MCID: DND003
MIFTS: 26

Dendritic Cell Thymoma

Categories: Blood diseases, Cancer diseases, Endocrine diseases, Immune diseases

Aliases & Classifications for Dendritic Cell Thymoma

MalaCards integrated aliases for Dendritic Cell Thymoma:

Name: Dendritic Cell Thymoma 12 15
Epithelioid Thymoma 12
Type B Thymoma 71

Classifications:



External Ids:

Disease Ontology 12 DOID:3282
NCIt 49 C7114
UMLS 71 C1328042

Summaries for Dendritic Cell Thymoma

MalaCards based summary : Dendritic Cell Thymoma, also known as epithelioid thymoma, is related to thymus clear cell carcinoma and verruciform xanthoma of skin. An important gene associated with Dendritic Cell Thymoma is CD5 (CD5 Molecule), and among its related pathways/superpathways are Tight junction and Amoebiasis. Affiliated tissues include thymus, skin and t cells.

Related Diseases for Dendritic Cell Thymoma

Diseases related to Dendritic Cell Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 thymus clear cell carcinoma 10.4 TTN CD5
2 verruciform xanthoma of skin 10.2 CD1E CD1A
3 multifocal motor neuropathy 10.2 CD1E CD1A
4 interstitial pneumonitis, desquamative, familial 10.2 CD1E CD1A
5 thymoma 10.2 TTN CD5 AIRE
6 thymus lipoma 10.2 CD1B CD1A
7 immune system organ benign neoplasm 10.2 CD1B CD1A
8 parapsoriasis 10.1 CD5 CD4
9 combined thymoma 10.1 CD5 CD4
10 malignant histiocytosis 10.1 CD1E CD1A
11 cardiomyopathy, familial hypertrophic, 9 10.1 TTN CD4
12 wissler's syndrome 10.1 CD4 AIRE
13 autoimmune peripheral neuropathy 10.1 CD4 AIRE
14 angular cheilitis 10.0 CD4 AIRE
15 t-cell adult acute lymphocytic leukemia 10.0 CD5 CD4
16 adult acute lymphocytic leukemia 10.0 CD5 CD4
17 esophageal candidiasis 10.0 CD4 AIRE
18 central nervous system hematologic cancer 10.0 CD5 CD4
19 anal spasm 10.0 CD4 AIRE
20 autoimmune disease of blood 10.0 CD5 CD4
21 alopecia universalis congenita 10.0 CD4 AIRE
22 pityriasis rosea 10.0 CD4 CD1E
23 anemia, autoimmune hemolytic 10.0 CD5 CD4
24 cheilitis 10.0 CD4 CD1A
25 oral hairy leukoplakia 10.0 CD4 CD1A
26 plasma protein metabolism disease 10.0 CD5 CD4
27 granulomatous dermatitis 10.0 CD4 CD1B
28 tuberculoid leprosy 9.9 CD4 CD1B
29 malignant histiocytic disease 9.9 CD1E CD1B CD1A
30 mycobacterium malmoense 9.9 CD1E CD1B CD1A
31 predominantly cortical thymoma 9.9 CHRNA1 CD1E AIRE
32 encapsulated thymoma 9.9 CD1E CD1B CD1A
33 central nervous system sarcoma 9.9 CD1E CD1B CD1A
34 lichen nitidus 9.9 CD1E CD1B CD1A
35 precursor lymphoblastic lymphoma/leukemia 9.9 CD1E CD1B CD1A
36 precursor t-lymphoblastic lymphoma/leukemia 9.9 CD1E CD1B CD1A
37 rhinoscleroma 9.9 CD1E CD1B CD1A
38 myasthenia gravis 9.9 TTN CHRNA1 AIRE
39 reticulohistiocytic granuloma 9.9 CD1E CD1B CD1A
40 langerhans cell sarcoma 9.9 CD1E CD1B CD1A
41 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 9.9 CD4 AIRE
42 interdigitating dendritic cell sarcoma 9.9 CD1E CD1B CD1A
43 orbital cancer 9.9 CD1E CD1B CD1A
44 balloon cell malignant melanoma 9.9 CD1E CD1B CD1A
45 granuloma annulare 9.9 CD1E CD1B CD1A
46 inflamed seborrheic keratosis 9.9 CD1E CD1B CD1A
47 histiocytic and dendritic cell cancer 9.9 CD1E CD1B CD1A
48 non-langerhans-cell histiocytosis 9.9 CD1E CD1B CD1A
49 adult xanthogranuloma 9.9 CD1E CD1B CD1A
50 central epithelioid sarcoma 9.9 CD1E CD1B CD1A

