Aliases & Classifications for Dacryocystitis

MalaCards integrated aliases for Dacryocystitis:

Name: Dacryocystitis 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:9938
ICD9CM 34 375.30
MeSH 43 D003607
NCIt 49 C34521
SNOMED-CT 67 85777005
ICD10 32 H04.30
UMLS 71 C0010930

Summaries for Dacryocystitis

Disease Ontology : 12 An acute inflammation of lacrimal passage that is characterized by inflammation of the lacrimal sac, has symptom conjunctivitis and has symptom purulent discharge.

MalaCards based summary : Dacryocystitis is related to chronic dacryocystitis and acute dacryocystitis, and has symptoms including conjunctivitis and purulent discharge. An important gene associated with Dacryocystitis is DCXR (Dicarbonyl And L-Xylulose Reductase). The drugs Ofloxacin and Levofloxacin have been mentioned in the context of this disorder. Affiliated tissues include eye, bone and b cells.

Wikipedia : 74 Dacryocystitis is an infection of the lacrimal sac, secondary to obstruction of the nasolacrimal duct at... more...

Related Diseases for Dacryocystitis

Diseases in the Dacryocystitis family:

Acute Dacryocystitis Chronic Dacryocystitis

Diseases related to Dacryocystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 151)
# Related Disease Score Top Affiliating Genes
1 chronic dacryocystitis 33.1 SRCIN1 FLNA EXT1 DCXR
2 acute dacryocystitis 32.8 EXT1 DCXR DCT CPLX3
3 dacryocystocele 30.4 FLNA DCXR
4 excessive tearing 30.1 SRCIN1 DCXR
5 osteopoikilosis and dacryocystitis 12.7
6 phlegmonous dacryocystitis 12.4
7 dacryoadenitis 11.9
8 lacrimal duct defect 11.6
9 lacrimoauriculodentodigital syndrome 11.3
10 ophthalmia neonatorum 10.8
11 cellulitis 10.6
12 orbital cellulitis 10.5
13 conjunctivitis 10.4
14 pfeiffer syndrome 10.3
15 haemophilus influenzae 10.3
16 stenotrophomonas maltophilia infection 10.3
17 cicatricial ectropion 10.3 SRCIN1 DCXR
18 entropion 10.2 SRCIN1 DCXR
19 lacrimal duct obstruction 10.2
20 rhinitis 10.2
21 internal hordeolum 10.2 SRCIN1 DCXR
22 lagophthalmos 10.1 DCXR CPLX3
23 keratitis, hereditary 10.1
24 sarcoidosis 1 10.1
25 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.1
26 lymphoma 10.1
27 sporotrichosis 10.1
28 dermoid cyst 10.1
29 cystic teratoma 10.1
30 mature teratoma 10.1
31 keratoconjunctivitis 10.1
32 hemangiopericytoma, malignant 10.0
33 lymphoma, hodgkin, classic 10.0
34 myeloma, multiple 10.0
35 lymphoma, non-hodgkin, familial 10.0
36 diffuse large b-cell lymphoma 10.0
37 meningocele 10.0
38 keratoconjunctivitis sicca 10.0
39 tularemia 10.0
40 embryonal rhabdomyosarcoma 10.0
41 rhabdomyosarcoma 10.0
42 extramedullary plasmacytoma 10.0
43 plasmacytoma 10.0
44 cervical adenitis 10.0
45 atrophic rhinitis 10.0
46 b-cell lymphoma 10.0
47 corneal ulcer 10.0
48 exophthalmos 10.0
49 fasciitis 10.0
50 encephalocele 10.0

Comorbidity relations with Dacryocystitis via Phenotypic Disease Network (PDN):


Orbital Cellulitis

Graphical network of the top 20 diseases related to Dacryocystitis:



Diseases related to Dacryocystitis

Symptoms & Phenotypes for Dacryocystitis

Symptoms:

12
  • conjunctivitis
  • purulent discharge

Drugs & Therapeutics for Dacryocystitis

Drugs for Dacryocystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ofloxacin Approved Phase 4 82419-36-1 4583
2
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
3 Antibiotics, Antitubercular Phase 4
4 Anti-Bacterial Agents Phase 4
5 Renal Agents Phase 4
6 Cytochrome P-450 Enzyme Inhibitors Phase 4
7 Ophthalmic Solutions Phase 4
8 Anti-Infective Agents Phase 4
9 Topoisomerase Inhibitors Phase 4
10 Anti-Infective Agents, Urinary Phase 4
11 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
12 Mitomycins
13 Alkylating Agents
14 Calamus

