MCID: DNT046
MIFTS: 33

Dental Abscess

Categories: Oral diseases
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Aliases & Classifications for Dental Abscess

MalaCards integrated aliases for Dental Abscess:

Name: Dental Abscess 11 14 71 75

Classifications:



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Disease Ontology 11 DOID:0060324
ICD10 31 K04.6
UMLS 71 C0518988

Summaries for Dental Abscess

Disease Ontology: 11 A tooth disease characterized by a localized collection of pus associated with a tooth.

MalaCards based summary: Dental Abscess is related to hypophosphatemic rickets, x-linked recessive and hypophosphatemia. An important gene associated with Dental Abscess is PHEX (Phosphate Regulating Endopeptidase X-Linked), and among its related pathways/superpathways are Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) and Signaling by FGFR2. Affiliated tissues include salivary gland, myeloid and placenta, and related phenotypes are Synthetic lethal with c-Myc after tamoxifen stimulation and homeostasis/metabolism

Wikipedia: 75 A dental abscess is a localized collection of pus associated with a tooth. The most common type of... more...

Related Diseases for Dental Abscess

Diseases related to Dental Abscess via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 162)
# Related Disease Score Top Affiliating Genes
1 hypophosphatemic rickets, x-linked recessive 27.5 SLC34A3 SLC34A1 PHEX MEPE FGF23 FAM20C
2 hypophosphatemia 27.2 SLC34A3 SLC34A1 PTH PHEX MEPE KL
3 rickets 27.1 SLC34A3 SLC34A1 PTH PHEX MEPE KL
4 hypophosphatemic rickets, x-linked dominant 26.7 SLC34A3 SLC34A1 PTH PHEX MEPE KL
5 suppurative periapical periodontitis 11.4
6 osteogenesis imperfecta, type vi 10.2 PHEX MEPE
7 microcephaly and chorioretinopathy 1 10.2 FGF23 FAM20C
8 calciphylaxis 10.2 PTH FGF23
9 osteitis fibrosa 10.2 PTH FGF23
10 axial osteomalacia 10.2 PTH CLCN7
11 hypophosphatasia, adult 10.2 PTH ENPP1
12 blount's disease 10.2 SLC34A3 FGF23 EMP1
13 dental caries 10.1
14 cellulitis 10.1
15 pleural empyema 10.1
16 ossifying fibroma 10.1 PTH MEPE FGF23
17 osteoblastoma 10.1 PTH MEPE FGF23
18 ankylosing spondylitis 1 10.1 FGF23 CRP
19 serous labyrinthitis 10.1 SLC34A3 MEPE FAM20C
20 ureterolithiasis 10.1 PTH CRP
21 endobronchial lipoma 10.1 EMP1 CRP
22 dental pulp necrosis 10.1 MEPE DMP1
23 tumoral calcinosis, normophosphatemic, familial 10.1 GALNT3 ENPP1
24 raine syndrome 10.1 FAM20C DMP1
25 bacteremia 2 10.1
26 fasciitis 10.1
27 necrotizing fasciitis 10.1
28 hyperlipoproteinemia, type v 10.1 KL FGF23
29 dental pulp calcification 10.1 KL GALNT3
30 chronic pyelonephritis 10.1 PTH CRP
31 multiple cranial nerve palsy 10.1 CRP CLCN7
32 endosteal hyperostosis, autosomal dominant 10.1 PTH PHEX CLCN7
33 bursitis 10.1 PTH CRP
34 angioid streaks 10.1 GALNT3 ENPP1
35 familial isolated hypoparathyroidism 10.1 PTH DMP1
36 graves disease 1 10.0 PTH CRP
37 bone benign neoplasm 10.0 PTH FGF23
38 spondylolisthesis 10.0 PTH CRP
39 mediastinitis 10.0
40 metaphyseal dysplasia 10.0 SLC34A3 PTH PHEX FGF23
41 nerve compression syndrome 10.0 PTH CRP
42 osteochondrosis 10.0 PTH CRP
43 hypophosphatasia 10.0 PTH PHEX FGF23 ENPP1
44 hyperostosis 10.0 KL GALNT3 FGF23
45 spondylosis 10.0 PTH CRP
46 dentin dysplasia 10.0 MEPE DMP1
47 bone resorption disease 10.0 PTH FGF23 CRP
48 diffuse idiopathic skeletal hyperostosis 9.9 PTH ENPP1 CRP
49 hypercalcemia, infantile, 1 9.9 SLC34A1 PTH
50 chondrocalcinosis 9.9 PTH ENPP1 CRP

