MCID: CYS005
MIFTS: 58

Cysticercosis

Categories: Cardiovascular diseases, Eye diseases, Gastrointestinal diseases, Infectious diseases, Muscle diseases, Neuronal diseases, Rare diseases, Skin diseases

Aliases & Classifications for Cysticercosis

MalaCards integrated aliases for Cysticercosis:

Name: Cysticercosis 12 53 59 55 3 44 15 73
Neurocysticercosis 12 76 53 55 3 15 73
Submacular Cysticercosis 53 73
Intestinal Taenia Solium Infection 12
Tenia Solium Infectious Disease 12
Pork Tapeworm Infection 12
Tenia Solium Infection 73
Taeniasis 53

Characteristics:

Orphanet epidemiological data:

59
cysticercosis
Inheritance: Not applicable; Age of onset: All ages;

Classifications:

Orphanet: 59  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:10079
ICD10 33 B69 B69.9
ICD9CM 35 123.1
MeSH 44 D003551
NCIt 50 C34520
SNOMED-CT 68 59051007
Orphanet 59 ORPHA1560
ICD10 via Orphanet 34 B69.0 B69.1 B69.8 more
MESH via Orphanet 45 D003551
UMLS via Orphanet 74 C0010678

Summaries for Cysticercosis

NIH Rare Diseases : 53 Cysticercosis is an infection caused by the pork tapeworm, Taenia solium. The condition develops when tapeworm eggs, which can be found in contaminated food, enter the body and form cysticeri (cysts). In most cases, the worms stay in the muscles and do not cause symptoms. However, symptoms may be present when the infection is found in the brain, eyes, heart or spine. Although rare in the United States, cysticercosis is common in many developing countries. Treatment may include medications to kill the parasites and powerful anti-inflammatory medications (steroids) to reduce swelling. In severe cases, surgery may be needed to remove the infected area.

MalaCards based summary : Cysticercosis, also known as neurocysticercosis, is related to echinococcosis and taeniasis. An important gene associated with Cysticercosis is TLR4 (Toll Like Receptor 4), and among its related pathways/superpathways are Innate Immune System and Toll-like Receptor Signaling Pathway. The drugs Albendazole and Omeprazole have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and heart, and related phenotypes are homeostasis/metabolism and immune system

Disease Ontology : 12 A taeniasis that results from ingestion of eggs or larvae of the Taenia solium tapeworm in undercooked pork or fecally contaminated food or water, which subsequently infect the central nervous system, heart, muscles, subcutaneous tissues, and eyes. Neurocysticercosis causes seizures, mental disturbances, focal neurologic deficits and intracerebral lesions.

CDC : 3 Cysticercosis is a parasitic tissue infection caused by larval cysts of the tapeworm Taenia solium. These larval cysts infect brain, muscle, or other tissue, and are a major cause of adult onset seizures in most low-income countries. A person gets cysticercosis by swallowing eggs found in the feces of a person who has an intestinal tapeworm.  People living in the same household with someone who has a tapeworm have a much higher risk of getting cysticercosis than people who don’t.

Wikipedia : 76 Neurocysticercosis /�?nj�?�?ro�?�?sɪsti�?s�?ːr�?ko�?sɪs/ is a specific form of the infectious parasitic... more...

