Dendritic Cell Thymoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Dendritic Cell Thymoma

MalaCards integrated aliases for Dendritic Cell Thymoma:

Name: Dendritic Cell Thymoma ¹² ¹⁵

Epithelioid Thymoma ¹²

Type B Thymoma ⁷¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Blood diseases Immune diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:3282

NCIt ⁴⁹ C7114

UMLS ⁷¹ C1328042

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Summaries for Dendritic Cell Thymoma

MalaCards based summary : Dendritic Cell Thymoma, also known as epithelioid thymoma, is related to thymus clear cell carcinoma and thyrotoxic exophthalmos. An important gene associated with Dendritic Cell Thymoma is CD5 (CD5 Molecule), and among its related pathways/superpathways are Tight junction and Amoebiasis. Affiliated tissues include lymph node.

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Related Diseases for Dendritic Cell Thymoma

Diseases related to Dendritic Cell Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 115)

#	Related Disease	Score	Top Affiliating Genes
1	thymus clear cell carcinoma	10.4	TTN CD5
2	thyrotoxic exophthalmos	10.4	TG CD5
3	papillary thymic adenocarcinoma	10.4	TG CD5
4	endocrine exophthalmos	10.4	TG CD5
5	parapsoriasis	10.3	CD5 CD4
6	eye lymphoma	10.3	CD5 CD4
7	wissler-fanconi syndrome	10.3	CD4 AIRE
8	cardiomyopathy, familial hypertrophic, 9	10.3	TTN CD4
9	angular cheilitis	10.3	CD4 AIRE
10	autoimmune peripheral neuropathy	10.3	CD4 AIRE
11	esophageal candidiasis	10.3	CD4 AIRE
12	alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity	10.2	TG AIRE
13	subacute lymphocytic thyroiditis	10.2	TG CD4
14	granulomatous orchitis	10.2	CD1E AIRE
15	t-cell adult acute lymphocytic leukemia	10.2	CD5 CD4
16	good syndrome	10.2	CD4 AIRE
17	adrenal cortical hypofunction	10.2	TG AIRE
18	central nervous system hematologic cancer	10.2	CD5 CD4
19	alopecia universalis congenita	10.2	CD4 AIRE
20	pernicious anemia	10.2	TG AIRE
21	thyroid gland mucoepidermoid carcinoma	10.2	TG CALCA
22	anemia, autoimmune hemolytic	10.2	CD5 CD4
23	atypical follicular adenoma	10.2	TG CALCA
24	substernal goiter	10.2	TG CALCA
25	thyroid sarcoma	10.2	TG CALCA
26	plasma protein metabolism disease	10.2	CD5 CD4
27	isthmus cancer	10.2	TG CALCA
28	fetal adenoma	10.2	TG CALCA
29	nonencapsulated sclerosing carcinoma	10.2	TG CALCA
30	acute thyroiditis	10.2	TG CALCA
31	autoimmune gastritis	10.2	CD4 AIRE
32	carotid body cancer	10.2	TG CALCA
33	immunodysregulation, polyendocrinopathy, and enteropathy, x-linked	10.2	CD4 AIRE
34	thyroid angiosarcoma	10.1	TG CALCA
35	autoimmune disease of blood	10.1	CD5 CD4
36	nasal cavity olfactory neuroblastoma	10.1	TG CALCA
37	papillary thyroid microcarcinoma	10.1	TG CALCA
38	endemic goiter	10.1	TG CALCA
39	oral hairy leukoplakia	10.1	CD4 CD1A
40	cheilitis	10.1	CD4 CD1A
41	uterus leiomyosarcoma	10.1	TG CALCA
42	nontoxic goiter	10.1	TG CALCA
43	verruciform xanthoma of skin	10.1	CD1E CD1A
44	autoimmune polyendocrine syndrome type 1	10.1	CD4 AIRE
45	graves disease 1	10.1	TG CALCA
46	chronic laryngitis	10.1	CD1E CD1A
47	multifocal motor neuropathy	10.1	CD1E CD1A
48	necrobiosis lipoidica	10.1	CD1E CD1A
49	cortical thymoma	10.1	TTN CD4 C1orf21
50	nail disease	10.1	CD4 AIRE

Graphical network of the top 20 diseases related to Dendritic Cell Thymoma:

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Symptoms & Phenotypes for Dendritic Cell Thymoma

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Drugs & Therapeutics for Dendritic Cell Thymoma

Search Clinical Trials , NIH Clinical Center for Dendritic Cell Thymoma

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Genetic Tests for Dendritic Cell Thymoma

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Anatomical Context for Dendritic Cell Thymoma

MalaCards organs/tissues related to Dendritic Cell Thymoma:

⁴⁰

Lymph Node

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Publications for Dendritic Cell Thymoma

Articles related to Dendritic Cell Thymoma:

(show all 15)