Graphical network of the top 20 diseases related to Dental Abscess:



Diseases related to Dental Abscess

Symptoms & Phenotypes for Dental Abscess

GenomeRNAi Phenotypes related to Dental Abscess according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 no effect GR00402-S-1 10.07 CLCN7 CRP CYP27B1 DMP1 EMP1 ENPP1
2 no effect GR00402-S-2 10.07 CRP CYP27B1 DMP1 EMP1 FAM20C FGF23
3 Synthetic lethal with c-Myc after tamoxifen stimulation GR00215-A 9.26 CRP CYP27B1 DMP1 MEPE

MGI Mouse Phenotypes related to Dental Abscess:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.21 CLCN7 CRP CYP27B1 DMP1 EMP1 ENPP1
2 renal/urinary system MP:0005367 10.17 CLCN7 CYP27B1 DMP1 ENPP1 FAM20C FGF23
3 limbs/digits/tail MP:0005371 10.1 CLCN7 CYP27B1 DMP1 ENPP1 FAM20C FGF23
4 growth/size/body region MP:0005378 10.1 CLCN7 CYP27B1 DMP1 ENPP1 FAM20C FGF23
5 immune system MP:0005387 9.93 CLCN7 CRP CYP27B1 DMP1 ENPP1 FAM20C
6 craniofacial MP:0005382 9.91 CLCN7 CYP27B1 DMP1 ENPP1 FAM20C GALNT3
7 skeleton MP:0005390 9.77 CLCN7 CYP27B1 DMP1 ENPP1 FAM20C FGF23
8 hematopoietic system MP:0005397 9.32 CLCN7 CYP27B1 DMP1 FAM20C FGF23 GALNT3

Drugs & Therapeutics for Dental Abscess

Search Clinical Trials, NIH Clinical Center for Dental Abscess

Genetic Tests for Dental Abscess

Anatomical Context for Dental Abscess

Organs/tissues related to Dental Abscess:

MalaCards : Salivary Gland, Myeloid, Placenta, Breast, Brain, Prostate, Thyroid

Publications for Dental Abscess

Articles related to Dental Abscess:

(show top 50) (show all 262)
# Title Authors PMID Year
1
Burosumab and Dental Abscesses in Children With X-Linked Hypophosphatemia. 62
36398111 2022
2
Unusual presentation of distal ICA aneurysm in relation to dental abscess. 62
36081740 2022
3
Progressive fluctuating cervical lymphadenopathy and dental abscess. 62
34893451 2022
4
The first Aotearoa New Zealand case of NUDT15-variant-related thiopurine-induced myelotoxicity. 62
35772117 2022
5
Amoxicillin-clavulanate induced DRESS syndrome masquerading as red man syndrome. 62
36387629 2022
6
Clustering of Signs and Symptoms of Oral Diseases in a Colombian Population. 62
35851446 2022
7
The efficacy and safety of different doses of calcitriol combined with neutral phosphate in X-linked hypophosphatemia: a prospective study. 62
35088103 2022
8
Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma. 62
36157700 2022
9
A Life-Saving Early Diagnosis of Burkitt Lymphoma: The Role of a Dentist. 62
34560752 2022
10
Dental Emergencies and Coronavirus Disease-2019: Scoping Review of the Literature and Single Centre Experience. 62
35621544 2022
11
Management of dental emergencies amongst Australian general medical practitioners - A case-vignette study. 62
34591999 2022
12
Endocarditis in Bovine Vein Grafts in the Pulmonary Position Placed Surgically & Percutaneously. 62
35238702 2022
13
Developing a Classification System for Prioritizing Pediatric Dental Patients Needing Treatment under General Anesthesia. 62
35881058 2022
14
Unusual extension of a dental abscess through the pterygomandibular space in subcutaneous maxillofacial tissue. 62
35106169 2022
15
Patients Perceived Knowledge, Attitude, and Practice of Dental Abscess Management in Periurban District, Ghana. 62
35769666 2022
16
Necrotizing Clostridium subterminale infection with an odontogenic origin. 62
35127448 2022
17
Complicated Odontogenic Infections at 2 District Hospitals in Tonkolili District, Sierra Leone: Protocol for a Prospective Observational Cohort Study (DELAY). 62
34898462 2021
18
Cervicofacial necrotizing fasciitis after topical application of herbal medicine. 62
34858574 2021
19
Case Report: Severe Dental Abscess Complications in Rural Sierra Leone. 62
34814107 2021
20
Monitoring response to conventional treatment in children with XLH: Value of ALP and Rickets Severity Score (RSS) in a real world setting. 62
34052463 2021
21
Early Discrimination Between Tumor-Induced Rickets/Osteomalacia and X-Linked Hypophosphatemia in Chinese Children and Adolescents: A Retrospective Case-Control Study. 62
33971042 2021
22
Odontogenic Infection Complicated by Cervicofacial Necrotizing Fasciitis in a Healthy Young Female. 62
34513425 2021
23
Cavernous Sinus Thrombosis: Efficiently Recognizing and Treating a Life-Threatening Condition. 62
34567880 2021
24
Identifying volatile in vitro biomarkers for oral bacteria with proton-transfer-reaction mass spectrometry and gas chromatography-mass spectrometry. 62
34413397 2021
25
Characteristics of paediatric dental emergencies during the COVID-19 pandemic in Riyadh City, Saudi Arabia. 62
34237997 2021
26
Bactericidal activity of a substituted thiazole against multidrug-resistant Eggerthia catenaformis isolated from patients with dental abscess. 62
33524547 2021
27
[Case report of severe acute eosinophilic pneumonia induced by amoxicillin]. 62
33902969 2021
28
Burden of oral diseases and impact of protracted displacement: a cross-sectional study on Syrian refugee children in Lebanon. 62
33986480 2021
29
Orbital Cellulitis Secondary to Dental Abscess in Children. 62
33981511 2021
30
Comparison of the treatment outcomes of the conventional stainless steel crown restorations and the hall technique in the treatment of carious primary molars. 62
33851682 2021
31
Dental Abscess to Septic Shock: A Case Report and Literature Review. 62
33422573 2021
32
Management of difficult airway in a pregnant patient with severely reduced mouth opening. 62
34057966 2021
33
A Case of Dialister pneumosintes Bacteremia-Associated Neck and Mediastinal Abscess. 62
33772571 2021
34
An evaluation of sepsis in dentistry. 62
33772188 2021
35
Eggerthia catenaformis infection originating from a dental abscess causes severe intestinal complications and osteomyelitis of the jaw. 62
33928005 2021
36
Chemical Gastroenterocolitis after Dental Root Canal Therapy with Camphorated and Mentholated Chlorophenol. 62
34258084 2021
37
Idiopathic TTP in the Middle East: Epidemiology and clinical outcomes in infection associated episodes. 62
32878734 2020
38
Comparative analysis of paediatric and adult surgically drained dental infections at a university teaching hospital. 62
33011021 2020
39
Images of the month: An incidental finding of spontaneous pneumomediastinum (Hamman's syndrome) secondary to diabetic ketoacidosis during the coronavirus pandemic. 62
33199339 2020
40
Human disease caused by Streptococcus alactolyticus: a case report of native valve infective endocarditis and review of the literature. 62
33059414 2020
41
Diagnostic difficulties in a patient with multiple sclerosis who presents with cranial nerve palsies: an unusual complication of dental work. 62
33127721 2020
42
Periapical lymphoma: Review of reported cases in the literature. 62
32035143 2020
43
Streptococcus anginosus Empyema Induced by Dental Abscess: A Case Report. 62
34434415 2020
44
Dental abscess: A potential cause of death and morbidity. 62
32864666 2020
45
Native mitral valve endocarditis due to Neisseria elongata following an untreated dental abscess. 62
32656111 2020
46
Dental emergencies at sea: A study in the French maritime TeleMedical Assistance Service. 62
30646814 2020
47
Dental care pathways for adult inpatients in an acute hospital: a five-year service evaluation. 62
32385463 2020
48
Dental procedure under opioid-free balanced anaesthesia in a child with Rett syndrome who convulsed on every attempt to feed: Case report. 62
32489209 2020
49
Case report: vertebral osteomyelitis secondary to a dental abscess. 62
32050917 2020
50
Cervical necrotizing fasciitis by dental abscess treated with negative pressure wound therapy: Case report. 62
33395898 2020

