MCID: CYS005
MIFTS: 59

Cysticercosis

Categories: Cardiovascular diseases, Eye diseases, Gastrointestinal diseases, Infectious diseases, Muscle diseases, Neuronal diseases, Rare diseases, Skin diseases

Aliases & Classifications for Cysticercosis

MalaCards integrated aliases for Cysticercosis:

Name: Cysticercosis 12 54 60 56 3 45 15 17 74
Neurocysticercosis 12 77 54 56 3 15 74
Submacular Cysticercosis 54 74
Tapeworm Infection: Intestinal Taenia Solum 12
Intestinal Taenia Solium Infection 12
Tenia Solium Infectious Disease 12
Tapeworm Infection: Pork 12
Pork Tapeworm Infection 12
Tenia Solium Infection 74
Taeniasis 54

Characteristics:

Orphanet epidemiological data:

60
cysticercosis
Inheritance: Not applicable; Age of onset: All ages;

Classifications:

Orphanet: 60  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:10079
ICD9CM 36 123.1
MeSH 45 D003551
NCIt 51 C34520
SNOMED-CT 69 59051007
ICD10 34 B69 B69.9
MESH via Orphanet 46 D003551
ICD10 via Orphanet 35 B69.0 B69.1 B69.8 more
UMLS via Orphanet 75 C0010678
Orphanet 60 ORPHA1560

Summaries for Cysticercosis

NIH Rare Diseases : 54 Cysticercosis is an infection caused by the pork tapeworm, Taenia solium. The condition develops when tapeworm eggs, which can be found in contaminated food, enter the body and form cysticeri (cysts). In most cases, the worms stay in the muscles and do not cause symptoms. However, symptoms may be present when the infection is found in the brain, eyes, heart or spine. Although rare in the United States, cysticercosis is common in many developing countries. Treatment may include medications to kill the parasites and powerful anti-inflammatory medications (steroids) to reduce swelling. In severe cases, surgery may be needed to remove the infected area.

MalaCards based summary : Cysticercosis, also known as neurocysticercosis, is related to echinococcosis and taeniasis. An important gene associated with Cysticercosis is TLR4 (Toll Like Receptor 4), and among its related pathways/superpathways are Innate Immune System and Toll-like Receptor Signaling Pathway. The drugs Albendazole and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and heart, and related phenotypes are homeostasis/metabolism and immune system

Disease Ontology : 12 A taeniasis that results from ingestion of eggs or larvae of the Taenia solium tapeworm in undercooked pork or fecally contaminated food or water, which subsequently infect the central nervous system, heart, muscles, subcutaneous tissues, and eyes. Neurocysticercosis causes seizures, mental disturbances, focal neurologic deficits and intracerebral lesions.

CDC : 3 Cysticercosis is a parasitic tissue infection caused by larval cysts of the tapeworm Taenia solium. These larval cysts infect brain, muscle, or other tissue, and are a major cause of adult onset seizures in most low-income countries. A person gets cysticercosis by swallowing eggs found in the feces of a person who has an intestinal tapeworm.  People living in the same household with someone who has a tapeworm have a much higher risk of getting cysticercosis than people who don’t.

Wikipedia : 77 Neurocysticercosis /ˈnjʊəroʊˌsɪstiˌsɜːrˈkoʊsɪs/ is a specific form of the infectious parasitic disease... more...

