Cystic Echinococcosis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Disease Ontology: ¹¹ An echinococcosis that is caused by the larvae of Echinococcus granulosus. Hepatic involvement can result in abdominal pain, a mass in the hepatic area, and biliary duct obstruction. Pulmonary involvement can produce chest pain, cough, and hemoptysis. Rupture of the cysts produce fever, urticaria, eosinophilia, and anaphylactic shock, as well as cyst dissemination. Brain, bone, heart can also be infected.

MalaCards based summary: Cystic Echinococcosis, also known as echinococcus granulosus infection of lung, is related to echinococcosis and alveolar echinococcosis. An important gene associated with Cystic Echinococcosis is MIR26B (MicroRNA 26b), and among its related pathways/superpathways are Innate Lymphoid Cells Differentiation and Th2 Differentiation. The drugs Metronidazole and Albendazole have been mentioned in the context of this disorder. Affiliated tissues include liver, lung and bone, and related phenotypes are eosinophilia and hepatic cysts

Orphanet: ⁵⁸ Hydatidosis or cyst hydatic disease is a cosmopolitan larval cestodosis caused principally by the Echinococcus granulosus tapeworm, the adult form of which parasitises the intestine of dogs. Hydatidosis generally affects large domestic herbivores; humans are dead-end hosts, infected through contact with herding dogs or through ingestion of food contaminated with canine excrement.

Wikipedia: ⁷⁵ Echinococcus granulosus, also called the hydatid worm, hyper tape-worm or dog tapeworm, is a... more...

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Related Diseases for Cystic Echinococcosis

Diseases related to Cystic Echinococcosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 697)

#	Related Disease	Score	Top Affiliating Genes
1	echinococcosis	32.9	MT-CO1 MT-ATP6 IL10
2	alveolar echinococcosis	31.7	RRAGB MT-ND1 MT-CO1 IL4 IL10 CES2
3	fascioliasis	30.7	MT-ND1 MT-CO1 IL4 IL10
4	polycystic echinococcosis	30.5	MT-ND1 MT-CO1 CES1
5	ancylostomiasis	30.5	MT-ND5 MT-ND1 MT-CO1
6	mouth disease	30.3	MIR30A MIR21 IL10 H2AC18
7	enterobiasis	30.2	MT-CO1 IL4
8	toxoplasmosis	30.2	MIR21 IL4 IL10
9	coenurosis	30.2	MT-ND5 MT-ND1 MT-CO1
10	salmonellosis	30.1	IL4 IL10 CD4
11	cysticercosis	30.1	MT-ND5 MT-ND1 MT-CO1 IL4 IL10 CES2
12	dicrocoeliasis	30.1	MT-ND5 MT-ND1 MT-ATP6
13	stomatitis	30.1	IL4 IL10 CD4
14	spinal cord disease	30.0	IL10 H2AC18 CD4
15	ascaris lumbricoides infection	30.0	MT-ND1 IL4 IL10 CD4
16	intestinal schistosomiasis	30.0	MT-CO1 IL4 IL10 CD4
17	visceral leishmaniasis	29.9	IL4 IL10 H2AC18 CD4
18	sparganosis	29.9	MT-ND5 MT-ND1 MT-CO1 MT-ATP6
19	giardiasis	29.9	IL10 H2AC18 CD4
20	actinomycosis	29.9	IL10 CD4
21	trichinosis	29.9	IL4 IL10 CD4
22	t cell deficiency	29.9	IL4 IL10 CD4
23	amebiasis	29.9	IL4 IL10 CD4
24	splenic disease	29.8	IL4 IL10 H2AC18 CD4
25	allergic disease	29.8	MIR21 IL4 IL10 H2AC18 CD4
26	strongyloidiasis	29.7	MT-CO1 IL4 IL10 CD4
27	filarial elephantiasis	29.7	MT-CO1 IL4 IL10 CD4
28	filariasis	29.7	MT-CO1 IL4 IL10 CD4
29	urinary tract infection	29.7	IL10 H2AC18 CD4
30	cryptococcosis	29.7	IL4 IL10 CD4
31	trypanosomiasis	29.7	IL4 IL10 H2AC18 CD4
32	pleural disease	29.7	MIR21 H2AC18 CD4
33	autoimmune lymphoproliferative syndrome	29.6	MT-CO1 MIR21 IL10 CD4
34	parasitic helminthiasis infectious disease	29.6	MT-ND1 MT-CO1 MIR21 IL4 IL10 H2AC18
35	lymphangioma	29.6	IL10 H2AC18 CD4
36	viral infectious disease	29.5	MIR21 IL4 IL10 H2AC18 CD4
37	respiratory failure	29.5	MIR21 IL4 IL10 H2AC18 CD4
38	chagas disease	29.5	IL4 IL10 CD4
39	taeniasis	29.3	MT-ND5 MT-ND1 MT-CO1 IL4 IL10 CES2
40	immune deficiency disease	29.3	MIR30A MIR21 IL4 IL10 H2AC18 CD4
41	lipoprotein quantitative trait locus	29.3	MIR30A MIR21 IL4 IL10 H2AC18 CD4
42	systemic lupus erythematosus	28.9	MT-ATP6 MIR30A MIR21 LSM2 IL4 IL10
43	peripheral nervous system disease	28.3	MT-ND1 MT-ATP6 MIR542 MIR30A MIR21 IL4
44	connective tissue disease	28.3	MIR542 MIR30A MIR26B MIR21 LSM2 IL4
45	toe syndactyly, telecanthus, and anogenital and renal malformations	10.5
46	diarrhea	10.4
47	hypolipoproteinemia	10.4
48	mesocestoidiasis	10.4	MT-ND1 MT-CO1
49	large intestine adenoma	10.4	CES2 CES1
50	echinostomiasis	10.4	MT-ND1 MT-CO1

