Aliases & Classifications for Cystitis

MalaCards integrated aliases for Cystitis:

Name: Cystitis 12 55 44 15 63 73
Infective Cystitis 73

Classifications:



External Ids:

Disease Ontology 12 DOID:1679
ICD10 33 N30 N30.9
ICD9CM 35 595 595.9
MeSH 44 D003556
NCIt 50 C26738

Summaries for Cystitis

PubMed Health : 63 About cystitis: Many women know the symptoms of cystitis (a urinary tract infection, or UTI) only too well: frequent trips to the bathroom and a stinging and burning sensation when passing urine. Although these symptoms are often very unpleasant, there are effective treatments. Uncomplicated cystitis usually clears up without any problems.Unfortunately, there is no sure-fire way to reliably prevent cystitis. And a lot of the common strategies women may use in day-to-day life have not yet been scientifically tested.This article is about acute cystitis – a bladder infection often also referred to as a urinary tract infection (UTI). It is not about chronic bladder problems such as interstitial cystitis. It also doesn't include information about treating cystitis in pregnant women.

MalaCards based summary : Cystitis, also known as infective cystitis, is related to acute cystitis and interstitial cystitis. An important gene associated with Cystitis is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Pathways in cancer. The drugs Hyaluronic acid and Acetylcholine have been mentioned in the context of this disorder. Affiliated tissues include prostate, bone and bone marrow, and related phenotypes are behavior/neurological and cardiovascular system

Related Diseases for Cystitis

Diseases in the Cystitis family:

Acute Cystitis Chronic Cystitis

Diseases related to Cystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 344)
# Related Disease Score Top Affiliating Genes
1 acute cystitis 33.8 CRP CXCL8 IL6 UPK1A
2 interstitial cystitis 31.4 CXCL8 EGF HBEGF IL6 KNG1 NGF
3 prostatitis 31.3 CXCL8 IL6 TNF
4 paine syndrome 31.2 NGF TAC1 TRPV1 UPK3A
5 acute pyelonephritis 31.0 CRP CXCL8 IL6
6 bacteriuria 31.0 CXCL8 IL6 TLR4
7 fasciitis 30.3 CXCL8 IL6 TNF
8 gastroenteritis 30.3 CRP CXCL8 IL6 TNF
9 apnea, obstructive sleep 30.3 CRP IL6 TNF
10 urinary tract obstruction 30.3 EGF HBEGF PTGS2 UMOD
11 cholangitis 30.3 CRP IL6 TNF
12 bronchiolitis obliterans 30.2 CXCL8 IL6 TNF
13 meningitis 30.1 CRP CXCL8 IL6 TNF
14 chronic fatigue syndrome 30.1 CXCL8 IL6 TNF
15 vesicoureteral reflux 1 30.0 UMOD UPK1A UPK3A
16 somatoform disorder 30.0 NGF TAC1 TRPV1
17 irritable bowel syndrome 30.0 TAC1 TNF TRPV1
18 ileitis 30.0 IL6 TLR4 TNF
19 pyelonephritis 30.0 CRP CXCL8 IL6 TLR4 TNF UMOD
20 sleep apnea 29.9 CRP CXCL8 IL6 TNF
21 peritonitis 29.9 CRP CXCL8 IL6 TNF
22 wegener granulomatosis 29.9 CRP CXCL8 IL6 TNF
23 bladder disease 29.9 CRP HBEGF IL6 NGF P2RX3 TAC1
24 peptic ulcer disease 29.8 CXCL8 PTGS2 TNF
25 myeloma, multiple 29.8 CRP CXCL8 IL6 TNF
26 bacterial vaginosis 29.7 CXCL8 IL6 TLR4 TNF
27 bronchiolitis 29.7 CXCL8 IL6 TLR4 TNF
28 pneumonia 29.6 CRP CXCL8 IL6 TLR4 TNF
29 rheumatic disease 29.6 CRP PTGS2 TNF
30 arthritis 29.6 CXCL8 IL6 PTGS2 TNF
31 esophagitis 29.5 CXCL8 IL6 PTGS2 TRPV1
32 urinary system disease 29.5 CRP IL6 TNF TRPV1 UMOD
33 pulmonary disease, chronic obstructive 29.4 CRP CXCL8 IL6 TNF TRPV1
34 colitis 29.2 CXCL8 IL6 PTGS2 TLR4 TNF
35 transitional cell carcinoma 28.8 PTGS2 UPK1A UPK3A
36 rheumatoid arthritis 28.7 CRP CXCL8 IL6 PTGS2 TLR4 TNF
37 asthma 28.0 CXCL8 IL6 KNG1 NGF TAC1 TLR4
38 hemorrhagic cystitis 12.4
39 eosinophilic cystitis 12.3
40 cystitis cystica 12.3
41 radiation cystitis 12.2
42 chronic cystitis 12.2
43 chronic interstitial cystitis 12.2
44 acute gonococcal cystitis 12.2
45 glandular cystitis 12.1
46 diphtheritic cystitis 12.0
47 urinary schistosomiasis 11.5
48 urethral syndrome 11.3
49 pelvic lipomatosis 11.2
50 chronic pain 11.2

