MCID: CYS005
MIFTS: 56

Cysticercosis

Categories: Rare diseases, Infectious diseases, Cardiovascular diseases, Neuronal diseases, Eye diseases, Muscle diseases, Gastrointestinal diseases

Aliases & Classifications for Cysticercosis

MalaCards integrated aliases for Cysticercosis:

Name: Cysticercosis 12 53 59 55 3 44 15 73
Neurocysticercosis 12 76 53 55 3 73
Submacular Cysticercosis 53 73
Intestinal Taenia Solium Infection 12
Tenia Solium Infectious Disease 12
Pork Tapeworm Infection 12
Tenia Solium Infection 73
Taeniasis 53

Characteristics:

Orphanet epidemiological data:

59
cysticercosis
Inheritance: Not applicable; Age of onset: All ages;

Classifications:

Orphanet: 59  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:10079
ICD10 33 B69 B69.9
ICD9CM 35 123.1
MeSH 44 D003551
NCIt 50 C34520
Orphanet 59 ORPHA1560
ICD10 via Orphanet 34 B69.0 B69.1 B69.8 more
MESH via Orphanet 45 D003551
UMLS via Orphanet 74 C0010678

Summaries for Cysticercosis

NIH Rare Diseases : 53 Cysticercosis is an infection caused by the pork tapeworm, Taenia solium. The condition develops when tapeworm eggs, which can be found in contaminated food, enter the body and form cysticeri (cysts). In most cases, the worms stay in the muscles and do not cause symptoms. However, symptoms may be present when the infection is found in the brain, eyes, heart or spine. Although rare in the United States, cysticercosis is common in many developing countries. Treatment may include medications to kill the parasites and powerful anti-inflammatory medications (steroids) to reduce swelling. In severe cases, surgery may be needed to remove the infected area.

MalaCards based summary : Cysticercosis, also known as neurocysticercosis, is related to echinococcosis and toxoplasmosis. An important gene associated with Cysticercosis is TLR4 (Toll Like Receptor 4), and among its related pathways/superpathways are Toll-like Receptor Signaling Pathway and Influenza A. The drugs Albendazole and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and heart, and related phenotypes are homeostasis/metabolism and immune system

CDC : 3 Cysticercosis is a parasitic tissue infection caused by larval cysts of the tapeworm Taenia solium. These larval cysts infect brain, muscle, or other tissue, and are a major cause of adult onset seizures in most low-income countries. A person gets cysticercosis by swallowing eggs found in the feces of a person who has an intestinal tapeworm.  People living in the same household with someone who has a tapeworm have a much higher risk of getting cysticercosis than people who don’t.

Disease Ontology : 12 A taeniasis that results from ingestion of eggs or larvae of the Taenia solium tapeworm in undercooked pork or fecally contaminated food or water, which subsequently infect the central nervous system, heart, muscles, subcutaneous tissues, and eyes. Neurocysticercosis causes seizures, mental disturbances, focal neurologic deficits and intracerebral lesions.

Wikipedia : 76 Neurocysticercosis is a specific form of the infectious parasitic disease cysticercosis which is caused... more...