Graphical network of the top 20 diseases related to Cystic Echinococcosis:

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Symptoms & Phenotypes for Cystic Echinococcosis

Human phenotypes related to Cystic Echinococcosis:

⁵⁸ ³⁰ (show all 44)

#	Description	HPO Frequency	Orphanet Frequency	HPO Source Accession
1	eosinophilia ⁵⁸ ³⁰	Hallmark (90%)	Very frequent (99-80%)	HP:0001880
2	hepatic cysts ⁵⁸ ³⁰	Hallmark (90%)	Very frequent (99-80%)	HP:0001407
3	fatigue ⁵⁸ ³⁰	Frequent (33%)	Frequent (79-30%)	HP:0012378
4	cholestatic liver disease ⁵⁸ ³⁰	Frequent (33%)	Frequent (79-30%)	HP:0002611
5	weight loss ⁵⁸ ³⁰	Frequent (33%)	Frequent (79-30%)	HP:0001824
6	epigastric pain ⁵⁸ ³⁰	Frequent (33%)	Frequent (79-30%)	HP:0410019
7	increased circulating antibody level ³⁰	Frequent (33%)		HP:0010702
8	hepatomegaly ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0002240
9	elevated hepatic transaminase ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0002910
10	hyperbilirubinemia ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0002904
11	biliary tract obstruction ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0005230
12	abdominal symptom ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0011458
13	anaphylactic shock ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0100845
14	abnormality of the diaphragm ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0000775
15	abnormal pulmonary thoracic imaging finding ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0031983
16	multiple pulmonary cysts ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0005948
17	elevated circulating alkaline phosphatase concentration ³⁰	Occasional (7.5%)		HP:0003155
18	elevated gamma-glutamyltransferase level ³⁰	Occasional (7.5%)		HP:0030948
19	asthma ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0002099
20	jaundice ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0000952
21	abnormality of the eye ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0000478
22	abnormality of the vertebral column ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0000925
23	urticaria ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0001025
24	bone cyst ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0012062
25	abnormal heart morphology ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0001627
26	abnormality of the pancreas ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0001732
27	renal cyst ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0000107
28	localized skin lesion ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0011355
29	abnormality of the testis size ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0045058
30	ovarian cyst ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0000138
31	intracranial cystic lesion ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0010576
32	peritoneal abscess ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0100592
33	membranous nephropathy ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0012578
34	splenic cyst ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0030423
35	abnormal subpleural morphology ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0031630
36	invasive parasitic infection ⁵⁸ ³⁰	Very rare (1%)	Very rare (<4-1%)	HP:0031700
37	increased antibody level in blood ⁵⁸		Frequent (79-30%)
38	abnormality of the peritoneum ⁵⁸		Very rare (<4-1%)
39	abnormality of the musculature ⁵⁸		Very rare (<4-1%)
40	abscess ⁵⁸		Occasional (29-5%)
41	elevated alkaline phosphatase ⁵⁸		Occasional (29-5%)
42	elevated gamma-glutamyltransferase activity ⁵⁸		Occasional (29-5%)
43	pulmonary cyst ⁵⁸		Occasional (29-5%)
44	unusual infection ⁵⁸		Occasional (29-5%)

