MCID: DND003
MIFTS: 24

Dendritic Cell Thymoma

Categories: Blood diseases, Cancer diseases, Immune diseases

Aliases & Classifications for Dendritic Cell Thymoma

MalaCards integrated aliases for Dendritic Cell Thymoma:

Name: Dendritic Cell Thymoma 12 15
Epithelioid Thymoma 12
Type B Thymoma 71

Classifications:



External Ids:

Disease Ontology 12 DOID:3282
NCIt 49 C7114
UMLS 71 C1328042

Summaries for Dendritic Cell Thymoma

MalaCards based summary : Dendritic Cell Thymoma, also known as epithelioid thymoma, is related to thymus clear cell carcinoma and thyrotoxic exophthalmos. An important gene associated with Dendritic Cell Thymoma is CD5 (CD5 Molecule), and among its related pathways/superpathways are Tight junction and Amoebiasis. Affiliated tissues include lymph node.

Related Diseases for Dendritic Cell Thymoma

Diseases related to Dendritic Cell Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 115)
# Related Disease Score Top Affiliating Genes
1 thymus clear cell carcinoma 10.4 TTN CD5
2 thyrotoxic exophthalmos 10.4 TG CD5
3 papillary thymic adenocarcinoma 10.4 TG CD5
4 endocrine exophthalmos 10.4 TG CD5
5 parapsoriasis 10.3 CD5 CD4
6 eye lymphoma 10.3 CD5 CD4
7 wissler-fanconi syndrome 10.3 CD4 AIRE
8 cardiomyopathy, familial hypertrophic, 9 10.3 TTN CD4
9 angular cheilitis 10.3 CD4 AIRE
10 autoimmune peripheral neuropathy 10.3 CD4 AIRE
11 esophageal candidiasis 10.3 CD4 AIRE
12 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.2 TG AIRE
13 subacute lymphocytic thyroiditis 10.2 TG CD4
14 granulomatous orchitis 10.2 CD1E AIRE
15 t-cell adult acute lymphocytic leukemia 10.2 CD5 CD4
16 good syndrome 10.2 CD4 AIRE
17 adrenal cortical hypofunction 10.2 TG AIRE
18 central nervous system hematologic cancer 10.2 CD5 CD4
19 alopecia universalis congenita 10.2 CD4 AIRE
20 pernicious anemia 10.2 TG AIRE
21 thyroid gland mucoepidermoid carcinoma 10.2 TG CALCA
22 anemia, autoimmune hemolytic 10.2 CD5 CD4
23 atypical follicular adenoma 10.2 TG CALCA
24 substernal goiter 10.2 TG CALCA
25 thyroid sarcoma 10.2 TG CALCA
26 plasma protein metabolism disease 10.2 CD5 CD4
27 isthmus cancer 10.2 TG CALCA
28 fetal adenoma 10.2 TG CALCA
29 nonencapsulated sclerosing carcinoma 10.2 TG CALCA
30 acute thyroiditis 10.2 TG CALCA
31 autoimmune gastritis 10.2 CD4 AIRE
32 carotid body cancer 10.2 TG CALCA
33 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 10.2 CD4 AIRE
34 thyroid angiosarcoma 10.1 TG CALCA
35 autoimmune disease of blood 10.1 CD5 CD4
36 nasal cavity olfactory neuroblastoma 10.1 TG CALCA
37 papillary thyroid microcarcinoma 10.1 TG CALCA
38 endemic goiter 10.1 TG CALCA
39 oral hairy leukoplakia 10.1 CD4 CD1A
40 cheilitis 10.1 CD4 CD1A
41 uterus leiomyosarcoma 10.1 TG CALCA
42 nontoxic goiter 10.1 TG CALCA
43 verruciform xanthoma of skin 10.1 CD1E CD1A
44 autoimmune polyendocrine syndrome type 1 10.1 CD4 AIRE
45 graves disease 1 10.1 TG CALCA
46 chronic laryngitis 10.1 CD1E CD1A
47 multifocal motor neuropathy 10.1 CD1E CD1A
48 necrobiosis lipoidica 10.1 CD1E CD1A
49 cortical thymoma 10.1 TTN CD4 C1orf21
50 nail disease 10.1 CD4 AIRE

