Aliases & Classifications for Dacryoadenitis

MalaCards integrated aliases for Dacryoadenitis:

Name: Dacryoadenitis 12 55 15 73
Dacryocystitis 44 73

Classifications:



External Ids:

Disease Ontology 12 DOID:950
ICD10 33 H04.0 H04.00
ICD9CM 35 375.0 375.00
MeSH 44 D003607
NCIt 50 C26971
SNOMED-CT 68 86927009

Summaries for Dacryoadenitis

MalaCards based summary : Dacryoadenitis, also known as dacryocystitis, is related to mikulicz disease and sialadenitis. An important gene associated with Dacryoadenitis is IL21 (Interleukin 21), and among its related pathways/superpathways are Th1 Differentiation Pathway and B Cell Development Pathways. The drugs Antibodies and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include eye, t cells and thyroid.

Wikipedia : 76 Dacryoadenitis is inflammation of the lacrimal glands (the tear-producing... more...

Related Diseases for Dacryoadenitis

Diseases in the Dacryoadenitis family:

Chronic Dacryoadenitis Acute Dacryoadenitis

Diseases related to Dacryoadenitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 112)
# Related Disease Score Top Affiliating Genes
1 mikulicz disease 33.3 AQP5 IL21
2 sialadenitis 30.6 AQP5 HSPG2
3 sjogren syndrome 29.9 AQP5 HSPG2
4 dacryocystitis 12.5
5 osteopoikilosis and dacryocystitis 12.4
6 acute dacryocystitis 12.3
7 chronic dacryocystitis 12.3
8 acute dacryoadenitis 12.3
9 chronic dacryoadenitis 12.2
10 phlegmonous dacryocystitis 12.2
11 lacrimal duct defect 11.5
12 cellulitis 10.3
13 orbital cellulitis 10.3
14 lymphoma 10.2
15 keratoconjunctivitis 10.2
16 crohn's disease 10.1
17 conjunctivitis 10.1
18 dacryocystocele 10.1
19 aplasia of lacrimal and salivary glands 10.0 AQP5 HSPG2
20 churg-strauss syndrome 10.0
21 acanthamoeba keratitis 10.0
22 allergic angiitis 10.0
23 lymphocytic hypophysitis 10.0
24 hemometra 10.0 CD3E HSPG2
25 plasmacytoma 10.0
26 rhinitis 10.0
27 fasciitis 10.0
28 stenotrophomonas maltophilia infection 10.0
29 lacrimal apparatus disease 10.0 AQP5 HSPG2
30 myositis 10.0
31 granulomatosis with polyangiitis 10.0
32 b-cell lymphomas 10.0
33 marginal zone b-cell lymphoma 10.0
34 ptosis 10.0
35 keratoconjunctivitis sicca 10.0
36 herpes zoster 10.0
37 herpes zoster ophthalmicus 10.0
38 hepatocellular carcinoma 9.8
39 sarcoidosis 1 9.8
40 craniodiaphyseal dysplasia 9.8
41 glaucoma 3, primary congenital, a 9.8
42 myeloma, multiple 9.8
43 osteoid osteoma 9.8
44 oncocytoma 9.8
45 graft-versus-host disease 9.8
46 diffuse large b-cell lymphoma 9.8
47 thrombosis 9.8
48 endocarditis 9.8
49 microcephaly 9.8
50 erysipelas 9.8

Graphical network of the top 20 diseases related to Dacryoadenitis:



Diseases related to Dacryoadenitis

Symptoms & Phenotypes for Dacryoadenitis

Drugs & Therapeutics for Dacryoadenitis

Drugs for Dacryoadenitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antibodies
2 Immunologic Factors
3 Immunoglobulins
4 Immunoglobulin G

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation and Treatment of Patients With Corneal and External Diseases Completed NCT00008541
2 A Prospective Cohort Study of IgG4RD in China Recruiting NCT01670695

Search NIH Clinical Center for Dacryoadenitis

Cochrane evidence based reviews: dacryocystitis

Genetic Tests for Dacryoadenitis

Anatomical Context for Dacryoadenitis

MalaCards organs/tissues related to Dacryoadenitis:

41
Eye, T Cells, Thyroid, B Cells, Tonsil, Salivary Gland, Myeloid

Publications for Dacryoadenitis

Articles related to Dacryoadenitis:

(show top 50) (show all 208)
# Title Authors Year
1
Bilateral idiopathic dacryoadenitis associated with bony erosions mimicking lacrimal gland malignancy. ( 29784181 )
2018
2
Dacryoadenitis due to gonococcal conjunctivitis complicated by corneal perforation. ( 29565715 )
2018
3
Subconjunctival dendrimer-drug therapy for the treatment of dry eye in rabbits with induced autoimmune dacryoadenitis. ( 29777869 )
2018
4
Potential utility of core needle biopsy in the diagnosis of IgG4-related dacryoadenitis and sialadenitis. ( 29656682 )
2018
5
Long-Term Outcomes of Oral Anti-Tubercular Therapy in Patient with Tubercular Dacryoadenitis: A Case Series. ( 29958045 )
2018
6
Stage Classification of IgG4-related dacryoadenitis and sialadenitis by the Serum Cytokine Environment. ( 29385874 )
2018
7
Acute Dacryocystitis. ( 30067930 )
2018
8
Acute dacryocystitis complicated by orbital cellulitis and loss of vision: A case report and review of the literature. ( 30118963 )
2018
9
Metastatic hepatocellular carcinoma mimicking acute dacryocystitis. ( 30119803 )
2018
10
Pathological changes of the nasolacrimal duct in rabbit models of chronic dacryocystitis: correlation with lacrimal endoscopic findings. ( 30187128 )
2018
11
Outcome of Transcanalicular Endolaser and External Dacryocystorhinostomy in Chronic Dacryocystitis. ( 30487479 )
2018
12
Acute Vision Loss From Dacryocystitis. ( 30098149 )
2018
13
Primary tubercular dacryocystitis - a case report and review of 18 cases from the literature. ( 30142013 )
2018
14
Early Therapeutic Intervention for IgG4-related Dacryoadenitis and Sialadenitis: The Balance Between Risk of Observation Only and Therapeutic Adverse Effects. ( 30173184 )
2018
15
NOD and NOR mice exhibit comparable development of lacrimal gland secretory dysfunction but NOD mice have more severe autoimmune dacryoadenitis. ( 30201519 )
2018
16
Microbiological study of dacryocystitis in northwest of Iran. ( 30310264 )
2018
17
Type I Interferon Signaling Is Required for Dacryoadenitis in the Nonobese Diabetic Mouse Model of Sjögren Syndrome. ( 30347820 )
2018
18
Interleukin 5-producing ST2+ memory Th2 cells in IgG4-related dacryoadenitis and sialadenitis. ( 30354922 )
2018
19
Dacryocystitis and Rhinosinusitis Secondary to Sarcoidosis. ( 30444768 )
2018
20
SLE dacryoadenitis. ( 30541377 )
2018
21
A Rare Cause for Recurrent Implant-Related Inflammation of Orbit: Dacryocystitis. ( 30550443 )
2018
22
Dacryoadenitis with Ptosis and Diplopia as the Initial Presentation of Granulomatosis with Polyangiitis. ( 28883246 )
2017
23
Adipose-Derived Mesenchymal Stem Cells Reduce Lymphocytic Infiltration in a Rabbit Model of Induced Autoimmune Dacryoadenitis: Some Discussions. ( 28288268 )
2017
24
Dacryoadenitis as the Initial Presentation of a Natural Killer T-Cell Lymphoma. ( 28328558 )
2017
25
Mesenchymal stem cells for treating autoimmune dacryoadenitis. ( 28583168 )
2017
26
Sarcoidosis presenting with acute dacryoadenitis. ( 29257721 )
2017
27
Bilateral subacute lacrimal gland enlargement mimicking dacryoadenitis in a 7-year-old boy: a rare adverse effect of valproic acid (sodium valproate). ( 28359767 )
2017
28
Bilateral Infiltrative Dacryoadenitis and Granulomatous Pneumonia in an 11-Year-Old Boy: A Case Report. ( 28444655 )
2017
29
