MCID: DPL001
MIFTS: 23

Deep Leiomyoma

Categories: Cancer diseases

Aliases & Classifications for Deep Leiomyoma

MalaCards integrated aliases for Deep Leiomyoma:

Name: Deep Leiomyoma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:5128
NCIt 50 C6512
UMLS 70 C1333266

Summaries for Deep Leiomyoma

Disease Ontology : 12 A leiomyoma that is located in deep soft tissue.

MalaCards based summary : Deep Leiomyoma is related to leiomyoma and esophageal adenoid cystic carcinoma. An important gene associated with Deep Leiomyoma is CD177 (CD177 Molecule), and among its related pathways/superpathways are Development Angiotensin activation of ERK and Cardiac Progenitor Differentiation. Affiliated tissues include deep soft tissue, breast and small intestine.

Related Diseases for Deep Leiomyoma

Diseases related to Deep Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 165)
# Related Disease Score Top Affiliating Genes
1 leiomyoma 29.2 PDGFRA KIT CD34
2 esophageal adenoid cystic carcinoma 10.1 KIT ANO1
3 gastric hemangioma 10.1 KIT ANO1
4 urethra leiomyoma 10.1 KIT CALD1
5 prostate embryonal rhabdomyosarcoma 10.1 KIT CALD1
6 mucinous stomach adenocarcinoma 10.1 KIT ANO1
7 active peptic ulcer disease 10.1 KIT ANO1
8 reticular perineurioma 10.1 PDGFRA KIT
9 laryngeal small cell carcinoma 10.1 PDGFRA KIT
10 uterus leiomyosarcoma 10.1 KIT CALD1
11 pulmonary vein stenosis 10.1 PDGFRA KIT
12 lung combined type small cell carcinoma 10.1 GFAP CALD1
13 myeloid and lymphoid neoplasms associated with pdgfra rearrangement 10.0 PDGFRA KIT
14 hypereosinophilic syndrome, idiopathic 10.0 PDGFRA KIT
15 sm-ahnmd 10.0 PDGFRA KIT
16 endometrial small cell carcinoma 10.0 PDGFRA KIT
17 perivascular epithelioid cell tumor 10.0 KIT CALD1
18 perineurioma 10.0 KIT GFAP
19 carney triad 10.0 PDGFRA KIT
20 fibrosarcoma of bone 10.0 PDGFRA KIT
21 myelodysplastic/myeloproliferative neoplasm 10.0 PDGFRA KIT
22 plexiform neurofibroma 10.0 PDGFRA KIT
23 parasagittal meningioma 10.0 CD34 ANO1
24 glomangioma 10.0 CD34 CALD1
25 mixed glioma 10.0 PDGFRA GFAP
26 chronic eosinophilic leukemia 10.0 PDGFRA KIT
27 intravascular angioleiomyoma 10.0 CD34 CALD1
28 pulmonary artery leiomyosarcoma 9.9 CD34 ANO1
29 breast myofibroblastoma 9.9 CD34 CALD1
30 large cell neuroendocrine carcinoma 9.9 PDGFRA KIT
31 pulmonary vein leiomyosarcoma 9.9 CD34 CALD1
32 glomangiomyoma 9.9 CD34 CALD1
33 vulvar leiomyosarcoma 9.9 CD34 CALD1
34 peritoneal benign neoplasm 9.9 CD34 CALD1
35 glomangiosarcoma 9.9 CD34 CALD1
36 adult fibrosarcoma 9.9 CD34 CALD1
37 cervical polyp 9.9 CD34 CALD1
38 testicular fibroma 9.9 CD34 CALD1
39 intravenous leiomyomatosis 9.9 CD34 CALD1
40 sarcomatoid squamous cell skin carcinoma 9.9 CD34 CALD1
41 congenital granular cell tumor 9.9 CD34 CALD1
42 subungual glomus tumor 9.9 CD34 CALD1
43 glomus tumor 9.9 CD34 CALD1
44 spinal cord sarcoma 9.9 KIT CD34
45 vulvar leiomyoma 9.9 CD34 CALD1
46 cystic teratoma 9.9 KIT GFAP
47 infiltrating angiolipoma 9.9 CD34 CALD1
48 gallbladder leiomyoma 9.9 KIT CD34
49 epithelioid cell synovial sarcoma 9.9 CD34 ANO1
50 angiolipoma 9.9 CD34 CALD1

Graphical network of the top 20 diseases related to Deep Leiomyoma:



Diseases related to Deep Leiomyoma

Symptoms & Phenotypes for Deep Leiomyoma

Drugs & Therapeutics for Deep Leiomyoma

Search Clinical Trials , NIH Clinical Center for Deep Leiomyoma

Genetic Tests for Deep Leiomyoma

Anatomical Context for Deep Leiomyoma

The Foundational Model of Anatomy Ontology organs/tissues related to Deep Leiomyoma:

19
Deep Soft Tissue

MalaCards organs/tissues related to Deep Leiomyoma:

40
Breast, Small Intestine, Liver, Myeloid, Heart, Colon, Lung

Publications for Deep Leiomyoma

Articles related to Deep Leiomyoma:

# Title Authors PMID Year
1
Superficial leiomyomas of the gastrointestinal tract with interstitial cells of Cajal. 61
26884872 2015
2
A bizarre giant leiomyoma. 61
11357051 2001
3
DEEP LEIOMYOMA OF AN EXTREMITY. 61
14275173 1965

Variations for Deep Leiomyoma

Expression for Deep Leiomyoma

Search GEO for disease gene expression data for Deep Leiomyoma.

Pathways for Deep Leiomyoma

Pathways related to Deep Leiomyoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.19 PDGFRA KIT CALD1
2 10.88 PDGFRA KIT
3
Show member pathways
10.67 PDGFRA KIT
4
Show member pathways
10.15 PDGFRA KIT

GO Terms for Deep Leiomyoma

Cellular components related to Deep Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.8 PDGFRA KIT CD34

Biological processes related to Deep Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hematopoietic progenitor cell differentiation GO:0002244 9.16 PDGFRA KIT
2 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 8.96 PDGFRA KIT
3 positive regulation of phospholipase C activity GO:0010863 8.62 PDGFRA KIT

Molecular functions related to Deep Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane receptor protein tyrosine kinase activity GO:0004714 8.62 PDGFRA KIT

Sources for Deep Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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