Sources

Drugs & Therapeutics for Cystic Echinococcosis

Drugs for Cystic Echinococcosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Metronidazole

Approved

443-48-1, 69198-10-3

4173

Synonyms:

1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole

1-(2-Hydroxyethyl)-2-methyl-5-nitroimidazole

1-(beta-Ethylol)-2-methyl-5-nitro-3-azapyrrole

1-(beta-Hydroxyethyl)-2-methyl-5-nitroimidazole

1-(beta-Oxyethyl)-2-methyl-5-nitroimidazole

1-(b-Ethylol)-2-methyl-5-nitro-3-azapyrrole

1-(b-Hydroxyethyl)-2-methyl-5-nitroimidazole

1-(b-Oxyethyl)-2-methyl-5-nitroimidazole

1-(Β-ethylol)-2-methyl-5-nitro-3-azapyrrole

1-(Β-hydroxyethyl)-2-methyl-5-nitroimidazole

1-(Β-oxyethyl)-2-methyl-5-nitroimidazole

2 Methyl 5 nitroimidazole 1 ethanol

2-Methyl-1-(2-hydroxyethyl)-5-nitroimidazole

2-Methyl-3-(2-hydroxyethyl)-4-nitroimidazole

2-Methyl-5-nitroimidazole-1-ethanol

ACEA

Acromona

ANABACT

Anagiardil

Apo-Metronidazole

Arilin

Atrivyl

BAY-5360

Bayer 5360

BAYER-5360

Bexon

Clont

Cont

Danizol

Deflamon

Deflamon-Wirkstoff

DRAZIFON

Efloran

ELYZOL

Entizol

Eumin

Flagemona

Flagesol

Flagil

Flagyl

FLAGYL 375

FLAGYL COMPAK

FLAGYL ER

Flagyl I.V.

FLAGYL I.V. RTU IN PLASTIC CONTAINER

FLAGYL-400

FLAGYL-S

Flegyl

Fossyol

Giatricol

Gineflavir

Hydrochloride, metronidazole

Klion

Klont

Meronidal

Methronidazole

Metric

METRIC 21

Metro Cream

Metro I.V.

