MCID: CYT002
MIFTS: 34

Cytokine Deficiency

Categories: Rare diseases
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Aliases & Classifications for Cytokine Deficiency

MalaCards integrated aliases for Cytokine Deficiency:

Name: Cytokine Deficiency 19
Cytokine 16 75

Classifications:



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Summaries for Cytokine Deficiency

MalaCards based summary: Cytokine Deficiency, also known as cytokine, is related to car t cell therapy-associated cytokine release syndrome and asthma. The drugs Zinc cation and Infliximab have been mentioned in the context of this disorder. Affiliated tissues include t cells, bone marrow and nk cells.

Wikipedia: 75 Cytokines are a broad and loose category of small proteins (~5-25 kDa) important in cell signaling.... more...

Related Diseases for Cytokine Deficiency

Diseases related to Cytokine Deficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 2528)
# Related Disease Score Top Affiliating Genes
1 car t cell therapy-associated cytokine release syndrome 11.3
2 asthma 11.1
3 immunodeficiency 33 11.0
4 immunodeficiency 92 11.0
5 hemophagocytic lymphohistiocytosis, familial, 1 11.0
6 kshv inflammatory cytokine syndrome 11.0
7 hemophagocytic lymphohistiocytosis 11.0
8 cytokine receptor deficiency 11.0
9 myelofibrosis 11.0
10 mycosis fungoides 10.9
11 granulomatosis with polyangiitis 10.9
12 multicentric castleman disease 10.9
13 immunodeficiency 68 10.9
14 crisponi/cold-induced sweating syndrome 1 10.9
15 autoimmune disease 10.9
16 lymphoproliferative syndrome, x-linked, 2 10.9
17 immunodeficiency 67 10.9
18 immunodeficiency 23 10.9
19 autoimmune disease, multisystem, infantile-onset, 1 10.9
20 immunodeficiency 72 with autoinflammation 10.9
21 janus kinase-3 deficiency 10.9
22 hemophagocytic reticulosis 10.9
23 fatal post-viral neurodegenerative disorder 10.9
24 inflammatory bowel disease-recurrent sinopulmonary infections syndrome 10.9
25 viral infectious disease 10.8
26 adult respiratory distress syndrome 10.8
27 rheumatoid arthritis 10.8
28 covid-19 10.8
29 arthritis 10.7
30 proteasome-associated autoinflammatory syndrome 1 10.7
31 toxic shock syndrome 10.7
32 dermatitis, atopic 10.7
33 severe acute respiratory syndrome 10.7
34 dermatitis 10.7
35 leukemia 10.7
36 periodontitis 10.7
37 inflammatory bowel disease 10.7
38 hepatitis 10.7
39 leptin deficiency or dysfunction 10.7
40 severe covid-19 10.7
41 mycobacterium tuberculosis 1 10.7
42 systemic lupus erythematosus 10.6
43 immune deficiency disease 10.6
44 allergic disease 10.6
45 leishmaniasis 10.6
46 hypereosinophilic syndrome 10.6
47 type 1 diabetes mellitus 10.6
48 lupus erythematosus 10.6
49 multiple sclerosis 10.6
50 severe combined immunodeficiency 10.6

Graphical network of the top 20 diseases related to Cytokine Deficiency:



Diseases related to Cytokine Deficiency

Symptoms & Phenotypes for Cytokine Deficiency

Drugs & Therapeutics for Cytokine Deficiency

Drugs for Cytokine Deficiency (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 349)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Zinc cation Approved, Experimental, Investigational Phase 4 7440-66-6, 23713-49-7 32051
2
Infliximab Approved Phase 4 170277-31-3
3
Fluorouracil Approved Phase 4 51-21-8 3385
4
Oxaliplatin Approved, Investigational Phase 4 61825-94-3 43805 11947679 6857599
5
Fluoxetine Approved, Vet_approved Phase 4 54910-89-3 3386
6
Dexmedetomidine Approved, Experimental, Vet_approved Phase 4 86347-14-0, 113775-47-6 68602 5311068
7
Hydrocortisone succinate Approved Phase 4 2203-97-6 3643
8
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
9
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 3640 5754
10
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
11
Azithromycin Approved Phase 4 83905-01-5 447043
12
Etanercept Approved, Investigational Phase 4 185243-69-0
13
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
14
Ibuprofen Approved Phase 4 15687-27-1 3672
15
Diclofenac Approved, Vet_approved Phase 4 15307-86-5, 15307-79-6 3033
16
Tocopherol Approved, Investigational Phase 4 1406-66-2
17
Acetylcysteine Approved, Investigational Phase 4 616-91-1 581 12035
18
Omalizumab Approved, Investigational Phase 4 242138-07-4
19
Histamine Approved, Investigational Phase 4 51-45-6 774
20
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
21
Nitroglycerin Approved, Investigational Phase 4 55-63-0 4510
22
Copper Approved, Investigational Phase 4 7440-50-8 27099
23
Nifedipine Approved Phase 4 21829-25-4 4485
24
Iron Approved Phase 4 7439-89-6 29936
25
Amisulpride Approved, Investigational Phase 4 71675-85-9, 53583-79-2 2159
26
Valproic acid Approved, Investigational Phase 4 99-66-1 3121
27
Dopamine Approved Phase 4 62-31-7, 51-61-6 681
28
Clozapine Approved Phase 4 5786-21-0 2818 135398737
29
Imiquimod Approved, Investigational Phase 4 99011-02-6 57469
30
Nitrofurantoin Approved, Vet_approved Phase 4 67-20-9 5353830
31
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
32
Citalopram Approved Phase 4 59729-32-7, 59729-33-8 2771
33
Etoposide Approved Phase 4 33419-42-0 36462
34
Aflibercept Approved Phase 4 862111-32-8 124490314
35
Ranibizumab Approved Phase 4 347396-82-1
36
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3 3680
37
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 3003 5743
38
Temozolomide Approved, Investigational Phase 4 85622-93-1 5394
39
Dimercaprol Approved Phase 4 59-52-9 3080
40
Oseltamivir Approved Phase 4 204255-11-8, 196618-13-0 65028
41
Ceftriaxone Approved Phase 4 73384-59-5 5479530
42
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
43
Ofloxacin Approved Phase 4 82419-36-1 4583
44
Budesonide Approved Phase 4 51333-22-3 5281004 40000 63006
45
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
46
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
47
Cholecalciferol Approved, Nutraceutical, Vet_approved Phase 4 67-97-0, 1406-16-2 5280795 10883523
48
DL-alpha-Tocopherol Approved, Experimental, Investigational, Nutraceutical, Vet_approved Phase 4 59-02-9, 10191-41-0 2116 14985
49
Ascorbic acid Approved, Nutraceutical Phase 4 50-81-7 54676860 54670067 5785
50
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 22737-96-8, 68-26-8 5280382 445354

Interventional clinical trials:

(show top 50) (show all 511)
# Name Status NCT ID Phase Drugs
1 Predictors of Treatment Response to Aflibercept and Aqueous Cytokine Levels in Patients With Persistent Diabetic Macular Edema Following Treatment With Ranibizumab: An Interventional Prospective Study Unknown status NCT02651168 Phase 4
2 Intraocular Cytokine Changes in Recurrence of Polypoidal Choroidal Vasculopathy Unknown status NCT02976194 Phase 4 ranibizumab
3 Pancreatitis CytoSorbents (CytoSorb®) Inflammatory Cytokine Removal: A Prospective Study. Unknown status NCT03082469 Phase 4
4 The Effect of Xolair on Inhibiting Leukotriene and Cytokine (IL-4 and IL-13) Release From Blood Basophils Unknown status NCT00673218 Phase 4 Placebo;Xolair
5 Cytokine Profile and Metal Ion Concentrations at Patients Undergoing a Revision THR Unknown status NCT00289679 Phase 4
6 Intervention Study Measuring Inflammatory Cytokine Levels in the Serum of Patients Who Underwent an Acute MI, and the Influence of Vitamin D on These Levels Unknown status NCT01115842 Phase 4 Vitamin D
7 The Impact of Vitamin A Supplementation on Gene Expression of Cytokine Secreted by CD4+ T Lymphocyte in Multiple Sclerosis Patients Unknown status NCT01407211 Phase 4
8 The Effect of Vitamin A Supplementation on Gene Expression of Cytokine Secreted by T CD4+ Lymphocyte in Atherosclerotic Patients Unknown status NCT01414972 Phase 4 Vitamin A;placebo
9 The Effects of Intravitral Ozurdex Implant in DME: Cytokine Change in Aqueous Humor Unknown status NCT03475407 Phase 4 Ozurdex intravitreal injection
10 Pharmacogenetics in Anti-VEGF Treatment Non-responders Suffering Exudative Age-related Macular Degeneration (AMD): Genetic Correlations and Intraocular Cytokine Concentrations Unknown status NCT01213667 Phase 4 Ranibizumab
11 Clinical Efficacy of Chemotherapy Combined With Cytokine-induced Killer in Treatment of Patients With Colon Cancer Completed NCT03084809 Phase 4 Cytokine-induced killer cells+ FOLFOX4;FOLFOX4
12 Fluoxetine to Reduce Intubation and Death After COVID19 Infection Completed NCT04377308 Phase 4 Fluoxetine
13 The Effect of Dexmedetomidine for Suprascapular Nerve Block With Axillary Nerve Block on Plasma Cortisol and Pain-related Cytokines After Arthroscopic Rotator Cuff Repair: a Randomized Controlled Trial Completed NCT04398589 Phase 4 Dexmedetomidine injection;Saline injection
14 TOCILIZUMAB - An Option for Patients With COVID-19 Associated Cytokine Release Syndrome; A Single Center Experience Completed NCT04730323 Phase 4 Tocilizumab
15 EFFECTS OF NSAIDs ON CLINICAL OUTCOMES, SYNOVIAL FLUID CYTOKINE CONCENTRATION AND SIGNAL TRANSDUCTION PATHWAYS IN KNEE OSTEOARTHRITIS Completed NCT01860833 Phase 4 Ibuprofen;Celecoxib;Diclofenac
16 Influence of N-Acetylcysteine on Morbidity, Oxygenation and Cytokine Levels in Partial or Total Esophagectomy for Cancer. A Multicenter, Prospective, Randomised Double Blind, Placebo-controlled Study Completed NCT00512265 Phase 4 n-acetylcysteine;250mL glucose 5%
17 The Effect of Xolair (Omalizumab) on Inhibiting Leukotriene and Cytokine (IL-4 and IL-13) Release From Blood Basophils Completed NCT00657891 Phase 4 Omalizumab;Placebo
18 The Effect of Preoperative Topical Ketorolac 0.45% on Aqueous Cytokine Levels and Macular Thickness in Diabetic and Non Diabetic Patients Undergoing Cataract Surgery Completed NCT02646072 Phase 4 Ketorolac tromethamine ophthalmic solution 0.45%
