MCID: CYS003
MIFTS: 28

Cystitis Cystica

Categories: Nephrological diseases

Aliases & Classifications for Cystitis Cystica

MalaCards integrated aliases for Cystitis Cystica:

Name: Cystitis Cystica 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:7138
ICD9CM 34 595.81
NCIt 50 C96230
SNOMED-CT 67 13285005
UMLS 71 C0152262

Summaries for Cystitis Cystica

Disease Ontology : 12 A cysititis that is characterized by hyperplasia of bladder submucosa and cyst formation caused by chronic irritation of the bladder.

MalaCards based summary : Cystitis Cystica is related to urethral syndrome and glandular cystitis. An important gene associated with Cystitis Cystica is KRT7 (Keratin 7), and among its related pathways/superpathways are Cytoskeletal Signaling and Glycosaminoglycan degradation. Affiliated tissues include prostate, spinal cord and cervix.

Wikipedia : 74 Cystitis cystica is a rare chronic reactive inflammatory disorder thought to be caused by chronic... more...

Related Diseases for Cystitis Cystica

Diseases related to Cystitis Cystica via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 182)
# Related Disease Score Top Affiliating Genes
1 urethral syndrome 31.8 KRT20 KLK3
2 glandular cystitis 30.8 KRT7 KRT20 CDX2
3 appendix adenocarcinoma 30.0 KRT7 KRT20 CDX2
4 mucinous adenocarcinoma 30.0 KRT7 KRT20 CDX2
5 chronic cystitis 29.7 UPK2 KRT7 KRT20 CDX2
6 bladder adenocarcinoma 29.6 KRT7 KRT20 KLK3 CDX2
7 bladder cancer 28.4 UPK2 SPAM1 KRT20 HYAL1
8 cystitis 10.9
9 urinary tract infection 10.4
10 acute cystitis 10.3
11 pyelitis 10.3
12 ovary neuroendocrine neoplasm 10.3 KRT7 CDX2
13 anal canal paget's disease 10.3 KRT7 CDX2
14 anal paget's disease 10.3 KRT7 CDX2
15 anal gland adenocarcinoma 10.3 KRT7 CDX2
16 ureter adenocarcinoma 10.3 KRT7 CDX2
17 anus adenocarcinoma 10.3 KRT7 CDX2
18 mucinous adenofibroma 10.3 KRT7 CDX2
19 pancreatic foamy gland adenocarcinoma 10.3 KRT7 CDX2
20 adenosquamous colon carcinoma 10.2 KRT7 CDX2
21 bile duct adenoma 10.2 KRT7 KRT20
22 bartholin's gland disease 10.2 KRT7 CDX2
23 bartholin's gland carcinoma 10.2 KRT7 CDX2
24 mucinous intrahepatic cholangiocarcinoma 10.2 KRT7 CDX2
25 ovarian seromucinous carcinoma 10.2 KRT7 CDX2
26 rectum neuroendocrine neoplasm 10.2 KRT7 CDX2
27 urethral villous adenoma 10.2 KRT7 KRT20
28 appendiceal neoplasm 10.2 KRT7 CDX2
29 bladder benign neoplasm 10.2 KRT7 KRT20
30 nephrogenic adenoma of urinary bladder 10.2 KRT7 KRT20
31 atrophic vulva 10.2 KRT7 KRT20
32 small cell carcinoma of the bladder 10.2 KRT7 KRT20
33 pancreatic serous cystadenocarcinoma 10.2 KRT7 KRT20
34 rectosigmoid junction neoplasm 10.2 KRT7 KRT20
35 transverse colon cancer 10.2 KRT7 KRT20
36 mucinous stomach adenocarcinoma 10.2 KRT7 CDX2
37 urinary bladder small cell neuroendocrine carcinoma 10.2 KRT7 KRT20
38 vulvar apocrine adenocarcinoma 10.2 KRT7 KRT20
39 eyelid carcinoma 10.2 KRT7 KRT20
40 esophageal adenosquamous carcinoma 10.2 KRT7 CDX2
41 jejunal neoplasm 10.2 KRT7 KRT20
42 colonic lymphangioma 10.2 KRT7 KRT20
43 thymus adenocarcinoma 10.2 KRT20 CDX2
44 intratubular embryonal carcinoma 10.2 KRT7 KRT20
45 malignant syringoma 10.2 KRT7 KRT20
46 ovarian large-cell neuroendocrine carcinoma 10.2 KRT7 KRT20
47 papillary transitional carcinoma 10.2 KRT7 KRT20
48 nasal cavity olfactory neuroblastoma 10.2 KRT7 CDX2
49 supine hypotensive syndrome 10.2 KRT7 KRT20
50 meibomian cyst 10.2 KRT7 KRT20

