MCID: CYS003
MIFTS: 34

Cystitis Cystica

Categories: Nephrological diseases

Aliases & Classifications for Cystitis Cystica

MalaCards integrated aliases for Cystitis Cystica:

Name: Cystitis Cystica 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:7138
ICD9CM 36 595.81
NCIt 51 C96230
SNOMED-CT 69 13285005
UMLS 74 C0152262

Summaries for Cystitis Cystica

MalaCards based summary : Cystitis Cystica is related to glandular cystitis and urethral syndrome. An important gene associated with Cystitis Cystica is HYAL1 (Hyaluronidase 1), and among its related pathways/superpathways are Pathways in cancer and Cytoskeletal Signaling. Affiliated tissues include kidney, prostate and breast, and related phenotypes are digestive/alimentary and immune system

Wikipedia : 77 A urinary tract infection (UTI) is an infection that affects part of the urinary tract. When it affects... more...

Related Diseases for Cystitis Cystica

Diseases related to Cystitis Cystica via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 179)
# Related Disease Score Top Affiliating Genes
1 glandular cystitis 31.3 CDX2 KRT20 KRT7
2 urethral syndrome 11.4
3 cystitis 10.9
4 bladder carcinoma in situ 10.5 KRT7 UPK2
5 duodenum adenocarcinoma 10.5 CDX2 KRT7
6 cribriform carcinoma 10.5 GATA3 KRT7
7 vulval paget's disease 10.5 KRT20 KRT7
8 bile duct adenoma 10.5 KRT20 KRT7
9 vulvar sarcoma 10.5 AR KRT7
10 apocrine sweat gland neoplasm 10.5 KRT5 KRT7
11 morpheaform basal cell carcinoma 10.5 AR KRT20
12 apocrine adenocarcinoma 10.5 AR KRT5
13 bladder papillary transitional cell neoplasm 10.4 KRT20 TERT
14 urinary tract papillary transitional cell benign neoplasm 10.4 KRT20 TERT
15 cystic basal cell carcinoma 10.4 KRT20 KRT7
16 vaginal benign neoplasm 10.4 CDX2 KRT20
17 vaginal adenoma 10.4 CDX2 KRT20
18 vaginal tubulovillous adenoma 10.4 CDX2 KRT20
19 transverse colon cancer 10.4 KRT20 KRT7
20 mucopolysaccharidosis, type ix 10.4 HYAL1 SPAM1
21 balloon cell malignant melanoma 10.4 KRT5 KRT7
22 benign breast adenomyoepithelioma 10.4 KRT5 KRT7
23 malignant syringoma 10.4 KRT20 KRT7
24 prostate transitional cell carcinoma 10.4 CTNNB1 KLK3
25 bartholin's duct cyst 10.4 AR GATA3
26 appendix adenocarcinoma 10.4 CDX2 KRT20 KRT7
27 gastric signet ring cell adenocarcinoma 10.4 CDX2 GATA3 UPK2
28 jejunal adenocarcinoma 10.4 CDX2 KRT20 KRT7
29 ovarian mucinous adenocarcinoma 10.4 CDX2 KRT20 KRT7
30 mucinous adenocarcinoma 10.4 CDX2 KRT20 KRT7
31 thymus adenocarcinoma 10.4 CDX2 KRT20 KRT7
32 seminal vesicle adenocarcinoma 10.4 KLK3 KRT20 KRT7
33 appendix disease 10.4 CDX2 KRT20 KRT7
34 malignant spiradenoma 10.4 KRT5 KRT7
35 chronic cystitis 10.4 CDX2 KRT20 KRT7
36 papillary transitional carcinoma 10.4 KRT20 KRT7
37 vulva adenocarcinoma 10.4 CDX2 KRT20 KRT7
38 rectum adenocarcinoma 10.4 CDX2 KRT20 KRT7
39 eyelid carcinoma 10.4 KRT20 KRT7
40 signet ring cell adenocarcinoma 10.4 CDX2 KRT20 KRT7
41 inverted transitional papilloma 10.4 GATA3 KRT5 KRT7
42 large intestine adenocarcinoma 10.4 CTNNB1 KRT20 KRT7
43 lung acinar adenocarcinoma 10.4 CTNNB1 KRT20 KRT7
44 mucinous bronchioloalveolar adenocarcinoma 10.4 CDX2 KRT20 KRT7
45 krukenberg carcinoma 10.4 KRT20 KRT7
46 ampulla of vater adenocarcinoma 10.4 CDX2 KRT20 KRT7
47 benign mesothelioma 10.4 KRT5 KRT7
48 endocervical adenocarcinoma 10.4 CDX2 KRT20 KRT7
49 cervical adenocarcinoma 10.4 CDX2 KRT20 KRT7
50 atrophy of prostate 10.4 KLK3 SLC2A1

