MCID: CYT005
MIFTS: 53

Cytomegalovirus Retinitis

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Cytomegalovirus Retinitis

MalaCards integrated aliases for Cytomegalovirus Retinitis:

Name: Cytomegalovirus Retinitis 12 54 45 15 17 74
Cmv Retinitis 12 56

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

Disease Ontology 12 DOID:0080160
MeSH 45 D017726
UMLS 74 C0206178

Summaries for Cytomegalovirus Retinitis

Disease Ontology : 12 A retinitis that has material basis in Cytomegalovirus.

MalaCards based summary : Cytomegalovirus Retinitis, also known as cmv retinitis, is related to uveitis and pars planitis. An important gene associated with Cytomegalovirus Retinitis is IL10RA (Interleukin 10 Receptor Subunit Alpha), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Cidofovir and Ganciclovir have been mentioned in the context of this disorder. Affiliated tissues include eye, t cells and retina, and related phenotypes are cellular and hematopoietic system

Wikipedia : 77 Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that... more...

Related Diseases for Cytomegalovirus Retinitis

Diseases related to Cytomegalovirus Retinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 275)
# Related Disease Score Top Affiliating Genes
1 uveitis 30.2 HLA-B IFNG IL10 TNF
2 pars planitis 29.9 HLA-A HLA-B
3 choroiditis 29.8 IL10 TNF
4 anterior uveitis 29.7 HLA-A HLA-B
5 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 29.6 CCR5 CD9 IFNG IL10
6 arthritis 29.6 CSF2 IFNG IL10 TNF
7 cytomegalovirus infection 29.5 HLA-A HLA-B TNF
8 leprosy 3 29.5 IFNG IL10 TNF
9 acquired immunodeficiency syndrome 29.4 CCR2 CCR5 CSF2 HLA-B IFNG IL10
10 colitis 29.4 IFNG IL10 IL10RA TNF
11 tuberculoid leprosy 29.4 IFNG IL10
12 common variable immunodeficiency 29.3 IFNG IL10 TNF
13 rheumatic disease 29.2 HLA-B IFNG IL10 TNF
14 human immunodeficiency virus infectious disease 29.1 CCR2 CCR5 IFNG IL10 TNF
15 hematopoietic stem cell transplantation 29.0 HLA-A HLA-B IFNG IL10 TNF
16 toxoplasmosis 29.0 CCR5 IFNG IL10 TNF
17 rheumatoid arthritis 28.8 CCR2 CSF2 HLA-B IFNG IL10 TNF
18 aplastic anemia 28.6 CSF2 HLA-A HLA-B IFNG TNF
19 diabetes mellitus 28.3 CCR5 HLA-A HLA-B IFNG TNF
20 human immunodeficiency virus type 1 27.9 CCR2 CCR5 CD9 HLA-A HLA-B IFNG
21 retinitis 11.2
22 retinal detachment 10.5
23 granulocytopenia 10.3 CSF2 TNF
24 indeterminate leprosy 10.3 HLA-B TNF
25 giant cell myocarditis 10.3 HLA-B IL10RA
26 leukemia 10.3
27 cyclic neutropenia 10.3 CSF2 IFNG
28 cryptococcal meningitis 10.3 CSF2 IFNG
29 carotid artery thrombosis 10.3 CSF2 IFNG
30 human t-cell leukemia virus type 2 10.3 CSF2 IFNG
31 lymphoma 10.3
32 acute disseminated encephalomyelitis 10.3 HLA-B IL10
33 drug reaction with eosinophilia and systemic symptoms 10.3 HLA-B TNF
34 erythema multiforme 10.3 IFNG TNF
35 bacterial sepsis 10.3 IL10 TNF
36 microscopic colitis 10.2 IFNG TNF
37 autoimmune gastritis 10.2 IL10 TNF
38 crohn's colitis 10.2 IFNG TNF
39 autoimmune disease of eyes, ear, nose and throat 10.2 IL10 TNF
40 pleural tuberculosis 10.2 IFNG TNF
41 posterior uveitis 10.2 IFNG TNF
42 scrub typhus 10.2 IL10 TNF
43 lacrimal apparatus disease 10.2 IL10 TNF
44 central nervous system vasculitis 10.2 IFNG TNF
45 multidrug-resistant tuberculosis 10.2 IL10 TNF
46 lichen disease 10.2 IFNG TNF
47 tuberculous peritonitis 10.2 IFNG TNF
48 soft tissue sarcoma 10.2 IFNG TNF
49 transverse myelitis 10.2 IL10 TNF
50 inflammatory bowel disease 25, autosomal recessive 10.2 IL10 IL10RA