Comorbidity relations with Cystitis Cystica via Phenotypic Disease Network (PDN):


Acute Cystitis Bladder Cancer
Bladder Neck Obstruction Hydronephrosis
Prostate Cancer Prostatic Hypertrophy
Urethral Stricture

Graphical network of the top 20 diseases related to Cystitis Cystica:



Diseases related to Cystitis Cystica

Symptoms & Phenotypes for Cystitis Cystica

Drugs & Therapeutics for Cystitis Cystica

Search Clinical Trials , NIH Clinical Center for Cystitis Cystica

Genetic Tests for Cystitis Cystica

Anatomical Context for Cystitis Cystica

MalaCards organs/tissues related to Cystitis Cystica:

40
Prostate, Spinal Cord, Cervix

Publications for Cystitis Cystica

Articles related to Cystitis Cystica:

(show top 50) (show all 161)
# Title Authors PMID Year
1
Vesicular Cystitis: A Chronic Cystitis Variant Often Unresponsive to Antibiotics and Electrofulguration. 61
33070139 2021
2
Difficult cystoscopy due to "Elongated" urethra- think of pelvic lipomatosis. 61
33251114 2021
3
Well-differentiated neuroendocrine tumors of the lower urinary tract: biologic behavior of a rare entity. 61
33301750 2020
4
Bladder Exstrophy Polyp: An Uncommon Entity in Surgical Pathology. 61
33252291 2020
5
Bladder outlet obstruction secondary to posterior urethral cystitis cystica & glandularis in a 12-year-old boy. A rare case scenario. 61
33102121 2020
6
Incidence of adenocarcinoma bladder in patients with cystitis cystica et glandularis: A retrospective study. 61
33376267 2020
7
Cystitis Cystica on Routine Cystoscopy at Time of Total Laparoscopic Hysterectomy. 61
30735732 2019
8
Is trigonitis a neglected, imprecise, misunderstood, or forgotten diagnosis? 61
30989795 2019
9
Mimickers of urothelial neoplasia. 61
30380401 2019
10
Diagnostic Value of Glucose Transporter 1 (GLUT-1) Expression in Nested Variant of Urothelial Carcinoma. 61
30035295 2019
11
Cystitis cystica and glandularis producing large bladder masses in a 16-year-old boy. 61
29552345 2018
12
Cystitis Cystica Glandularis: Radiological Imitator of Urothelial Carcinoma. 61
29421770 2018
13
Intravesicular administration of sodium hyaluronate ameliorates the inflammation and cell proliferation of cystitis cystica et glandularis involving interleukin-6/JAK2/Stat3 signaling pathway. 61
29162939 2017
14
Cystitis glandularis: Management and challenges in a renal transplant recipient. 61
28717279 2017
15
Correlation of Bladder Histopathologic Changes Due to Double-J Stenting to the Period of Stenting: A Preliminary Study. 61
28467731 2017
16
Cystitis Cystica as a Large Solitary Bladder Cyst. 61
28466074 2017
17
Prolapsing cystitis cystica causing bladder outlet obstruction: An unusual complication. 61
27843222 2016
18
Differential diagnosis of bladder versus colorectal adenocarcinoma: keratin 7 and GATA3 positivity in nuclear ß-catenin-negative glandular tumours defines adenocarcinoma of the bladder. 61
26463756 2016
19
Carcinoma of the Uterine Cervix Involving the Genitourinary Tract: A Potential Diagnostic Dilemma. 61
26426382 2016
20
Urinary Bladder Adenocarcinoma Metastatic to the Abdominal Wall: Report of a Case with Cytohistologic Correlation. 61
27006847 2016
21
Suburothelial and extrinsic lesions of the urinary bladder: radiologic and pathologic features with emphasis on MR imaging. 61
26048699 2015
22
[Ferdinand Albert Wilhelm von Brunn (1849-1895): Rostock's contribution to urology at the end of the 19th century]. 61
25875930 2015
23
Distinguishing nested variants of urothelial carcinoma from benign mimickers by TERT promoter mutation. 61
25118812 2015
24
Extensive xanthogranulomatous cystitis mimicking bladder cancer. 61
25371622 2014
25
Ultrasound distinction between simple recurrent urinary tract infections and a specific bladder wall inflammatory entity called cystitis cystica. 61