Related Diseases for Cysticercosis

Diseases related to Cysticercosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 247)
# Related Disease Score Top Affiliating Genes
1 echinococcosis 30.9 IL6 MT-CO1 TLR4
2 taeniasis 30.8 MT-CO1 TACSTD2 TKFC
3 anterior uveitis 30.1 IL6 TLR4
4 cystic echinococcosis 30.1 IL6 MT-CO1 TLR4
5 chagas disease 29.9 IL12B IL1B IL6 TLR4
6 toxoplasmosis 29.8 IL1B IL6 TLR4
7 salmonellosis 29.8 IL18 IL1B TLR4
8 lymphadenitis 29.8 IL18 IL1B TLR4
9 leishmaniasis 29.6 IL12B IL1B IL6 TLR4
10 alveolar echinococcosis 29.5 MT-CO1 TLR4
11 coenurosis 29.4 MT-CO1 TACSTD2
12 epilepsy 10.4
13 staphylococcal toxic shock syndrome 10.2 IGHE IL1B
14 prosthetic joint infection 10.2 IL1B TLR4
15 recurrent corneal erosion 10.2 IL1B IL6
16 dementia 10.2
17 bagassosis 10.2 IL1B IL6
18 paraneoplastic syndromes 10.2 IL1B IL6
19 periodontitis, chronic 10.2 IL1B IL6
20 glossitis 10.2 IL1B IL6
21 campylobacteriosis 10.2 IL1B TLR4
22 laryngitis 10.2 IL1B IL6
23 funisitis 10.2 IL1B IL6
24 alcoholic gastritis 10.2 IL18 IL1B
25 suppurative otitis media 10.2 IL1B TLR4
26 euthyroid sick syndrome 10.2 IL1B IL6
27 toxocariasis 10.2
28 acute vascular insufficiency of intestine 10.2 IL1B IL6
29 osteosclerotic myeloma 10.2 IL1B IL6
30 schnitzler syndrome 10.2 IL18 IL1B
31 poems syndrome 10.2 IL1B IL6
32 latex allergy 10.2 IGHE IL18
33 periapical periodontitis 10.2 IL1B IL6
34 central nervous system vasculitis 10.2 IL1B IL6
35 vaginal disease 10.2 IL1B IL6
36 endometrial disease 10.2 IL1B IL6 TLR4
37 pyelitis 10.2 IL6 TLR4
38 bronchiolitis 10.2 IGHE IL6 TLR4
39 middle ear disease 10.2 IL1B IL6 TLR4
40 perinatal necrotizing enterocolitis 10.2 IL1B IL6 TLR4
41 colitis 10.2 IL1B IL6 TLR4
42 q fever 10.2 IL1B IL6 TLR4
43 vaginitis 10.2 IL1B IL6
44 extrinsic cardiomyopathy 10.2 IL1B IL6 TLR4
45 idiopathic neutropenia 10.2 IL1B IL6 TLR4
46 bacterial vaginosis 10.2 IL1B IL6 TLR4
47 pyelonephritis 10.2 IL1B IL6 TLR4
48 typhoid fever 10.2 IL1B IL6 TLR4
49 hyper ige syndrome 10.2 IGHE TLR4
50 rheumatoid arthritis, systemic juvenile 10.2 IL6 MIF

Graphical network of the top 20 diseases related to Cysticercosis:



Diseases related to Cysticercosis

Symptoms & Phenotypes for Cysticercosis

MGI Mouse Phenotypes related to Cysticercosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.85 IL12B IL18 IL1B IL6 MIF MT-CO1
2 immune system MP:0005387 9.61 IL12B IL18 IL1B IL6 MIF MT-CO1
3 neoplasm MP:0002006 9.17 IL12B IL1B IL6 MIF PDCD1LG2 TACSTD2