Related Diseases for Cysticercosis

Diseases related to Cysticercosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 165)
# Related Disease Score Top Affiliating Genes
1 echinococcosis 30.1 IL6 MT-CO1 MT-ND1
2 toxoplasmosis 30.1 IL1B IL6 TLR4
3 salmonellosis 30.0 IL18 IL1B TLR4
4 lymphadenitis 29.9 IL18 IL1B TLR4
5 fascioliasis 29.9 IL1B MT-CO1
6 taeniasis 29.7 MT-CO1 MT-ND1 TACSTD2
7 cystic echinococcosis 29.5 MT-CO1 MT-ND1 TLR4
8 chagas disease 29.4 IL12B IL1B IL6 TLR4
9 coenurosis 28.2 MT-CO1 MT-ND1 TACSTD2
10 prosthetic joint infection 10.8 IL1B TLR4
11 staphylococcal toxic shock syndrome 10.8 IGHE IL1B
12 recurrent corneal erosion 10.8 IL1B IL6
13 bagassosis 10.7 IL1B IL6
14 periodontitis, chronic 10.7 IL1B IL6
15 funisitis 10.7 IL1B IL6
16 campylobacteriosis 10.7 IL1B TLR4
17 glossitis 10.7 IL1B IL6
18 euthyroid sick syndrome 10.7 IL1B IL6
19 laryngitis 10.7 IL1B IL6
20 suppurative otitis media 10.7 IL1B TLR4
21 ascaris lumbricoides infection 10.7 IL1B IL6
22 acute vascular insufficiency of intestine 10.7 IL1B IL6
23 systemic onset juvenile idiopathic arthritis 10.6 IL18 IL1B
24 poems syndrome 10.6 IL1B IL6
25 periapical periodontitis 10.6 IL1B IL6
26 schnitzler syndrome 10.6 IL18 IL1B
27 central nervous system vasculitis 10.6 IL1B IL6
28 latex allergy 10.6 IGHE IL18
29 osteosclerotic myeloma 10.6 IL1B IL6
30 vaginal disease 10.5 IL1B IL6
31 bronchiolitis 10.5 IGHE IL6 TLR4
32 endometrial disease 10.5 IL1B IL6 TLR4
33 perinatal necrotizing enterocolitis 10.5 IL1B IL6 TLR4
34 idiopathic neutropenia 10.5 IL1B IL6 TLR4
35 uterine anomalies 10.5 IL1B IL6 TLR4
36 bacterial vaginosis 10.5 IL1B IL6 TLR4
37 pyelonephritis 10.5 IL1B IL6 TLR4
38 typhoid fever 10.5 IL1B IL6 TLR4
39 aggressive periodontitis 10.5 IL1B IL6 TLR4
40 chorioamnionitis 10.5 IL1B IL6 TLR4
41 primary bacterial infectious disease 10.5 IL1B IL6 TLR4
42 chlamydia 10.5 IL1B IL6 TLR4
43 toxic shock syndrome 10.5 IL1B IL6 TLR4
44 intestinal disease 10.5 IL1B IL6 TLR4
45 respiratory system disease 10.5 IL1B IL6 TLR4
46 vaginitis 10.5 IL1B IL6
47 periodontitis 10.5 IL1B IL6 TLR4
48 pertussis 10.4 IL1B IL6 TLR4
49 rheumatoid arthritis, systemic juvenile 10.4 IL6 MIF
50 paracoccidioidomycosis 10.4 IL18 IL6 TLR4

Graphical network of the top 20 diseases related to Cysticercosis:



Diseases related to Cysticercosis

Symptoms & Phenotypes for Cysticercosis

MGI Mouse Phenotypes related to Cysticercosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.85 IL6 MIF MT-CO1 PDCD1LG2 SLC5A2 TACSTD2
2 immune system MP:0005387 9.61 MIF MT-CO1 PDCD1LG2 SLC5A2 TLR4 IL12B
3 neoplasm MP:0002006 9.17 MIF PDCD1LG2 TACSTD2 TLR4 IL12B IL1B

Drugs & Therapeutics for Cysticercosis

Drugs for Cysticercosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 39)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Albendazole Approved, Vet_approved Phase 3,Phase 2,Not Applicable 54965-21-8 2082
2
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Not Applicable 50-02-2 5743
3
Omeprazole Approved, Investigational, Vet_approved Phase 3 73590-58-6 4594
4
Praziquantel Approved, Investigational, Vet_approved Phase 2, Phase 3,Phase 3,Not Applicable 55268-74-1 4891
5
Benzocaine Approved, Investigational Phase 3 1994-09-7, 94-09-7 2337
6
Acetazolamide Approved, Vet_approved Phase 2, Phase 3 59-66-5 1986
7 tannic acid Approved, Nutraceutical Phase 3
8 Anthelmintics Phase 3,Phase 2,Phase 1,Not Applicable
9 Anti-Infective Agents Phase 3,Phase 2,Phase 1,Not Applicable
10 Antimitotic Agents Phase 3,Phase 2,Not Applicable
11 Antiparasitic Agents Phase 3,Phase 2,Phase 1,Not Applicable
12 Antiprotozoal Agents Phase 3,Phase 2,Not Applicable
13 Antacids Phase 3
14 Antiemetics Phase 3,Phase 2,Not Applicable
15 Anti-Inflammatory Agents Phase 3,Phase 2,Not Applicable
16 Antineoplastic Agents, Hormonal Phase 3,Phase 2,Not Applicable
17 Anti-Ulcer Agents Phase 3
18 Autonomic Agents Phase 3,Phase 2,Not Applicable
19 BB 1101 Phase 3,Phase 2,Not Applicable
20 Dexamethasone acetate Phase 3,Phase 2,Not Applicable 1177-87-3
21 Gastrointestinal Agents Phase 3,Phase 2,Not Applicable
22 glucocorticoids Phase 3,Phase 2,Not Applicable
23 HIV Protease Inhibitors Phase 3,Phase 2
24 Hormone Antagonists Phase 3,Phase 2,Not Applicable
25 Hormones Phase 3,Phase 2,Not Applicable
26 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Not Applicable
27 Peripheral Nervous System Agents Phase 3,Phase 2,Not Applicable
28
protease inhibitors Phase 3,Phase 2
29 Proton Pump Inhibitors Phase 3
30 Anticonvulsants Phase 2, Phase 3,Not Applicable
31 Carbonic Anhydrase Inhibitors Phase 2, Phase 3
32 diuretics Phase 2, Phase 3
33 Natriuretic Agents Phase 2, Phase 3
34 Benzimidazole Experimental, Investigational Phase 1 51-17-2
35
Oxfendazole Investigational, Vet_approved Phase 1 53716-50-0 40854
36
Phenytoin Approved, Vet_approved Not Applicable 57-41-0 1775
37
Niclosamide Approved, Investigational, Vet_approved Not Applicable 50-65-7 4477
38 Diuretics, Potassium Sparing Not Applicable
39 Sodium Channel Blockers Not Applicable