19 Effect of Antioxidants on Ocular Blood Flow, Endothelial Function, and Cytokine Levels in LPS Induced Inflammatory Model in Humans. Completed NCT00431691 Phase 4 vitamin and mineral supplement;Escherichia coli Endotoxin (LPS);100% O2;nitroglycerin
20 TNF-α Blockade for Psoriatic Arthritis - A Clinical and MRI Study, and the Effects on Cytokine and Cardiovascular Risk Profile Completed NCT00432406 Phase 4 Infliximab;Etanercept
21 The Effect of Zinc, Beta-carotene, and Vitamin D3 Supplementation as Pro-inflammation Mediated Regulator in Preterm Delivery Through Placental Protein Adaptor MyD88 and TRIF, Transcription Factor NFkB, and Pro-inflammatory Cytokine IL-1β Completed NCT03005496 Phase 4 Zinc;Nifedipine;Beta Carotene;Vitamin D3;Dexamethasone
22 Disturbance of Plasma Cytokine Parameters in Clozapine-Resistant Treatment-Refractory Schizophrenia (CTRS) and Their Association With Combination Therapy Completed NCT03652974 Phase 4 sodium valproate with Clozapine;amisulpride with Clozapine;placebo with Clozapine
23 A Multi-Center, Open-Label Study Evaluating the Cytokine and Eyelid Margin Bacterial Load Levels of Subjects Diagnosed With Chronic Blepharitis Following Dosing With AzaSite® (Azithromycin Ophthalmic Solution) 1% Completed NCT00629941 Phase 4 AzaSite®
24 Preoperative Versus Postoperative Ultrasound-guided Rectus Sheath Block for Improving Pain, Sleep Quality and Cytokine Levels of Patients With Open Midline Incisions Undergoing Transabdominal Gynaecological Operation Completed NCT02477098 Phase 4 preoperative 0.5% ropivacaine hydrochloride preoperative;postoperative 0.5% Ropivacaine hydrochloride
25 Phenotype and Cytokine Production Characteristics of T Cells From Alopecia Areata Scalp Skin Before and After Aldara 5% Cream Using Flow Cytometry Completed NCT00176943 Phase 4 Aldara Cream 5%
26 Recurrent Urinary Tract Infections in Children: Bacterial Identification, Antibiotic Susceptibility Profiling and Cytokine Levels Associated With Antibiotic Prophylaxis Completed NCT02357758 Phase 4 Antibiotic Prophylaxis
27 Effect of Preemptive Epidural Analgesia in Labor on Pro and Anti-inflammatory Cytokine Production in a Mother and a Newborn Completed NCT00361712 Phase 4 Standard of care
28 The Role of Cytokine-Serotonin Interactions in Post-Stroke Depression Completed NCT00254020 Phase 4 Citalopram
29 Effects of Fingolimod (Gilenya®) on Cytokine and Chemokine Levels in Relapsing Remitting Multiple Sclerosis Patients Completed NCT02373098 Phase 4 Fingolimod 0.5 mg
30 Predictors of Treatment Response to Aflibercept and Aqueous Cytokine Levels in Treatment Naïve Patients With Diabetic Macular Edema Completed NCT02441907 Phase 4 aflibercept
31 Anti Cytokine Combination Therapy With Daclizumab and Infliximab for Treatment of Steroid Refractory Acute GVHD Completed NCT00574470 Phase 4 daclizumab, infliximab
32 Effect of Steroids Given Over 24 Hours on Cytokine Release and Urinary Desmosine Levels in Patients Undergoing Bilateral Total Knee Replacement Completed NCT01399268 Phase 4 Hydrocortisone;Saline
33 Robust Antibody and Cytokine Response to Hepatitis B Vaccine Among Not-in-treatment Patients With Chronic Hepatitis C:An Open-label Control Study in China Completed NCT02898922 Phase 4
34 Clinical Study on the Treatment of Pediatric Hemophagocytic Lymphohistiocytosis Based on Cytokine Guided Risk Stratification:A Multicenter Randomized Controlled Study Recruiting NCT05491304 Phase 4 Dexamethasone;Etoposide;Ruxolitinib
