MCID: DMD001
MIFTS: 25

Demodicidosis

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Demodicidosis

MalaCards integrated aliases for Demodicidosis:

Name: Demodicidosis 54 60
Infestation by Demodex 74
Demodicosis 60

Classifications:

Orphanet: 60  
Rare infectious diseases


External Ids:

ICD10 via Orphanet 35 B88.0
UMLS via Orphanet 75 C3854478
Orphanet 60 ORPHA283
UMLS 74 C0392666

Summaries for Demodicidosis

MalaCards based summary : Demodicidosis, also known as infestation by demodex, is related to rosacea and leukemia. The drugs Chloramphenicol and Formaldehyde have been mentioned in the context of this disorder. Affiliated tissues include skin and eye.

Wikipedia : 77 Mange /ˈmeɪndʒ/ is a type of skin disease caused by parasitic mites. Because mites also infect plants,... more...

Related Diseases for Demodicidosis

Diseases related to Demodicidosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 28)
# Related Disease Score Top Affiliating Genes
1 rosacea 10.6
2 leukemia 10.2
3 alopecia 10.1
4 leukemia, acute lymphoblastic 10.1
5 graft-versus-host disease 10.1
6 lymphocytic leukemia 10.1
7 acquired immunodeficiency syndrome 10.1
8 granulomatous rosacea 10.1
9 pelger-huet anomaly 10.0
10 langerhans cell histiocytosis 10.0
11 ehrlichiosis 10.0
12 blepharoconjunctivitis 10.0
13 histiocytosis 10.0
14 pyoderma 10.0
15 dermatophytosis 10.0
16 babesiosis 10.0
17 cytokine deficiency 10.0
18 acute lymphoblastic leukemia, childhood 10.0
19 hematopoietic stem cell transplantation 10.0
20 pemphigus foliaceus 10.0
21 lymphoma 10.0
22 tinea favosa 10.0
23 psoriasis 10.0
24 pemphigus 10.0
25 otitis externa 10.0
26 meibomian cyst 10.0
27 acute graft versus host disease 10.0
28 grover's disease 10.0

Graphical network of the top 20 diseases related to Demodicidosis:



Diseases related to Demodicidosis

Symptoms & Phenotypes for Demodicidosis

Drugs & Therapeutics for Demodicidosis

Drugs for Demodicidosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Chloramphenicol Approved, Vet_approved Phase 4 56-75-7 5959 298
2
Formaldehyde Approved, Vet_approved Phase 4 50-00-0 712
3
Fusidic Acid Approved, Investigational Phase 4 6990-06-3 3000226
4
Permethrin Approved, Investigational Phase 4 52645-53-1 40326
5
Chloramphenicol succinate Approved Phase 4 3544-94-3
6 Anti-Infective Agents Phase 4,Phase 3
7 Pharmaceutical Solutions Phase 4
8 Ophthalmic Solutions Phase 4
9 Butylated Hydroxytoluene Phase 4
10 Anti-Bacterial Agents Phase 4
11
Ivermectin Approved, Investigational, Vet_approved Phase 3 70288-86-7 6474909
12 Antiparasitic Agents Phase 3
13
Tea tree oil Approved Phase 1
14 Tea Phase 1
15 Tea Tree Phase 1
16
Triamcinolone Approved, Vet_approved 124-94-7 31307
17 Triamcinolone hexacetonide
18 Triamcinolone diacetate
19 triamcinolone acetonide
20 Antioxidants

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Efficacy of Permethrin 5%, Fusidic Acid 1% and Synthomycine 5% for Demodex - Blepharitis Enrolling by invitation NCT03105505 Phase 4 Permethrin 5%;Synthomycine 5%;Fusidic Acid 1% M/R Eye Drops
2 Topical 0.5% Ivermectin Cream for Treatment of Demodicidosis Unknown status NCT02036229 Phase 3 ivermectin cream 0.5%
3 Demodex Blepharitis Treatment Study Completed NCT01647217 Phase 1 Terpinen-4-ol
4 Demodex Density, Immune Response and Oxidative Stress in Rosacea Patients Unknown status NCT02556827
5 PCR (Polymerase Chain Reaction) Assay for Diagnosis of Sarcoptes Scabiei Completed NCT02254564
6 Ultrahigh-resolution Optical Coherence Tomography Imaging of the Anterior Eye Segment Structures Enrolling by invitation NCT03461978 Not Applicable
7 The Effect of Eyelid Margin Debridement on Contact Lens Discomfort Not yet recruiting NCT03311204 Not Applicable

Search NIH Clinical Center for Demodicidosis

Genetic Tests for Demodicidosis

Anatomical Context for Demodicidosis

MalaCards organs/tissues related to Demodicidosis:

42
Skin, Eye

Publications for Demodicidosis

Articles related to Demodicidosis:

(show top 50) (show all 67)
# Title Authors Year
1
Demodicidosis of the nipple. ( 30587280 )
2019
2
Demodicidosis Accompanying Acute Cutaneous Graft-Versus-Host Disease after Allogeneic Stem Cell Transplantation ( 29983401 )
2018
3
Usefulness of dermoscopy in the diagnosis and monitoring treatment of demodicidosis. ( 28243492 )
2017
4
Rosacea and demodicidosis associated with gain-of-function mutation in STAT1. ( 28622416 )
2017
5
Clues to Facial Demodicidosis: A Case Illustration. ( 27512199 )
2016
6
Unilateral Demodicidosis of Face Mimicking Hansens Disease. ( 28326184 )
2016
7
Hypothesis of demodicidosis rosacea flushing etiopathogenesis. ( 25683389 )
2015
8
Chronic lymphocytic lymphoma presenting with recurrent demodicidosis. ( 25707323 )
2015
9
Ocular demodicidosis as a risk factor of adult recurrent chalazion. ( 23873491 )
2014
10
Demodicidosis on the arms of a patient with pemphigus foliaceus. ( 25128143 )
2014
11
Demodicidosis associated with psoriasis therapy--two case reports. ( 23905976 )
2013
12
Demodicidosis: an uncommon erythema after cranio-maxillofacial surgery. ( 23099109 )
2013
13
Demodicidosis simulating acute graft-versus-host disease after allogeneic stem cell transplantation in one patient with acute lymphoblastic leukemia. ( 22487272 )
2012
14
Facial demodicidosis: a diagnostic challenge. ( 22470219 )
2012
15
Crusted rosacea-like demodicidosis in an HIV-positive female. ( 21920237 )
2011
16
Dermoscopy as a diagnostic tool in demodicidosis. ( 20931672 )
2010
17
Otitis externa and myringitis due to demodicidosis. ( 19588062 )
2009
18
Demodicidosis as a cause of facial eruption developing early after allogeneic hematopoietic stem cell transplantation. ( 18783387 )
2008
19
Rosacea-like demodicidosis. ( 19022195 )
2008
20
Demodicidosis as spinulosis of the face: a therapeutic challenge. ( 17243980 )
2007
21
Scalp demodicidosis mimicking favus in a 6-year-old boy. ( 17637363 )
2007
22
Pimecrolimus-induced rosacea-like demodicidosis. ( 17910727 )
2007
23
Granulomatous rosacea-like demodicidosis. ( 18319006 )
2007
24
Plaque-forming demodicidosis. ( 15692519 )
2005
25
Demodicidosis of the nipple. ( 15868647 )
2005
26
Demodicidosis in scalp rosacea? ( 15115525 )
2004
27
Rosacea-like demodicidosis in an immunocompromised child. ( 12558842 )
2003
28
Demodicidosis in a child with xantholeukaemia associated with type 1 neurofibromatosis. ( 12804999 )
2003
29
High incidence of demodicidosis in eyelid basal cell carcinomas. ( 12839614 )
2003
30
Eucalyptus globulus (camphor oil) in the treatment of human demodicidosis. ( 12512812 )
2002
31
Demodicidosis revisited. ( 12013194 )
2002
32
Rosacea-like demodicidosis associated with acquired immunodeficiency syndrome. ( 11167695 )
2001
33
Treatment of rosacea-like demodicidosis with oral ivermectin and topical permethrin cream. ( 10534645 )
1999
34
An unusual demodicidosis manifestation in a patient with AIDS. ( 9448221 )
1998
35
Unilateral demodicidosis. ( 9649702 )
1998
36
Spinulosis of the face as a manifestation of demodicidosis. ( 9666844 )
1998
37
Demodicidosis in immunocompetent young children: report of eight cases. ( 9407170 )
1997
38
Demodicidosis in an immunodeficient child. ( 9192417 )
1997
39
Demodicidosis in childhood acute lymphoblastic leukemia; an opportunistic infection occurring with immunosuppression. ( 7472831 )
1995
40
Demodicidosis or rosacea: what did we treat? ( 7547401 )
1995
41
Unusual manifestation of demodicidosis in a child. ( 8270344 )
1993
42
Demodicidosis in a child with leukemia. ( 1469129 )
1992
43
A demodectic eruption (demodicidosis) of the face: case report. ( 1732495 )
1992
44
Topical steroid induced chronic demodicidosis. ( 1711556 )
1991
45
Papulonodular demodicidosis associated with acquired immunodeficiency syndrome. ( 2915054 )
1989
46
Rosacea and rosacea-like demodicidosis. ( 2952614 )
1987
47
Demodicidosis mimicking granulomatous rosacea and transient acantholytic dermatosis (Grover's disease). ( 2958377 )
1987
48
Demodicidosis in livestock in West Bengal (India). ( 3836214 )
1985
49
Demodicidosis in laboratory rats (Rattus norvegicus). ( 7253551 )
1981
50
Demodicidosis Involving Human Face. ( 28223595 )
1979

Variations for Demodicidosis

Expression for Demodicidosis

Search GEO for disease gene expression data for Demodicidosis.

Pathways for Demodicidosis

GO Terms for Demodicidosis

Sources for Demodicidosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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