Interventional clinical trials:

(show all 21)
# Name Status NCT ID Phase Drugs
1 Effects of 2 Different Duration of Albendazole Therapy in Patients With Neurocysticercosis in Brain ≤ 5 Lesions on CT Completed NCT02243644 Phase 3 7 days of albendazole 15 mg/kg/day;28 days of albendazole 15 mg/kg/day
2 A Pilot Study of Neurocysticercosis Treatment Completed NCT00283699 Phase 3 albendazole
3 Corticosteroids to Reduce Frequency of Seizures in Neurocysticercosis Patients Completed NCT00290823 Phase 3 Albendazole;Dexamethasone;Omeprazole
4 Neurocysticercosis: Combined Treatment With Praziquantel (PZQ) and Albendazole (ABZ) Completed NCT00441285 Phase 2, Phase 3 Praziquantel;Albendazole;ABZ Placebo;PZQ Placebo
5 Sub Arachnoid Neurocysticercosis Treatment Outcome (SANTO) Recruiting NCT02947581 Phase 3 Albendazole and praziquantel;Albendazole and praziquantel placebo
6 Treatment of Peri-calcification Edema in Neurocysticercosis (NCC) Recruiting NCT02945527 Phase 2, Phase 3 Acetazolamide;Dexamethasone
7 RCT ALB for SA Cysticercosis Withdrawn NCT00133458 Phase 3 Albendazole
8 PET Imaging of Peripheral Benzodiazepine Receptors in Patients With Neurocysticercosis Using [F-18]FB Completed NCT00527579 Phase 1 [F-18]FBR
9 PET Imaging of Peripheral Benzodiazepine Receptors in Patients With Neurocysticercosis Using [C-11]PBR28 Completed NCT00526916 Phase 1 [C-11]PBR28
10 Phase I Trial Evaluating the Safety and Pharmacokinetics of Oxfendazole Completed NCT02234570 Phase 1 Oxfendazole
11 Single Ascending Dose Safety Study of Oxfendazole Withdrawn NCT01584362 Phase 1 oxfendazole;placebo;oxfendazole;oxfendazole;oxfendazole;oxfendazole;oxfendazole
12 EFECAB: Improving Pig Management to Prevent Epilepsy in Burkina Faso Completed NCT03095339 Not Applicable
13 Brain Tissue Swelling and Seizure Activity in Inactive Cysticercosis Completed NCT00001912
14 Taenia Solium Control Case Study in Zambia Completed NCT01368354 Not Applicable
15 Randomized Study of Albendazole in Patients With Epilepsy Due to Neurocysticercosis Completed NCT00004403 Not Applicable albendazole;dexamethasone;phenytoin
16 Targeted Screening for Taenia Solium Tapeworms Completed NCT01296958 Not Applicable Niclosamide
17 Treatment of Patients With Cysticercosis With Praziquantel or Albendazole Recruiting NCT00001205
18 Taenia Solium Elimination Versus Control: What is the Best Way Forward for Sub-Saharan Africa? Recruiting NCT02612896 Not Applicable Mass drug administration, praziquantel 10mg/kg
19 Intestinal Parasites in Inhabitants of Kuyavian-Pomeranian Province in Poland Recruiting NCT03490435
20 People Presenting With Neurocysticercosis in North America Terminated NCT02233855
21 Mass Treatment T Solium Community Study Terminated NCT00138359 Not Applicable Niclosamide