Drugs & Therapeutics for Cysticercosis

Drugs for Cysticercosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Albendazole Approved, Vet_approved Phase 3,Phase 2,Not Applicable 54965-21-8 2082
2
Omeprazole Approved, Investigational, Vet_approved Phase 3 73590-58-6 4594
3
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3,Phase 2,Not Applicable 1177-87-3
4
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Not Applicable 50-02-2 5743
5
Praziquantel Approved, Investigational, Vet_approved Phase 2, Phase 3,Phase 3,Not Applicable 55268-74-1 4891
6 tannic acid Approved Phase 3
7
Benzocaine Approved, Investigational Phase 3 94-09-7, 1994-09-7 2337
8
Acetazolamide Approved, Vet_approved Phase 2, Phase 3 59-66-5 1986
9 Antiprotozoal Agents Phase 3,Phase 2,Not Applicable
10 Antiparasitic Agents Phase 3,Phase 2,Phase 1,Not Applicable
11 Antimitotic Agents Phase 3,Phase 2,Not Applicable
12 Anti-Infective Agents Phase 3,Phase 2,Phase 1,Not Applicable
13 Anthelmintics Phase 3,Phase 2,Phase 1,Not Applicable
14 Hormone Antagonists Phase 3,Phase 2,Not Applicable
15 BB 1101 Phase 3,Phase 2,Not Applicable
16 Antacids Phase 3
17 Antineoplastic Agents, Hormonal Phase 3,Phase 2,Not Applicable
18 Anti-Inflammatory Agents Phase 3,Phase 2,Not Applicable
19 Hormones Phase 3,Phase 2,Not Applicable
20 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Not Applicable
21 Autonomic Agents Phase 3,Phase 2,Not Applicable
22 Antiemetics Phase 3,Phase 2,Not Applicable
23 Proton Pump Inhibitors Phase 3
24 Peripheral Nervous System Agents Phase 3,Phase 2,Not Applicable
25 Anti-Ulcer Agents Phase 3
26 Gastrointestinal Agents Phase 3,Phase 2,Not Applicable
27 HIV Protease Inhibitors Phase 3,Phase 2
28
protease inhibitors Phase 3,Phase 2
29 glucocorticoids Phase 3,Phase 2,Not Applicable
30 Anticonvulsants Phase 2, Phase 3,Not Applicable
31 Natriuretic Agents Phase 2, Phase 3
32 diuretics Phase 2, Phase 3
33 Carbonic Anhydrase Inhibitors Phase 2, Phase 3
34
Oxfendazole Investigational, Vet_approved Phase 1 53716-50-0 40854
35 Benzimidazole Experimental, Investigational Phase 1 51-17-2
36
Phenytoin Approved, Vet_approved Not Applicable 57-41-0 1775
37
Niclosamide Approved, Investigational, Vet_approved Not Applicable 50-65-7 4477
38
Iodine Approved, Investigational 7553-56-2 807
39 Diuretics, Potassium Sparing Not Applicable
40 Sodium Channel Blockers Not Applicable
41 cadexomer iodine

Interventional clinical trials:

(show all 23)
# Name Status NCT ID Phase Drugs
1 Effects of 2 Different Duration of Albendazole Therapy in Patients With Neurocysticercosis in Brain ≤ 5 Lesions on CT Completed NCT02243644 Phase 3 7 days of albendazole 15 mg/kg/day;28 days of albendazole 15 mg/kg/day
2 A Pilot Study of Neurocysticercosis Treatment Completed NCT00283699 Phase 3 albendazole
3 Corticosteroids to Reduce Frequency of Seizures in Neurocysticercosis Patients Completed NCT00290823 Phase 3 Albendazole;Dexamethasone;Omeprazole
4 Neurocysticercosis: Combined Treatment With Praziquantel (PZQ) and Albendazole (ABZ) Completed NCT00441285 Phase 2, Phase 3 Praziquantel;Albendazole;ABZ Placebo;PZQ Placebo
5 Sub Arachnoid Neurocysticercosis Treatment Outcome (SANTO) Recruiting NCT02947581 Phase 3 Albendazole and praziquantel;Albendazole and praziquantel placebo
6 Treatment of Peri-calcification Edema in Neurocysticercosis (NCC) Recruiting NCT02945527 Phase 2, Phase 3 Acetazolamide;Dexamethasone
7 RCT ALB for SA Cysticercosis Withdrawn NCT00133458 Phase 3 Albendazole
8 PET Imaging of Peripheral Benzodiazepine Receptors in Patients With Neurocysticercosis Using [F-18]FB Completed NCT00527579 Phase 1 [F-18]FBR
9 PET Imaging of Peripheral Benzodiazepine Receptors in Patients With Neurocysticercosis Using [C-11]PBR28 Completed NCT00526916 Phase 1 [C-11]PBR28
10 Phase I Trial Evaluating the Safety and Pharmacokinetics of Oxfendazole Completed NCT02234570 Phase 1 Oxfendazole
11 Single Ascending Dose Safety Study of Oxfendazole Withdrawn NCT01584362 Phase 1 oxfendazole;placebo;oxfendazole;oxfendazole;oxfendazole;oxfendazole;oxfendazole
12 EFECAB: Improving Pig Management to Prevent Epilepsy in Burkina Faso Completed NCT03095339 Not Applicable
13 Brain Tissue Swelling and Seizure Activity in Inactive Cysticercosis Completed NCT00001912
14 Taenia Solium Control Case Study in Zambia Completed NCT01368354 Not Applicable
15 Randomized Study of Albendazole in Patients With Epilepsy Due to Neurocysticercosis Completed NCT00004403 Not Applicable albendazole;dexamethasone;phenytoin
16 Targeted Screening for Taenia Solium Tapeworms Completed NCT01296958 Not Applicable Niclosamide
17 Treatment of Patients With Cysticercosis With Praziquantel or Albendazole Recruiting NCT00001205
18 Taenia Solium Elimination Versus Control: What is the Best Way Forward for Sub-Saharan Africa? Recruiting NCT02612896 Not Applicable Mass drug administration, praziquantel 10mg/kg
19 A Study for the Ocular Toxocariasis Patients With the Pulmonary Toxocariasis, and Ocular Toxocariasis Cohort Recruiting NCT03814837
20 Intestinal Parasites in Inhabitants of Kuyavian-Pomeranian Province in Poland Recruiting NCT03490435
21 Digital Health Promotion in Iringa, Tanzania Not yet recruiting NCT03808597 Not Applicable
22 People Presenting With Neurocysticercosis in North America Terminated NCT02233855
23 Mass Treatment T Solium Community Study Terminated NCT00138359 Not Applicable Niclosamide