Comorbidity relations with Cystitis Cystica via Phenotypic Disease Network (PDN):


Acute Cystitis Bladder Cancer
Bladder Neck Obstruction Hydronephrosis
Prostate Cancer Prostatic Hypertrophy
Urethral Stricture

Graphical network of the top 20 diseases related to Cystitis Cystica:



Diseases related to Cystitis Cystica

Symptoms & Phenotypes for Cystitis Cystica

MGI Mouse Phenotypes related to Cystitis Cystica:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.97 AR CDX2 CTNNB1 GAST GATA3 KRT5
2 immune system MP:0005387 9.9 AR CDH17 CTNNB1 FSCN1 GAST GATA3
3 embryo MP:0005380 9.86 AR CDX2 CTNNB1 FSCN1 GATA3 MCL1
4 mortality/aging MP:0010768 9.73 AR CDX2 CTNNB1 FSCN1 GAST GATA3
5 normal MP:0002873 9.23 AR CDX2 CTNNB1 GATA3 MCL1 SYP

Drugs & Therapeutics for Cystitis Cystica

Search Clinical Trials , NIH Clinical Center for Cystitis Cystica

Genetic Tests for Cystitis Cystica

Anatomical Context for Cystitis Cystica

MalaCards organs/tissues related to Cystitis Cystica:

42
Kidney, Prostate, Breast, Lung, Thymus, Appendix, Testis

Publications for Cystitis Cystica

Articles related to Cystitis Cystica:

(show top 50) (show all 52)
# Title Authors Year
1
Cystitis Cystica on Routine Cystoscopy at Time of Total Laparoscopic Hysterectomy. ( 30735732 )
2019
2
Cystitis Cystica Glandularis: Radiological Imitator of Urothelial Carcinoma. ( 29421770 )
2018
3
Cystitis cystica and glandularis producing large bladder masses in a 16-year-old boy. ( 29552345 )
2018
4
Intravesicular administration of sodium hyaluronate ameliorates the inflammation and cell proliferation of cystitis cystica et glandularis involving interleukin-6/JAK2/Stat3 signaling pathway. ( 29162939 )
2017
5
Cystitis Cystica as a Large Solitary Bladder Cyst. ( 28466074 )
2017
6
Prolapsing cystitis cystica causing bladder outlet obstruction: An unusual complication. ( 27843222 )
2016
7
Ultrasound distinction between simple recurrent urinary tract infections and a specific bladder wall inflammatory entity called cystitis cystica. ( 24851610 )
2014
8
Positive feedback loop for cystitis cystica: the effect of recurrent urinary tract infection on the number of bladder wall mucosa nodules. ( 24696993 )
2013
9
Ultrasound bladder wall thickness measurement in diagnosis of recurrent urinary tract infections and cystitis cystica in prepubertal girls. ( 23725853 )
2013
10
Cystitis cystica and cystitis glandularis causing ureteral obstruction. ( 22266000 )
2012
11
A rare case of recurrent urinary obstruction and acute renal failure from cystitis cystica et glandularis. ( 22511438 )
2012
12
Cystitis cystica and recurrent urinary tract infections in children. ( 20977079 )
2010
13
Role of cystitis cystica et glandularis and intestinal metaplasia in development of bladder carcinoma. ( 18455631 )
2008
14
Giant botryoid fibroepithelial polyp of bladder with myofibroblastic stroma and cystitis cystica et glandularis. ( 12574920 )
2003
15
Cystitis cystica glandularis masquerading as a bladder tumor. ( 12452616 )
2001
16
Pseudotumoral cystitis cystica of the urethra in a boy. ( 9126107 )
1997
17
Cytology of cystitis cystica glandularis of the bladder--a case report. ( 9009484 )
1996
18
Ultrastructural observations on cystitis cystica in human bladder urothelium. ( 8435733 )
1993
19
Cystitis cystica treated with the neodymium-YAG laser. Case report. ( 1871562 )
1991
20
Pelvic lipomatosis with cystitis cystica, cystitis glandularis and adenocarcinoma of the bladder: first reported case. ( 2183756 )
1990
21
Single polypoid cystitis cystica and glandularis presenting as benign bladder tumor. ( 2219622 )
1990
22
Vaginal leiomyoma as a cause of pelvic pain and cystitis cystica. ( 2808027 )
1989
23
Prostate specific antigen and acid phosphatase-reactive cells in cystitis cystica and glandularis. ( 2454618 )
1988
24
Metaplastic cystitis complicated with Von Brunn nests, cystitis cystica, and intestinal type of glandular metaplasia. ( 3400142 )
1988
25
Cystitis cystica: an electron and immunofluorescence microscopic study. ( 3560344 )
1987
26
Cystitis cystica simulating bladder tumor at sonography. ( 3920259 )
1985
27
Cystitis cystica and cystitis glandularis: cause of bladder mass. ( 6833575 )
1983
28
Cystitis cystica in childhood: clinical findings and treatment procedures. ( 7136633 )
1982
29
Cystitis cystica and glandularis: an unusual complication of terminal ileitis. A case report with discussion of its significance. ( 7234994 )
1981
30
Antibody-dependent cytotoxicity to transitional cells in cystitis cystica. ( 7241687 )
1981
31
Cystitis cystica, cystitis glandularis, and Brunn's nests in a feline urinary bladder. ( 7467060 )
1981
32
The prevalence and significance of Brunn's nests, cystitis cystica and squamous metaplasia in normal bladders. ( 470001 )
1979
33
The clinical significant of cystitis cystica in girls: results of a prospective study. ( 660739 )
1978
34
Cystitis cystica (cystosis) with bladder cancer. ( 671624 )
1978
35
Cystitis cystica: characteristics of the disease in children. ( 837048 )
1977
36
Cystitis cystica: Proliferative epithelial lesion in urinary bladder. ( 1246792 )
1976
37
Cystitis cystica masquerading as a bladder tumor. ( 4592207 )
1974
38
Secretory immunoglobulin-A excretion in cystitis cystica. ( 4588626 )
1973
39
The incidence of cell nests, cystitis cystica and cystitis glandularis in the lower urinary tract revealed by autopsies. ( 5052250 )
1972
40
Cystitis cystica in childhood. ( 5443851 )
1970
41
Cystitis cystica and glandularis: a study of 40 cases. ( 5445558 )
1970
42
Simultaneous occurrence of medullary sponge kidney and pyelo-uretero-cystitis cystica. ( 5379088 )
1969
43
Neoplasia of the bladder and cystitis cystica. ( 6022024 )
1967
44
CONTRASTING CASES OF CYSTITIS CYSTICA. ( 14282081 )
1965
45
Is cystitis cystica an innocent or a malefic lesion? ( 13296152 )
1956
46
Is cystitis cystica an innocent or a malefic lesion? ( 13281875 )
1955
47
An uncommon bladder condition simulating carcinoma; glandular proliferation in the epithelium of the urinary tract, with special reference to cystitis cystica and cystitis glandularis. ( 18107321 )
1948
48
Cystitis cystica as a single tumor. ( 18903554 )
1948
49
Pyelitis, ureteritis and cystitis cystica. ( 20990735 )
1946
50
A case of pyelitis and cystitis cystica. ( 21013272 )
1946

Variations for Cystitis Cystica

Expression for Cystitis Cystica

Search GEO for disease gene expression data for Cystitis Cystica.

Pathways for Cystitis Cystica

GO Terms for Cystitis Cystica

Cellular components related to Cystitis Cystica according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.28 CTNNB1 FSCN1 HYAL1 KLK3 KRT5 KRT7
2 cell projection membrane GO:0031253 8.96 CTNNB1 FSCN1

Biological processes related to Cystitis Cystica according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 9.61 KRT20 KRT5 KRT7
2 positive regulation of cell differentiation GO:0045597 9.5 AR CDX2 GATA3
3 cellular process GO:0009987 9.4 AR CTNNB1
4 regulation of systemic arterial blood pressure GO:0003073 9.37 AR KLK3
5 epithelial cell differentiation involved in prostate gland development GO:0060742 9.26 AR CTNNB1
6 positive regulation of epithelial cell proliferation involved in prostate gland development GO:0060769 9.16 AR CTNNB1
7 regulation of nephron tubule epithelial cell differentiation GO:0072182 8.96 CTNNB1 GATA3
8 cell fate determination GO:0001709 8.8 CTNNB1 GATA3 MCL1

Molecular functions related to Cystitis Cystica according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hyalurononglucosaminidase activity GO:0004415 8.62 HYAL1 SPAM1

Sources for Cystitis Cystica

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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