Graphical network of the top 20 diseases related to Cytomegalovirus Retinitis:



Diseases related to Cytomegalovirus Retinitis

Symptoms & Phenotypes for Cytomegalovirus Retinitis

MGI Mouse Phenotypes related to Cytomegalovirus Retinitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.08 CCR2 CCR5 CD9 CSF2 IFNG IL10
2 hematopoietic system MP:0005397 10.03 CCR2 CCR5 CD9 CSF2 IFNG IL10
3 immune system MP:0005387 10.01 CCR2 CCR5 CD9 CSF2 IFNG IL10
4 digestive/alimentary MP:0005381 9.93 CCR2 CCR5 IFNG IL10 IL10RA TNF
5 neoplasm MP:0002006 9.8 CCR2 CCR5 CSF2 IFNG IL10 TNF
6 liver/biliary system MP:0005370 9.77 CCR2 CCR5 IFNG IL10 TNF
7 reproductive system MP:0005389 9.63 CCR5 CD9 CSF2 IFNG IL10 TNF
8 no phenotypic analysis MP:0003012 9.56 CCR2 IFNG IL10 TNF
9 respiratory system MP:0005388 9.43 CCR2 CD9 CSF2 IFNG IL10 TNF
10 skeleton MP:0005390 9.1 CCR2 CD9 CSF2 IFNG IL10 TNF

Drugs & Therapeutics for Cytomegalovirus Retinitis

Drugs for Cytomegalovirus Retinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 108)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cidofovir Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 113852-37-2 60613
2
Ganciclovir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 82410-32-0 3454
3
Foscarnet Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 4428-95-9, 63585-09-1 3415
4
Probenecid Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 57-66-9 4911
5
Phosphonoacetic Acid Experimental Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 4408-78-0 546
6 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
7 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
8 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
9 Ganciclovir triphosphate Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
10 Anti-Retroviral Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
11 Reverse Transcriptase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
12 Antirheumatic Agents Phase 4,Phase 2,Phase 1,Not Applicable
13 Renal Agents Phase 4,Phase 2,Phase 1,Not Applicable
14
Valganciclovir Approved, Investigational Phase 3,Not Applicable 175865-60-8 64147
15
Sargramostim Approved, Investigational Phase 3,Not Applicable 123774-72-1, 83869-56-1
16
Acyclovir Approved Phase 3,Not Applicable 59277-89-3 2022
17 Immunologic Factors Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
18 Antineoplastic Agents, Immunological Phase 2, Phase 3
19 Antibodies Phase 2, Phase 3,Phase 1,Not Applicable
20 Antibodies, Monoclonal Phase 2, Phase 3,Phase 1
21 Immunoglobulins Phase 2, Phase 3,Phase 1,Not Applicable
22
Nelfinavir Approved Phase 2 159989-64-7 64143
23
protease inhibitors Phase 2
24 HIV Protease Inhibitors Phase 2
25 Anti-HIV Agents Phase 2,Phase 1,Not Applicable
26
Aldesleukin Approved Phase 1 110942-02-4, 85898-30-2
27 Analgesics, Non-Narcotic Phase 1
28 Peripheral Nervous System Agents Phase 1
29 Interleukin-2 Phase 1
30 Analgesics Phase 1
31
Zidovudine Approved Not Applicable 30516-87-1 35370
32
Interferon beta-1b Approved Not Applicable 145155-23-3
33
Haloperidol Approved 52-86-8 3559
34
Zolpidem Approved 82626-48-0 5732
35
Rocuronium Approved 119302-91-9, 143558-00-3 441290
36
Alfentanil Approved, Illicit 71195-58-9 51263
37
Ciprofloxacin Approved, Investigational 85721-33-1 2764
38
Piperacillin Approved 66258-76-2 43672
39
Warfarin Approved 81-81-2 54678486 6691
40
Aminocaproic Acid Approved, Investigational 60-32-2 564
41
Sevelamer Approved 52757-95-6
42
Oxycodone Approved, Illicit, Investigational 76-42-6 5284603
43
Cefepime Approved, Investigational 88040-23-7 5479537
44
Bosentan Approved, Investigational 147536-97-8 104865
45
Molindone Approved 7416-34-4 23897
46
Nafcillin Approved, Investigational 985-16-0, 147-52-4 8982
47
Labetalol Approved 36894-69-6 3869
48
Spironolactone Approved 1952-01-7, 52-01-7 5833
49
Nifedipine Approved 21829-25-4 4485
50
Methylprednisolone hemisuccinate Approved 2921-57-5