Comorbidity relations with Cystitis via Phenotypic Disease Network (PDN): (show all 32)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Alzheimer Disease
Bladder Cancer Bladder Neck Obstruction
Bronchitis Chronic Kidney Failure
Chronic Myocardial Ischemia Decubitus Ulcer
Deficiency Anemia Esophagitis
Familial Atrial Fibrillation Generalized Atherosclerosis
Heart Disease Hydronephrosis
Hypertension, Essential Hypothyroidism
Iron Deficiency Anemia Ischemic Heart Disease
Neurogenic Bladder Osteoporosis
Paralytic Ileus Parkinson Disease, Late-Onset
Prostatic Hypertrophy Protein-Energy Malnutrition
Pyelonephritis Radiation Cystitis
Schizophreniform Disorder Transient Cerebral Ischemia
Urethral Stricture Urethritis

Graphical network of the top 20 diseases related to Cystitis:



Diseases related to Cystitis

Symptoms & Phenotypes for Cystitis

MGI Mouse Phenotypes related to Cystitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.06 TAC1 TACR1 HBEGF TLR4 IL6 TNF
2 cardiovascular system MP:0005385 10 TACR1 HBEGF TLR4 IL6 TNF NGF
3 homeostasis/metabolism MP:0005376 9.93 TACR1 HBEGF TLR4 IL6 TNF NGF
4 integument MP:0010771 9.77 EGF TACR1 HBEGF TLR4 IL6 TNF
5 renal/urinary system MP:0005367 9.23 FZD8 TLR4 IL6 TRPV1 UMOD UPK3A

Drugs & Therapeutics for Cystitis

PubMedHealth treatment related to Cystitis: 63

For many women, cystitis is a one-time unpleasant problem. In others, it may keep coming back. Antibiotics have been proven to effectively relieve acute cystitis, and they usually work quickly. There are also some home remedies that may help, like drinking plenty of fluids or applying heat. Herbal products are available too.

