MCID: CYC002
MIFTS: 33

Cyclosporiasis

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Cyclosporiasis

MalaCards integrated aliases for Cyclosporiasis:

Name: Cyclosporiasis 12 53 3 44 15 73
Cyclosporosis 53 59
Cyclospora Infection 53

Characteristics:

Orphanet epidemiological data:

59
cyclosporosis
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy;

Classifications:

Orphanet: 59  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:12750
ICD10 33 A07.4
ICD9CM 35 007.5
MeSH 44 D021866
NCIt 50 C128409
Orphanet 59 ORPHA210
ICD10 via Orphanet 34 A07.3
UMLS 73 C0343398

Summaries for Cyclosporiasis

Disease Ontology : 12 A coccidiosis that involves infection of the intestine with the parasitic protozoan Cyclospora cayetanensis, which is transmitted by contaminated food and water. The symptoms include watery diarrhea, anorexia, weight loss, abdominal pain, nausea and vomiting, myalgias, low-grade fever, and fatigue.

MalaCards based summary : Cyclosporiasis, also known as cyclosporosis, is related to diarrhea and cryptosporidiosis. An important gene associated with Cyclosporiasis is CD1A (CD1a Molecule), and among its related pathways/superpathways are Selenium Micronutrient Network and Glutathione metabolism. Affiliated tissues include pancreas, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

CDC : 3  

Wikipedia : 76 Cyclosporiasis is a disease caused by infection with Cyclospora cayetanensis, a pathogenic protozoan... more...

Related Diseases for Cyclosporiasis

Graphical network of the top 20 diseases related to Cyclosporiasis:



Diseases related to Cyclosporiasis

Symptoms & Phenotypes for Cyclosporiasis

GenomeRNAi Phenotypes related to Cyclosporiasis according to GeneCards Suite gene sharing:

26 (show all 16)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-128 9.8 GGT2
2 Increased shRNA abundance (Z-score > 2) GR00366-A-130 9.8 GGT1 GGT2
3 Increased shRNA abundance (Z-score > 2) GR00366-A-131 9.8 GGT2
4 Increased shRNA abundance (Z-score > 2) GR00366-A-143 9.8 GGT1 GGT2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.8 GGT1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-24 9.8 GGT2
7 Increased shRNA abundance (Z-score > 2) GR00366-A-7 9.8 GGT1 GGT2
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.65 GGT1
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-173 9.65 GGT1
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.65 GGT1 GGT2
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-211 9.65 GGT1
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-213 9.65 GGT2
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-26 9.65 GGT1
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.65 GGT2
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-62 9.65 GGT2
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.65 GGT1

Drugs & Therapeutics for Cyclosporiasis

Search Clinical Trials , NIH Clinical Center for Cyclosporiasis

Cochrane evidence based reviews: cyclosporiasis

Genetic Tests for Cyclosporiasis

Anatomical Context for Cyclosporiasis

MalaCards organs/tissues related to Cyclosporiasis:

41
Pancreas

Publications for Cyclosporiasis

Articles related to Cyclosporiasis:

(show top 50) (show all 79)
# Title Authors Year
1
Notes from the Field: Cyclosporiasis Cases Associated with Dining at a Mediterranean-Style Restaurant Chain - Texas, 2017. ( 29851947 )
2018
2
Notes from the Field: Multiple Cyclosporiasis Outbreaks - United States, 2018. ( 30286055 )
2018
3
Notes from the field: Multiple cyclosporiasis outbreaks - United States, 2018. ( 30476362 )
2018
4
2015 Outbreak of Cyclosporiasis Linked to the Consumption of Imported Sugar Snap Peas in Ontario, Canada. ( 28876133 )
2017
5
Chronic Diarrhea in a Traveler: Cyclosporiasis. ( 28716461 )
2017
6
Cyclosporiasis in travellers returning to the United Kingdom from Mexico in summer 2017: lessons from the recent past to inform the future. ( 28816651 )
2017
7
Regional investigation of a cyclosporiasis outbreak linked to imported romaine lettuce - Nebraska and Iowa, June-August 2013. ( 26489789 )
2016
8
Multistate product traceforward investigation to link imported romaine lettuce to a US cyclosporiasis outbreak - Nebraska, Texas, and Florida, June-August 2013. ( 26489400 )
2015
9
International notification of cases of cyclosporiasis (call us, maybe?). ( 24005356 )
2013
10
outbreaks of cyclosporiasis--United States, June-August 2013. ( 24172881 )
2013
11
Surveillance for laboratory-confirmed sporadic cases of cyclosporiasis--United States, 1997-2008. ( 21471951 )
2011
12
Cyclospora cayetanensis: a review, focusing on some of the remaining questions about cyclosporiasis. ( 20701573 )
2010
13
High occurrence of cyclosporiasis in Istanbul, Turkey, during a dry and warm summer. ( 20416057 )
2010
14
Challenges of investigating community outbreaks of cyclosporiasis, British Columbia, Canada. ( 19751593 )
2009
15
Cyclosporiasis: an update. ( 19239800 )
2009
16
First Italian case of cyclosporiasis in an immunocompetent woman: local acquired infection. ( 18623995 )
2008
17
Use of PCR to improve diagnostic yield in an outbreak of cyclosporiasis in Lima, Peru. ( 18433812 )
2008
18
Transmission of Cyclospora cayetanensis infection: a review focusing on soil-borne cyclosporiasis. ( 17689579 )
2008
19
Efficacy of nitazoxanide for cyclosporiasis in patients with sulfa allergy. ( 17205465 )
2007
20
Incidence of cyclosporiasis in patients with gastrointestinal symptoms in western Turkey. ( 17179908 )
2007
21
Six human cyclosporiasis: with general review. ( 17985572 )
2007
22
Cyclosporiasis: an emerging public health concern around the world and in Africa. ( 17594281 )
2007
23
Outbreak of cyclosporiasis at a naval base in Lima, Peru. ( 16968939 )
2006
24
Cyclosporiasis: a point source outbreak acquired in Guatemala. ( 17107425 )
2006
25
Cyclosporiasis in an infant. ( 16687871 )
2006
26
Update on emerging infections: news from the Centers for Disease Control and Prevention. Outbreak of cyclosporiasis associated with snow peas--Pennsylvania, 2004. ( 15855952 )
2005
27
Outbreak of cyclosporiasis in British Columbia associated with imported Thai basil. ( 15724706 )
2005
28
Cyclosporiasis outbreak, Indonesia. ( 16229780 )
2005
29
Outbreak of cyclosporiasis associated with snow peas--Pennsylvania, 2004. ( 15385921 )
2004
30
Cyclosporiasis associated with diarrhoea in an immunocompetent patient in Turkey. ( 14970253 )
2004
31
A case of human cyclosporiasis causing traveler's diarrhea after visiting Indonesia. ( 14555830 )
2003
32
Cyclosporiasis outbreak in Germany associated with the consumption of salad. ( 12194782 )
2002
33
An imported case of cyclosporiasis in Japan. ( 11904997 )
2002
34
Epidemiologic differences between cyclosporiasis and cryptosporidiosis in Peruvian children. ( 12023913 )
2002
35
Outbreak of cyclosporiasis associated with imported raspberries, Philadelphia, Pennsylvania, 2000. ( 12141962 )
2002
36
Outbreak of cyclosporiasis associated with basil in Missouri in 1999. ( 11264028 )
2001
37
Reiter syndrome following protracted symptoms of Cyclospora infection. ( 11384527 )
2001
38
Reiter syndrome following protracted symptoms of Cyclospora infection. ( 11747750 )
2001
39
Foodborne outbreaks of cyclosporiasis have arisen in North America. Is the United Kingdom at risk? ( 10743320 )
2000
40
Cyclospora cayetanensis: a review, focusing on the outbreaks of cyclosporiasis in the 1990s. ( 11049789 )
2000
41
The impact of health communication and enhanced laboratory-based surveillance on detection of cyclosporiasis outbreaks in California. ( 10756158 )
2000
42
An outbreak of cyclosporiasis in 1996 associated with consumption of fresh berries- Ontario. ( 18159270 )
2000
43
Cyclospora infection in acquired immunodeficiency syndrome. ( 11273176 )
2000
44
Cyclosporiasis associated with imported raspberries, Florida, 1996. ( 10590765 )
1999
45
Cyclosporiasis: clinical and histopathologic correlates. ( 10451156 )
1999
46
First reported three cases of cyclosporiasis in Iraq. ( 10983548 )
1999
47
The return of Cyclospora in 1997: another outbreak of cyclosporiasis in North America associated with imported raspberries. Cyclospora Working Group. ( 10049199 )
1999
48
Lessons learned again: cyclosporiasis and raspberries. ( 10049203 )
1999
49
The first reported cluster of food-borne cyclosporiasis in Canada. ( 10680266 )
1999
50
Cyclosporiasis in a HIV-positive patient. ( 10968174 )
1998

Variations for Cyclosporiasis

Expression for Cyclosporiasis

Search GEO for disease gene expression data for Cyclosporiasis.

Pathways for Cyclosporiasis

Pathways related to Cyclosporiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.74 GGT1 GGT2
2
Show member pathways
11.68 GGT1 GGT2
3
Show member pathways
11.53 GGT1 GGT2
4 11.42 GGT1 GGT2
5
Show member pathways
10.8 GGT1 GGT2
6 10.34 GGT1 GGT2
7 9.98 GGT1 GGT2

GO Terms for Cyclosporiasis

Biological processes related to Cyclosporiasis according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.52 GGT1 GGT2
2 response to estradiol GO:0032355 9.51 GGT1 GGT2
3 regulation of inflammatory response GO:0050727 9.49 GGT1 GGT2
4 cellular amino acid metabolic process GO:0006520 9.48 GGT1 GGT2
5 glutathione metabolic process GO:0006749 9.46 GGT1 GGT2
6 response to tumor necrosis factor GO:0034612 9.43 GGT1 GGT2
7 glutamate metabolic process GO:0006536 9.4 GGT1 GGT2
8 zymogen activation GO:0031638 9.37 GGT1 GGT2
9 glutathione catabolic process GO:0006751 9.32 GGT1 GGT2
10 leukotriene D4 biosynthetic process GO:1901750 9.26 GGT1 GGT2
11 cysteine biosynthetic process GO:0019344 9.16 GGT1 GGT2
12 regulation of immune system process GO:0002682 8.96 GGT1 GGT2
13 peptide modification GO:0031179 8.62 GGT1 GGT2

Molecular functions related to Cyclosporiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glutathione hydrolase activity GO:0036374 8.96 GGT1 GGT2
2 peptidyltransferase activity GO:0000048 8.62 GGT1 GGT2

Sources for Cyclosporiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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