MCID: CYS015
MIFTS: 31

Cystadenofibroma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases
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Aliases & Classifications for Cystadenofibroma

MalaCards integrated aliases for Cystadenofibroma:

Name: Cystadenofibroma 11 14 71

Classifications:



External Ids:

Disease Ontology 11 DOID:5482
MeSH 43 D062625
NCIt 49 C8985
SNOMED-CT 68 2962009
UMLS 71 C0334317

Summaries for Cystadenofibroma

Disease Ontology: 11 An ovarian benign neoplasm that is composed of epithelial ovarian tissue.

MalaCards based summary: Cystadenofibroma is related to mucinous cystadenofibroma and clear cell cystadenofibroma. An important gene associated with Cystadenofibroma is MIA2 (MIA SH3 Domain ER Export Factor 2), and among its related pathways/superpathways are Epithelial to mesenchymal transition in colorectal cancer and NGF Pathway. Affiliated tissues include ovary, lymph node and appendix, and related phenotype is liver/biliary system.

Related Diseases for Cystadenofibroma

Diseases related to Cystadenofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 456)
# Related Disease Score Top Affiliating Genes
1 mucinous cystadenofibroma 32.6 PAX8 KRT7
2 clear cell cystadenofibroma 32.1 TP53 CALB2
3 ovarian serous cystadenofibroma 31.2 WT1 TP53 PAX8 KRT7 CALB2
4 papillary carcinoma 30.1 PAX8 KRT7 CALB2
5 struma ovarii 30.0 KRT7 KRAS
6 papillary adenofibroma 29.9 WT1 PAX8 CALB2
7 cystadenoma 29.8 MME KRT7 CALB2 AFP
8 adenoid squamous cell carcinoma 29.7 TP53 KRT7
9 ovarian serous cystadenocarcinoma 29.5 TP53 PAX8 KRAS HRAS
10 endometrial adenocarcinoma 29.3 TP53 PAX8 KRT7 KRAS
11 adenocarcinoma 29.2 TP53 KRT7 KRAS HRAS
12 colorectal adenocarcinoma 29.1 TP53 KRT7 KRAS HRAS
13 endometrial stromal sarcoma 29.1 WT1 TP53 MME CALB2
14 myoma 29.1 TP53 MME KRAS CALB2
15 adenofibroma 29.1 WT1 TP53 PAX8 MME KRT7 KRAS
16 teratoma 28.8 TP53 KRT7 KRAS CALB2 AFP
17 endosalpingiosis 28.4 WT1 TP53 PAX8 KRT7 KRAS HRAS
18 serous cystadenocarcinoma 28.4 WT1 TP53 PAX8 KRT7 KRAS HRAS
19 endometrial cancer 28.2 WT1 TP53 MME KRT7 KRAS HRAS
20 ovarian mucinous cystadenofibroma 11.2
21 fallopian tube cystadenofibroma 11.2
22 ovarian endometrioid cystadenofibroma 11.1
23 clear cell adenofibroma 11.1
24 ovarian clear cell cystadenofibroma 11.1
25 rete ovarii cystadenofibroma 11.1
26 urethra clear cell adenocarcinoma 10.3 PAX8 KRT7
27 urethra adenocarcinoma 10.3 PAX8 KRT7
28 bladder benign neoplasm 10.3 PAX8 KRT7
29 urethra cancer 10.3 PAX8 KRT7
30 urethral diverticulum 10.3 PAX8 KRT7
31 malignant epithelial mesothelioma 10.3 KRT7 CALB2
32 microinvasive cervical squamous cell carcinoma 10.3 WT1 KRT7
33 epithelial predominant wilms' tumor 10.3 WT1 KRT7
34 ovarian wilms' cancer 10.3 WT1 CALB2
35 nephrogenic adenofibroma 10.3 WT1 KRT7
36 ovarian mucinous adenocarcinoma 10.3 PAX8 KRT7
37 thymus large cell carcinoma 10.3 PAX8 KRT7
38 lymphohistiocytoid mesothelioma 10.3 PAX8 CALB2
39 biphasic synovial sarcoma 10.2 KRT7 CALB2
40 ovarian brenner tumor 10.2 WT1 KRT7
41 medullary colon carcinoma 10.2 KRT7 CALB2
42 perivascular epithelioid cell tumor 10.2 PAX8 MME
43 rectosigmoid junction neoplasm 10.2 KRT7 KRAS
44 nasal cavity adenocarcinoma 10.2 KRT7 HRAS
45 ovarian small cell carcinoma 10.2 WT1 CALB2
46 hidradenoma 10.2 MME KRT7
47 breast adenomyoepithelioma 10.2 KRT7 HRAS
48 breast myoepithelial neoplasm 10.2 KRT7 HRAS
49 thymus sarcomatoid carcinoma 10.2 WT1 CALB2
50 fallopian tube serous adenocarcinoma 10.2 WT1 CALB2