Graphical network of the top 20 diseases related to Dendritic Cell Thymoma:



Diseases related to Dendritic Cell Thymoma

Symptoms & Phenotypes for Dendritic Cell Thymoma

Drugs & Therapeutics for Dendritic Cell Thymoma

Search Clinical Trials , NIH Clinical Center for Dendritic Cell Thymoma

Genetic Tests for Dendritic Cell Thymoma

Anatomical Context for Dendritic Cell Thymoma

MalaCards organs/tissues related to Dendritic Cell Thymoma:

40
Thymus, Skin, T Cells, Lymph Node, Bone

Publications for Dendritic Cell Thymoma

Articles related to Dendritic Cell Thymoma:

(show all 14)
# Title Authors PMID Year
1
Distinct clinical characteristics of paraneoplastic optic neuropathy. 61
30021813 2019
2
[Thymoma in a patient with klinefelter syndrome. Case report]. 61
31344216 2019
3
Drop Metastasis of Type B Thymoma 5 Years After Resection. 61
30602412 2018
4
PD-L1 immuno-expression assay in thymomas: Study of 84 cases and review of literature. 61
29661720 2018
5
Multimodality treatment of stage II thymic tumours. 61
28932541 2017
6
Expression of cathepsins V and S in thymic epithelial tumors. 61
27771373 2017
7
Thymoma masquerading as transfusion dependent anemia. 61
28144099 2016
8
Fine-needle aspiration biopsy for the diagnosis of metastatic type B thymoma to lymph nodes: a case report. 61
23456993 2014
9
Expression of c-Jun, p73, Casp9, and N-ras in thymic epithelial tumors: relationship with the current WHO classification systems. 61
22974165 2012
10
Diagnosis and subclassification of thymoma by minimally invasive fine needle aspiration directed by endobronchial ultrasound: a review and discussion of four cases. 61
22805512 2012
11
Proteome analysis and tissue array for profiling protein markers associated with type B thymoma subclassification. 61
22932072 2012
12
Expression of proteasome subunit β5t in thymic epithelial tumors. 61
21836487 2011
13
Type B thymoma: is prognosis predicted only by World Health Organization classification? 61
20038470 2010
14
Diagnostic utility of thymic epithelial markers CD205 (DEC205) and Foxn1 in thymic epithelial neoplasms. 61
17592270 2007

Variations for Dendritic Cell Thymoma

Expression for Dendritic Cell Thymoma

Search GEO for disease gene expression data for Dendritic Cell Thymoma.

Pathways for Dendritic Cell Thymoma

Pathways related to Dendritic Cell Thymoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.56 CD1E CD1B CD1A
2 11.14 CD1E CD1B CD1A
3 11.02 CD5 CD4 CD1E CD1B CD1A
4 10.84 CD4 AIRE

GO Terms for Dendritic Cell Thymoma

Cellular components related to Dendritic Cell Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.46 CHRNA1 CD58 CD4 CD1B
2 integral component of plasma membrane GO:0005887 9.43 CHRNA1 CD58 CD5 CD4 CD1E CD1A
3 external side of plasma membrane GO:0009897 9.02 CD5 CD4 CD1E CD1B CD1A

Biological processes related to Dendritic Cell Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.67 CD4 CD1E CD1B CD1A
2 immune response GO:0006955 9.65 CD4 CD1E CD1B CD1A AIRE
3 adaptive immune response GO:0002250 9.62 CD4 CD1E CD1B CD1A
4 positive regulation of T cell mediated cytotoxicity GO:0001916 9.33 CD1E CD1B CD1A
5 antigen processing and presentation, exogenous lipid antigen via MHC class Ib GO:0048007 9.13 CD1E CD1B CD1A
6 antigen processing and presentation, endogenous lipid antigen via MHC class Ib GO:0048006 8.8 CD1E CD1B CD1A

Molecular functions related to Dendritic Cell Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 9.43 CHRNA1 CD5 CD4
2 lipopeptide binding GO:0071723 9.33 CD1E CD1B CD1A
3 exogenous lipid antigen binding GO:0030884 9.13 CD1E CD1B CD1A
4 endogenous lipid antigen binding GO:0030883 8.8 CD1E CD1B CD1A

Sources for Dendritic Cell Thymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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