35 Cytokine and Visual Outcome Variations in Eyes Receiving a Variable Dosing Ranibizumab Treatment: The COVERT Study Recruiting NCT03056092 Phase 4 Intravitreal ranibizumab
36 Cytokine and Visual Outcome Variations in Eyes Receiving a Variable Dosing Aflibercept Treatment: The COVARIANT Study Recruiting NCT03056079 Phase 4 Intravitreal aflibercept
37 The Pharmacokinetics of Aqueous Dexamethasone and the Inflammatory Cytokine Response After Treatment With a Dexamethasone Intracanalicular Insert - The CYTODEX Study Active, not recruiting NCT04667507 Phase 4 Dexamethasone Ophthalmic implant
38 A Study of CIK in Combination With Temozolomide With and Without Radiation in Adults With Advanced Malignant Gliomas Not yet recruiting NCT02496988 Phase 4 Temozolomide
39 A Randomized, Open Label Study to Evaluate the Effect of Tamiflu on Viral Shedding and on Serum and Cytoplasmic Inflammatory Cytokine Concentrations in Patients With Laboratory-confirmed Influenza Terminated NCT00436124 Phase 4 oseltamivir [Tamiflu]
40 Comparison Between Ceftriaxone and Levofloxacin on Cytokine Expression Over Time in Severe Pneumococcal Pneumonia Terminated NCT00429975 Phase 4 levofloxacin;ceftriaxone
41 Cytokine Change in Bronchoalveolar Lavage Fluid After Early Budesonide-Surfactant Treatment in Premature Infants Terminated NCT00146497 Phase 4 Budesonide-Surfactant
42 Propofol Versus Midazolam for Sedation in Mechanically Ventilated Critically Ill Patients Who Presented With Traumatic Brain Injury: Cytokine Response and Neuropsychological Assessment (IRRC#1201M) Terminated NCT01712477 Phase 4 Intravenous sedation using propofol;Intravenous sedation with midazolam
43 Comparison of the Treatment Efficacy of High-Dose Corticosteroid and Tocilizumab During Clinical Worsening in Patients With COVID-19 Pneumonia Withdrawn NCT05133635 Phase 4 Methylprednisolone;Tocilizumab
44 Impact of Statins on Cytokine Expression in Pneumonia Withdrawn NCT00946166 Phase 4 simvastatin;Placebo
45 To Determine the Efficacy of Neurokinin 1 Receptor Antagonist as a Therapeutic Tool Against Cytokine Storm and Respiratory Failure in Covid-19 Patients Unknown status NCT04468646 Phase 3 NK-1R antagonist
46 Anti-inflammatory/Antioxidant Oral Nutrition Supplementation on the Cytokine Storm and Progression of COVID-19: A Randomized Controlled Trial Unknown status NCT04323228 Phase 2, Phase 3
47 The Effectiveness and Safety of Adjuvant Cytokine-induced Killer Cell Immunotherapy for Stage III Colorectal Cancer Patients After Chemotherapy Unknown status NCT02280278 Phase 3 Adjuvant chemotherapy
48 Single Center, Prospective, Randomized, Partly-Double Blinded, Controlled Trial to Assess the Safety and Feasibility of Intracoronary Cell Infusion Mobilized With G-CSF and Darbepoetin and Their Effects on Improvement of Cardiac Function in Patients With Myocardial Infarction: Myocardial Regeneration and Angiogenesis in Myocardial Infarction With G-CSF and Erythropoietin Mobilization and Intra-Coronary Cell Infusion -5-Combination Cytokine Therapy Trial Unknown status NCT00501917 Phase 2, Phase 3 G-CSF with/without darbepoetin, peripheral blood stem cell infusion
49 Evaluation of Cytokine-induced Killer (CIK) Cells as Therapy or Adjuvant Treatment for Patients With Advanced Hepatocelluler Carcinoma Unknown status NCT02568748 Phase 3
50 Maintenance Immunotherapy With Autologous Cytokine-induced Killer Cells for Stage IIIb/IV Nonsquamous Non-small Cell Lung Cancer Unknown status NCT01481259 Phase 2, Phase 3

