MCID: CYS004
MIFTS: 37

Cystic Basal Cell Carcinoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Cystic Basal Cell Carcinoma

MalaCards integrated aliases for Cystic Basal Cell Carcinoma:

Name: Cystic Basal Cell Carcinoma 12 15 70
Skin Cystic Basal Cell Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4302
UMLS 70 C1275193

Summaries for Cystic Basal Cell Carcinoma

MalaCards based summary : Cystic Basal Cell Carcinoma, also known as skin cystic basal cell carcinoma, is related to hidrocystoma and adenoid cystic carcinoma. An important gene associated with Cystic Basal Cell Carcinoma is KRT20 (Keratin 20), and among its related pathways/superpathways are Estrogen signaling pathway (KEGG) and Keratinization. Affiliated tissues include breast, skin and lung, and related phenotype is digestive/alimentary.

Related Diseases for Cystic Basal Cell Carcinoma

Diseases related to Cystic Basal Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 421)
# Related Disease Score Top Affiliating Genes
1 hidrocystoma 29.9 PIP KRT7 KRT15 CEACAM5
2 adenoid cystic carcinoma 29.8 TP63 KRT7 KRT5 KRT20 KRT14
3 basal cell carcinoma 29.0 TP63 TCHH SYP PTCH1 KRT7 KRT5
4 skin carcinoma 27.7 SYP PTGER4 PTCH1 PIP KRT7 KRT5
5 bile duct adenoma 10.4 KRT7 KRT20
6 nephrogenic adenoma 10.4 TP63 KRT7
7 bladder benign neoplasm 10.4 KRT7 KRT20
8 nephrogenic adenoma of urinary bladder 10.4 KRT7 KRT20
9 atrophic vulva 10.4 KRT7 KRT20
10 cystitis cystica 10.4 KRT7 KRT20
11 jejunal cancer 10.4 KRT7 KRT20
12 intratubular embryonal carcinoma 10.4 KRT7 KRT20
13 papillary transitional carcinoma 10.4 KRT7 KRT20
14 acanthoma 10.4 TCHH KRT5
15 supine hypotensive syndrome 10.4 KRT7 KRT20
16 mucinous bronchioloalveolar adenocarcinoma 10.4 KRT7 KRT20
17 jejunal adenocarcinoma 10.4 KRT7 KRT20
18 acute orbital inflammation 10.4 KRT7 KRT20
19 ureter squamous cell carcinoma 10.4 KRT7 KRT5
20 morpheaform basal cell carcinoma 10.4 KRT20 KRT15
21 glandular cystitis 10.4 KRT7 KRT20
22 inverted transitional papilloma 10.4 KRT7 KRT5
23 nipples, supernumerary 10.4 PIP KRT20
24 infiltrative basal cell carcinoma 10.4 KRT20 KRT15
25 subareolar duct papillomatosis 10.4 KRT7 KRT5
26 nipple benign neoplasm 10.4 KRT7 KRT5
27 microinvasive cervical squamous cell carcinoma 10.4 KRT7 KRT5
28 lung acinar adenocarcinoma 10.4 PIP KRT20
29 anal canal paget's disease 10.4 PIP KRT7
30 gastric signet ring cell adenocarcinoma 10.4 PIP KRT7
31 ovarian brenner tumor 10.4 KRT7 KRT20
32 lung clear cell carcinoma 10.3 KRT7 KRT5
33 bladder clear cell adenocarcinoma 10.3 KRT7 KRT20
34 bartholin's gland disease 10.3 PIP KRT7
35 bartholin's gland carcinoma 10.3 PIP KRT7
36 gastric squamous cell carcinoma 10.3 KRT7 KRT5
37 anus basaloid carcinoma 10.3 PTGER4 KRT7
38 rete testis neoplasm 10.3 PTGER4 KRT7
39 rete testis adenocarcinoma 10.3 PTGER4 KRT7
40 middle ear adenocarcinoma 10.3 KRT7 KRT5
41 balloon cell malignant melanoma 10.3 KRT7 KRT5
42 pregnancy adenoma 10.3 LALBA KRT5
43 erysipeloid 10.3 PIP KRT7
44 cystadenofibroma 10.3 KRT7 KRT5
45 trachea carcinoma 10.3 KRT7 KRT5
46 mucinous stomach adenocarcinoma 10.3 KRT7 KRT5
47 acute thyroiditis 10.3 PIP LALBA
48 solid adenocarcinoma with mucin production 10.3 KRT7 KRT5
49 sarcomatoid basal cell carcinoma 10.3 PTGER4 KRT5
50 breast adenomyoepithelioma 10.3 KRT5 KRT14