24851610 2014
26
Long-term incidence of febrile UTI after DxHA treatment of VUR. 61
23810062 2014
27
Ultrasound bladder wall thickness measurement in diagnosis of recurrent urinary tract infections and cystitis cystica in prepubertal girls. 61
23725853 2013
28
Positive feedback loop for cystitis cystica: the effect of recurrent urinary tract infection on the number of bladder wall mucosa nodules. 61
24696993 2013
29
Inverted papilloma of the bladder: a review and an analysis of the recent literature of 365 patients. 61
22520573 2013
30
Metaplastic conditions of the bladder. 61
24127673 2013
31
[Primary large cell neuroendocrine carcinoma of the urinary bladder]. 61
23641713 2013
32
Primary adenocarcinoma of the urinary bladder: differential diagnosis and clinical relevance. 61
23451748 2013
33
Microcystic variant of urothelial carcinoma. 61
24363668 2013
34
Urinary bladder sinuses: a novel morphologic lesion with clinical and pathologic significance. 61
22495363 2012
35
Nonneoplastic lesions of the prostate and bladder. 61
22742546 2012
36
Genitourinary schistosomiasis: life cycle and radiologic-pathologic findings. 61
22786992 2012
37
Recurrent transitional cell carcinoma of the bladder: A mixed nested variant case report and literature review. 61
22511434 2012
38
A rare case of recurrent urinary obstruction and acute renal failure from cystitis cystica et glandularis. 61
22511438 2012
39
Cystitis cystica and cystitis glandularis causing ureteral obstruction. 61
22266000 2012
40
Malignant glandular lesions and glandular differentiation in invasive/noninvasive urothelial carcinoma of the urinary bladder. 61
21855380 2011
41
Polyps and masses of the pediatric urinary bladder: a 21-year pathology review. 61
21793666 2011
42
Glandular lesions of the urinary bladder:clinical significance and differential diagnosis. 61
20854477 2011
43
Primary carcinoid tumors of the urinary bladder and prostatic urethra: a clinicopathologic study of 6 cases. 61
21317716 2011
44
Cystitis cystica and recurrent urinary tract infections in children. 61
20977079 2010
45
Nested variant of urothelial carcinoma: a clinicopathologic and immunohistochemical study of 30 pure and mixed cases. 61
19800100 2010
46
Rare etiology of obstructive uropathy: pelvic lipomatosis. 61
20215833 2010
47
Urothelial carcinoma with villoglandular differentiation: a study of 14 cases. 61
19593329 2009
48
Urachal carcinoma: a clinicopathologic analysis of 24 cases with outcome correlation. 61
19252435 2009
49
Morphological evaluation of cystitis glandularis. 61
19332913 2009
50
Cystitis glandularis forming a tumorous lesion in the urinary bladder: A rare appearance of disease. 61
19468518 2008

Variations for Cystitis Cystica

Expression for Cystitis Cystica

Search GEO for disease gene expression data for Cystitis Cystica.

Pathways for Cystitis Cystica

Pathways related to Cystitis Cystica according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.62 KRT7 KRT20 FSCN1
2
Show member pathways
9.92 SPAM1 HYAL1

GO Terms for Cystitis Cystica

Cellular components related to Cystitis Cystica according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.02 UPK2 KRT7 KLK3 HYAL1 FSCN1

Biological processes related to Cystitis Cystica according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hyaluronan catabolic process GO:0030214 8.62 SPAM1 HYAL1

Molecular functions related to Cystitis Cystica according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hyalurononglucosaminidase activity GO:0004415 8.62 SPAM1 HYAL1

Sources for Cystitis Cystica

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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