Related Diseases for Cysticercosis

Diseases related to Cysticercosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 278)
# Related Disease Score Top Affiliating Genes
1 echinococcosis 31.0 IL6 MT-CO1 TLR4
2 taeniasis 30.6 MT-CO1 TACSTD2 TKFC
3 anterior uveitis 30.3 IL6 TLR4
4 ascaris lumbricoides infection 30.3 IL1B IL6
5 cystic echinococcosis 30.2 IL6 MT-CO1 TLR4
6 chagas disease 30.1 IL12B IL1B IL6 TLR4
7 leishmaniasis 30.1 IL12B IL1B TLR4
8 brucellosis 30.0 IL18 IL6 TLR4
9 toxoplasmosis 30.0 IL1B IL6 TLR4
10 salmonellosis 30.0 IL18 IL1B TLR4
11 lymphadenitis 30.0 IL18 IL1B TLR4
12 coenurosis 29.3 MT-CO1 TACSTD2
13 malaria 28.7 IL12B IL18 IL1B IL6 MIF MT-CO1
14 epilepsy 10.5
15 prosthetic joint infection 10.4 IL1B TLR4
16 recurrent corneal erosion 10.4 IL1B IL6
17 staphylococcal toxic shock syndrome 10.4 IGHE IL1B
18 alcoholic gastritis 10.4 IL18 IL1B
19 bagassosis 10.4 IL1B IL6
20 periodontitis, chronic 10.4 IL1B IL6
21 glossitis 10.3 IL1B IL6
22 laryngitis 10.3 IL1B IL6
23 campylobacteriosis 10.3 IL1B TLR4
24 schnitzler syndrome 10.3 IL18 IL1B
25 funisitis 10.3 IL1B IL6
26 euthyroid sick syndrome 10.3 IL1B IL6
27 systemic onset juvenile idiopathic arthritis 10.3 IL18 MIF
28 acute vascular insufficiency of intestine 10.3 IL1B IL6
29 endometrial disease 10.3 IL1B IL6 TLR4
30 middle ear disease 10.3 IL1B IL6 TLR4
31 perinatal necrotizing enterocolitis 10.3 IL1B IL6 TLR4
32 colitis 10.3 IL1B IL6 TLR4
33 q fever 10.3 IL1B IL6 TLR4
34 extrinsic cardiomyopathy 10.3 IL1B IL6 TLR4
35 suppurative otitis media 10.3 IL1B TLR4
36 idiopathic neutropenia 10.3 IL1B IL6 TLR4
37 bacterial vaginosis 10.3 IL1B IL6 TLR4
38 pyelonephritis 10.3 IL1B IL6 TLR4
39 typhoid fever 10.3 IL1B IL6 TLR4
40 bronchiolitis 10.3 IGHE IL6 TLR4
41 uremic pruritus 10.3 IL18 IL1B IL6
42 melioidosis 10.3 IL18 IL6 TLR4
43 aggressive periodontitis 10.3 IL1B IL6 TLR4
44 stachybotrys chartarum 10.3 IL18 IL1B IL6
45 periodontitis 10.3 IL1B IL6 TLR4
46 chorioamnionitis 10.3 IL1B IL6 TLR4
47 hydrocephalus 10.3
48 primary bacterial infectious disease 10.3 IL1B IL6 TLR4
49 osteosclerotic myeloma 10.3 IL1B IL6
50 chlamydia 10.3 IL1B IL6 TLR4

Graphical network of the top 20 diseases related to Cysticercosis:



Diseases related to Cysticercosis

Symptoms & Phenotypes for Cysticercosis

MGI Mouse Phenotypes related to Cysticercosis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.85 IL12B IL18 IL1B IL6 MIF MT-CO1
2 immune system MP:0005387 9.61 IL12B IL18 IL1B IL6 MIF MT-CO1
3 neoplasm MP:0002006 9.17 IL12B IL1B IL6 MIF PDCD1LG2 TACSTD2