Graphical network of the top 20 diseases related to Cystic Basal Cell Carcinoma:



Diseases related to Cystic Basal Cell Carcinoma

Symptoms & Phenotypes for Cystic Basal Cell Carcinoma

MGI Mouse Phenotypes related to Cystic Basal Cell Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.17 B2M KRT14 KRT15 KRT5 PIP PTCH1

Drugs & Therapeutics for Cystic Basal Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Cystic Basal Cell Carcinoma

Genetic Tests for Cystic Basal Cell Carcinoma

Anatomical Context for Cystic Basal Cell Carcinoma

MalaCards organs/tissues related to Cystic Basal Cell Carcinoma:

40
Breast, Skin, Lung, Appendix, Pineal, Thymus, Colon

Publications for Cystic Basal Cell Carcinoma

Articles related to Cystic Basal Cell Carcinoma:

(show all 21)
# Title Authors PMID Year
1
Adenoid Cystic Basal Cell Carcinoma Arising in Rhinophyma. 61
33304635 2020
2
[A case study of bilateral cystic basal cell carcinoma in an albino]. 61
31762910 2019
3
Primary cutaneous cribriform apocrine carcinoma: Case report and literature review. 61
29735815 2018
4
Nodular Cystic Basal Cell Carcinoma of the Trunk: a Diagnostic Dilemma in an Unsuspecting Youth. 61
29563940 2017
5
[Primary cutaneous cribriform apocrine carcinoma : An underdiagnosed entity?]. 61
27270583 2016
6
Arborizing vessels under dermoscopy: a case of cellular neurothekeoma instead of basal cell carcinoma. 61
23552002 2013
7
A Case of Cystic Basal Cell Carcinoma Which Shows a Homogenous Blue/Black Area under Dermatoscopy. 61
21151522 2011
8
How to diagnose nonpigmented skin tumors: a review of vascular structures seen with dermoscopy: part II. Nonmelanocytic skin tumors. 61
20708470 2010
9
Giant cystic basal cell carcinoma mimicking epidermal cyst. 61
19712283 2009
10
[Adenoid cystic/basal cell carcinoma of the prostate:case report]. 61
21086341 2008
11
Adenoid cystic/basal cell carcinoma of the prostate. 61
18295260 2008
12
Adenoid cystic/basal cell carcinoma of the prostate: review and update. 61
17425398 2007
13
Adenoid cystic/basal cell carcinoma of the prostate strongly expresses HER-2/neu. 61
17142577 2006
14
Cystic basal cell carcinoma or hidrocytoma? The use of an excisional biopsy in a histopathologically challenging case. 61
14726825 2004
15
Adenoid cystic/basal cell carcinoma of the prostate: clinicopathologic findings in 19 cases. 61
14657711 2003
16
Primary basal cell carcinoma of the caruncle. 61
9790642 1998
17
Cystic basal cell carcinoma of the orbit and eyelids. 61
9558672 1998
18
Human papillomavirus and c-myc/c-erbB2 in uterine and vulvar lesions. 61
1661047 1991
19
Cutaneous basal cell carcinoma of vulva. 61
1192371 1975
20
SQUAMOUS AND ADENOID CYSTIC BASAL CELL CARCINOMA OF THE CERVIX UTERI. 61
14114382 1964
21
Adenoid cystic basal cell carcinoma (adenocarcinoma); report of a case. 61
14815934 1951