Interventional clinical trials:

(show top 50) (show all 68)
# Name Status NCT ID Phase Drugs
1 Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis Completed NCT00000894 Phase 4 Cidofovir;Probenecid;Ganciclovir
2 A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium) Completed NCT00002125 Phase 4 Foscarnet sodium
3 Pharmacokinetics of Cidofovir During Continuous Venovenous Hemofiltration Completed NCT01866397 Phase 4
4 Use of Cidofovir for Recurrent Respiratory Papillomatosis Completed NCT00205374 Phase 4 Cidofovir;Placebo
5 Valganciclovir in Patients With CMV Retinitis and AIDS Who Cannot Take Drugs by Injection Unknown status NCT00017784 Phase 3 Valganciclovir
6 A Randomized, Controlled Study of Intravenous Ganciclovir Therapy for Peripheral Cytomegalovirus Retinitis in Patients With AIDS Completed NCT00000688 Phase 3 Ganciclovir
7 Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT) Completed NCT00000134 Phase 3 Ganciclovir;Foscarnet
8 Studies of the Ocular Complications of AIDS (SOCA)--Monoclonal Antibody CMV Retinitis Trial (MACRT) Completed NCT00000135 Phase 2, Phase 3 MSL-109
9 A Treatment Protocol for the Use of Intravenous Ganciclovir in AIDS Patients With Immediately Sight-Threatening CMV Retinitis Completed NCT00000698 Phase 3 Ganciclovir
10 Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT) Completed NCT00000143 Phase 3 Cidofovir intravenous
11 Studies of the Ocular Complications of AIDS (SOCA)--Foscarnet-Ganciclovir CMV Retinitis Trial (FGCRT) Completed NCT00000136 Phase 3 Foscarnet;Ganciclovir
12 Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis Completed NCT00002070 Phase 3 Sargramostim;Ganciclovir
13 Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT) Completed NCT00000142 Phase 2, Phase 3 Cidofovir
14 Ganciclovir Implant Study for Cytomegalovirus Retinitis Completed NCT00000118 Phase 3
15 A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes Completed NCT00002377 Phase 3 Valganciclovir;Ganciclovir
16 Valganciclovir in Prevention of Cytomegalovirus (CMV) Reactivation Following Allogeneic-Stem Cell Transplantation (SCT) Completed NCT00330018 Phase 3 Valganciclovir;Acyclovir
17 A Randomized Comparison of Intravitreal ISIS 2922 Plus Ganciclovir Versus Ganciclovir as Treatment for Patients With Cytomegalovirus Retinitis ( CMVR ) Completed NCT00002156 Phase 2 Fomivirsen sodium;Ganciclovir
18 Phase II Randomized Study of Cidofovir for Peripheral Cytomegalovirus Retinitis Completed NCT00004794 Phase 2 cidofovir
19 A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure Completed NCT00000691 Phase 2 Foscarnet sodium
20 CMV Retinitis Retreatment Trial Completed NCT00000766 Phase 2 Foscarnet sodium;Ganciclovir
21 The Safety and Effectiveness of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Completed NCT00002437 Phase 2 Cidofovir;Probenecid
22 The Safety and Effectiveness of ISIS 2922 in Patients With AIDS Who Have Cytomegalovirus (CMV) of the Eyes Completed NCT00002356 Phase 2 Fomivirsen sodium
23 A Study of Viracept in AIDS Patients With Cytomegalovirus Retinitis Completed NCT00002169 Phase 2 Nelfinavir mesylate
24 A Phase II/III Trial of Human Anti-CMV Monoclonal Antibody MSL 109 (MACRT) Completed NCT00000836 Phase 2 Sevirumab
25 Comparison of Two Methods in the Treatment of Cytomegalovirus of the Eyes in Patients With AIDS Completed NCT00001061 Phase 2 Sevirumab;Foscarnet sodium;Ganciclovir
26 The Safety and Effectiveness of Ganciclovir in the Prevention of Cytomegalovirus (CMV) of the Eyes and Disease of the Stomach and Intestines in Patients With HIV Completed NCT00001034 Phase 2 Ganciclovir
27 A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Cannot Use Ganciclovir Withdrawn NCT00000697 Phase 2 Foscarnet sodium
28 A Phase I/II Open-Labelled Trial of Intravitreal Ganciclovir Salvage Therapy for AIDS Patients With Active CMV Retinitis Who Are Intolerant of Systemic Therapy Completed NCT00000673 Phase 1 Ganciclovir