Variations for Dental Abscess

Expression for Dental Abscess

Search GEO for disease gene expression data for Dental Abscess.

Pathways for Dental Abscess

GO Terms for Dental Abscess

Biological processes related to Dental Abscess according to GeneCards Suite gene sharing:

(show all 26)
# Name GO ID Score Top Affiliating Genes
1 skeletal system development GO:0001501 10.07 PTH PHEX MEPE FAM20C
2 fibroblast growth factor receptor signaling pathway GO:0008543 10.05 FGF23 GALNT3 KL
3 positive regulation of bone mineralization GO:0030501 10.01 PTH KL FAM20C
4 bone mineralization GO:0030282 10.01 PTH PHEX ENPP1 CYP27B1
5 response to lead ion GO:0010288 9.93 SLC34A1 PTH
6 negative regulation of bone mineralization GO:0030502 9.92 FGF23 ENPP1
7 response to growth hormone GO:0060416 9.92 SLC34A1 PHEX
8 response to magnesium ion GO:0032026 9.91 SLC34A1 FGF23
9 phosphate ion transport GO:0006817 9.91 SLC34A3 SLC34A1
10 cellular response to vitamin D GO:0071305 9.9 PHEX FGF23
11 response to sodium phosphate GO:1904383 9.88 PHEX FGF23
12 calcium ion homeostasis GO:0055074 9.87 CYP27B1 FGF23 KL PTH
13 dentinogenesis GO:0097187 9.86 SLC34A1 FAM20C
14 sodium-dependent phosphate transport GO:0044341 9.85 SLC34A3 SLC34A1
15 cellular response to parathyroid hormone stimulus GO:0071374 9.85 SLC34A1 PHEX FGF23
16 regulation of bone mineralization GO:0030500 9.83 FGF23 ENPP1 CYP27B1
17 vitamin D catabolic process GO:0042369 9.81 CYP27B1 FGF23
18 response to vitamin D GO:0033280 9.8 PTH PHEX KL CYP27B1
19 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway GO:0090080 9.78 FGF23 KL
20 vitamin D metabolic process GO:0042359 9.77 FGF23 CYP27B1
21 positive regulation of vitamin D 24-hydroxylase activity GO:0010980 9.76 FGF23 CYP27B1
22 phosphate ion homeostasis GO:0055062 9.76 SLC34A1 PTH FGF23 ENPP1
23 response to fibroblast growth factor GO:0071774 9.74 PTH KL
24 response to parathyroid hormone GO:0071107 9.67 PTH SLC34A1
25 cellular phosphate ion homeostasis GO:0030643 9.56 SLC34A3 SLC34A1 FGF23 ENPP1
26 biomineral tissue development GO:0031214 9.23 PHEX MEPE FAM20C ENPP1 DMP1

Molecular functions related to Dental Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:phosphate symporter activity GO:0005436 8.92 SLC34A3 SLC34A1

Sources for Dental Abscess

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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