Variations for Cystic Basal Cell Carcinoma

Cosmic variations for Cystic Basal Cell Carcinoma:

9 (show top 50) (show all 3424)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM84510986 ZNF276 skin,NS,carcinoma,basal cell carcinoma c.*940C>T p.? 16:89739186-89739186 3
2 COSM149268805 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.1261G>A p.G421R 16:72958885-72958885 3
3 COSM87274302 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.1655C>T p.S552F 16:72958491-72958491 3
4 COSM87270496 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.10847C>T p.S3616F 16:72787429-72787429 3
5 COSM149259613 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.10847C>T p.S3616F 16:72787429-72787429 3
6 COSM149268792 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.5825G>A p.G1942E 16:72796857-72796857 3
7 COSM87274307 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.1261G>A p.G421R 16:72958885-72958885 3
8 COSM149268800 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.1655C>T p.S552F 16:72958491-72958491 3
9 COSM87273325 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.2084C>T p.P695L 16:72958062-72958062 3
10 COSM149304906 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.1991C>T p.S664F 16:72958155-72958155 3
11 COSM87296537 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.11050G>A p.D3684N 16:72787226-72787226 3
12 COSM102023150 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.-23-7526C>T p.? 16:72958491-72958491 3
13 COSM102023155 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.-23-7920G>A p.? 16:72958885-72958885 3
14 COSM102019420 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.8105C>T p.S2702F 16:72787429-72787429 3
15 COSM149331772 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.11050G>A p.D3684N 16:72787226-72787226 3
16 COSM102023144 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.3083G>A p.G1028E 16:72796857-72796857 3
17 COSM102047764 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.8308G>A p.D2770N 16:72787226-72787226 3
18 COSM87286441 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.1991C>T p.S664F 16:72958155-72958155 3
19 COSM102036925 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.-23-7190C>T p.? 16:72958155-72958155 3
20 COSM149266372 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.2084C>T p.P695L 16:72958062-72958062 3
21 COSM102022243 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.-23-7097C>T p.? 16:72958062-72958062 3
22 COSM87274293 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.5825G>A p.G1942E 16:72796857-72796857 3
23 COSM104882801 XPO1 skin,NS,carcinoma,basal cell carcinoma c.782G>A p.R261Q 2:61496985-61496985 3
24 COSM104236272 XPO1 skin,NS,carcinoma,basal cell carcinoma c.782G>A p.R261Q 2:61496985-61496985 3
25 COSM101976974 XPO1 skin,NS,carcinoma,basal cell carcinoma c.782G>A p.R261Q 2:61496985-61496985 3
26 COSM87040659 TSC2 skin,NS,carcinoma,basal cell carcinoma c.869C>T p.P290L 16:2058767-2058767 3
27 COSM101179498 TSC2 skin,NS,carcinoma,basal cell carcinoma c.1913C>T p.S638F 16:2071897-2071897 3
28 COSM150324396 TSC2 skin,NS,carcinoma,basal cell carcinoma c.869C>T p.P290L 16:2058767-2058767 3
29 COSM101191558 TSC2 skin,NS,carcinoma,basal cell carcinoma c.722C>T p.P241L 16:2058767-2058767 3
30 COSM147706701 TSC2 skin,NS,carcinoma,basal cell carcinoma c.869C>T p.P290L 16:2058767-2058767 3
31 COSM150353664 TSC2 skin,NS,carcinoma,basal cell carcinoma c.2060C>T p.S687F 16:2071897-2071897 3
32 COSM151748023 TSC2 skin,NS,carcinoma,basal cell carcinoma c.679T>A p.C227S 16:2056674-2056674 3
33 COSM150576157 TSC2 skin,NS,carcinoma,basal cell carcinoma c.679T>A p.C227S 16:2056674-2056674 3
34 COSM149802478 TSC2 skin,NS,carcinoma,basal cell carcinoma c.679T>A p.C227S 16:2056674-2056674 3
35 COSM148980439 TSC2 skin,NS,carcinoma,basal cell carcinoma c.2060C>T p.S687F 16:2071897-2071897 3
36 COSM90415129 TSC2 skin,NS,carcinoma,basal cell carcinoma c.869C>T p.P290L 16:2058767-2058767 3
37 COSM149800636 TSC2 skin,NS,carcinoma,basal cell carcinoma c.2060C>T p.S687F 16:2071897-2071897 3
38 COSM148991757 TSC2 skin,NS,carcinoma,basal cell carcinoma c.869C>T p.P290L 16:2058767-2058767 3
39 COSM151753165 TSC2 skin,NS,carcinoma,basal cell carcinoma c.869C>T p.P290L 16:2058767-2058767 3
40 COSM151513825 TSC2 skin,NS,carcinoma,basal cell carcinoma c.679T>A p.C227S 16:2056674-2056674 3
41 COSM151371066 TSC2 skin,NS,carcinoma,basal cell carcinoma c.679T>A p.C227S 16:2056674-2056674 3
42 COSM148982237 TSC2 skin,NS,carcinoma,basal cell carcinoma c.679T>A p.C227S 16:2056674-2056674 3
43 COSM136628294 TSC2 skin,NS,carcinoma,basal cell carcinoma c.902C>T p.P301L 16:2058767-2058767 3
44 COSM110103971 TSC2 skin,NS,carcinoma,basal cell carcinoma c.568T>A p.C190S 16:2056674-2056674 3
45 COSM150583851 TSC2 skin,NS,carcinoma,basal cell carcinoma c.869C>T p.P290L 16:2058767-2058767 3
46 COSM102616914 TSC2 skin,NS,carcinoma,basal cell carcinoma c.2060C>T p.S687F 16:2071897-2071897 3
47 COSM136618116 TSC2 skin,NS,carcinoma,basal cell carcinoma c.712T>A p.C238S 16:2056674-2056674 3
48 COSM110102044 TSC2 skin,NS,carcinoma,basal cell carcinoma c.1949C>T p.S650F 16:2071897-2071897 3
49 COSM150574866 TSC2 skin,NS,carcinoma,basal cell carcinoma c.2060C>T p.S687F 16:2071897-2071897 3
50 COSM102629996 TSC2 skin,NS,carcinoma,basal cell carcinoma c.869C>T p.P290L 16:2058767-2058767 3