29 A Phase I/II Trial to Assess the Safety and Tolerance of Escalating Doses of a Human Anti-Cytomegalovirus Monoclonal Antibody (SDZ MSL-109) in Patients With the Acquired Immunodeficiency Syndrome and CMV Retinitis Completed NCT00002016 Phase 1 Sevirumab
30 Foscarnet Treatment of Serious CMV Retinitis Infection in Patients With Acquired Immunodeficiency Syndrome Completed NCT00000726 Phase 1 Foscarnet sodium
31 A Study of Ganciclovir in the Treatment of Cytomegalovirus of the Eyes Completed NCT00001062 Phase 1 Ganciclovir
32 A Study of Foscarnet Plus Ganciclovir in the Treatment of Cytomegalovirus of the Eye in Patients With AIDS Who Have Already Been Treated With Ganciclovir Completed NCT00000970 Phase 1 Foscarnet sodium;Ganciclovir
33 A Phase I Study of the Safety of Proleukin (Aldesleukin) in Combination With Ganciclovir and Antiretroviral Therapy in HIV Seropositive Patients With Cytomegalovirus (CMV) Retinitis Completed NCT00002321 Phase 1 Aldesleukin
34 A Phase I Pharmacokinetic and Tolerance Study of 28-Day Regimens of Oral Ganciclovir Completed NCT00000668 Phase 1 Ganciclovir
35 A Pharmacokinetic and Tolerance Study of Oral Ganciclovir in HIV-Infected Children With Asymptomatic Cytomegalovirus Infection and Low CD4 Cell Counts or Quiescent Cytomegalovirus Disease Completed NCT00000805 Phase 1 Ganciclovir
36 A Study of Cidofovir in HIV-Infected Children With Cytomegalovirus (CMV) Disease Withdrawn NCT00000881 Phase 1 Cidofovir;Probenecid
37 A Study of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Unknown status NCT00002384 Not Applicable Cidofovir
38 A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Have Not Had Success With Ganciclovir Unknown status NCT00002301 Not Applicable Foscarnet sodium
39 Suppression of Cytomegalovirus Retinitis Utilizing High Dose Intravenous Acyclovir and Oral Zidovudine in Patients With AIDS Completed NCT00000693 Not Applicable Zidovudine;Acyclovir
40 A Randomized Controlled Study of the Efficacy and Safety of Maintenance Treatment With Oral Ganciclovir for Newly Diagnosed Cytomegalovirus Retinitis in People With AIDS Completed NCT00002257 Not Applicable Ganciclovir
41 A Randomized, Controlled Study of the Safety and Preventive Efficacy of Oral Ganciclovir When Used in Conjunction With An Intravitreal Ganciclovir Implant in the Treatment of Cytomegalovirus Retinitis Completed NCT00002134 Not Applicable Ganciclovir
42 A Study of the Safety and Tolerance of Long-Term Therapy With Intravenous Cytovene (Ganciclovir Sodium) for Cytomegalovirus Retinitis in Persons With AIDS Completed NCT00002034 Not Applicable Zidovudine;Ganciclovir
43 A Randomized Study Comparing the Safety and Efficacy of Two Regimens of Oral Ganciclovir to Intravenous Ganciclovir Maintenance Therapy for Cytomegalovirus Retinitis in People With AIDS Who Have Received Prior Ganciclovir Therapy Completed NCT00002247 Not Applicable Ganciclovir
44 A Study of ISIS 2922 in the Treatment of Advanced Cytomegalovirus Retinitis Completed NCT00002187 Not Applicable Fomivirsen sodium
45 An Open-Label Study of the Safety and Efficacy of Cidofovir for the Treatment of Relapsing Cytomegalovirus Retinitis in Patients With AIDS Completed NCT00002142 Not Applicable Cidofovir;Probenecid
46 Efficacy of Elevated CD4 Counts on CMV Retinitis Completed NCT00091884
47 Studies of the Ocular Complications of AIDS (SOCA) CMV Retinitis Trial: Foscarnet-Ganciclovir Component Completed NCT00000665 Not Applicable Foscarnet sodium;Ganciclovir
48 A Study of Valganciclovir in the Treatment of Cytomegalovirus (CMV) Retinitis in Patients With AIDS Completed NCT00002222 Not Applicable Valganciclovir
49 HPMPC (Cidofovir) Peripheral CMV Retinitis Trial Protocol Completed NCT00000799 Not Applicable Cidofovir;Probenecid
50 An Open-Label Safety Study of Oral Ganciclovir Maintenance Treatment of CMV Retinitis in People With Limited Venous Access Completed NCT00002135 Not Applicable Ganciclovir