Drugs & Therapeutics for Cysticercosis

Drugs for Cysticercosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Albendazole Approved, Vet_approved Phase 3,Phase 2,Not Applicable 54965-21-8 2082
2
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3,Phase 2,Not Applicable 1177-87-3
3
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Not Applicable 50-02-2 5743
4
Omeprazole Approved, Investigational, Vet_approved Phase 3,Phase 2 73590-58-6 4594
5
Praziquantel Approved, Investigational, Vet_approved Phase 2, Phase 3,Phase 3,Not Applicable 55268-74-1 4891
6
tannic acid Approved Phase 3 1401-55-4
7
Benzocaine Approved, Investigational Phase 3 1994-09-7, 94-09-7 2337
8
Acetazolamide Approved, Vet_approved Phase 2, Phase 3 59-66-5 1986
9 Anti-Infective Agents Phase 3,Phase 2,Phase 1,Not Applicable
10 Antiparasitic Agents Phase 3,Phase 2,Phase 1,Not Applicable
11 Antimitotic Agents Phase 3,Phase 2,Not Applicable
12 Antiprotozoal Agents Phase 3,Phase 2,Not Applicable
13 Anthelmintics Phase 3,Phase 2,Phase 1,Not Applicable
14 glucocorticoids Phase 3,Phase 2,Not Applicable
15 HIV Protease Inhibitors Phase 3,Phase 2
16 Autonomic Agents Phase 3,Phase 2,Not Applicable
17 Hormones Phase 3,Phase 2,Not Applicable
18 Antineoplastic Agents, Hormonal Phase 3,Phase 2,Not Applicable
19 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Not Applicable
20 Anti-Inflammatory Agents Phase 3,Phase 2,Not Applicable
21 Antiemetics Phase 3,Phase 2,Not Applicable
22 Gastrointestinal Agents Phase 3,Phase 2,Not Applicable
23
protease inhibitors Phase 3,Phase 2
24 Anti-Ulcer Agents Phase 3
25 Antacids Phase 3
26 BB 1101 Phase 3,Phase 2,Not Applicable
27 Hormone Antagonists Phase 3,Phase 2,Not Applicable
28 Peripheral Nervous System Agents Phase 3,Phase 2,Not Applicable
29 Proton Pump Inhibitors Phase 3
30 Anticonvulsants Phase 2, Phase 3,Not Applicable
31 Carbonic Anhydrase Inhibitors Phase 2, Phase 3
32 diuretics Phase 2, Phase 3
33 Natriuretic Agents Phase 2, Phase 3
34
Oxfendazole Investigational, Vet_approved Phase 1 53716-50-0 40854
35 Benzimidazole Experimental, Investigational Phase 1 51-17-2
36
Phenytoin Approved, Vet_approved Not Applicable 57-41-0 1775
37
Niclosamide Approved, Investigational, Vet_approved Not Applicable 50-65-7 4477
38
Iodine Approved, Investigational 7553-56-2 807
39 Sodium Channel Blockers Not Applicable
40 Diuretics, Potassium Sparing Not Applicable
41 cadexomer iodine

Interventional clinical trials:

(show all 27)
# Name Status NCT ID Phase Drugs
1 Effects of 2 Different Duration of Albendazole Therapy in Patients With Neurocysticercosis in Brain ≤ 5 Lesions on CT Completed NCT02243644 Phase 3 7 days of albendazole 15 mg/kg/day;28 days of albendazole 15 mg/kg/day
2 A Pilot Study of Neurocysticercosis Treatment Completed NCT00283699 Phase 3 albendazole
3 Corticosteroids to Reduce Frequency of Seizures in Neurocysticercosis Patients Completed NCT00290823 Phase 3 Albendazole;Dexamethasone;Omeprazole
4 Neurocysticercosis: Combined Treatment With Praziquantel (PZQ) and Albendazole (ABZ) Completed NCT00441285 Phase 2, Phase 3 Praziquantel;Albendazole;ABZ Placebo;PZQ Placebo
5 Sub Arachnoid Neurocysticercosis Treatment Outcome (SANTO) Recruiting NCT02947581 Phase 3 Albendazole and praziquantel;Albendazole and praziquantel placebo
6 Treatment of Peri-calcification Edema in Neurocysticercosis (NCC) Terminated NCT02945527 Phase 2, Phase 3 Acetazolamide;Dexamethasone
7 RCT ALB for SA Cysticercosis Withdrawn NCT00133458 Phase 3 Albendazole
8 SANCC: Clinical Trial Early Intervention Not yet recruiting NCT03950037 Phase 2 Albendazole
9 PET Imaging of Peripheral Benzodiazepine Receptors in Patients With Neurocysticercosis Using [F-18]FB Completed NCT00527579 Phase 1 [F-18]FBR
10 PET Imaging of Peripheral Benzodiazepine Receptors in Patients With Neurocysticercosis Using [C-11]PBR28 Completed NCT00526916 Phase 1 [C-11]PBR28
11 Phase I Trial Evaluating the Safety and Pharmacokinetics of Oxfendazole Completed NCT02234570 Phase 1 Oxfendazole
12 Single Ascending Dose Safety Study of Oxfendazole Withdrawn NCT01584362 Phase 1 oxfendazole;placebo;oxfendazole;oxfendazole;oxfendazole;oxfendazole;oxfendazole
13 EFECAB: Improving Pig Management to Prevent Epilepsy in Burkina Faso Completed NCT03095339 Not Applicable
14 Brain Tissue Swelling and Seizure Activity in Inactive Cysticercosis Completed NCT00001912
15 Taenia Solium Control Case Study in Zambia Completed NCT01368354 Not Applicable
16 Randomized Study of Albendazole in Patients With Epilepsy Due to Neurocysticercosis Completed NCT00004403 Not Applicable albendazole;dexamethasone;phenytoin
17 Targeted Screening for Taenia Solium Tapeworms Completed NCT01296958 Not Applicable Niclosamide
18 The Burden of (Neuro)Cysticercosis Among People Living With HIV in Rural Tanzania Recruiting NCT03851419
19 Treatment of Patients With Cysticercosis With Praziquantel or Albendazole Recruiting NCT00001205
20 Investigation of Environmental Factors Associated With Transmission of T. Solium in Endemic Villages of Zambia Recruiting NCT03874689
21 Taenia Solium Elimination Versus Control: What is the Best Way Forward for Sub-Saharan Africa? Recruiting NCT02612896 Not Applicable Mass drug administration, praziquantel 10mg/kg
22 A Study for the Ocular Toxocariasis Patients With the Pulmonary Toxocariasis, and Ocular Toxocariasis Cohort Recruiting NCT03814837
23 Intestinal Parasites in Inhabitants of Kuyavian-Pomeranian Province in Poland Recruiting NCT03490435
24 Treatment of Patients With Active Neurocysticercosis in Eastern Africa Not yet recruiting NCT03834337
25 Digital Health Promotion in Iringa, Tanzania Not yet recruiting NCT03808597 Not Applicable
26 People Presenting With Neurocysticercosis in North America Terminated NCT02233855
27 Mass Treatment T Solium Community Study Terminated NCT00138359 Not Applicable Niclosamide

Search NIH Clinical Center for Cysticercosis

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: cysticercosis

Genetic Tests for Cysticercosis

Anatomical Context for Cysticercosis

MalaCards organs/tissues related to Cysticercosis:

42
Brain, Eye, Heart, Testes, Breast, Temporal Lobe, Tongue

Publications for Cysticercosis

Articles related to Cysticercosis:

(show top 50) (show all 3592)
# Title Authors Year
1
Cysticercosis by Taenia pisiformis in Brown Hare (Lepus europaeus) in Northern Italy: Epidemiologic and pathologic features. ( 31080730 )
2019
2
Epidemiology of Taenia saginata taeniosis/cysticercosis: a systematic review of the distribution in central and western Asia and the Caucasus. ( 30999942 )
2019
3
Strategies for tackling Taenia solium taeniosis/cysticercosis: A systematic review and comparison of transmission models, including an assessment of the wider Taeniidae family transmission models. ( 30969966 )
2019
4
Submacular cysticercosis. ( 30957513 )
2019
5
Fine needle aspiration as a diagnostic tool in cysticercosis: a case series. ( 30922414 )
2019
6
Disseminated Cysticercosis. ( 30917261 )
2019
7
Ocular Adnexal Racemose Cysticercosis Masquerading as Dermoid Cyst. ( 30882589 )
2019
8
Characterization of a novel cathepsin L-like protease from Taenia solium metacestodes for the immunodiagnosis of porcine cysticercosis. ( 30878092 )
2019
9
Epidemiology of Taenia saginata taeniosis/cysticercosis: a systematic review of the distribution in the Middle East and North Africa. ( 30876439 )
2019
10
Double inversion recovery in detection of perilesional gliosis in calcific cysticercosis. ( 30860101 )
2019
11
Cysticercosis of the superior oblique muscleof the eye. ( 30859206 )
2019
12
Structural Equation Modeling (SEM) of Cysticercosis in School-Aged Children in Tibetan Rural Farming Areas of Western China: Implications for Intervention Planning. ( 30836642 )
2019
13
How to eliminate taeniasis/cysticercosis: porcine vaccination and human chemotherapy (Part 2). ( 30803437 )
2019
14
Correction to: Epidemiology of taeniosis/cysticercosis in Europe, a systematic review: eastern Europe. ( 30777134 )
2019
15
Fine Needle Aspiration Cytology of Cysticercosis: A Study of 30 Cases. ( 30745734 )
2019
16
Ultrasonographic features of mesenteric cysticercosis in a domestic rabbit (Oryctolagus cuniculus). ( 30740815 )
2019
17
Disseminated cysticercosis in an immunocompetent individual. ( 30729934 )
2019
18
Evaluation of cross-reactivity to Taenia hydatigena and Echinococcus granulosus in the enzyme-linked immunoelectrotransfer blot assay for the diagnosis of porcine cysticercosis. ( 30678700 )
2019
19
Estimating the association between being seropositive for cysticercosis and the prevalence of epilepsy and severe chronic headaches in 60 villages of rural Burkina Faso. ( 30677038 )
2019
20
Spatiotemporal distribution and economic loss associated with bovine cysticercosis and human taeniasis in Ethiopia. ( 30662963 )
2019
21
Performance of a Sandwich Antigen-Detection ELISA for the Diagnosis of Porcine Taenia solium Cysticercosis. ( 30652670 )
2019
22
Cytological diagnosis of cysticercosis: Role of FNAC with On-Site evaluation. ( 30591907 )
2019
23
Epidemiology of taeniosis, cysticercosis and trichinellosis in Iran: A systematic review. ( 30575317 )
2019
24
Clustering of Necropsy-Confirmed Porcine Cysticercosis Surrounding Taenia solium Tapeworm Carriers in Peru. ( 30560769 )
2019
25
A modified lateral flow assay, using serum, for the rapid identification of human and bovine cysticercosis in the absence of false positives. ( 30383274 )
2019
26
Response to letter to editor from Dr Sandeep Moudgil: is the biopsy warranted for cerebral cysticercosis? ( 30376132 )
2019
27
'Cerebral Cysticercosis' in the era of magnets: do we still need to punch the brain first? ( 30376116 )
2019
28
Transmission of porcine cysticercosis in the Portuguesa state of Venezuela. ( 30027489 )
2019
29
Evaluation of enzyme-linked immunoelectrotransfer blot for diagnosis of cysticercosis in swine from North India. ( 30008272 )
2019
30
Orbital apex syndrome secondary to optic nerve cysticercosis. ( 29582260 )
2019
31
Spatial analysis of dengue, cysticercosis and Chagas disease mortality in Ecuador, 2011-2016. ( 30295901 )
2019
32
Neurocysticercosis and epilepsy in sub-Saharan Africa. ( 30170188 )
2019
33
Hydrocephalus in neurocysticercosis: challenges for clinical practice and basic research perspectives. ( 30885859 )
2019
34
Acute Sensorimotor Deficit as a Lone Manifestation of Neurocysticercosis: An Important Differential Diagnosis in Emergency Departments of Developed Countries. ( 30814837 )
2019
35
Endoscopic Management of Fourth Ventricle Neurocysticercosis: Description of the New Technique in a Case Series of 5 Cases and Review of the Literature. ( 30814022 )
2019
36
A Personal Account Regarding the Origin and Evolution of Controversies in the Management of Neurocysticercosis. ( 30761985 )
2019
37
The Association between Calcified Neurocysticercosis and Cognitive Performance: A Case-Control Study Nested to a Population-Based Cohort. ( 30734692 )
2019
38
Albendazole sulfoxide plasma levels and efficacy of antiparasitic treatment in patients with parenchymal neurocysticercosis. ( 30715265 )
2019
39
Conglomerate Ring-Enhancing Lesions are Common in Solitary Neurocysticercosis and do not always Suggest Neurotuberculosis. ( 30692762 )
2019
40
Endoscopic Route for Excision of Intraventricular Neurocysticercosis: Light at the End of the Tunnel. ( 30684716 )
2019
41
Axonal swelling and spheroids in Taenia solium neurocysticercosis. ( 30637855 )
2019
42
Letter in response to Del Brutto, axonal swelling and spheroids in Taenia solium neurocysticercosis. ( 30637848 )
2019
43
Controlling the Host Response in Neurocysticercosis. ( 30608054 )
2019
44
Etanercept to Control Inflammation in the Treatment of Complicated Neurocysticercosis. ( 30608049 )
2019
45
Detection of Taenia solium DNA in the Urine of Neurocysticercosis Patients. ( 30526736 )
2019
46
Factors Associated With Cysticidal Treatment Response in Extraparenchymal Neurocysticercosis. ( 30476351 )
2019
47
Model systems for investigating disease processes in neurocysticercosis. ( 30430955 )
2019
48
Perfusion magnetic resonance imaging in differentiation of neurocysticercosis and tuberculoma. ( 30377746 )
2019
49
Blood-brain barrier disruption and angiogenesis in a rat model for neurocysticercosis. ( 30315659 )
2019
50
Neurocysticercosis: mimics and chameleons. ( 30282762 )
2019

