MCID: DPN002
MIFTS: 21

Deep Angioma

Categories: Cancer diseases

Aliases & Classifications for Deep Angioma

MalaCards integrated aliases for Deep Angioma:

Name: Deep Angioma 12 15
Deep Hemangioma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:469
NCIt 50 C6555
UMLS 73 C1333265

Summaries for Deep Angioma

MalaCards based summary : Deep Angioma, also known as deep hemangioma, is related to vulvar syringoma and lung leiomyoma. An important gene associated with Deep Angioma is JMJD6 (Arginine Demethylase And Lysine Hydroxylase), and among its related pathways/superpathways is Photodynamic therapy-induced HIF-1 survival signaling. Related phenotypes are homeostasis/metabolism and cardiovascular system

Related Diseases for Deep Angioma

Diseases related to Deep Angioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 108)
# Related Disease Score Top Affiliating Genes
1 vulvar syringoma 10.6 ESR1 PGR
2 lung leiomyoma 10.6 ESR1 PGR
3 vestibular gland benign neoplasm 10.6 ESR1 PGR
4 bartholin's gland adenoma 10.6 ESR1 PGR
5 glassy cell carcinoma of the cervix 10.6 ESR1 PGR
6 vulvar benign neoplasm 10.6 ESR1 PGR
7 vulvar leiomyoma 10.6 ESR1 PGR
8 melanotic neurilemmoma 10.6 CD34 TYR
9 predominantly cortical thymoma 10.6 ESR1 PGR
10 diffuse meningeal melanocytosis 10.6 CD34 TYR
11 breast medullary carcinoma 10.6 ESR1 PGR
12 breast scirrhous carcinoma 10.6 ESR1 PGR
13 progesterone resistance 10.5 ESR1 PGR
14 progesterone-receptor positive breast cancer 10.5 ESR1 PGR
15 cribriform carcinoma 10.5 ESR1 PGR
16 oncocytic breast carcinoma 10.5 ESR1 PGR
17 endometrial squamous cell carcinoma 10.5 ESR1 PGR
18 gastric signet ring cell adenocarcinoma 10.5 ESR1 PGR
19 endometrial mucinous adenocarcinoma 10.5 ESR1 PGR
20 adenoid basal cell carcinoma 10.5 ESR1 PGR
21 apocrine adenocarcinoma 10.5 ESR1 PGR
22 gender identity disorder 10.5 ESR1 PGR
23 bartholin's gland benign neoplasm 10.5 ESR1 PGR
24 synchronous bilateral breast carcinoma 10.5 ESR1 PGR
25 breast adenoid cystic carcinoma 10.5 ESR1 PGR
26 spleen angiosarcoma 10.5 CD34 VWF
27 cervical carcinosarcoma 10.5 ESR1 PGR
28 estrogen excess 10.5 ESR1 PGR
29 glycogen-rich clear cell breast carcinoma 10.5 ESR1 PGR
30 mammographic density 10.5 ESR1 PGR
31 retinitis pigmentosa 47 10.5 ESR1 PGR
32 prostate stromal sarcoma 10.5 CD34 PGR
33 uterine corpus cancer 10.5 ESR1 PGR
34 adenomyosis 10.5 ESR1 PGR
35 kaposiform hemangioendothelioma 10.5 CD34 VWF
36 retinitis pigmentosa 20 10.5 ESR1 PGR
37 luminal breast carcinoma 10.5 ESR1 PGR
38 vulvar dystrophy 10.5 CD34 PGR
39 lung meningioma 10.5 CD34 PGR
40 adenosarcoma 10.5 ESR1 PGR
41 cervical clear cell adenocarcinoma 10.5 ESR1 PGR
42 endometriosis of ovary 10.5 ESR1 PGR
43 inflammatory breast carcinoma 10.5 ESR1 PGR
44 mixed cell type cancer 10.5 ESR1 PGR
45 lipid-rich carcinoma 10.5 ESR1 PGR
46 uterine benign neoplasm 10.4 ESR1 PGR
47 reproductive organ benign neoplasm 10.4 ESR1 PGR
48 smooth muscle tumor 10.4 ESR1 PGR
49 pancreatic mucinous cystadenoma 10.4 ESR1 PGR
50 lymphangiosarcoma 10.4 CD34 VWF

Graphical network of the top 20 diseases related to Deep Angioma:



Diseases related to Deep Angioma

Symptoms & Phenotypes for Deep Angioma

MGI Mouse Phenotypes related to Deep Angioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.81 JMJD6 PGR SLC2A1 TYR VWF ANGPT1
2 cardiovascular system MP:0005385 9.8 JMJD6 PGR TYR VWF ANGPT1 ANXA2
3 immune system MP:0005387 9.5 ESR1 JMJD6 PGR TYR VWF ANGPT1
4 no phenotypic analysis MP:0003012 9.1 JMJD6 PGR SLC2A1 TYR VWF ESR1

Drugs & Therapeutics for Deep Angioma

Search Clinical Trials , NIH Clinical Center for Deep Angioma

Genetic Tests for Deep Angioma

Anatomical Context for Deep Angioma

Publications for Deep Angioma

Variations for Deep Angioma

Expression for Deep Angioma

Search GEO for disease gene expression data for Deep Angioma.

Pathways for Deep Angioma

Pathways related to Deep Angioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.19 ANGPT1 SLC2A1

GO Terms for Deep Angioma

Cellular components related to Deep Angioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane raft GO:0045121 9.13 ANGPT1 ANXA2 SLC2A1
2 melanosome GO:0042470 8.8 ANXA2 SLC2A1 TYR

Biological processes related to Deep Angioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.43 CD34 ESR1 PGR
2 sprouting angiogenesis GO:0002040 9.16 ANGPT1 JMJD6
3 cell-substrate adhesion GO:0031589 8.96 ANGPT1 VWF
4 paracrine signaling GO:0038001 8.62 CD34 PGR

Molecular functions related to Deep Angioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear receptor activity GO:0004879 9.16 ESR1 PGR
2 identical protein binding GO:0042802 9.1 ANXA2 ESR1 JMJD6 PGR SLC2A1 VWF
3 steroid binding GO:0005496 8.96 ESR1 PGR

Sources for Deep Angioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....