Metro I.V. In Plastic Container

METRO IV

METROCREAM

Metrodzhil

MetroGel

Metrogel-vaginal

Metrogyl

Metrolag

METROLOTION

METROLYL

METROMIDOL

Metronidaz

Metronidazol

METRONIDAZOLE

Métronidazole

Metronidazole benzoate

Metronidazole Hcl

Metronidazole hydrochloride

Metronidazole in plastic container

Metronidazole monohydrochloride

Metronidazole phosphate

Metronidazole phosphoester

Metronidazolo

Metronidazolum

METROSA

METROTOP

Mexibol

Monagyl

Monasin

Monohydrochloride, metronidazole

Nalox

Neo-Tric

NEUTRATOP

Nida

Nidagel

Noritate

Noritic acid

NORZOL

Novonidazol

NSC-50364

NSC-69587

NUVESSA

Orvagil

Phosphate, metronidazole

Phosphoester, metronidazole

PROTOSTAT

Rathimed

ROSICED

ROZEX

RP-8823

Sanatrichom

Satric

Takimetol

Trichazol

Trichex

Tricho Cordes

Trichocide

Tricho-Gynaedron

Trichomol

Trichopal

Trichopol

Tricocet

Tricom

Tricowas B

Trikacide

Trikamon

Trikojol

Trikozol

Trimeks

Trivazol

Vagilen

Vagimid

VAGINYL

VANDAZOLE

Vertisal

Wagitran

ZADSTAT

ZIDOVAL

ZYOMET

2

Albendazole

Approved, Vet_approved

54965-21-8

2082

3

Mebendazole

Approved, Vet_approved

31431-39-7

4030

4

Benzimidazole

Experimental, Investigational

51-17-2

5798

5

Liver Extracts

6

Antiparasitic Agents

7

Anti-Infective Agents

8

Antimitotic Agents

9

Antiprotozoal Agents

10

Anthelmintics

11

Tubulin Modulators

12

Pharmaceutical Solutions

13

Anesthetics

Interventional clinical trials:

(show all 18)

#	Name	Status	NCT ID	Drugs
1	Multi-metric Quantitative MRI for the Assessment of Hepatic Hydatid Disease- a Pilot Study	Unknown status	NCT03289884
2	Liver Echinococcosis; Jaundice as Initial Presentation, Short and Long Term Results of Surgical Treatment	Unknown status	NCT04271176
3	Laparoscopic Versus Open Conservative Surgery for the Management of Cystic Echinococcosis of the Liver: Prospective, Randomized, and Controlled Clinical Trial of Efficacy and Safety	Completed	NCT01643018
4	Surgical Treatment of Hepatic Hydatidosis in Elderly Patients	Completed	NCT05113550
5	Epidemiology of Human Cystic Hydatid Disease	Completed	NCT00138346
6	VATS Versus Thoracotomy for Pulmonary Hydatid Disease	Completed	NCT04412512
7	The Influence of Two Different Hepatectomy Methods on Transection Speed and Chemokine Release From the Liver	Completed	NCT01785212
8	Outcome After Surgical Treatment of Liver Hydatid Cyst	Completed	NCT05420155
9	Analysis of the Potentially Parasitocidal Effect of a Long Term Chemotherapy With Benzimidazoles in Patients With Inoperable Alveolar Echinococcosis Using PET-CT and EmII/3-10 Serology	Completed	NCT00658294
10	Comprehensive Diagnosis and Treatment of Alveolar Echinococcosis : A Single-center, Longterm Observational Study of 312 Patients in Germany	Completed	NCT02509884
11	Periprosthetic Pathologic Fracture Following Tibial Echinococcosis: A Case Report	Completed	NCT03622346
12	Alveolar Echinococcosis: Parasite Viability and Innovative Markers for Follow-up of Patients Treated With Albendazole - EchinoVISTA Prospective Clinical Study	Completed	NCT02876146	Benzimidazole
13	Management of Liver Hydatid Cysts: A Retrospective Analysis of 293 Cases From Southern Iran	Completed	NCT04363151
14	Splenic Preserving Surgery in Hydatid Spleen	Completed	NCT04890899
15	Intracranial Hydatid Cyst: Series of 8 Cases	Completed	NCT04454268
16	Occult Cysto-biliary Communication and Cyst Fluid Analysis Predicts Post-operative Biliary Fistula and Late Recurrence After Laparoscopic Partial Cystectomy With Omentoplasty in Solitary Primary Adult Liver Hydatid Cyst Disease - A Prospective Multicenter Study.	Completed	NCT05116735
17	Radical Versus Conservative Surgical Treatment of Liver Hydatid Cysts: A Propensity Score Matching Analysis	Completed	NCT04988958
18	Systematic Review of Hypernatremia Following Hydatid Cyst Treatment	Recruiting	NCT05090020