Variations for Cysticercosis

Expression for Cysticercosis

Search GEO for disease gene expression data for Cysticercosis.

Pathways for Cysticercosis

Pathways related to Cysticercosis according to GeneCards Suite gene sharing:

(show all 36)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.91 IGHE IL12B IL18 IL1B IL6 MIF
2
Show member pathways
12.98 IL12B IL18 IL1B IL6 TLR4
3
Show member pathways
12.64 IL12B IL18 IL1B IL6 TKFC TLR4
4
Show member pathways
12.51 IL12B IL18 IL1B IL6 TLR4
5
Show member pathways
12.47 IL12B IL18 IL1B IL6
6
Show member pathways
12.21 IL1B IL6 MIF TLR4
7
Show member pathways
12.15 IL12B IL18 IL1B IL6
8 12.11 IL12B IL18 IL1B IL6 TLR4
9
Show member pathways
12.06 IL1B IL6 TLR4
10
Show member pathways
11.96 IL12B IL18 IL1B IL6
11
Show member pathways
11.93 IL1B IL6 TLR4
12 11.93 IL1B IL6 MIF TLR4
13
Show member pathways
11.86 IL12B IL18 IL1B
14
Show member pathways
11.83 IL12B IL18 IL1B IL6 TLR4
15 11.82 IL12B IL1B IL6 TLR4
16 11.78 IL18 IL1B IL6 TLR4
17
Show member pathways
11.77 IL12B IL6 TLR4
18 11.75 IL18 IL1B IL6 TLR4
19 11.71 IGHE IL12B IL18 IL1B IL6
20 11.66 IL12B IL1B IL6 TLR4
21 11.64 IL18 IL1B IL6
22 11.57 IL12B IL1B IL6
23
Show member pathways
11.57 IL1B IL6 MIF
24 11.42 IL12B IL18 IL1B IL6
25 11.4 IL18 IL1B IL6 TLR4
26 11.35 IL12B IL18 IL1B TLR4
27 11.29 IL1B IL6 TLR4
28 11.2 IL12B IL1B IL6
29 11.12 IL12B IL18 IL1B IL6
30 11.06 IL18 IL1B
31 11.02 IL12B IL18 IL1B IL6
32 11 IL18 IL1B
33 10.76 IL12B IL18 IL1B IL6
34 10.76 IL12B IL18 IL1B IL6 TLR4
35 10.71 MIF TLR4
36 10.45 IL18 IL1B