Drugs for Cystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 315)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 2,Not Applicable 9004-61-9 53477741
2
Acetylcholine Approved Phase 4,Phase 2,Phase 1,Early Phase 1 51-84-3 187
3
Methenamine Approved, Vet_approved Phase 4,Not Applicable 100-97-0 4101
4
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-18-0, 6055-19-2 2907
5
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
6
Ibuprofen Approved Phase 4 15687-27-1 3672
7
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
8
Oxytocin Approved, Vet_approved Phase 4 50-56-6 439302 53477758
9
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Not Applicable 85721-33-1 2764
10
Nitrofurantoin Approved, Vet_approved Phase 4,Phase 2,Not Applicable 67-20-9 5353830
11
Morphine Approved, Investigational Phase 4 57-27-2 5288826
12
Acetaminophen Approved Phase 4,Phase 2 103-90-2 1983
13
Cycloserine Approved Phase 4 68-41-7 401 6234
14
Amoxicillin Approved, Vet_approved Phase 4,Not Applicable 26787-78-0 33613
15
Levofloxacin Approved, Investigational Phase 4,Phase 3 100986-85-4 149096
16
Ofloxacin Approved Phase 4,Phase 3 82419-36-1 4583
17
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3 53-03-2 5865
18
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
19
Cephalexin Approved, Investigational, Vet_approved Phase 4,Not Applicable 15686-71-2 27447
20
Cefuroxime Approved Phase 4,Not Applicable 55268-75-2 5361202 5479529
21
Metronidazole Approved Phase 4 443-48-1 4173
22
Fosfomycin Approved Phase 4,Not Applicable 23155-02-4 446987
23
Lornoxicam Approved, Investigational Phase 4 70374-39-9 5282204
24
Piroxicam Approved, Investigational Phase 4 36322-90-4 5280452 54676228
25
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
26
gamma-Aminobutyric acid Approved, Investigational Phase 4 56-12-2 119
27
Cefotaxime Approved Phase 4 63527-52-6 456256 5742673
28
Cefoxitin Approved Phase 4 35607-66-0 441199
29
Cilastatin Approved, Investigational Phase 4 82009-34-5 5280454 6435415
30
Imipenem Approved Phase 4 74431-23-5, 64221-86-9 104838
31
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
32
Belladonna Approved, Experimental, Nutraceutical Phase 4
33
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4,Not Applicable 77-92-9 311
34
BCG vaccine Investigational Phase 4,Phase 2
35 Adjuvants, Immunologic Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
36 Protective Agents Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
37 Viscosupplements Phase 4,Phase 2,Not Applicable
38 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
39 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
40 Gentamicins Phase 4,Phase 2
41 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
42 abobotulinumtoxinA Phase 4,Phase 2,Phase 1,Early Phase 1
43 Botulinum Toxins Phase 4,Phase 2,Phase 1,Early Phase 1
44 Botulinum Toxins, Type A Phase 4,Phase 2,Phase 1,Early Phase 1
45 Cholinergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
46 Neuromuscular Agents Phase 4,Phase 2,Phase 1,Early Phase 1
47 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
48 onabotulinumtoxinA Phase 4,Phase 2,Phase 1,Early Phase 1
49 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
50 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 274)
# Name Status NCT ID Phase Drugs
1 Efficacy of Combined Intravesical Therapy With Hyaluronic Acid and Chondroitin Sulphate in the Treatment of Recurrent Cystitis Refractory to Escherichia Coli Extract Unknown status NCT02366676 Phase 4 IALURIL
2 Clinical Efficacy of Changing the InterStim® Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome Unknown status NCT01312259 Phase 4