Expression for Cystic Basal Cell Carcinoma

Search GEO for disease gene expression data for Cystic Basal Cell Carcinoma.

Pathways for Cystic Basal Cell Carcinoma

Pathways related to Cystic Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.57 KRT20 KRT15 KRT14
2
Show member pathways
11.56 TCHH KRT7 KRT5 KRT20 KRT15 KRT14
3
Show member pathways
11.37 KRT7 KRT5 KRT14
4 11.11 KRT20 KRT15 KRT14

GO Terms for Cystic Basal Cell Carcinoma

Cellular components related to Cystic Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.56 PIP KRT7 KRT5 KRT15 KRT14 ENO2
2 keratin filament GO:0045095 9.33 KRT7 KRT5 KRT14
3 intermediate filament GO:0005882 9.02 KRT7 KRT5 KRT20 KRT15 KRT14

Biological processes related to Cystic Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 epidermis development GO:0008544 9.55 TP63 PTCH1 KRT5 KRT15 KRT14
2 keratinization GO:0031424 9.43 TCHH KRT7 KRT5 KRT20 KRT15 KRT14
3 intermediate filament organization GO:0045109 9.37 TCHH KRT20
4 prostate gland development GO:0030850 9.32 TP63 PTCH1
5 hemidesmosome assembly GO:0031581 9.26 KRT5 KRT14
6 cornification GO:0070268 9.1 TCHH KRT7 KRT5 KRT20 KRT15 KRT14

Molecular functions related to Cystic Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.92 KRT5 KRT20 KRT15 KRT14

Sources for Cystic Basal Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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