Search NIH Clinical Center for Cytomegalovirus Retinitis

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: cytomegalovirus retinitis

Genetic Tests for Cytomegalovirus Retinitis

Anatomical Context for Cytomegalovirus Retinitis

MalaCards organs/tissues related to Cytomegalovirus Retinitis:

42
Eye, T Cells, Retina, Bone, Lung, Bone Marrow, Testes

Publications for Cytomegalovirus Retinitis

Articles related to Cytomegalovirus Retinitis:

(show top 50) (show all 1083)
# Title Authors Year
1
Cytomegalovirus Retinitis in Children and Adolescents with Acute Leukemia following allogeneic Hematopoietic Stem Cell Transplantation. ( 30972869 )
2019
2
CD4+ cells as a potential biomarker for cytomegalovirus retinitis in children with acute lymphocytic leukemia. ( 30681505 )
2019
3
Cytomegalovirus retinitis, in a diabetic immunocompetent patient, after intravitreal ranibizumab injection. ( 29747535 )
2019
4
Macular oedema due to immune reconstitution uveitis occurring in an HIV-negative patient without cytomegalovirus retinitis. ( 30009623 )
2019
5
Aqueous cytomegalovirus DNA and interleukin-8 determination in management of cytomegalovirus retinitis. ( 30187638 )
2019
6
Active cytomegalovirus retinitis after the start of antiretroviral therapy. ( 30196272 )
2019
7
Use of Letermovir as Salvage Therapy for Drug-Resistant Cytomegalovirus Retinitis. ( 30642941 )
2019
8
A cross-sectional study of cytomegalovirus retinitis in HIV-1 infected adults in Nigeria. ( 30837414 )
2019
9
Concurrent cerebral toxoplasmosis and cytomegalovirus retinitis in a patient with human immunodeficiency virus. ( 30851795 )
2019
10
Cytomegalovirus Retinitis Associated with Lenalidomide Use for Multiple Myeloma in an Immunocompetent Patient. ( 30937202 )
2019
11
Polymerase chain reaction analysis of aqueous humor specimens in the diagnosis of cytomegalovirus retinitis in AIDS patients. ( 30968705 )
2019
12
SOCS and Herpesviruses, With Emphasis on Cytomegalovirus Retinitis. ( 31031749 )
2019
13
A Lymphoma Patient with Cytomegalovirus Retinitis and Post-Autologous Hematopoietic Cell Transplantation Immune Reconstitution Uveitis: A Case Report and Review of the Literature. ( 31033155 )
2019
14
Relationship Between Opacity of Cytomegalovirus Retinitis Lesion Borders and Severity of Immunodeficiency Among People With AIDS. ( 31042791 )
2019
15
Abnormal levels of aqueous humor trace elements in patients with cytomegalovirus retinitis. ( 31065104 )
2019
16
Cytomegalovirus Retinitis during Maintenance Therapy in child with Acute Lymphoblastic Leukemia. ( 31086168 )
2019
17
Cytomegalovirus Retinitis as the First Manifestation of Good Syndrome. ( 27715373 )
2018
18
Cytokine Profiles in Aqueous Humor and Plasma of HIV-infected Individuals with Ocular Syphilis or Cytomegalovirus Retinitis. ( 28081374 )
2018
19
OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN CYTOMEGALOVIRUS RETINITIS: A Longitudinal Study. ( 28145973 )
2018
20
Incidence Rates and Risk Factors for Vision Loss among AIDS-Related Cytomegalovirus Retinitis Patients in Southern Thailand. ( 28323489 )
2018
21
SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN MACULA-INVOLVING CYTOMEGALOVIRUS RETINITIS. ( 28376042 )
2018
22
CYTOMEGALOVIRUS RETINITIS ASSOCIATED WITH OCCLUSIVE VASCULOPATHY IN AN ELDERLY, HUMAN IMMUNODEFICIENCY VIRUS-NEGATIVE MAN. ( 28937523 )
2018
23
Cytomegalovirus retinitis in HIV-negative patients - associated conditions, clinical presentation, diagnostic methods and treatment strategy. ( 29068151 )