Search NIH Clinical Center for Cystic Echinococcosis

Inferred drug relations via UMLS ⁷¹ / NDF-RT ⁵⁰ :

Albendazole

Sources

Genetic Tests for Cystic Echinococcosis

Genetic tests related to Cystic Echinococcosis:

#	Genetic test	Affiliating Genes
1	Cystic Echinococcosis ²⁸

Sources

Anatomical Context for Cystic Echinococcosis

Organs/tissues related to Cystic Echinococcosis:

MalaCards : Liver, Lung, Bone, Thyroid, Small Intestine, Heart, Brain

Sources

Publications for Cystic Echinococcosis

Articles related to Cystic Echinococcosis:

(show top 50) (show all 10628)

#	Title	Authors	PMID	Year
1	Mediastinal and pericardial hydatidosis: A case report with review of the literature. ⁶²	Rhalem I...Boubbou M	36465165	2023
2	Alterations in Gut Microbiota Profiles of Mice Infected with Echinococcus granulosus sensu lato Microbiota Profiles of Mice Infected with E. granulosus s.l. ⁶²	Zhu M...Zhao W	36048399	2022
3	In vitro efficacy of albendazole-loaded β-cyclodextrin against protoscoleces of Echinococcus granulosus sensu stricto. ⁶²	Bakhtiar NM...Spotin A	36384195	2022
4	Morbidity and Mortality Risk Factors for Lung Hydatidosis Surgery: Over 30 Years' Experience Review. ⁶²	Chaari Z...Frikha I	34808112	2022
5	Anti-echinococcal effects of sumac, Rhus coriaria, in a murine model of cystic echinococcosis: Parasitological and molecular evaluation. ⁶²	Fotoohi S...Harandi MF	36244447	2022
6	A Comparative Evaluation of Four Different Immunoassays in the Diagnosis of Cystic Echinococcosis Using a Crude and Purified Hydatid Cyst Fluid Antigen. ⁶²	Siddartha PV...Swetha CS	36125652	2022
7	'Fight the parasite': raising awareness of cystic echinococcosis in primary school children in endemic countries. ⁶²	Porcu F...Varcasia A	36461072	2022
8	Meta-analysis of the prevalence of bovine cystic echinococcosis in China during decade. ⁶²	Yang XB...Zhao Q	36150257	2022
9	Deciphering the role of miR-71 and let-7 in the fertility of cystic echinococcosis cysts: a preliminary assessment. ⁶²	Azimi A...Fallah M	36266590	2022
10	Isolated peritoneal involvement as a primary manifestation of cystic echinococcosis. ⁶²	Schwarz M...Gschwantler M	36435190	2022
11	A rare case of hydatid cyst of the neck with concurrent pulmonary hydatid disease. ⁶²	Shukla AK...Bhargava JK	36457772	2022
12	Cerebral hydatid cyst in children: A case series of 21 patients and review of literature. ⁶²	Assamadi M...Aniba K	35907445	2022
13	Enhancing respiratory disease diagnosis by bronchoalveolar lavage in Kashmir: an audit of findings. ⁶²	Bhat JI...Qazi IA	35948407	2022
14	A CT-based radiomics nomogram for the differentiation of pulmonary cystic echinococcosis from pulmonary abscess. ⁶²	Li Y...Xing Y	36181541	2022
15	Efficacy of Mesenchymal Stem Cells Therapy in Parasitic Infections: Are Anti-parasitic Drugs Combined with MSCs More Effective? ⁶²	Kian M...Nasri F	36280646	2022
16	Anti-helminthic effects and cellular mechanisms of Astragalus ecbatanus extract against Echinococcus granulosus protoscoleces. ⁶²	Mahmoudvand H...Ghasemian Yadegari J	36457771	2022
17	Multiple intracranial hydatid cysts in posterior fossa in an adult-A case report. ⁶²	Aryal S...Sharma S	36204412	2022
18	[Patient with pulmonary cysts and diagnosis of co-infection with tuberculosis and hydatidosis. Pediatric cases report]. ⁶²	Portillo V...Altcheh J	36374065	2022
19	Is There Any Role of Pulmonary Endarterectomy in Pulmonary Arterial Hydatidosis? ⁶²	Erkilinc A...Yildizeli B	34843694	2022
20	Histopathological and immunological study of rats liver hydatid cysts isolated from human, sheep, goat and cows. ⁶²	Alsaadawi MA...Ali MJ	36457784	2022
21	Aortic aneurysm lesions in Echinococcus infection. A review of cases in literature. ⁶²	Silvestri V...Ngasala B	36257589	2022
22	Spontaneous cutaneous fistula secondary to hepatic hydatidosis. ⁶²	Sogbe M...Luis Del Pozo J	36435381	2022
23	Peritoneal hydatidosis: An exceptional case report. ⁶²	El Bakouri A...Fadil A	36389191	2022