#	Title	Authors	PMID	Year
1	Expression of molecules of the Wnt pathway and of E-cadherin in the etiopathogenesis of human thymomas. ⁶¹	Vodicka P...Zamecnik J	32194741	2020
2	Distinct clinical characteristics of paraneoplastic optic neuropathy. ⁶¹	Xu Q...Wei S	30021813	2019
3	[Thymoma in a patient with klinefelter syndrome. Case report]. ⁶¹	Carriel-Mancilla J...Calvo-Manuel E	31344216	2019
4	Drop Metastasis of Type B Thymoma 5 Years After Resection. ⁶¹	Heldwein MB...Hekmat K	30602412	2018
5	PD-L1 immuno-expression assay in thymomas: Study of 84 cases and review of literature. ⁶¹	Guleria P...Jain D	29661720	2018
6	Multimodality treatment of stage II thymic tumours. ⁶¹	Carillo C...Anile M	28932541	2017
7	Expression of cathepsins V and S in thymic epithelial tumors. ⁶¹	Kiuchi S...Kasahara M	27771373	2017
8	Thymoma masquerading as transfusion dependent anemia. ⁶¹	Muzamil J...Nabi F	28144099	2016
9	Fine-needle aspiration biopsy for the diagnosis of metastatic type B thymoma to lymph nodes: a case report. ⁶¹	Pusztaszeri M...Pache JC	23456993	2014
10	Expression of c-Jun, p73, Casp9, and N-ras in thymic epithelial tumors: relationship with the current WHO classification systems. ⁶¹	Ma Y...Wang J	22974165	2012
11	Diagnosis and subclassification of thymoma by minimally invasive fine needle aspiration directed by endobronchial ultrasound: a review and discussion of four cases. ⁶¹	Moonim MT...Santis G	22805512	2012
12	Proteome analysis and tissue array for profiling protein markers associated with type B thymoma subclassification. ⁶¹	Sun QL...Sha HF	22932072	2012
13	Expression of proteasome subunit β5t in thymic epithelial tumors. ⁶¹	Yamada Y...Kasahara M	21836487	2011
14	Type B thymoma: is prognosis predicted only by World Health Organization classification? ⁶¹	Kim HK...Kim K	20038470	2010
15	Diagnostic utility of thymic epithelial markers CD205 (DEC205) and Foxn1 in thymic epithelial neoplasms. ⁶¹	Nonaka D...Yee H	17592270	2007

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Genes for Dendritic Cell Thymoma

Genes related to Dendritic Cell Thymoma (0 elite genes):

(show all 12)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CD5	CD5 Molecule	Protein Coding	6.41	DISEASES inferred ¹⁵
2	TTN	Titin	Protein Coding	5.88	DISEASES inferred ¹⁵
3	TSR1	TSR1 Ribosome Maturation Factor	Protein Coding	5.78	DISEASES inferred ¹⁵
4	AIRE	Autoimmune Regulator	Protein Coding	5.58	DISEASES inferred ¹⁵
5	TG	Thyroglobulin	Protein Coding	5.25	DISEASES inferred ¹⁵
6	CD4	CD4 Molecule	Protein Coding	5.24	DISEASES inferred ¹⁵
7	C1orf21	Chromosome 1 Open Reading Frame 21	Protein Coding	5.2	DISEASES inferred ¹⁵
8	CD1E	CD1e Molecule	Protein Coding	5.16	DISEASES inferred ¹⁵
9	CD1A	CD1a Molecule	Protein Coding	5.12	DISEASES inferred ¹⁵
10	CD1B	CD1b Molecule	Protein Coding	5.11	DISEASES inferred ¹⁵
11	CHRNA1	Cholinergic Receptor Nicotinic Alpha 1 Subunit	Protein Coding	5.07	DISEASES inferred ¹⁵
12	CALCA	Calcitonin Related Polypeptide Alpha	Protein Coding	5.06	DISEASES inferred ¹⁵

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Variations for Dendritic Cell Thymoma

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Expression for Dendritic Cell Thymoma

Search GEO for disease gene expression data for Dendritic Cell Thymoma.

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Pathways for Dendritic Cell Thymoma

Pathways related to Dendritic Cell Thymoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Tight junction ³⁶	11.54	CD1E CD1B CD1A
2	Amoebiasis ³⁶	11.14	CD1E CD1B CD1A
3	Hematopoietic cell lineage ³⁶	11.02	CD5 CD4 CD1E CD1B CD1A
4	Primary immunodeficiency ³⁶	10.84	CD4 AIRE

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GO Terms for Dendritic Cell Thymoma

Cellular components related to Dendritic Cell Thymoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	external side of plasma membrane	GO:0009897	9.02	CD5 CD4 CD1E CD1B CD1A

Biological processes related to Dendritic Cell Thymoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	immune response	GO:0006955	9.65	CD4 CD1E CD1B CD1A AIRE
2	adaptive immune response	GO:0002250	9.62	CD4 CD1E CD1B CD1A
3	positive regulation of T cell mediated cytotoxicity	GO:0001916	9.33	CD1E CD1B CD1A
4	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	GO:0048007	9.13	CD1E CD1B CD1A
5	antigen processing and presentation, endogenous lipid antigen via MHC class Ib	GO:0048006	8.8	CD1E CD1B CD1A

Molecular functions related to Dendritic Cell Thymoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	lipopeptide binding	GO:0071723	9.33	CD1E CD1B CD1A
2	exogenous lipid antigen binding	GO:0030884	9.13	CD1E CD1B CD1A
3	endogenous lipid antigen binding	GO:0030883	8.8	CD1E CD1B CD1A

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