3 Gentamicin Bladder Instillation Trial Unknown status NCT01884467 Phase 4 Gentamicin;Placebo
4 Functional Electrical Stimulation-Assisted Walking: Reduction of Secondary Complications Due to Spinal Cord Injury Unknown status NCT00201968 Phase 4
5 Botulinum A Toxin in the Treatment of Patients With Painful Bladder Syndrome Unknown status NCT01157507 Phase 4 Intravesical injection of Botulinum A Toxin;Placebo
6 Intravesicular Onabotulinumtoxin A in Interstitial Cystitis Completed NCT02297100 Phase 4 Onabotulinumtoxin A
7 Usefulness of Dexmedetomidine on Post-operative Pain Management in Patients With Interstitial Cystitis Completed NCT01195116 Phase 4 Dexmedetomidine;Normal Saline
8 Ibuprofen Versus Mecillinam for Uncomplicated Cystitis Completed NCT01849926 Phase 4 Ibuprofen;Mecillinam
9 Intranasal Ketorolac Tromethamine (Sprix) for Acute Pain of Interstitial Cystitis Flare of Pain Completed NCT02000401 Phase 4 Ketorolac Tromethamine
10 Intranasal Oxytocin for the Treatment of Pain Associated With Interstitial Cystitis Completed NCT00919802 Phase 4 Oxytocin
11 Botox as a Treatment for Interstitial Cystitis in Women Completed NCT00194610 Phase 4 Botox
12 A Pilot Comparison of Short-course Nitrofurantoin in Females With Uncomplicated Bacterial Cystitis in the Emergency Department Completed NCT01749605 Phase 4 Nitrofurantoin monohydrate/macrocrystals 100 mg BID x 3 days;ciprofloxacin 250 mg BID x 3 days
13 Management of Urinary Tract Infections in Primary Care Facilities. Completed NCT01132131 Phase 4
14 Reduction of Bladder Injection Pain With Belladonna Opiate Suppository Completed NCT02600715 Phase 4 Onabotulinumtoxin A (BoNT);belladonna;Morphine;Placebo;Active B&O suppository of belladonna
15 Treating Urological Chronic Pelvic Pain Syndrome (UCPPS) Pain Completed NCT02385266 Phase 4 D-Cycloserine;Placebo (for D-cycloserine)
16 A Safety and Efficacy Study of Doripenem in Participants With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Urinary Tract Infections Completed NCT00965848 Phase 4 Doripenem
17 Omega-3 Fatty Acids and Postoperative Complications After Colorectal Surgery Completed NCT00488904 Phase 4
18 Interstitial Cystitis: Examination of the Central Autonomic Network Recruiting NCT03008382 Phase 4 Metoprolol Tartrate Oral Tablet;Placebo Oral Tablet
19 Clinical Assessment of Urinary Antiseptics Methenamine and Methylthioninium in Recurrent Cystitis Recruiting NCT03379389 Phase 4 Methenamine + Methylthioninium;Methenamine + Methylthioninium + Acriflavine + Atropa belladona;Antibiotics
20 Management of Sub-Clinical Bacteriuria in Pregnancy Recruiting NCT03275623 Phase 4 Antibiotic
21 Chronic Pain Risk Associated With Menstrual Period Pain Recruiting NCT02214550 Phase 4 microgestin 1/20
22 Prophylaxis of Ileostomy Closure Site Hernia by Placing Mesh Recruiting NCT02226887 Phase 4
23 Parenteral Antibiotics Compared to Combination of Oral and Parenteral Antibiotics in Colorectal Surgery Prophylaxis Recruiting NCT02505581 Phase 4 Extra dosage - cefuroxime (750mg) I.V;Cefuroxime 750mg oral;Metronidazole 250mg oral;Metronidazole 1,5gr Intravenous;Cefuroxime 1g Intravenous
24 Study Comparing Nitrofurantoin to Fosfomycin for Acute Urinary Tract Infection in Women Active, not recruiting NCT01966653 Phase 4 nitrofurantoin;fosfomycin
25 Solifenacin, Levofloxacin or Lornoxicam, Which Is Ideal for Management of Intravesical Instillation BCG Side Effects? Active, not recruiting NCT03038321 Phase 4 sofenacin;Tavanic;Xefo
26 Extended Follow-up of Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy Active, not recruiting NCT03218852 Phase 4 prednisone and cyclophosphamide;prednisone alone
27 Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy Active, not recruiting NCT01758120 Phase 4 prednisone plus cyclophosphamide;Prednisone alone