Interventional clinical trials:

(show all 12)
# Name Status NCT ID Phase Drugs
1 Phase 4 Study on Effectiveness of Topical 0.5% Levofloxacin on Reduction of Preoperative Conjunctival Flora in Patients Scheduled for Intraocular Surgery Completed NCT00491049 Phase 4 0.5% levofloxacin eye drops
2 The Study of Bacteriology and Pathogen Drug Sensitivity of Chronic Dacryocystitis Unknown status NCT03216642
3 The Microbiological Spectrum in Acute Dacryocystitis Completed NCT00349297
4 Efficacy of Mitomycin C in Endoscopic Dacryocystorhinostomy: A Systematic Review and Meta-Analysis Completed NCT01772277
5 Long Term Follow up of Nasolacrimal Intubation in Adults With Mild Epiphora Completed NCT00706251
6 Evaluation and Treatment of Corneal and External Diseases and Anterior Segment Disorders Completed NCT00008541
7 Multicenter Study About Fusarium Keratitits in Spain 2012 to 2014 Completed NCT02984904
8 Lacrimal Sac Dacryoliths (86 Samples): Chemical and Mineralogic Analyses Completed NCT01826734
9 Lacrimal Drainage Resistance Study Completed NCT01766232
10 Comparison of Endonasal-Endoscopic Dacryocystorhinostomy Versus External Dacryocystorhinostomy Recruiting NCT02993770
11 Endoscopy Assisted Probing Versus Simple Probing in Patients With Primary Congenital Nasolacrimal Duct Obstruction: A Randomized Clinical Trial Active, not recruiting NCT03242681
12 Safety and Efficacy of the Slit Stent II Lacrimal Stent for the Treatment of Nasolacrimal Duct Obstruction Not yet recruiting NCT03705000

Search NIH Clinical Center for Dacryocystitis

Genetic Tests for Dacryocystitis

Anatomical Context for Dacryocystitis

MalaCards organs/tissues related to Dacryocystitis:

40
Eye, Bone, B Cells, Skin, Thyroid, Salivary Gland, Heart

Publications for Dacryocystitis

Articles related to Dacryocystitis:

(show top 50) (show all 1085)
# Title Authors PMID Year
1
An update on endoscopic mechanical and powered dacryocystorhinostomy in acute dacryocystitis and lacrimal abscess. 61
31465822 2020
2
HPLC-DAD Analysis, Antioxidant and Protective Effects of Tunisian Rhanterium suaveolens against Acetamiprid Induced Oxidative Stress on Mice Erythrocytes. 61
31637808 2019
3
Two cases of epidemic keratoconjunctivitis-associated dacryocystitis. 61
31852315 2019
4
Shifting to very early endoscopic DCR in acute suppurative dacryocystitis. 61
31822856 2019
5
Characteristics of lacrimal passage diseases by 80-MHz ultrasound biomicroscopy: an observational study. 61
31823059 2019
6
A Review of Diagnostic and Therapeutic Dacryoendoscopy. 61
31162301 2019
7
Lacrimal sac lymphoma: A series of Japanese patients. 61
30270644 2019
8
Endoscopic DCR: A 10 Years Personal Experience. 61
31763290 2019
9
External dacryocystorhinostomy in patients with granulomatous polyangiitis. 61
31685972 2019
10
Lacrimal Drainage Anomalies in CHARGE Syndrome: Case Report and Review of Literature. 61
31593046 2019
11
Endoscopic dacryocystorhinostomy: reasons for failure. 61
31595028 2019
12
The Role of Bacterial Etiology in the Tear Duct Infections Secondary to Congenital Nasolacrimal Duct Obstructions. 61
31369500 2019
13
Endoscopic Evaluation of Lacrimal Mucosa With Indigo Carmine Stain. 61
31567915 2019
14
Bilateral dacryocystitis complicated by unilateral retrobulbar abscess in a five-week-old infant. 61
31509038 2019
15
[Masquerade lacrimal duct stenosis: prevalence of lacrimal sac tumors]. 61
31520115 2019
16
Paediatric orbital and periorbital infections. 61
31261188 2019
17
Dermoid cyst simulating recurrent dacryocystitis in a toddler. 61
31358169 2019
18
Dacryocystosclerotherapy as an alternative to dacryocystectomy. 61
30424707 2019
19
Primary tubercular dacryocystitis - a case report and review of 18 cases from the literature. 61
30142013 2019
20
Conservative management of congenital dacryocystocele: resolution and complications. 61
31358138 2019
21
Awake bedside nasal endoscopy for primary management of neonatal dacryocystoceles with intranasal cysts. 61
31085463 2019
22
Relationship Between Lacrimal Bone Thickness and Lacrimal Sac in Chronic Dacryocystitis. 61
31469733 2019
23
External dacryocystorhinostomy conventional surgery versus Pawar implant: A comparative study. 61
31238430 2019
24
Lymphoproliferative tumors involving the lacrimal drainage system: a major review. 61
31267826 2019
25
Lacrimal Sac Sebaceous Carcinoma. 61
30921057 2019
26
Congenital Dacryocystocele: A Major Review. 61
30601463 2019
27
[Pediatric acute dacryocystitis due to frontoethmoidal mucocele]. 61
31065761 2019
28
A Rare Complication of Oropharyngeal Tularemia: Dacryocystitis 61
31245979 2019
29
A Rare Cause for Recurrent Implant-Related Inflammation of Orbit: Dacryocystitis. 61
30550443 2019
30
Chronic dacryocystitis caused by sarcoidosis. 61
30558969 2019
31
Outcome of External Dacryocystorhinostomy and Monocanalicular Intubation in Patients with Total Obstruction of One Canalicus. 61
30977323 2019
32
Surfactant proteins: Role in lacrimal drainage disorders. 61
30798912 2019
33
Clinical significance of ocular manifestations in granulomatosis with polyangiitis: association with sinonasal involvement and damage. 61
30706192 2019
34
Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the lacrimal drainage system in two pediatric patients. 61
30862184 2019
35
Ultrasonography-guided removal of plant-based foreign bodies from the lacrimal sac in four dogs. 61
30836969 2019
36
Efficacy of nasal endoscopic dacryocystorhinostomy for chronic dacryocystitis: A systematic review protocol of randomized controlled trial. 61
30896635 2019
37
The microbiologic profile of dacryocystitis. 61
29750587 2019
38
Post-traumatic endophthalmitis caused by Nocardia nova. 61
30886723 2019
39
Ocular Surface Disease of Rabbits. 61
30454757 2019
40
Dacryocystitis and Rhinosinusitis Secondary to Sarcoidosis. 61
30444768 2019
41
Nasolacrimal Sac Diverticulum: A Case Series and Literature Review. 61
29952932 2019
42
IgG4-related dacryocystitis and aortitis: A new association. 61
30642193 2019
43
Comparative study of the clinical profile of chronic dacryocystitis and chronic rhinosinusitis after external dacryocystorhinostomy. 61
31409965 2019
44
High Prevalence of Biofilm-Forming MRSA in the Conjunctival Flora in Chronic Dacryocystitis. 61
30794029 2019
45
Cultures of Proximal and Distal Segments of Silicone Tubes After Dacryocystorhinostomy. 61
29927881 2019
46
A case report on complete cure of recurrent primary canaliculitis by 4-snip punctoplasty and canalicular curettage. 61
30544448 2018
47
Dacryoendoscopy-assisted nasal endoscopic marsupialization for congenital dacryocystocele. 61
30368393 2018
48
Improving the Results of Endonasal Dacryocystorhinostomy with Mitomycin C Application: A Prospective Case-Control Study. 61
30464901 2018
49
Pathological changes of the nasolacrimal duct in rabbit models of chronic dacryocystitis: correlation with lacrimal endoscopic findings. 61
30187128 2018
50
Dacryocystitis mimicking erysipelas due to a giant dacryolith. 61
29655289 2018

Variations for Dacryocystitis

Expression for Dacryocystitis

Search GEO for disease gene expression data for Dacryocystitis.

Pathways for Dacryocystitis

GO Terms for Dacryocystitis

Cellular components related to Dacryocystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.1 FLNA DEFB1 DCXR CPQ BPI AZU1
2 extrinsic component of membrane GO:0019898 8.96 DEFB1 AZU1

Biological processes related to Dacryocystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.43 DEFB1 BPI AZU1
2 calcium-mediated signaling using intracellular calcium source GO:0035584 9.16 DEFB1 AZU1
3 defense response to Gram-negative bacterium GO:0050829 9.13 DEFB1 BPI AZU1
4 antimicrobial humoral response GO:0019730 8.8 DEFB1 BPI AZU1

Sources for Dacryocystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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