Search NIH Clinical Center for Cysticercosis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: cysticercosis

Genetic Tests for Cysticercosis

Anatomical Context for Cysticercosis

MalaCards organs/tissues related to Cysticercosis:

41
Brain, Eye, Heart, Testes, Tongue, Breast, Spinal Cord

Publications for Cysticercosis

Articles related to Cysticercosis:

(show top 50) (show all 770)
# Title Authors Year
1
Subretinal cysticercosis with a mobile scolex. ( 29437748 )
2018
2
Seroprevalence of human cysticercosis in JataA-, GoiA!s state, Brazil. ( 29432711 )
2018
3
Transplastomic plants yield a multicomponent vaccine against cysticercosis. ( 29253519 )
2018
4
Development of the multi-epitope chimeric antigen rqTSA-25 from Taenia saginata for serological diagnosis of bovine cysticercosis. ( 29649259 )
2018
5
Disseminated cysticercosis with asymptomatic neurocysticercosis. ( 29893301 )
2018
6
Spinal Intramedullary Cysticercosis: A Summary of Three Cases in Thailand. ( 29720809 )
2018
7
A novel enolase from Taenia solium metacestodes and its evaluation as an immunodiagnostic antigen for porcine cysticercosis. ( 29885292 )
2018
8
Kidney cysticercosis, cysticercosis related kidney disease and cysticercosis in patients with underlying renal problem: A Rare but important tropical renal infection. ( 29970757 )
2018
9
Prevalence of cysticercosis in Estonian pigs and cattle. ( 29230579 )
2018
10
Neurocysticercosis among People Living Near Pigs Heavily Infected with Cysticercosis in Rural Endemic Peru. ( 29210354 )
2018
11
Risk factors associated with taeniosis-cysticercosis in rural farming communities in Gauteng Province, South Africa. ( 29850979 )
2018
12
The epidemiology of porcine Taenia solium cysticercosis in communities of the Central Highlands in Vietnam. ( 29929529 )
2018
13
Analysis of Clinical Profile, Investigation, and Management of Ocular Cysticercosis Seen at a Tertiary Referral Centre. ( 29308965 )
2018
14
Low sensitivity and frequent cross-reactions in commercially available antibody detection ELISA assays for Taenia solium cysticercosis. ( 29160912 )
2018
15
Notes and recommendations for the establishment of control programs for taeniasis and cysticercosis due to Taenia solium in PeruNotes and recommendations for the establishment of control programs for Taeniasis/cysticercosis in Peru. ( 29924259 )
2018
16
Cysticercosis-rare but important. ( 29653666 )
2018
17
Histopathologic aspects of experimental cysticercosis and in situ cytokines profile in C57BL/6 mice. ( 29898081 )
2018
18
Cysticercosis and cytodiagnosis. ( 29193889 )
2018
19
Orbital cysticercosis. ( 29884714 )
2018
20
TAENIA CRASSICEPS CYSTICERCOSIS IN A NILGIRI LANGUR ( SEMNOPITHECUS JOHNII). ( 29900783 )
2018
21
Disseminated cysticercosis presenting as status epilepticus, rhabdomyolysis, and acute kidney injury: An unreported complication. ( 29322996 )
2018
22
High frequency of Taenia pisiformis metacestodes and high sex-associated susceptibility to cysticercosis in naturally infected wild rabbits. ( 29744701 )
2018
23
Economic impact of bovine cysticercosis and taeniosis caused by Taenia saginata in Belgium. ( 29653598 )
2018
24
Seroprevalence and awareness of porcine cysticercosis across different pig production systems in south-central Cambodia. ( 29774294 )
2018
25
Epidemiology and economic impact of bovine cysticercosis and taeniosis caused by Taenia saginata in northeastern Spain (Catalonia). ( 29954438 )
2018
26
Extraocular muscle cysticercosis: never skip steroids. ( 29321202 )
2018
27
A Case of Recurrent Unilateral Periorbital Edema Associated With Subcutaneous Cysticercosis. ( 29800953 )
2018
28
Cysticercosis in Shandong Province, Eastern China. ( 29350149 )
2018
29
Prevalence and risk factors for Taenia solium cysticercosis in school-aged children: A school based study in western Sichuan, People's Republic of China. ( 29738570 )
2018
30
Estimating prevalence and diagnostic test characteristics of bovine cysticercosis in Belgium in the absence of a 'gold standard' reference test using a Bayesian approach. ( 29656999 )
2018
31
Back Pain and Spinal Cysticercosis. ( 27868401 )
2017
32
Cardiac cysticercosis: A rare cause of myocardial infarction. ( 29157929 )
2017
33
Target product profiles for the diagnosis of Taenia solium taeniasis, neurocysticercosis and porcine cysticercosis. ( 28892472 )
2017
34
Fine-needle aspiration cytology of cysticercosis in submandibular gland. ( 28932037 )
2017
35
Epidemiology of taeniosis/cysticercosis in Europe, a systematic review: Western Europe. ( 28732550 )
2017
36
Mapping the residual incidence of taeniasis and cysticercosis in Colombia, 2009-2013, using geographical information systems: Implications for public health and travel medicine. ( 29288739 )
2017
37
Present status of laboratory diagnosis of human taeniosis/cysticercosis in Europe. ( 28669015 )
2017
38
Primary Intradural Extramedullary Cervical Spinal Cysticercosis. ( 28711534 )
2017
39
Two cases of pulmonary cysticercosis manifesting as pleural effusion: case report and literature review. ( 28932584 )
2017
40
Subcutaneous cysticercosis presenting as cervical swelling: Amazing and unexpected cytological findings. ( 28631659 )
2017
41
Raceomose spinal cysticercosis. ( 28799816 )
2017
42
Mapping occurrence of Taenia solium taeniosis/cysticercosis and areas at risk of porcine cysticercosis in Central America and the Caribbean basin. ( 28923090 )
2017
43
Cysticercosis of the eye. ( 28861361 )
2017
44
Neglected Intraocular Cysticercosis. ( 28910450 )
2017
45
Liquid silicone injection in the chest wall simulating cysticercosis. ( 29160386 )
2017
46
Herd-level spatial cluster analysis of bovine cysticercosis in the state of ParaA-ba, northeastern Brazil. ( 28658414 )
2017
47
Cysticercosis of the eyelid. ( 28851727 )
2017
48
Abdominal Cysticercosis in a Red Fox ( Vulpes vulpes ). ( 27749195 )
2017
49
Development of a health education intervention strategy using an implementation research method to control taeniasis and cysticercosis in Burkina Faso. ( 28569208 )
2017
50
Risk factors, perceptions and practices associated with Taenia solium cysticercosis and its control in the smallholder pig production systems in Uganda: a cross-sectional survey. ( 28049444 )
2017