28 Effectiveness and Safety Study of Pentosan Polysulfate Sodium for the Treatment of Interstitial Cystitis Terminated NCT00086684 Phase 4 Pentosan polysulfate sodium 100 mg;Placebo;Pentosan polysulfate sodium 100 mg
29 Efficacy of Gralise® for Chronic Pelvic Pain Terminated NCT01678911 Phase 4 Gralise
30 Evaluation of the Non-inferiority of Cefoxitin Versus Imipenem/Cilastatin in the Treatment of Urinary Tract Infections Caused by ESBL-producing Escherichia Coli Terminated NCT02474706 Phase 4 Cefoxitin;imipenem
31 The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study Terminated NCT00164099 Phase 4 Synbiotic 2000
32 Trial of Viagra' in Men With Chronic Pelvic Pain Syndrome Type III Terminated NCT00194597 Phase 4 Viagra (sildenafil citrate)
33 Chronic Bladder Pain Syndrome in Women: Can Doxycycline Help? A Prospective Study Terminated NCT01879930 Phase 4 doxycycline;placebo
34 Nitrofurantoin Macrocrystals 3 Days Versus 7 Days in the Treatment of Women With Uncomplicated Cystitis Withdrawn NCT00361998 Phase 4 NITROFURANTOIN MACROCRYSTALS
35 Acupuncture for the Treatment of Interstitial Cystitis (IC) Symptoms Unknown status NCT00094874 Phase 3
36 Comparison of Cy-Atg vs Flu-Atg for the Conditioning Therapy in Allo-HCT for Adult Aplastic Anemia Unknown status NCT01145976 Phase 3 Cy-ATG;Flu-ATG
37 Efficacy Study of Adalimumab to Treat Interstitial Cystitis Completed NCT01295814 Phase 3 Adalimumab
38 Pilot Study Evaluating the Efficacy of Certolizumab Pegol for Interstitial Cystitis Completed NCT02497976 Phase 3 Placebo
39 Omalizumab in Interstitial Cystitis/Bladder Pain Syndrome Completed NCT01294878 Phase 3 omalizumab
40 URACYST® For the Treatment of GAG Deficient Interstitial Cystitis Completed NCT00150488 Phase 2, Phase 3
41 Efficacy and Safety of Cefditoren Pivoxil Versus Ciprofloxacin in Acute Uncomplicated Cystitis Completed NCT00598403 Phase 3 cefditoren pivoxil;Ciprofloxacin
42 Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS) Completed NCT00124306 Phase 3 Amitriptyline
43 A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression Completed NCT02497287 Phase 3 Esketamine (Intranasal Spray);Duloxetine (Oral Antidepressant);Escitalopram (Oral Antidepressant);Sertraline (Oral Antidepressant);Venlafaxine Extended Release (XR) (Oral Antidepressant)
44 D Mannose in Recurrent Urinary Tract Infections Completed NCT01808755 Phase 3 trimethoprim/sulfamethoxazole
45 A Comparison of the Effectiveness and Safety of Levofloxacin to That of Ciprofloxacin in Treating Complicated Urinary Tract Infection and Acute Pyelonephritis. Completed NCT00210886 Phase 3 levofloxacin
46 Letermovir (MK-8228) Versus Placebo in the Prevention of Clinically-Significant Cytomegalovirus (CMV) Infection in Adult, CMV-Seropositive Allogeneic Hematopoietic Stem Cell Transplant Recipients (MK-8228-001) Completed NCT02137772 Phase 3 Letermovir;Placebo
47 Rituximab for the Treatment of Wegener's Granulomatosis and Microscopic Polyangiitis Completed NCT00104299 Phase 2, Phase 3 Rituximab plus cyclophosphamide placebo (rituximab group);Cyclophosphamide plus rituximab placebo (control group);Azathioprine;Methylprednisolone (or other glucocorticoid);Prednisone
48 A Pilot Study of the Effects of Mirabegron on Symptoms in Patients With Interstitial Cystitis Recruiting NCT02787083 Phase 3 Mirabegron;Placebo
49 Radiation Induced Cystitis Treated With Hyperbaric Oxygen - A Randomized Controlled Trial Recruiting NCT01659723 Phase 2, Phase 3 Hyperbaric Oxygen
50 Cyclophosphamide for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Recruiting NCT02460588 Phase 3 Cyclophosphamide;Placebo;Corticosteroid (prednisolone)