24	Hydatid Disease of the Liver Presenting as Spontaneous Cutaneous Fistula: A case report. ⁶²	Ghabisha S...Eslahi A	36407698	2022
25	The role of the TGF-β/LIF signaling pathway mediated by SMADs during the cyst formation of Echinococcus in young children. ⁶²	Qin SL...Yao HX	36443650	2022
26	Breast hydatid cyst presented as a fluctuant painless lump mimicking galactocele: A case report. ⁶²	Assefa W...Molla B	36356796	2022
27	Genotyping and Identification of Antigen B Gene Polymorphism of Echinococcus granulosus in Edirne, Thrace, and the First Report of Genotype G2 (Tasmanian Sheep Strain) in Turkey ⁶²	Tarladacalisir T...Sakru N	36194122	2022
28	Experimental treatment of cystic echinococcosis: Combination therapy with carvacrol and thymol versus albendazole. ⁶²	Albani C...Celina EM	36435216	2022
29	Surgical Management of Cardiac Cystic Echinococcosis in a Pediatric Patient: A Case Report. ⁶²	Bicer M...Aydemir NA	36420984	2022
30	Comparative analysis of anti-relapse treatment regimens in 110 patients with hepatic and pulmonary hydatid echinococcosis. ⁶²	Galyavin AV	36459040	2022
31	Comment on "Usefulness of the FDG PET/CT in the management of cystic echinococcosis: A pilot study". ⁶²	Manciulli T...Brunetti E	36462531	2022
32	The occurrence of cystic echinococcosis in slaughtered livestock in Jahrom, south of Iran. ⁶²	Shabani M...Armand B	36118047	2022
33	Serum Level of egr-miR-2a-3p as a Potential Diagnostic Biomarker for Cystic Echinococcosis. ⁶²	Karami MF...Dastyar AA	36434379	2022
34	Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE project. ⁶²	Casulli A...Santolamazza F	36427513	2022
35	In Silico Evaluation of the Haplotype Diversity, Phylogenetic Variation and Population Structure of Human E. granulosus sensu stricto (G1 Genotype) Sequences. ⁶²	Selcuk MA...Cao J	36422598	2022
36	Multiple recurrent cystic hydatid disease of abdominal cavity. ⁶²	Yang X...Wang W	35643904	2022
37	Hydatid disease of the brain and spine. ⁶²	Padayachy LC...Ozek MM	36443475	2022
38	Hydatid liver disease with portal vein invasion, cavernous transformation and portal biliopathy. ⁶²	Lopez Grove R...Spina JC	35485257	2022
39	Primary hydatid cyst of the kidney revealed by hydatiduria: A case report. ⁶²	Daoud MF...Ghozzi S	36212223	2022
40	Atypical manifestation of a fistula between a hydatid cyst of a liver and a gallbladder: A case report. ⁶²	Lahfidi A...Saouab R	35965928	2022
41	Primary mesenteric hydatid cyst; a rare manifestation of hydatid disease through a case report and literature review. ⁶²	Adelyar MA...Saadaat R	36115120	2022
42	Biliary cystadenoma: Case report with MRI findings and surgical confirmation. ⁶²	Hoti KD...Choudhary J	35991384	2022
43	François-Amilcar Aran (1817-1861) and the recognition of spinal muscular atrophy. ⁶²	Walusinski O	35513931	2022
44	Protection against cystic echinococcosis in sheep using an Escherichia coli-expressed recombinant antigen (EG95) as a bacterin. ⁶²	Gauci CG...Lightowlers MW	36226566	2022
45	Africa-wide meta-analysis on the prevalence and distribution of human cystic echinococcosis and canine Echinococcus granulosus infections. ⁶²	Karshima SN...Mohammed K	36199100	2022
46	Treatment of protoscoleces with gamma radiation: Potential immunoprotective effect against experimental murine echinococcosis. ⁶²	Hadj Rabia S...Mameri S	36054717	2022
47	Analysis of vaccination strategy against cystic echinococcosis developed in the Province of Río Negro, Argentina: 12 years of work. ⁶²	Labanchi JL...Larrieu E	36054969	2022
48	Prediction of the potential suitable habitat of Echinococcus granulosus, the pathogen of echinococcosis, in the Tibetan Plateau under future climate scenarios. ⁶²	Xu J...Wang R	36269480	2022
49	Cardiac Echinococcosis With Hepatic Involvement in a Child: A Case Report. ⁶²	Akrim Y...El Hakkouni A	36407185	2022
50	Conjugated silver nanoparticles as a diagnostic tool for circulating hydatid antigens. ⁶²	Shakra MY...Shalash IR	36198106	2022