Graphical network of the top 20 diseases related to Cystadenofibroma:



Diseases related to Cystadenofibroma

Symptoms & Phenotypes for Cystadenofibroma

MGI Mouse Phenotypes related to Cystadenofibroma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 liver/biliary system MP:0005370 9.1 AFP KRAS MIA2 MME TP53 WT1

Drugs & Therapeutics for Cystadenofibroma

Search Clinical Trials, NIH Clinical Center for Cystadenofibroma

Genetic Tests for Cystadenofibroma

Anatomical Context for Cystadenofibroma

Organs/tissues related to Cystadenofibroma:

MalaCards : Ovary, Lymph Node, Appendix, Breast, Kidney, Liver, Skin

Publications for Cystadenofibroma

Articles related to Cystadenofibroma:

(show top 50) (show all 176)
# Title Authors PMID Year
1
MRI of Borderline Epithelial Ovarian Tumors: Pathologic Correlation and Diagnostic Challenges. 62
36083804 2022
2
Ovarian remnant syndrome with paraintestinal ovarian serous cystadenofibroma arose 30 years after bilateral salpingo-oophorectomy: A case report. 62
36343074 2022
3
A Rare Case of Bilateral Serous Cystadenofibroma in a Malignant Disguise. 62
36448072 2022
4
Features of cystadenofibroma on magnetic resonance imaging: an update using the O-RADS lexicon and considering diffusion-weighted and perfusion imaging. 62
35797789 2022
5
Somatic mutation analysis of Mesonephric-Like adenocarcinoma and associated putative precursor Lesions: Insight into pathogenesis and potential molecular treatment targets. 62
35880223 2022
6
Mucinous Tumor Coexisting With Mesonephric-like Proliferation/Tumor in the Ovary: A Novel Association. 62
35405716 2022
7
Cystadenofibroma with Mullerian-Type Epithelium and Stroma in the Liver: A Report of an Unusual Diagnosis and Discussion of Possible Etiologies. 62
35899292 2022
8
Endocrine cell micronests in an ovarian mucinous borderline tumor: a potential diagnostic pitfall for microinvasion. 62
35422044 2022
9
Blue mass in pelvis: serous cystadenofibroma of peritoneum. 62
34533245 2022
10
Transvaginal Natural Orifice Transluminal Endoscopic Surgery for Surgical Staging of Early-Stage Ovarian Cancers: A Report of Two Cases. 62
35372471 2022
11
Müllerian Mucinous Cystadenomas of the Ovary: A Report of 25 Cases of an Unheralded Benign Ovarian Neoplasm Often Associated With Endometriosis and a Brief Consideration of Neoplasms Arising From the Latter. 62
33577227 2022
12
A case of ovarian serous cystadenofibroma with scattered lesions in pelvic cavity, like malignant disseminations. 62
34490687 2021
13
Pearls and Potential Pitfalls for Correct Diagnosis of Ovarian Cystadenofibroma in MRI: A Pictorial Essay. 62
34668348 2021
14
A ruptured ovarian cystadenofibroma presenting with life-threatening sepsis and an incidental synchronous endometrial stromal sarcoma. 62
34844964 2021
15
Serous papillary cystadenofibroma of vulva: A histopathological surprise. 62
34000491 2021
16
Low-grade serous carcinoma with extensive osseous metaplasia arising from ovarian serous cystadenofibroma. 62
33553558 2021
17
Ovarian seromucinous tumors: clinicopathological features of 10 cases with a detailed review of the literature. 62
33736662 2021
18
Multimodality Imaging Approach to Ovarian Neoplasms with Pathologic Correlation. 62
33186060 2021
19
Determining the significance of psammoma bodies in pelvic washings: A 10-year retrospective review. 62
32931128 2021
20
Cholesterol granuloma mimicking ovarian cancer. 62
34239676 2021
21
Coexistence of genital tuberculosis and ovarian serous cystadenofibroma in a young female patient: a case report. 62
33045892 2020
22
OVARIAN CANCER TREATMENT OPTIMIZATION: THE COMPLEX ANALYSIS OF THE RESULTS OF CYTOREDUCTIVE SURGERY, MICROSCOPIC MALIGNANCY AND T-LYMPHOCYTIC INFILTRATION OF THE TUMOR. 62
33270572 2020
23
Coexistence of ovarian serous papillary cystadenofibroma and type A insulin resistance syndrome in a 14-year-old girl: A case report. 62
32874990 2020
24