Search NIH Clinical Center for Cystitis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: cystitis

Genetic Tests for Cystitis

Anatomical Context for Cystitis

MalaCards organs/tissues related to Cystitis:

41
Prostate, Bone, Bone Marrow, Spinal Cord, Brain, Testes, T Cells

Publications for Cystitis

Articles related to Cystitis:

(show top 50) (show all 1415)
# Title Authors Year
1
Photoselective Vaporisation of the Bladder for the Management of Radiation Cystitis - Technique and Initial Outcomes. ( 29777786 )
2018
2
Struvite urolithiasis with eosinophilic polypoid cystitis in a shih tzu dog. ( 29386681 )
2018
3
Scoping Review and Meta-analysis of Hyperbaric Oxygen Therapy for Radiation-Induced Hemorrhagic Cystitis. ( 29654564 )
2018
4
Prevention of Cystitis: Travelling between the Imaginary and Reality. ( 29925071 )
2018
5
Downregulation of tight junction protein zonula occludens-2 and urothelium damage in a cyclophosphamide-induced mouse model of cystitis. ( 29880173 )
2018
6
BK Viremia as a Predictor of Hemorrhagic Cystitis in Adults During the First 100 Days After Allogeneic Hematopoietic Stem Cell Transplantation. ( 29880378 )
2018
7
Validation of the Spanish version of the Bladder Pain/Interstitial Cystitis-Symptom Score (BPIC-SS) questionnaire. A useful tool for the diagnosis of bladder pain syndrome. ( 29650471 )
2018
8
Safety and Feasibility of Intravesical Instillation of Botulinum Toxin-A in Hydrogel-based Slow-release Delivery System in Patients With Interstitial Cystitis-Bladder Pain Syndrome: A Pilot Study. ( 29307733 )
2018
9
Alleviation of Cyclophosphamide-induced Hemorrhagic Cystitis by Dietary Pomegranate: A Comparative Experimental Study With Mesna. ( 29734214 )
2018
10
Severe BK polyomavirus-induced hemorrhagic cystitis in a kidney transplant recipient with the absence of renal allograft involvement. ( 29143415 )
2018
11
Urinary and psychological outcomes in women with interstitial cystitis/bladder pain syndrome following hyaluronic acid treatment. ( 29880165 )
2018
12
Crosstalk between the immune system and neural pathways in interstitial cystitis/bladder pain syndrome. ( 29906407 )
2018
13
The efficacy of botulinum toxin A and sacral neuromodulation in the management of interstitial cystitis (IC)/bladder pain syndrome (BPS), what do we know? ICI-RS 2017 think thank, Bristol. ( 29363792 )
2018
14
Emphysematous Cystitis in a Non-Diabetic Male. ( 29848437 )
2018
15
Recurrent bacterial symptomatic cystitis: A pilot study on a new natural option for treatment. ( 29974728 )
2018
16
Hyperbaric oxygen as a treatment modality in cyclophosphamide-induced hemorrhagic cystitis. ( 29569791 )
2018
17
Comparison of inflammatory urine markers in patients with interstitial cystitis and overactive bladder. ( 29372285 )
2018
18
Animal Model of Interstitial Cystitis/Bladder Pain Syndrome. ( 29385782 )
2018
19
Differences in Urodynamic Parameters According to the Presence of a Hunner Lesion in Women With Interstitial Cystitis/Bladder Pain Syndrome. ( 29385787 )
2018
20
Serum Cytokine Profiling in Cats with Acute Idiopathic Cystitis. ( 29356123 )
2018
21
Animal Modelling of Interstitial Cystitis/Bladder Pain Syndrome. ( 29385788 )
2018
22
Downregulation of WNT11 is associated with bladder tissue fibrosis in patients with interstitial cystitis/bladder pain syndrome without Hunner lesion. ( 29955137 )
2018
23
Hemorrhagic cystitis associated with gefitinib treatment: a case report. ( 29958970 )
2018
24
Comparative study of efficacy and safety between bladder body and trigonal intravesical onabotulinumtoxina injection in the treatment of interstitial cystitis refractory to conventional treatment-A prospective, randomized, clinical trial. ( 29331031 )
2018
25
Placenta-Derived Decidua Stromal Cells for Hemorrhagic Cystitis after Stem Cell Transplantation. ( 29408819 )
2018
26
Comparison of intravenous or intravesical cidofovir in the treatment of BK polyomavirus-associated hemorrhagic cystitis following adult allogeneic stem cell transplantation-A systematic review. ( 29797613 )
2018
27
Advances in intravesical therapy for bladder pain syndrome (BPS)/interstitial cystitis (IC). ( 29341502 )
2018
28
Emphysematous pyelonephritis and cystitis: A case report and literature review. ( 29916283 )
2018
29
Improving the utility of clinical phenotyping in interstitial cystitis/painful bladder syndrome: from UPOINT to INPUT. ( 29680002 )
2018
30
Surgical Treatment of Eosinophilic Cystitis in Adults: A Report of Two Cases and a Literature Review. ( 29554647 )
2018
31
Endometriosis increased the risk of bladder pain syndrome/interstitial cystitis: A population-based study. ( 29318645 )
2018
32
Epstein-Barr Virus Presence as a Potential Etiology of Persistent Bladder Inflammation in Human Interstitial Cystitis/Bladder Pain Syndrome. ( 29653163 )
2018
33
Intravesicular cidofovir for BK hemorrhagic cystitis in pediatric patients after hematopoietic stem cell transplant. ( 29388318 )
2018
34
Treatment of late-onset hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation: the role of corticosteroids. ( 29532160 )
2018
35
FDA Brudac 2018 Criteria for Interstitial Cystitis/Bladder Pain Syndrome Clinical Trials: Future Direction for IC/BPS Research. ( 29452126 )
2018
36
High incidence of BK virus-associated hemorrhagic cystitis in children after second or third allogeneic hematopoietic stem cell transplantation. ( 29654658 )
2018
37
An evaluation of the pharmacotherapy for interstitial cystitis. ( 29972328 )
2018
38
Management of interstitial cystitis/bladder pain syndrome. ( 29875041 )
2018
39
Hemorrhagic cystitis after hematopoietic stem cell transplantation: A challenge for the pediatric urologist. ( 29776868 )
2018
40
Repetitive transcranial magnetic stimulation for chronic neuropathic pain in patients with bladder pain syndrome/interstitial cystitis. ( 29797500 )
2018
41
Female Veterans With Diagnoses of Both Chronic Pelvic Pain and Overactive Bladder; How Do They Compare to Women Diagnosed With Interstitial Cystitis? ( 29746393 )
2018
42
Bladder pain syndrome/interstitial cystitis is associated with asthma: A case-control study. ( 29441652 )
2018
43
Distribution of mast cell subtypes in interstitial cystitis: implications for novel diagnostic and therapeutic strategies? ( 29764932 )
2018
44
Equine idiopathic hemorrhagic cystitis: Clinical features and comparison with bladder neoplasia. ( 29604121 )
2018
45
Successful medical management of pseudomembranous cystitis in three cats with lower urinary tract obstruction. ( 29226304 )
2018
46
Efficacy of Cidofovir in Treatment of BK Virus-Induced Hemorrhagic Cystitis in Allogeneic Hematopoietic Cell Transplant Recipients. ( 29679772 )
2018
47
Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis. ( 29613835 )
2018
48
IL-33 mast cell axis is central in LL-37 induced bladder inflammation and pain in a murine interstitial cystitis model. ( 29784508 )
2018
49
Is cytomegalovirus a risk factor for haemorrhagic cystitis in allogeneic haematopoietic stem cell transplantation recipients? ( 29972137 )
2018
50
Inflammation and Tissue Remodeling in the Bladder and Urethra in Feline Interstitial Cystitis. ( 29706873 )
2018