Graphical network of the top 20 diseases related to Dendritic Cell Thymoma:



Diseases related to Dendritic Cell Thymoma

Symptoms & Phenotypes for Dendritic Cell Thymoma

Drugs & Therapeutics for Dendritic Cell Thymoma

Search Clinical Trials , NIH Clinical Center for Dendritic Cell Thymoma

Genetic Tests for Dendritic Cell Thymoma

Anatomical Context for Dendritic Cell Thymoma

MalaCards organs/tissues related to Dendritic Cell Thymoma:

40
Lymph Node

Publications for Dendritic Cell Thymoma

Articles related to Dendritic Cell Thymoma:

(show all 15)
# Title Authors PMID Year
1
Expression of molecules of the Wnt pathway and of E-cadherin in the etiopathogenesis of human thymomas. 61
32194741 2020
2
Distinct clinical characteristics of paraneoplastic optic neuropathy. 61
30021813 2019
3
[Thymoma in a patient with klinefelter syndrome. Case report]. 61
31344216 2019
4
Drop Metastasis of Type B Thymoma 5 Years After Resection. 61
30602412 2018
5
PD-L1 immuno-expression assay in thymomas: Study of 84 cases and review of literature. 61
29661720 2018
6
Multimodality treatment of stage II thymic tumours. 61
28932541 2017
7
Expression of cathepsins V and S in thymic epithelial tumors. 61
27771373 2017
8
Thymoma masquerading as transfusion dependent anemia. 61
28144099 2016
9
Fine-needle aspiration biopsy for the diagnosis of metastatic type B thymoma to lymph nodes: a case report. 61
23456993 2014
10
Expression of c-Jun, p73, Casp9, and N-ras in thymic epithelial tumors: relationship with the current WHO classification systems. 61
22974165 2012
11
Diagnosis and subclassification of thymoma by minimally invasive fine needle aspiration directed by endobronchial ultrasound: a review and discussion of four cases. 61
22805512 2012
12
Proteome analysis and tissue array for profiling protein markers associated with type B thymoma subclassification. 61
22932072 2012
13
Expression of proteasome subunit β5t in thymic epithelial tumors. 61
21836487 2011
14
Type B thymoma: is prognosis predicted only by World Health Organization classification? 61
20038470 2010
15
Diagnostic utility of thymic epithelial markers CD205 (DEC205) and Foxn1 in thymic epithelial neoplasms. 61
17592270 2007

Variations for Dendritic Cell Thymoma

Expression for Dendritic Cell Thymoma

Search GEO for disease gene expression data for Dendritic Cell Thymoma.

Pathways for Dendritic Cell Thymoma

Pathways related to Dendritic Cell Thymoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.54 CD1E CD1B CD1A
2 11.14 CD1E CD1B CD1A
3 11.02 CD5 CD4 CD1E CD1B CD1A
4 10.84 CD4 AIRE

GO Terms for Dendritic Cell Thymoma

Cellular components related to Dendritic Cell Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.02 CD5 CD4 CD1E CD1B CD1A

Biological processes related to Dendritic Cell Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.65 CD4 CD1E CD1B CD1A AIRE
2 adaptive immune response GO:0002250 9.62 CD4 CD1E CD1B CD1A
3 positive regulation of T cell mediated cytotoxicity GO:0001916 9.33 CD1E CD1B CD1A
4 antigen processing and presentation, exogenous lipid antigen via MHC class Ib GO:0048007 9.13 CD1E CD1B CD1A
5 antigen processing and presentation, endogenous lipid antigen via MHC class Ib GO:0048006 8.8 CD1E CD1B CD1A

Molecular functions related to Dendritic Cell Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipopeptide binding GO:0071723 9.33 CD1E CD1B CD1A
2 exogenous lipid antigen binding GO:0030884 9.13 CD1E CD1B CD1A
3 endogenous lipid antigen binding GO:0030883 8.8 CD1E CD1B CD1A

Sources for Dendritic Cell Thymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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