Search NIH Clinical Center for Cysticercosis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: cysticercosis

Genetic Tests for Cysticercosis

Anatomical Context for Cysticercosis

MalaCards organs/tissues related to Cysticercosis:

41
Brain, Eye, Heart, Testes, Tongue, Breast, Temporal Lobe

Publications for Cysticercosis

Articles related to Cysticercosis:

(show top 50) (show all 2013)
# Title Authors Year
1
Subretinal cysticercosis with a mobile scolex. ( 29437748 )
2018
2
Seroprevalence of human cysticercosis in JataA-, GoiA!s state, Brazil. ( 29432711 )
2018
3
Transplastomic plants yield a multicomponent vaccine against cysticercosis. ( 29253519 )
2018
4
Development of the multi-epitope chimeric antigen rqTSA-25 from Taenia saginata for serological diagnosis of bovine cysticercosis. ( 29649259 )
2018
5
Disseminated cysticercosis with asymptomatic neurocysticercosis. ( 29893301 )
2018
6
Spinal Intramedullary Cysticercosis: A Summary of Three Cases in Thailand. ( 29720809 )
2018
7
A novel enolase from Taenia solium metacestodes and its evaluation as an immunodiagnostic antigen for porcine cysticercosis. ( 29885292 )
2018
8
Kidney cysticercosis, cysticercosis related kidney disease and cysticercosis in patients with underlying renal problem: A Rare but important tropical renal infection. ( 29970757 )
2018
9
Prevalence of cysticercosis in Estonian pigs and cattle. ( 29230579 )
2018
10
Neurocysticercosis among People Living Near Pigs Heavily Infected with Cysticercosis in Rural Endemic Peru. ( 29210354 )
2018
11
Risk factors associated with taeniosis-cysticercosis in rural farming communities in Gauteng Province, South Africa. ( 29850979 )
2018
12
The epidemiology of porcine Taenia solium cysticercosis in communities of the Central Highlands in Vietnam. ( 29929529 )
2018
13
Analysis of Clinical Profile, Investigation, and Management of Ocular Cysticercosis Seen at a Tertiary Referral Centre. ( 29308965 )
2018
14
Low sensitivity and frequent cross-reactions in commercially available antibody detection ELISA assays for Taenia solium cysticercosis. ( 29160912 )
2018
15
Notes and recommendations for the establishment of control programs for taeniasis and cysticercosis due to Taenia solium in PeruNotes and recommendations for the establishment of control programs for Taeniasis/cysticercosis in Peru. ( 29924259 )
2018
16
Cysticercosis-rare but important. ( 29653666 )
2018
17
Histopathologic aspects of experimental cysticercosis and in situ cytokines profile in C57BL/6 mice. ( 29898081 )
2018
18
Cysticercosis and cytodiagnosis. ( 29193889 )
2018
19
Orbital cysticercosis. ( 29884714 )
2018
20
TAENIA CRASSICEPS CYSTICERCOSIS IN A NILGIRI LANGUR ( SEMNOPITHECUS JOHNII). ( 29900783 )
2018
21
Disseminated cysticercosis presenting as status epilepticus, rhabdomyolysis, and acute kidney injury: An unreported complication. ( 29322996 )
2018
22
High frequency of Taenia pisiformis metacestodes and high sex-associated susceptibility to cysticercosis in naturally infected wild rabbits. ( 29744701 )
2018
23
Economic impact of bovine cysticercosis and taeniosis caused by Taenia saginata in Belgium. ( 29653598 )
2018
24