Sources

Genes for Cystic Echinococcosis

Genes related to Cystic Echinococcosis (0 elite genes):

(show all 21)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	MIR26B	MicroRNA 26b	RNA Gene	8.66	DISEASES inferred ¹⁴ ¹⁴
2	CES2	Carboxylesterase 2	Protein Coding	8.55	DISEASES inferred ¹⁴
3	CES1	Carboxylesterase 1	Protein Coding	8.27	DISEASES inferred ¹⁴
4	MT-ND1	Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 1	Protein Coding	8.21	DISEASES inferred ¹⁴
5	MT-CO1	Mitochondrially Encoded Cytochrome C Oxidase I	Protein Coding	7.92	DISEASES inferred ¹⁴
6	MIR21	MicroRNA 21	RNA Gene	7.3	DISEASES inferred ¹⁴ ¹⁴
7	RRAGB	Ras Related GTP Binding B	Protein Coding	6.72	DISEASES inferred ¹⁴
8	H2AC18	H2A Clustered Histone 18	Protein Coding	6.64	DISEASES inferred ¹⁴ ¹⁴
9	REG1A	Regenerating Family Member 1 Alpha	Protein Coding	6.49	DISEASES inferred ¹⁴
10	MT-ND5	Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 5	Protein Coding	6.33	DISEASES inferred ¹⁴
11	IL4	Interleukin 4	Protein Coding	6.14	DISEASES inferred ¹⁴
12	IL10	Interleukin 10	Protein Coding	5.9	DISEASES inferred ¹⁴
13	MIR30A	MicroRNA 30a	RNA Gene	5.73	DISEASES inferred ¹⁴ ¹⁴
14	MIR4659A	MicroRNA 4659a	RNA Gene	5.66	DISEASES inferred ¹⁴
15	LSM2	LSM2 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated	Protein Coding	5.63	DISEASES inferred ¹⁴
16	MT-ATP6	Mitochondrially Encoded ATP Synthase Membrane Subunit 6	Protein Coding	5.41	DISEASES inferred ¹⁴
17	MIR542	MicroRNA 542	RNA Gene	5.39	DISEASES inferred ¹⁴
18	CD4	CD4 Molecule	Protein Coding	5.34	DISEASES inferred ¹⁴
19	WDR11	WD Repeat Domain 11	Protein Coding	5.34	DISEASES inferred ¹⁴
20	EEF1B2	Eukaryotic Translation Elongation Factor 1 Beta 2	Protein Coding	5.31	DISEASES inferred ¹⁴
21	MIR4692	MicroRNA 4692	RNA Gene	5.23	DISEASES inferred ¹⁴

Sources

Variations for Cystic Echinococcosis

Sources

Expression for Cystic Echinococcosis

Search GEO for disease gene expression data for Cystic Echinococcosis.