2018
24
Synthesis, physicochemical properties and ocular pharmacokinetics of thermosensitive in situ hydrogels for ganciclovir in cytomegalovirus retinitis treatment. ( 29228826 )
2018
25
Spectral domain optical coherence tomography and fundus autofluorescence findings in cytomegalovirus retinitis in HIV-infected patients. ( 29445945 )
2018
26
RAPIDLY PROGRESSIVE NEOVASCULAR GLAUCOMA FROM CYTOMEGALOVIRUS RETINITIS IN A NON-HUMAN IMMUNODEFICIENCY VIRUS PATIENT. ( 29533389 )
2018
27
Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus Retinitis. ( 29560000 )
2018
28
Cytomegalovirus retinitis before and after treatment. ( 29776766 )
2018
29
Suppressor of Cytokine Signaling 1 (SOCS1) and SOCS3 Are Stimulated within the Eye during Experimental Murine Cytomegalovirus Retinitis in Mice with Retrovirus-Induced Immunosuppression. ( 29976680 )
2018
30
Visual prognosis, clinical features, and predisposing factors in non-HIV patients with cytomegalovirus retinitis. ( 30030661 )
2018
31
Ganciclovir-Induced Bullae Formation Secondary to Extravasation in a Patient Being Treated for Cytomegalovirus Retinitis. ( 30039977 )
2018
32
Macular cytomegalovirus retinitis following dexamethasone intravitreal implant combined with phacoemulsification. ( 30127173 )
2018
33
Visual acuity outcomes in cytomegalovirus retinitis: early versus late diagnosis. ( 30206157 )
2018
34
HLA-C Alleles and Cytomegalovirus Retinitis in Brazilian Patients with AIDS. ( 30245869 )
2018
35
Ocular Ischemic Syndrome as the Initial Presenting Feature of Cytomegalovirus Retinitis. ( 30311468 )
2018
36
Cytomegalovirus Retinitis in Primary Immune Deficiency Disease. ( 30327738 )
2018
37
Comparison of intravitreal ganciclovir monotherapy and combination with foscarnet as initial therapy for cytomegalovirus retinitis. ( 30364196 )
2018
38
Spectrum of Newly Diagnosed Cytomegalovirus Retinitis in a Developing Country in the HAART Era. ( 30395753 )
2018
39
Initial intravitreal injection of high-dose ganciclovir for cytomegalovirus retinitis in HIV-negative patients. ( 30526535 )
2018
40
Successively bilateral cytomegalovirus retinitis in immunocompromised patient with Good's syndrome. ( 30588440 )
2018
41
Cytomegalovirus retinitis in the post-cART era. ( 30886765 )
2018
42
Cytomegalovirus Retinitis in Patients With Acquired Immunodeficiency Syndrome After Initiating Antiretroviral Therapy. ( 27984023 )
2017
43
Comparative analysis of cytomegalovirus retinitis and microvascular retinopathy in patients with acquired immunodeficiency syndrome. ( 28944199 )
2017
44
Utility of Leflunomide in the Treatment of Drug Resistant Cytomegalovirus Retinitis. ( 26652481 )
2017
45
In Response to: Jeon and Lee's 'Cytomegalovirus Retinitis in a Human Immunodeficiency Virus-negative Cohort: Long-term Management and Complications'. ( 26943724 )
2017
46
Leukaemic infiltration and cytomegalovirus retinitis in a patient with acute T-cell lymphoblastic leukaemia in complete remission. ( 27402450 )
2017
47
Cytomegalovirus Retinitis in Pediatric Stem Cell Transplants: Report of a Recent Cluster and the Development of a Screening Protocol. ( 27746296 )
2017
48
COMPARISON OF VISUAL PROGNOSIS AND CLINICAL FEATURES OF CYTOMEGALOVIRUS RETINITIS IN HIV AND NON-HIV PATIENTS. ( 28118285 )
2017
49
Cytomegalovirus Retinitis: A Review. ( 28355091 )
2017
50
Bilateral cytomegalovirus retinitis in a healthy infant. ( 28367531 )
2017