Seroprevalence and awareness of porcine cysticercosis across different pig production systems in south-central Cambodia. ( 29774294 )
2018
25
Epidemiology and economic impact of bovine cysticercosis and taeniosis caused by Taenia saginata in northeastern Spain (Catalonia). ( 29954438 )
2018
26
Extraocular muscle cysticercosis: never skip steroids. ( 29321202 )
2018
27
A Case of Recurrent Unilateral Periorbital Edema Associated With Subcutaneous Cysticercosis. ( 29800953 )
2018
28
Cysticercosis in Shandong Province, Eastern China. ( 29350149 )
2018
29
Extra-Ocular Cysticercosis Mimicking Orbital Cellulitis. ( 30060802 )
2018
30
Spatial analysis of dengue, cysticercosis and Chagas disease mortality in Ecuador, 2011-2016. ( 30295901 )
2018
31
Molecular identification of cryptic cysticercosis: Taenia ovis krabbei in wild intermediate and domestic definitive hosts. ( 28349853 )
2018
32
Muscular calcified cysticercosis. ( 28363824 )
2018
33
Isolated lingual cysticercosis: A rare case diagnosed on cytology. ( 28994510 )
2018
34
Abattoir surveillance of Sarcocystis spp., Cysticercosis ovis and Echinococcus granulosus in Tasmanian slaughter sheep, 2007-2013. ( 29479682 )
2018
35
Isolated Intramedullary Spinal Cysticercosis: A Case Report with Review of Literature of a Rare Presentation. ( 29492150 )
2018
36
Effectiveness of an education-based control option for human cysticercosis. ( 29530413 )
2018
37
Effectiveness of a community-based educational programme in reducing the cumulative incidence and prevalence of human Taenia solium cysticercosis in Burkina Faso in 2011-14 (EFECAB): a cluster-randomised controlled trial. ( 29530423 )
2018
38
Clinical Profile of Ocular Cysticercosis. ( 29543551 )
2018
39
Orbital apex syndrome secondary to optic nerve cysticercosis. ( 29582260 )
2018
40
Detection of Immunoglobulin G Antibodies to Taenia solium Cysticercosis Antigen Glutathione-S-Transferase-rT24H in Malian Children Using Multiplex Bead Assay. ( 29582729 )
2018
41
One Health-ness Evaluation of Cysticercosis Surveillance Design in Portugal. ( 29594095 )
2018
42
Clinical Cysticercosis epidemiology in Spain based on the hospital discharge database: What's new? ( 29621234 )
2018
43
Experimental porcine cysticercosis using infected beetles with Taenia solium eggs. ( 29626435 )
2018
44
Cerebral cysticercosis. ( 29648655 )
2018
45
Estimating prevalence and diagnostic test characteristics of bovine cysticercosis in Belgium in the absence of a 'gold standard' reference test using a Bayesian approach. ( 29656999 )
2018
46
Prevalence and risk factors for Taenia solium cysticercosis in school-aged children: A school based study in western Sichuan, People's Republic of China. ( 29738570 )
2018
47
Human taeniasis/cysticercosis: a potentially emerging parasitic disease in Europe. ( 29991885 )
2018
48
Evaluation of enzyme-linked immunoelectrotransfer blot for diagnosis of cysticercosis in swine from North India. ( 30008272 )
2018
49
Persistent Taenia solium Cysticercosis In the State of Morelos, Mexico: Human and Porcine Seroprevalence. ( 30019985 )
2018
50
Transmission of porcine cysticercosis in the Portuguesa state of Venezuela. ( 30027489 )
2018