Interleukin-1 Inhibitors and Dacryoadenitis in Adult-Onset Still Disease. ( 29230477 )
2017
30
A case of concurrent silent sinus syndrome, thyroid eye disease, idiopathic orbital inflammatory syndrome, and dacryoadenitis. ( 28812921 )
2017
31
Bilateral Dacryoadenitis: Don't Forget Tuberculosis! ( 27956729 )
2017
32
Adipose-Derived Mesenchymal Stem Cells Reduce Lymphocytic Infiltration in a Rabbit Model of Induced Autoimmune Dacryoadenitis. ( 27699412 )
2016
33
First case report of isolated aspergillus dacryoadenitis. ( 27488157 )
2016
34
The pathological features of ectopic lymphoid neogenesis in idiopathic dacryoadenitis. ( 27230507 )
2016
35
Dacryoadenitis and extraocular muscle inflammation associated with contact lens-related Acanthamoeba keratitis: A case report and review of the literature. ( 27874294 )
2016
36
Acute Painful Ptosis Secondary to IgG4 Dacryoadenitis. ( 27293410 )
2016
37
Relationship between dacryoadenitis subtype of idiopathic orbital inflammatory pseudotumor and paranasal sinusitis. ( 27158618 )
2016
38
Idiopathic Dacryoadenitis: Clinical Features, Histopathology, and Treatment Outcomes. ( 26701269 )
2016
39
Bilateral dacryoadenitis as initial presentation of a locally aggressive and unresponsive limited form of orbital granulomatosis with polyangiitis. ( 27170605 )
2016
40
Dacryoadenitis associated with IgG4-related disease in an Afro-Colombian adolescent. ( 27989497 )
2016
41
Changes in Tear Film Characteristics in Patients with Idiopathic Dacryoadenitis. ( 26863039 )
2016
42
[Ophthalmoplegia without severe painful eyelid swelling in acute dacryoadenitis: a case report]. ( 26616487 )
2016
43
Lesional CD4+ IFN-I^+ cytotoxic T lymphocytes in IgG4-related dacryoadenitis and sialoadenitis. ( 27358392 )
2016
44
Long-term outcomes of powered endoscopic dacryocystorhinostomy in acute dacryocystitis. ( 25994372 )
2016
45
Reply re: "Pediatric Acute Dacryocystitis". ( 26953973 )
2016
46
Microbiology of primary acquired nasolacrimal duct obstruction: simple epiphora, acute dacryocystitis, and chronic dacryocystitis. ( 26955261 )
2016
47
Resolution of elevated circulating regulatory T cells by corticosteroids in patients with IgG4-related dacryoadenitis and sialoadenitis. ( 26385129 )
2015
48
A case of marginal zone B cell lymphoma mimicking IgG4-related dacryoadenitis and sialoadenitis. ( 25889621 )
2015
49
Immune complexome analysis of antigens in circulating immune complexes isolated from patients with IgG4-related dacryoadenitis and/or sialadenitis. ( 26166493 )
2015
50
Preferential M2 macrophages contribute to fibrosis in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. ( 25450336 )
2015

Variations for Dacryoadenitis

Expression for Dacryoadenitis

Search GEO for disease gene expression data for Dacryoadenitis.

Pathways for Dacryoadenitis

Pathways related to Dacryoadenitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.07 CD3E IL21
2 10.35 CD3E IL21

GO Terms for Dacryoadenitis

Cellular components related to Dacryoadenitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.35 AQP5 CTSZ HSPG2 PMVK VIL1
2 microvillus GO:0005902 8.62 AQP5 VIL1

Biological processes related to Dacryoadenitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein-containing complex assembly GO:0065003 8.96 CD3E VIL1
2 positive regulation of T cell proliferation GO:0042102 8.62 CD3E IL21

Sources for Dacryoadenitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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