Variations for Cytomegalovirus Retinitis

Expression for Cytomegalovirus Retinitis

Search GEO for disease gene expression data for Cytomegalovirus Retinitis.

Pathways for Cytomegalovirus Retinitis

Pathways related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

(show all 46)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.82 CCR2 CCR5 CSF2 HLA-A HLA-B IFNG
2
Show member pathways
13.52 CCR2 CCR5 CSF2 IFNG IL10 IL10RA
3
Show member pathways
13.27 CCR2 CCR5 CSF2 IL10 IL10RA TNF
4
Show member pathways
13.15 CCR2 CCR5 CSF2 IL10 IL10RA TNF
5
Show member pathways
12.82 CCR5 CSF2 HLA-A HLA-B IL10RA TNF
6
Show member pathways
12.72 CCR2 CCR5 CSF2 HLA-A HLA-B IFNG
7
Show member pathways
12.69 HLA-A HLA-B IFNG IL10 IL10RA TNF
8
Show member pathways
12.53 IFNG IL10 IL10RA TNF
9
Show member pathways
12.49 IFNG IL10 IL10RA TNF
10 12.47 CCR2 IFNG IL10 TNF
11
Show member pathways
12.39 CCR5 CSF2 IFNG IL10 TNF
12
Show member pathways
12.38 CSF2 HLA-A HLA-B IFNG TNF
13 12.27 CSF2 HLA-A HLA-B TNF
14
Show member pathways
12.2 CSF2 IFNG TNF
15 12.17 CCR5 HLA-A HLA-B
16 12.14 IFNG IL10 IL10RA TNF
17
Show member pathways
12.14 HLA-A HLA-B IFNG IL10 TNF
18
Show member pathways
12.1 CCR2 CCR5 CSF2 IFNG IL10 IL10RA
19
Show member pathways
12.04 CCR5 IFNG IL10 IL10RA TNF
20 12.01 CCR2 CCR5 IL10RA
21
Show member pathways
11.97 IFNG IL10 TNF
22
Show member pathways
11.95 CSF2 IFNG TNF
23 11.93 CCR2 IFNG TNF
24
Show member pathways
11.89 CCR5 HLA-A IFNG
25 11.89 CSF2 IFNG IL10 TNF
26 11.83 CD9 CSF2 TNF
27 11.79 CSF2 IFNG TNF
28 11.78 CSF2 IFNG IL10 TNF
29 11.72 IFNG IL10 TNF
30
Show member pathways
11.69 CSF2 IFNG TNF
31 11.66 CCR2 CCR5 IFNG IL10 IL10RA
32 11.6 CCR2 CSF2 TNF
33 11.6 CSF2 IFNG IL10 TNF
34
Show member pathways
11.59 CSF2 IFNG TNF
35
Show member pathways
11.57 HLA-A IFNG TNF
36 11.56 CSF2 IFNG IL10 TNF
37 11.46 IFNG IL10 TNF
38 11.45 CCR2 IFNG TNF
39 11.31 IFNG IL10 TNF
40 11.28 IL10 IL10RA TNF
41 11.2 IFNG TNF
42 11.11 IFNG IL10
43 11.09 CSF2 IL10 TNF
44 11.08 HLA-A HLA-B
45 10.92 CSF2 IFNG IL10 TNF
46 10.79 CCR2 CCR5 CSF2 IL10 IL10RA TNF