Variations for Cysticercosis

Expression for Cysticercosis

Search GEO for disease gene expression data for Cysticercosis.

Pathways for Cysticercosis

Pathways related to Cysticercosis according to GeneCards Suite gene sharing:

(show all 41)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.89 IGHE IL12B IL18 IL1B IL6 MIF
2
Show member pathways
12.89 IL12B IL18 IL1B IL6 TLR4
3
Show member pathways
12.68 IL12B IL18 IL1B IL6 TLR4
4
Show member pathways
12.62 IL12B IL18 IL1B IL6 TKFC TLR4
5
Show member pathways
12.5 IL12B IL18 IL1B IL6 TLR4
6
Show member pathways
12.48 IL12B IL18 IL1B IL6
7
Show member pathways
12.22 IL1B IL6 MIF TLR4
8
Show member pathways
12.16 IL12B IL18 IL1B IL6
9
Show member pathways
12.13 IL12B IL1B TLR4
10 12.11 IL12B IL18 IL1B IL6 TLR4
11
Show member pathways
12.1 IL18 IL1B IL6
12
Show member pathways
12.09 IL12B IL1B IL6
13
Show member pathways
12.06 IL1B IL6 TLR4
14
Show member pathways
11.97 IL12B IL18 IL1B IL6
15
Show member pathways
11.94 IL1B IL6 TLR4
16 11.93 IL1B IL6 MIF TLR4
17
Show member pathways
11.88 IL12B IL18 IL1B
18
Show member pathways
11.83 IL12B IL18 IL1B IL6 TLR4
19 11.82 IL12B IL1B IL6 TLR4
20 11.78 IL18 IL1B IL6 TLR4
21
Show member pathways
11.77 IL12B IL6 TLR4
22 11.75 IL18 IL1B IL6 TLR4
23 11.68 IL12B IL1B IL6 TLR4
24 11.64 IL18 IL1B IL6
25 11.61 IGHE IL12B IL18 IL1B IL6
26 11.58 IL12B IL1B IL6
27
Show member pathways
11.57 IL1B IL6 MIF
28 11.42 IL12B IL18 IL1B IL6
29 11.4 IL18 IL1B IL6 TLR4
30 11.35 IL12B IL18 IL1B TLR4
31 11.3 IL1B IL6 TLR4
32 11.2 IL12B IL1B IL6
33 11.18 IL1B IL6
34 11.12 IL12B IL18 IL1B IL6
35 11.1 IL12B IL18 IL1B IL6
36 11.07 IL18 IL1B
37 11.01 IL18 IL1B
38 10.76 IL12B IL18 IL1B IL6
39 10.76 IL12B IL18 IL1B IL6 TLR4
40 10.71 MIF TLR4
41 10.46 IL18 IL1B

GO Terms for Cysticercosis

Cellular components related to Cysticercosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 IGHE IL12B IL18 IL1B IL6 MIF
2 external side of plasma membrane GO:0009897 8.92 IGHE IL12B PDCD1LG2 TLR4

Biological processes related to Cysticercosis according to GeneCards Suite gene sharing:

(show all 43)
# Name GO ID Score Top Affiliating Genes
1 innate immune response GO:0045087 9.99 IGHE MIF TKFC TLR4
2 positive regulation of gene expression GO:0010628 9.97 IL18 IL1B IL6 TLR4
3 regulation of signaling receptor activity GO:0010469 9.97 IL12B IL18 IL1B IL6 MIF
4 cell proliferation GO:0008283 9.96 IL12B IL18 MIF TACSTD2
5 inflammatory response GO:0006954 9.93 IL18 IL1B IL6 MIF TLR4
6 immune response GO:0006955 9.93 IGHE IL18 IL1B IL6 PDCD1LG2 TLR4
7 cell surface receptor signaling pathway GO:0007166 9.92 IL12B MIF PDCD1LG2 TACSTD2
8 cytokine-mediated signaling pathway GO:0019221 9.88 IGHE IL12B IL18 IL1B IL6
9 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.83 IL18 IL1B IL6 TLR4
10 defense response to Gram-negative bacterium GO:0050829 9.81 IL12B IL6 TLR4
11 positive regulation of inflammatory response GO:0050729 9.8 IL12B IL18 TLR4
12 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.79 IL12B IL18 IL6
13 positive regulation of interleukin-6 production GO:0032755 9.77 IL1B IL6 TLR4
14 positive regulation of tumor necrosis factor production GO:0032760 9.75 IL12B MIF TLR4
15 positive regulation of T cell proliferation GO:0042102 9.71 IL12B IL1B IL6 PDCD1LG2
16 negative regulation of interferon-gamma production GO:0032689 9.69 PDCD1LG2 TLR4
17 lipopolysaccharide-mediated signaling pathway GO:0031663 9.69 IL18 IL1B TLR4
18 natural killer cell activation GO:0030101 9.68 IL12B IL18
19 positive regulation of interleukin-8 production GO:0032757 9.68 IL1B TLR4
20 positive regulation of activated T cell proliferation GO:0042104 9.68 IL12B IL18
21 negative regulation of neurogenesis GO:0050768 9.68 IL1B IL6
22 positive regulation of interleukin-12 production GO:0032735 9.67 IL12B TLR4
23 positive regulation of interleukin-10 production GO:0032733 9.67 IL12B TLR4
24 positive regulation of chemokine production GO:0032722 9.66 IL6 TLR4
25 positive regulation of glial cell proliferation GO:0060252 9.66 IL1B IL6
26 negative regulation of interleukin-10 production GO:0032693 9.65 IL12B PDCD1LG2
27 positive regulation of interleukin-17 production GO:0032740 9.65 IL12B IL18
28 cellular response to lipopolysaccharide GO:0071222 9.65 IL12B IL1B IL6 PDCD1LG2 TLR4
29 negative regulation of interleukin-17 production GO:0032700 9.64 IL12B TLR4
30 positive regulation of lymphocyte proliferation GO:0050671 9.63 IL12B TLR4
31 interleukin-6 production GO:0032635 9.61 IL18 IL1B
32 positive regulation of natural killer cell proliferation GO:0032819 9.61 IL12B IL18
33 interferon-gamma production GO:0032609 9.61 IL12B IL18 TLR4
34 positive regulation of tissue remodeling GO:0034105 9.6 IL12B IL18
35 positive regulation of T-helper 1 cell cytokine production GO:2000556 9.58 IL18 IL1B
36 positive regulation of NK T cell proliferation GO:0051142 9.56 IL12B IL18
37 T-helper 1 cell cytokine production GO:0035744 9.55 IL12B IL18
38 positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032725 9.54 IL12B IL18 IL1B
39 T-helper 1 type immune response GO:0042088 9.5 IL12B IL18 TLR4
40 interferon-gamma biosynthetic process GO:0042095 9.49 IL12B IL18
41 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.46 IL12B IL18 IL1B TLR4
42 positive regulation of interferon-gamma production GO:0032729 9.26 IL12B IL18 IL1B TLR4
43 positive regulation of neuroinflammatory response GO:0150078 8.8 IL18 IL1B IL6

Molecular functions related to Cysticercosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 IL12B IL18 IL1B IL6 MIF
2 cytokine receptor binding GO:0005126 8.96 IL12B MIF

Sources for Cysticercosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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