GO Terms for Cysticercosis

Cellular components related to Cysticercosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.5 DUT IL1B MIF RPLP2 SLC5A2 TACSTD2
2 external side of plasma membrane GO:0009897 8.92 IGHE IL12B PDCD1LG2 TLR4

Biological processes related to Cysticercosis according to GeneCards Suite gene sharing:

(show all 38)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.98 IL12B IL18 IL1B IL6 MIF
2 positive regulation of gene expression GO:0010628 9.97 IL18 IL1B IL6 TLR4
3 cell proliferation GO:0008283 9.96 IL12B IL18 MIF TACSTD2
4 immune response GO:0006955 9.95 IGHE IL18 IL1B IL6 PDCD1LG2 TLR4
5 cell surface receptor signaling pathway GO:0007166 9.93 IL12B MIF PDCD1LG2 TACSTD2
6 inflammatory response GO:0006954 9.93 IL18 IL1B IL6 MIF TLR4
7 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.83 IL18 IL1B IL6 TLR4
8 defense response to Gram-negative bacterium GO:0050829 9.81 IL12B IL6 TLR4
9 positive regulation of inflammatory response GO:0050729 9.8 IL12B IL18 TLR4
10 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.79 IL12B IL18 IL6
11 positive regulation of interleukin-6 production GO:0032755 9.77 IL1B IL6 TLR4
12 cellular response to lipopolysaccharide GO:0071222 9.77 IL12B IL1B IL6 PDCD1LG2 TLR4
13 positive regulation of tumor necrosis factor production GO:0032760 9.74 IL12B MIF TLR4
14 positive regulation of T cell proliferation GO:0042102 9.73 IL12B IL1B IL6 PDCD1LG2
15 lipopolysaccharide-mediated signaling pathway GO:0031663 9.69 IL18 IL1B TLR4
16 negative regulation of neurogenesis GO:0050768 9.68 IL1B IL6
17 positive regulation of interleukin-12 production GO:0032735 9.67 IL12B TLR4
18 positive regulation of interleukin-10 production GO:0032733 9.67 IL12B TLR4
19 positive regulation of chemokine production GO:0032722 9.66 IL6 TLR4
20 positive regulation of glial cell proliferation GO:0060252 9.65 IL1B IL6
21 negative regulation of interleukin-10 production GO:0032693 9.65 IL12B PDCD1LG2
22 positive regulation of interleukin-17 production GO:0032740 9.65 IL12B IL18
23 negative regulation of interleukin-17 production GO:0032700 9.64 IL12B TLR4
24 interferon-gamma production GO:0032609 9.63 IL12B IL18 TLR4
25 positive regulation of lymphocyte proliferation GO:0050671 9.62 IL12B TLR4
26 interleukin-6 production GO:0032635 9.61 IL18 IL1B
27 positive regulation of natural killer cell proliferation GO:0032819 9.61 IL12B IL18
28 positive regulation of tissue remodeling GO:0034105 9.6 IL12B IL18
29 positive regulation of T-helper 1 cell cytokine production GO:2000556 9.58 IL18 IL1B
30 positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032725 9.58 IL12B IL18 IL1B
31 positive regulation of NK T cell proliferation GO:0051142 9.56 IL12B IL18
32 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.56 IL12B IL18 IL1B TLR4
33 T-helper 1 cell cytokine production GO:0035744 9.55 IL12B IL18
34 T-helper 1 type immune response GO:0042088 9.5 IL12B IL18 TLR4
35 interferon-gamma biosynthetic process GO:0042095 9.49 IL12B IL18
36 positive regulation of interferon-gamma production GO:0032729 9.46 IL12B IL18 IL1B TLR4
37 cytokine-mediated signaling pathway GO:0019221 9.43 IGHE IL12B IL18 IL1B IL1RAPL2 IL6
38 positive regulation of neuroinflammatory response GO:0150078 8.8 IL18 IL1B IL6

Molecular functions related to Cysticercosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 IL12B IL18 IL1B IL6 MIF

Sources for Cysticercosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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