in patients with gastrointestinal symptoms in western Turkey. ( 17179908 )
2007
25
Cyclosporiasis: a point source outbreak acquired in Guatemala. ( 17107425 )
2006
26
Outbreak of cyclosporiasis at a naval base in Lima, Peru. ( 16968939 )
2006
27
Cyclosporiasis in an infant. ( 16687871 )
2006
28
Cyclosporiasis outbreak, Indonesia. ( 16229780 )
2005
29
Update on emerging infections: news from the Centers for Disease Control and Prevention. Outbreak of cyclosporiasis associated with snow peas--Pennsylvania, 2004. ( 15855952 )
2005
30
Outbreak of cyclosporiasis in British Columbia associated with imported Thai basil. ( 15724706 )
2005
31
Outbreak of cyclosporiasis associated with snow peas--Pennsylvania, 2004. ( 15385921 )
2004
32
Cyclosporiasis associated with diarrhoea in an immunocompetent patient in Turkey. ( 14970253 )
2004
33
A case of human cyclosporiasis causing traveler's diarrhea after visiting Indonesia. ( 14555830 )
2003
34
Epidemiologic differences between cyclosporiasis and cryptosporidiosis in Peruvian children. ( 12023913 )
2002
35
Cyclosporiasis outbreak in Germany associated with the consumption of salad. ( 12194782 )
2002
36
Outbreak of cyclosporiasis associated with imported raspberries, Philadelphia, Pennsylvania, 2000. ( 12141962 )
2002
37
An imported case of cyclosporiasis in Japan. ( 11904997 )
2002
38
Reiter syndrome following protracted symptoms of Cyclospora infection. ( 11384527 )
2001
39
Reiter syndrome following protracted symptoms of Cyclospora infection. ( 11747750 )
2001
40
Outbreak of cyclosporiasis associated with basil in Missouri in 1999. ( 11264028 )
2001
41
Cyclospora infection in acquired immunodeficiency syndrome. ( 11273176 )
2000
42
An outbreak of cyclosporiasis in 1996 associated with consumption of fresh berries- Ontario. ( 18159270 )
2000
43
Cyclospora cayetanensis: a review, focusing on the outbreaks of cyclosporiasis in the 1990s. ( 11049789 )
2000
44
The impact of health communication and enhanced laboratory-based surveillance on detection of cyclosporiasis outbreaks in California. ( 10756158 )
2000
45
Foodborne outbreaks of cyclosporiasis have arisen in North America. Is the United Kingdom at risk? ( 10743320 )
2000
46
First reported three cases of cyclosporiasis in Iraq. ( 10983548 )
1999
47
The first reported cluster of food-borne cyclosporiasis in Canada. ( 10680266 )
1999
48
Cyclosporiasis associated with imported raspberries, Florida, 1996. ( 10590765 )
1999
49
Cyclosporiasis: clinical and histopathologic correlates. ( 10451156 )
1999
50
Lessons learned again: cyclosporiasis and raspberries. ( 10049203 )
1999

Variations for Cyclosporiasis

Expression for Cyclosporiasis

Search GEO for disease gene expression data for Cyclosporiasis.

Pathways for Cyclosporiasis

Pathways related to Cyclosporiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.74 GGT1 GGT2
2
Show member pathways
11.68 GGT1 GGT2
3
Show member pathways
11.53 GGT1 GGT2
4 11.42 GGT1 GGT2
5
Show member pathways
10.8 GGT1 GGT2
6 10.34 GGT1 GGT2
7 9.98 GGT1 GGT2

GO Terms for Cyclosporiasis

Biological processes related to Cyclosporiasis according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.7 GGT1 GGT2 GGTLC3
2 response to lipopolysaccharide GO:0032496 9.54 GGT1 GGT2
3 response to estradiol GO:0032355 9.51 GGT1 GGT2
4 regulation of inflammatory response GO:0050727 9.49 GGT1 GGT2
5 cellular amino acid metabolic process GO:0006520 9.48 GGT1 GGT2
6 glutathione metabolic process GO:0006749 9.46 GGT1 GGT2
7 response to tumor necrosis factor GO:0034612 9.43 GGT1 GGT2
8 glutamate metabolic process GO:0006536 9.4 GGT1 GGT2
9 zymogen activation GO:0031638 9.37 GGT1 GGT2
10 cysteine biosynthetic process GO:0019344 9.32 GGT1 GGT2
11 regulation of immune system process GO:0002682 9.26 GGT1 GGT2
12 peptide modification GO:0031179 9.16 GGT1 GGT2
13 glutathione catabolic process GO:0006751 9.13 GGT1 GGT2 GGTLC3
14 leukotriene D4 biosynthetic process GO:1901750 8.8 GGT1 GGT2 GGTLC3

Molecular functions related to Cyclosporiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidyltransferase activity GO:0000048 8.96 GGT1 GGT2
2 glutathione hydrolase activity GO:0036374 8.8 GGT1 GGT2 GGTLC3

Sources for Cyclosporiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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