Variations for Cysticercosis

Expression for Cysticercosis

Search GEO for disease gene expression data for Cysticercosis.

Pathways for Cysticercosis

Pathways related to Cysticercosis according to GeneCards Suite gene sharing:

(show all 37)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.88 IL12B IL18 IL1B IL6 TLR4
2
Show member pathways
12.68 IL12B IL18 IL1B IL6 TLR4
3
Show member pathways
12.65 IL12B IL18 IL1B IL6 TLR4
4
Show member pathways
12.51 IL12B IL18 IL1B IL6
5
Show member pathways
12.47 IL12B IL18 IL1B IL6
6
Show member pathways
12.37 IL12B IL1B TLR4
7
Show member pathways
12.36 IL12B IL18 IL1B IL6 TLR4
8
Show member pathways
12.17 IL1B IL6 MIF TLR4
9
Show member pathways
12.13 IL12B IL18 IL1B IL6 TLR4
10
Show member pathways
12.12 IL12B IL1B TLR4
11
Show member pathways
12.09 IL18 IL1B IL6
12
Show member pathways
12.08 IL12B IL1B IL6
13 12.08 IL12B IL18 IL1B IL6 TLR4
14
Show member pathways
12.05 IL1B IL6 TLR4
15
Show member pathways
11.96 IL12B IL18 IL1B IL6
16 11.93 IL1B IL6 MIF TLR4
17
Show member pathways
11.87 IL12B IL18 IL1B
18 11.81 IL12B IL1B IL6 TLR4
19
Show member pathways
11.77 IL12B IL6 TLR4
20 11.77 IL18 IL1B IL6 TLR4
21 11.73 IL18 IL1B IL6 TLR4
22 11.66 IL12B IL1B IL6 TLR4
23 11.61 IGHE IL12B IL18 IL1B IL6
24 11.58 IL12B IL1B IL6
25
Show member pathways
11.57 IL1B IL6 MIF
26 11.4 IL12B IL18 IL1B IL6
27 11.36 IL18 IL1B IL6 TLR4
28 11.3 IL12B IL18 IL1B TLR4
29 11.29 IL1B IL6 TLR4
30 11.21 IL12B IL1B IL6
31 11.1 IL12B IL18 IL1B IL6
32 11.05 IL18 IL1B
33 10.99 IL18 IL1B
34 10.76 IL12B IL18 IL1B IL6
35 10.76 IL12B IL18 IL1B IL6 TLR4
36 10.71 MIF TLR4
37 10.46 IL18 IL1B