Variations for Cystitis

Expression for Cystitis

Search GEO for disease gene expression data for Cystitis.

Pathways for Cystitis

Pathways related to Cystitis according to GeneCards Suite gene sharing:

(show all 37)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.89 EGF FZD8 IL6 NGF PTGS2 TLR4
2 12.79 CXCL8 EGF FZD8 IL6 PTGS2
3
Show member pathways
12.75 CXCL8 IL6 TACR1 TLR4 TNF
4
Show member pathways
12.65 EGF IL6 NGF TLR4 TNF
5
Show member pathways
12.51 CXCL8 IL6 PTGS2 TLR4 TNF
6
Show member pathways
12.29 CRP IL6 PTGS2 TNF
7
Show member pathways
12.28 CXCL8 IL6 PTGS2 TNF
8 12.25 FZD8 HBEGF TLR4 TNF
9
Show member pathways
12.21 CXCL8 IL6 TLR4 TNF
10
Show member pathways
12.17 CXCL8 IL6 PTGS2 TNF
11
Show member pathways
12.17 CXCL8 IL6 PTGS2 TLR4 TNF
12
Show member pathways
12.12 CXCL8 IL6 TLR4 TNF
13
Show member pathways
12.05 EGF FZD8 HBEGF IL6
14 11.95 EGF FZD8 IL6 PTGS2 TLR4 TNF
15 11.93 CXCL8 IL6 PTGS2 TNF
16 11.85 CXCL8 IL6 NGF TAC1 TACR1 TNF
17 11.84 CXCL8 IL6 TLR4 TNF
18 11.83 CXCL8 PTGS2 TLR4 TNF
19
Show member pathways
11.82 CXCL8 IL6 TLR4
20 11.79 CXCL8 IL6 TLR4 TNF
21 11.78 CXCL8 IL6 TLR4
22
Show member pathways
11.72 CXCL8 PTGS2 TNF
23 11.69 CXCL8 IL6 TLR4 TNF
24 11.66 CXCL8 EGF HBEGF UPK3A
25 11.64 CXCL8 HBEGF IL6
26 11.56 CXCL8 EGF IL6 TNF
27
Show member pathways
11.53 CXCL8 IL6 PTGS2 TNF
28 11.51 CXCL8 IL6 PTGS2 TACR1 TLR4 TNF
29 11.5 CXCL8 IL6 PTGS2
30 11.49 HBEGF IL6 TNF
31 11.46 IL6 KNG1 TNF
32 11.45 CXCL8 IL6 TLR4 TNF
33 11.36 CXCL8 IL6 PTGS2 TNF
34 11.31 CXCL8 IL6 TLR4 TNF
35 11.3 IL6 TLR4 TNF
36 10.48 TAC1 TACR1
37 10.3 CRP CXCL8 IL6 PTGS2 TNF