Search NIH Clinical Center for Cytokine Deficiency

Genetic Tests for Cytokine Deficiency

Anatomical Context for Cytokine Deficiency

Organs/tissues related to Cytokine Deficiency:

MalaCards : T Cells, Bone Marrow, Nk Cells, Lung, Endothelial, Liver, Smooth Muscle

Publications for Cytokine Deficiency

Articles related to Cytokine Deficiency:

(show top 50) (show all 30021)
# Title Authors PMID Year
1
Cytokine nanosponges suppressing overactive macrophages and dampening systematic cytokine storm for the treatment of hemophagocytic lymphohistiocytosis. 62
36185750 2023
2
Time to face the proofs: the BCG Moreau vaccine promotes superior inflammatory cytokine profile in vitro when compared with Russia, Pasteur, and Danish strains. 62
34766868 2022
3
Tanshinone IIA alleviates ovalbumin-induced allergic rhinitis symptoms by inhibiting Th2 cytokine production and mast cell histamine release in mice. 62
35167426 2022
4
A Systematic Review of Inflammatory Cytokine Changes Following Aneurysmal Subarachnoid Hemorrhage in Animal Models and Humans. 62
35260989 2022
5
Comprehensive analysis of cytokine adsorption properties of polymethyl methacrylate (PMMA) membrane material. 62
35301606 2022
6
Natural products and their derivatives as immune check point inhibitors: Targeting cytokine/chemokine signalling in cancer. 62
35772610 2022
7
Extracellular DNA levels and cytokine profiles in preterm birth: a cohort study. 62
35218368 2022
8
Preincubation of donor tissue with a VEGF cytokine trap promotes subsequent high-risk corneal transplant survival. 62
34810177 2022
9
Evaluation of periodontal status and cytokine levels in saliva and gingival crevicular fluid of patients with inflammatory bowel diseases. 62
35665507 2022
10
Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection. 62
35505004 2022
11
Multiple Cytokine Analysis of Th1/Th2/Th9/Th17/Th22/Treg Cytokine Pathway for Individual Immune Profile Assessment in Patients with Psoriasis. 62
36419330 2022
12
A novel oncolytic virus induces a regional cytokine storm and safely eliminates malignant ascites of colon cancer. 62
35510373 2022
13
The impact of HCV eradication on hyperglycemia, insulin resistance, cytokine production, and insulin receptor substrate-1 and 2 expression in patients with HCV infection. 62
34757525 2022
14
Cell division cycle 42 positively correlates with T helper 2 cytokine, effusion viscosity, and hearing loss degree in otitis media with effusion patients. 62
36164754 2022
15
Can the hyperthermia-mediated heat shock factor/heat shock protein 70 pathway dampen the cytokine storm during SARS-CoV-2 infection? 62
33314076 2022
16
Distinct Immune Phenotypes and Cytokine Profiles in Children with Differing Severity of COVID-19. 62
36102684 2022
17
Interleukin-6 Antagonists: Lessons From Cytokine Release Syndrome to the Therapeutic Application in Severe COVID-19 Infection. 62
33759631 2022
18
Association of Pregnancy With Coronavirus Cytokine Storm: Systematic Review and Meta-analysis. 62
35319475 2022
19
From Cytokine Storm to Cytokine Breeze: Did Lessons Learned from Immunopathogenesis Improve Immunomodulatory Treatment of Moderate-to-Severe COVID-19? 62
36289881 2022
20
Relationship between cytokine storm and SARS-CoV-2 infection's worsening. 62
35135040 2022
21
Exploring the angiographic-biologic phenotype in the IMAGINE study: quantitative UWFA and cytokine expression. 62
34099465 2022
22
SARS-CoV-2 Variants Show a Gradual Declining Pathogenicity and Pro-Inflammatory Cytokine Stimulation, an Increasing Antigenic and Anti-Inflammatory Cytokine Induction, and Rising Structural Protein Instability: A Minimal Number Genome-Based Approach. 62
36215001 2022
23
Severity of Cytokine Release Syndrome Influences Outcome After Axicabtagene Ciloleucel for Large B cell Lymphoma: Results from the US Lymphoma CAR-T Consortium. 62
35780055 2022
24
Interleukin-6 cytokine: An overview of the immune regulation, immune dysregulation, and therapeutic approach. 62
35969896 2022
25