Sources

Pathways for Cystic Echinococcosis

Pathways related to Cystic Echinococcosis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Innate Lymphoid Cells Differentiation ⁶⁵	11.23	IL4 IL10 CD4
2	Th2 Differentiation ⁶⁵	10.79	IL4 IL10 CD4
3	Selective expression of chemokine receptors during T-cell polarization ⁷⁴	10.5	IL4 CD4
4	Phase I biotransformations, non P450 ⁷⁴ Show member pathways Heroin metabolism ⁷⁴ Methylphenidate Pathway, Pharmacokinetics ⁶⁰	10.3	CES2 CES1
5	Cytokines and inflammatory response ⁷⁴	10.26	IL4 IL10 CD4

Sources

GO Terms for Cystic Echinococcosis

Cellular components related to Cystic Echinococcosis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	respirasome	GO:0070469	8.8	MT-ND5 MT-ND1 MT-CO1

Biological processes related to Cystic Echinococcosis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	type 2 immune response	GO:0042092	9.46	IL4 IL10
2	regulation of isotype switching	GO:0045191	9.26	IL4 IL10
3	electron transport coupled proton transport	GO:0015990	8.92	MT-ND5 MT-CO1

Molecular functions related to Cystic Echinococcosis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	methylumbelliferyl-acetate deacetylase activity	GO:0047374	9.26	CES2 CES1
2	methyl indole-3-acetate esterase activity	GO:0080030	8.62	CES2 CES1

Sources

Sources for Cystic Echinococcosis

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: CYS008 MIFTS: 53	Cystic Echinococcosis Categories: Bone diseases, Cardiovascular diseases, Gastrointestinal diseases, Infectious diseases, Liver diseases, Neuronal diseases, Rare diseases, Respiratory diseases	Data Licensing For inquiries, contact: [email protected]
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Cystic Echinococcosis

Aliases & Classifications for Cystic Echinococcosis

MalaCards integrated aliases for Cystic Echinococcosis:

Characteristics:

Prevelance:

Age Of Onset:

Classifications:

External Ids:

Summaries for Cystic Echinococcosis

Related Diseases for Cystic Echinococcosis

Diseases related to Cystic Echinococcosis via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Cystic Echinococcosis:

Symptoms & Phenotypes for Cystic Echinococcosis

Human phenotypes related to Cystic Echinococcosis:

Drugs & Therapeutics for Cystic Echinococcosis

Drugs for Cystic Echinococcosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Inferred drug relations via UMLS 71 / NDF-RT 50 :

Genetic Tests for Cystic Echinococcosis

Genetic tests related to Cystic Echinococcosis:

Anatomical Context for Cystic Echinococcosis

Organs/tissues related to Cystic Echinococcosis:

Publications for Cystic Echinococcosis

Articles related to Cystic Echinococcosis:

Genes for Cystic Echinococcosis

Genes related to Cystic Echinococcosis (0 elite genes):

Variations for Cystic Echinococcosis

Expression for Cystic Echinococcosis

Pathways for Cystic Echinococcosis

Pathways related to Cystic Echinococcosis according to GeneCards Suite gene sharing:

GO Terms for Cystic Echinococcosis

Cellular components related to Cystic Echinococcosis according to GeneCards Suite gene sharing:

Biological processes related to Cystic Echinococcosis according to GeneCards Suite gene sharing:

Molecular functions related to Cystic Echinococcosis according to GeneCards Suite gene sharing:

Sources for Cystic Echinococcosis

Inferred drug relations via UMLS ⁷¹ / NDF-RT ⁵⁰ :