GO Terms for Cystitis

Cellular components related to Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.97 CKAP4 EGF FZD8 HBEGF KNG1 P2RX3
2 extracellular region GO:0005576 9.65 CRP CXCL8 EGF HBEGF IL6 KNG1
3 extracellular space GO:0005615 9.28 CRP CXCL8 EGF HBEGF IL6 KNG1

Biological processes related to Cystitis according to GeneCards Suite gene sharing:

(show all 38)
# Name GO ID Score Top Affiliating Genes
1 angiogenesis GO:0001525 9.95 CXCL8 EGF FZD8 PTGS2
2 positive regulation of gene expression GO:0010628 9.93 CRP EGF IL6 NGF TLR4 TNF
3 response to lipopolysaccharide GO:0032496 9.91 CXCL8 PTGS2 TAC1 TLR4
4 positive regulation of apoptotic process GO:0043065 9.91 IL6 KNG1 NGF PTGS2 TNF TRPV1
5 positive regulation of cytosolic calcium ion concentration GO:0007204 9.87 KNG1 TAC1 TACR1 TRPV1
6 cellular response to lipopolysaccharide GO:0071222 9.85 CXCL8 IL6 TLR4 TNF
7 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.84 EGF HBEGF IL6
8 regulation of inflammatory response GO:0050727 9.84 PTGS2 TLR4 TNF
9 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.83 IL6 PTGS2 TNF
10 regulation of blood pressure GO:0008217 9.82 PTGS2 TAC1 TACR1
11 response to glucocorticoid GO:0051384 9.81 IL6 PTGS2 TNF
12 positive regulation of interleukin-6 production GO:0032755 9.77 IL6 TLR4 TNF
13 response to heat GO:0009408 9.75 P2RX3 TACR1 TRPV1
14 positive regulation of smooth muscle cell proliferation GO:0048661 9.71 HBEGF IL6 PTGS2 TNF
15 negative regulation of ERBB signaling pathway GO:1901185 9.68 EGF HBEGF
16 cellular response to ATP GO:0071318 9.67 PTGS2 TRPV1
17 positive regulation of synaptic transmission, GABAergic GO:0032230 9.67 TAC1 TACR1
18 response to pain GO:0048265 9.67 TAC1 TACR1 TRPV1
19 sensory perception of pain GO:0019233 9.67 PTGS2 TAC1 TACR1 TRPV1
20 positive regulation of acute inflammatory response GO:0002675 9.66 IL6 TAC1
21 negative regulation of blood vessel diameter GO:0097756 9.65 CRP PTGS2
22 positive regulation of chemokine production GO:0032722 9.65 IL6 TLR4 TNF
23 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.62 TLR4 TNF
24 tachykinin receptor signaling pathway GO:0007217 9.62 TAC1 TACR1
25 positive regulation of action potential GO:0045760 9.61 TAC1 TACR1
26 positive regulation of fever generation GO:0031622 9.59 PTGS2 TNF
27 urinary bladder smooth muscle contraction GO:0014832 9.58 P2RX3 TRPV1
28 detection of abiotic stimulus GO:0009582 9.56 TAC1 TACR1
29 positive regulation of saliva secretion GO:0046878 9.54 TAC1 TACR1
30 smooth muscle contraction involved in micturition GO:0060083 9.52 TACR1 TRPV1
31 positive regulation of synaptic transmission, cholinergic GO:0032224 9.51 TAC1 TACR1
32 behavioral response to pain GO:0048266 9.5 P2RX3 TACR1 TRPV1
33 negative regulation of lipid storage GO:0010888 9.43 CRP IL6 TNF
34 positive regulation of lymphocyte proliferation GO:0050671 9.33 TAC1 TACR1 TLR4
35 inflammatory response GO:0006954 9.32 CRP CXCL8 IL6 KNG1 PTGS2 TAC1
36 positive regulation of nitric oxide biosynthetic process GO:0045429 9.26 PTGS2 TLR4 TNF TRPV1
37 regulation of signaling receptor activity GO:0010469 10.04 CXCL8 HBEGF IL6 NGF TNF
38 negative regulation of cell proliferation GO:0008285 10.03 CXCL8 IL6 NGF PTGS2 UMOD

Molecular functions related to Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.35 FZD8 KNG1 NGF TAC1 TLR4
2 growth factor activity GO:0008083 8.92 EGF HBEGF IL6 NGF

Sources for Cystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
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49 NCI
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51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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