Acupuncture and its effect on cytokine and chemokine profiles in seasonal allergic rhinitis: a preliminary three-armed, randomized, controlled trial. 62
35301577 2022
26
Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker-high and -low severe asthma. 62
35579040 2022
27
Zinc Oxide Tetrapods Modulate Wound Healing and Cytokine Release In Vitro-A New Antiproliferative Substance in Glaucoma Filtering Surgery. 62
36362846 2022
28
Punicalagin and ellagic acid containing Punica granatum L. fruit rind extract prevents vincristine-induced neuropathic pain in rats: an in silico and in vivo evidence of GABAergic action and cytokine inhibition. 62
34369317 2022
29
Increased cytokine gene expression and cognition risk associated with androgen deprivation therapy. 62
35821621 2022
30
Upregulation of hsa_circ_0004812 promotes COVID-19 cytokine storm via hsa-miR-1287-5p/IL6R, RIG-I axis. 62
35989496 2022
31
Cytokine alterations in pediatric internalizing disorders: Systematic review and exploratory multi-variate meta-analysis. 62
35880170 2022
32
Envelope-based partial partial least squares with application to cytokine-based biomarker analysis for COVID-19. 62
36111618 2022
33
Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model. 62
34666219 2022
34
Ascorbic acid attenuates activation and cytokine production in sepsis-like monocytes. 62
35141934 2022
35
Human cardiac organoids to model COVID-19 cytokine storm induced cardiac injuries. 62
35689600 2022
36
Peritoneal M2 macrophage-derived extracellular vesicles as natural multitarget nanotherapeutics to attenuate cytokine storms after severe infections. 62
35792186 2022
37
IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses. 62
36075894 2022
38
Cytokine release syndrome-like serum responses after COVID-19 vaccination are frequent and clinically inapparent under cancer immunotherapy. 62
35715501 2022
39
Human lung-resident mucosal-associated invariant T cells are abundant, express antimicrobial proteins, and are cytokine responsive. 62
36085311 2022
40
Cytokine Mixtures Mimicking the Local Milieu in Patients with Inflammatory Bowel Disease Impact Phenotype and Function of Mesenchymal Stromal Cells. 62
35984079 2022
41
Comprehensive Serum Proteome Profiling of Cytokine Release Syndrome and Immune Effector Cell-Associated Neurotoxicity Syndrome Patients with B-Cell ALL Receiving CAR T19. 62
35705524 2022
42
Comparative evaluation of host immune response and cytokine signature pertaining to Th1 and Th2 immune arms in serum and tissue among patients of acute localised vs. chronic disseminated dermatophytosis. 62
35673954 2022
43
Cytokine storm and neuropathological alterations in patients with neurological manifestations of COVID-19. 62
36089786 2022
44
Cytokine profile in tear and aqueous humor of primary open-angle patients as a prognostic factor for trabeculectomy outcome. 62
34812085 2022
45
Maternal Mid-Gestation Cytokine Dysregulation in Mothers of Children with Autism Spectrum Disorder. 62
34505185 2022
46
Cytokine Receptor Diversity in the Lamprey Predicts the Minimal Essential Cytokine Networks of Vertebrates. 62
35914837 2022
47
Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19. 62
36083891 2022
48
A Mendelian randomization cytokine screen reveals IL-13 as causal factor in risk of severe COVID-19. 62
35618154 2022
49
Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll-like receptors dictates pathophysiology of COVID-19 disease. 62
35538614 2022
50
Liposome encapsulated clodronate mediated elimination of pathogenic macrophages and microglia: A promising pharmacological regime to defuse cytokine storm in COVID-19. 62
35721801 2022

Variations for Cytokine Deficiency

Expression for Cytokine Deficiency

Search GEO for disease gene expression data for Cytokine Deficiency.

Pathways for Cytokine Deficiency

GO Terms for Cytokine Deficiency

Sources for Cytokine Deficiency

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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