GO Terms for Cytomegalovirus Retinitis

Cellular components related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.56 CCR2 CCR5 CD9 TNF
2 integral component of plasma membrane GO:0005887 9.43 CCR2 CCR5 CD9 HLA-A HLA-B TNF
3 integral component of lumenal side of endoplasmic reticulum membrane GO:0071556 9.32 HLA-A HLA-B
4 MHC class I protein complex GO:0042612 9.16 HLA-A HLA-B
5 cell surface GO:0009986 9.02 CCR5 CD9 HLA-A HLA-B TNF

Biological processes related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

(show all 32)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.9 CSF2 IFNG IL10 TNF
2 inflammatory response GO:0006954 9.86 CCR2 CCR5 IL10 TNF
3 MAPK cascade GO:0000165 9.82 CCR5 CSF2 TNF
4 interferon-gamma-mediated signaling pathway GO:0060333 9.69 HLA-A HLA-B IFNG
5 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.65 CSF2 TNF
6 negative regulation of mitotic cell cycle GO:0045930 9.65 IL10 TNF
7 antigen processing and presentation of peptide antigen via MHC class I GO:0002474 9.64 HLA-A HLA-B
8 negative regulation of interleukin-6 production GO:0032715 9.64 IL10 TNF
9 positive regulation of cytokine secretion GO:0050715 9.63 IL10 TNF
10 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent GO:0002479 9.63 HLA-A HLA-B
11 positive regulation of protein complex assembly GO:0031334 9.62 IFNG TNF
12 positive regulation of T cell mediated cytotoxicity GO:0001916 9.62 HLA-A HLA-B
13 cellular response to lipopolysaccharide GO:0071222 9.62 CCR5 CSF2 IL10 TNF
14 positive regulation of osteoclast differentiation GO:0045672 9.61 IFNG TNF
15 dendritic cell chemotaxis GO:0002407 9.61 CCR2 CCR5
16 humoral immune response GO:0006959 9.61 CCR2 IFNG TNF
17 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.59 IFNG TNF
18 negative regulation of growth of symbiont in host GO:0044130 9.58 IL10 TNF
19 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.58 IL10 TNF
20 positive regulation of podosome assembly GO:0071803 9.57 CSF2 TNF
21 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent GO:0002480 9.55 HLA-A HLA-B
22 endothelial cell apoptotic process GO:0072577 9.54 IL10 TNF
23 antigen processing and presentation of endogenous peptide antigen via MHC class Ib GO:0002476 9.52 HLA-A HLA-B
24 negative regulation of cytokine secretion involved in immune response GO:0002740 9.49 IL10 TNF
25 positive regulation of interleukin-23 production GO:0032747 9.48 CSF2 IFNG
26 protection from natural killer cell mediated cytotoxicity GO:0042270 9.46 HLA-A HLA-B
27 cytokine-mediated signaling pathway GO:0019221 9.43 CCR2 CCR5 CSF2 IL10 IL10RA TNF
28 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.4 IFNG TNF
29 receptor biosynthetic process GO:0032800 9.37 IL10 TNF
30 regulation of synapse organization GO:0050807 9.33 IL10 IL10RA TNF
31 positive regulation of vitamin D biosynthetic process GO:0060557 9.26 IFNG TNF
32 immune response GO:0006955 9.23 CCR2 CCR5 CSF2 HLA-A HLA-B IFNG

Molecular functions related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptide antigen binding GO:0042605 9.4 HLA-A HLA-B
2 chemokine binding GO:0019956 9.32 CCR2 CCR5
3 C-C chemokine binding GO:0019957 9.26 CCR2 CCR5
4 C-C chemokine receptor activity GO:0016493 9.16 CCR2 CCR5
5 chemokine receptor activity GO:0004950 8.96 CCR2 CCR5
6 cytokine activity GO:0005125 8.92 CSF2 IFNG IL10 TNF
7 protein binding GO:0005515 10.07 CCR2 CCR5 CD9 CSF2 HLA-A HLA-B

Sources for Cytomegalovirus Retinitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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