GO Terms for Cysticercosis

Cellular components related to Cysticercosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.17 IGHE IL12B IL18 IL1B IL6 MIF

Biological processes related to Cysticercosis according to GeneCards Suite gene sharing:

(show all 38)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.96 IL12B IL18 IL1B IL6 MIF
2 positive regulation of gene expression GO:0010628 9.95 IL18 IL1B IL6 TLR4
3 cell proliferation GO:0008283 9.94 IL12B IL18 MIF TACSTD2
4 cell surface receptor signaling pathway GO:0007166 9.92 IL12B MIF PDCD1LG2 TACSTD2
5 inflammatory response GO:0006954 9.91 IL18 IL1B IL6 MIF TLR4
6 immune response GO:0006955 9.88 IGHE IL18 IL1B IL6 PDCD1LG2 TLR4
7 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.83 IL1B IL6 TLR4
8 cytokine-mediated signaling pathway GO:0019221 9.83 IGHE IL12B IL18 IL1B IL6
9 defense response to Gram-negative bacterium GO:0050829 9.8 IL12B IL6 TLR4
10 cellular response to lipopolysaccharide GO:0071222 9.8 IL12B IL6 PDCD1LG2 TLR4
11 positive regulation of inflammatory response GO:0050729 9.78 IL12B IL18 TLR4
12 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.76 IL12B IL18 IL6
13 positive regulation of interleukin-6 production GO:0032755 9.74 IL1B IL6 TLR4
14 positive regulation of tumor necrosis factor production GO:0032760 9.7 IL12B MIF TLR4
15 positive regulation of interleukin-8 production GO:0032757 9.68 IL1B TLR4
16 negative regulation of interferon-gamma production GO:0032689 9.67 PDCD1LG2 TLR4
17 positive regulation of activated T cell proliferation GO:0042104 9.67 IL12B IL18
18 positive regulation of interleukin-12 production GO:0032735 9.67 IL12B TLR4
19 positive regulation of interleukin-10 production GO:0032733 9.66 IL12B TLR4
20 natural killer cell activation GO:0030101 9.66 IL12B IL18
21 positive regulation of chemokine production GO:0032722 9.65 IL6 TLR4
22 lipopolysaccharide-mediated signaling pathway GO:0031663 9.65 IL18 IL1B TLR4
23 negative regulation of interleukin-10 production GO:0032693 9.64 IL12B PDCD1LG2
24 positive regulation of interleukin-17 production GO:0032740 9.63 IL12B IL18
25 negative regulation of interleukin-17 production GO:0032700 9.63 IL12B TLR4
26 positive regulation of T cell proliferation GO:0042102 9.62 IL12B IL1B IL6 PDCD1LG2
27 positive regulation of lymphocyte proliferation GO:0050671 9.61 IL12B TLR4
28 interleukin-6 production GO:0032635 9.6 IL18 IL1B
29 positive regulation of natural killer cell proliferation GO:0032819 9.59 IL12B IL18
30 positive regulation of tissue remodeling GO:0034105 9.58 IL12B IL18
31 T-helper 1 cell cytokine production GO:0035744 9.55 IL12B IL18
32 positive regulation of NK T cell proliferation GO:0051142 9.54 IL12B IL18
33 interferon-gamma production GO:0032609 9.54 IL12B IL18 TLR4
34 interferon-gamma biosynthetic process GO:0042095 9.46 IL12B IL18
35 T-helper 1 type immune response GO:0042088 9.43 IL12B IL18 TLR4
36 positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032725 9.33 IL12B IL18 IL1B
37 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.26 IL12B IL18 IL1B TLR4
38 positive regulation of interferon-gamma production GO:0032729 8.92 IL12B IL18 IL1B TLR4

Molecular functions related to Cysticercosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 IL12B IL18 IL1B IL6 MIF
2 cytokine receptor binding GO:0005126 8.96 IL12B MIF

Sources for Cysticercosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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