Psammoma bodies in Papanicolaou tests and associated factors to predict an underlying malignancy: a clinicopathological analysis of 10 cases. 62
32376242 2020
25
Borderline serous ovarian neoplasm: case report of a diagnostic challenge in intraoperative frozen sections. 62
32461918 2020
26
Tumor-to-Tumor Metastasis of Colorectal Adenocarcinoma to Ovarian Cystadenofibroma: A Case Report and Review of the Literature. 62
30882401 2020
27
Papillary Cystadenofibroma of Fallopian Tube: Case Report with a Literature Review. 62
32317841 2020
28
Imaging in gynecological disease (16): clinical and ultrasound characteristics of serous cystadenofibromas in adnexa. 62
30937992 2019
29
Incidental Gynecologic Tract Neoplasms in Women Undergoing Anterior Pelvic Exenteration for Urothelial Carcinoma. 62
29257039 2019
30
Laparoscopic excision of a retroperitoneal mucinous cystic neoplasm: A case report. 62
31421556 2019
31
Serous cystadenofibroma misdiagnosed as an ovarian malignancy. 62
30567152 2018
32
Unusual case of anti-N-methyl-D-aspartic acid-receptor (NMDA-R) encephalitis and autoimmune polyglandular syndrome (APS). 62
29724875 2018
33
Microscopic Heterotopic Extraovarian Sex Cord-Stromal Proliferations: Expanding the Histologic Spectrum. 62
28319576 2018
34
Three-dimensional ultrasound and HDlive in tubal serous cystadenofibroma: a case report and literature review. 62
29197922 2017
35
Ovarian masses with papillary projections diagnosed and removed during pregnancy: ultrasound features and histological diagnosis. 62
27484484 2017
36
Diagnostic Imaging of Pregnant Women - The Role of Magnetic Resonance Imaging. 62
28507642 2017
37
Large ovarian cystadenofibroma causing large bowel obstruction in a patient with Klippel-Feil syndrome-A case report. 62
26780471 2016
38
Serous Tubal Intraepithelial Carcinoma (STIC)-like Lesions Arising in Ovarian Serous Cystadenofibroma: Report of 2 Cases. 62
26107558 2015
39
Serous papillary cystadenofibroma of the fallopian tube: A case report and short review of literature. 62
26549083 2015
40
Cystadenofibromas: Can transvaginal ultrasound appearance reduce some surgical interventions? 62
25271400 2015
41
Endosalpingiosis in conjunction with ovarian serous cystadenoma mimicking metastatic ovarian malignancy. 62
25180540 2014
42
Prevalence of extrauterine pelvic lesions on transvaginal ultrasound in asymptomatic 20-39-year-old women. 62
24375888 2014
43
HDlive rendering image of adnexal tumors: preliminary report. 62
27277771 2014
44
Complete androgen insensitivity syndrome with a large gonadal serous papillary cystadenofibroma. 62
25191030 2014
45
A case of mucinous cystadenofibroma of the ovary. 62
24772358 2014
46
An unusual case of a borderline Brenner tumor associated with bilateral serous cystadenoma and endometrial carcinoma. 62
24791367 2014
47
Large functional benign endometroid cystadenofibroma of the ovary leading to endometrial cystic glandular hyperplasia and postmenopausal bleeding. 62
23761571 2013
48
Single-incision pediatric endosurgery for ovarian pathology. 62
23402287 2013
49
Anti-N-methyl-d-aspartate encephalitis with ovarian cystadenofibroma. 62
23419475 2013
50
Ovarian benign clear cell adenofibroma in a patient with premature ovarian failure after 8-year hormone replacement therapy. 62
23153077 2013

Variations for Cystadenofibroma

Expression for Cystadenofibroma

Search GEO for disease gene expression data for Cystadenofibroma.

Pathways for Cystadenofibroma

GO Terms for Cystadenofibroma

Biological processes related to Cystadenofibroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Ras protein signal transduction GO:0007265 9.8 TP53 KRAS HRAS
2 neuron apoptotic process GO:0051402 9.73 TP53 KRAS HRAS
3 cellular response to gonadotropin stimulus GO:0071371 9.46 WT1 PAX8
4 metanephric S-shaped body morphogenesis GO:0072284 9.26 WT1 PAX8
5 metanephric epithelium development GO:0072207 8.92 WT1 PAX8

Sources for Cystadenofibroma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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