MCID: DNT046
MIFTS: 32

Dental Abscess

Categories: Oral diseases

Aliases & Classifications for Dental Abscess

MalaCards integrated aliases for Dental Abscess:

Name: Dental Abscess 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:0060324
ICD10 32 K04.6
UMLS 70 C0518988

Summaries for Dental Abscess

Disease Ontology : 12 A tooth disease characterized by a localized collection of pus associated with a tooth.

MalaCards based summary : Dental Abscess is related to suppurative periapical periodontitis and bone resorption disease. An important gene associated with Dental Abscess is PHEX (Phosphate Regulating Endopeptidase Homolog X-Linked), and among its related pathways/superpathways are Signaling by FGFR2 and Parathyroid hormone synthesis, secretion and action. Affiliated tissues include breast, thyroid and salivary gland, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 73 A dental abscess is a localized collection of pus associated with a tooth. The most common type of... more...

Related Diseases for Dental Abscess

Diseases related to Dental Abscess via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 139)
# Related Disease Score Top Affiliating Genes
1 suppurative periapical periodontitis 29.7 PHEX DSPP CRP
2 bone resorption disease 29.5 PTH FGF23 CRP
3 hypophosphatemic rickets, x-linked recessive 28.6 SLC34A3 PHEX MEPE FGF23 ENPP1 DSPP
4 rickets 28.3 SLC34A3 PTH PHEX MEPE KL FGF23
5 opsismodysplasia 10.3 PHEX FGF23
6 fanconi renotubular syndrome 2 10.3 SLC34A3 PHEX
7 osteogenesis imperfecta, type vi 10.2 PHEX MEPE
8 vitamin d-dependent rickets 10.2 PTH PHEX
9 calciphylaxis 10.2 PTH FGF23
10 osteitis fibrosa 10.2 PTH FGF23
11 hepatocellular clear cell carcinoma 10.2 KL FGF23
12 osteoblastoma 10.2 MEPE FGF23 EMP1
13 gorham's disease 10.2 PTH GALNT3
14 blount's disease 10.1 SLC34A3 FGF23 EMP1
15 nephrolithiasis 10.1 SLC34A3 PTH FGF23
16 ankylosing spondylitis 1 10.1 FGF23 CRP
17 endosteal hyperostosis, autosomal dominant 10.1 PTH PHEX CLCN7
18 cellulitis 10.1
19 fasciitis 10.1
20 necrotizing fasciitis 10.1
21 hyperlipoproteinemia, type v 10.1 KL FGF23
22 hypophosphatasia, adult 10.1 PTH ENPP1
23 tracheal calcification 10.1 PTH KL FGF23
24 parathyroid gland disease 10.1 PTH KL FGF23
25 primary hyperparathyroidism 10.0 PTH KL FGF23
26 ureterolithiasis 10.0 PTH CRP
27 pleural empyema 10.0
28 mediastinitis 10.0
29 bartter disease 10.0 SLC34A3 PTH CLCN7
30 hyperostosis 10.0 KL GALNT3 FGF23
31 craniometaphyseal dysplasia, autosomal dominant 10.0 PHEX ENPP1 CLCN7
32 oncogenic osteomalacia 10.0 PTH PHEX MEPE FGF23
33 parametritis 10.0 PTH CRP
34 hypophosphatasia, childhood 10.0 PTH ENPP1
35 skin atrophy 10.0 KL FGF23
36 spondylolisthesis 10.0 PTH CRP
37 dentin caries 10.0 MEPE DSPP
38 angioid streaks 10.0 GALNT3 ENPP1
39 secondary hyperparathyroidism 9.9 PTH PHEX KL FGF23
40 hyperparathyroidism 9.9 PTH PHEX KL FGF23
41 dental pulp necrosis 9.9 MEPE DSPP
42 lymphoma 9.9
43 endocarditis 9.9
44 facial paralysis 9.9
45 toxic shock syndrome 9.9
46 pericarditis 9.9
47 dental caries 9.9
48 actinomycosis 9.9
49 suppurative thyroiditis 9.9 PTH EMP1 CRP
50 pulmonary alveolar microlithiasis 9.9 SLC34A3 MEPE GALNT3 FGF23

Graphical network of the top 20 diseases related to Dental Abscess:



Diseases related to Dental Abscess

Symptoms & Phenotypes for Dental Abscess

MGI Mouse Phenotypes related to Dental Abscess:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.06 CLCN7 CRP DLX3 EMP1 ENPP1 FGF23
2 cardiovascular system MP:0005385 10.01 CRP DLX3 ENPP1 FGF23 GALNT3 KL
3 immune system MP:0005387 9.96 CLCN7 CRP ENPP1 FGF23 GALNT3 KL
4 craniofacial MP:0005382 9.91 CLCN7 DLX3 ENPP1 GALNT3 KL PHEX
5 limbs/digits/tail MP:0005371 9.7 CLCN7 ENPP1 FGF23 GALNT3 KL PHEX
6 renal/urinary system MP:0005367 9.5 CLCN7 ENPP1 FGF23 GALNT3 KL PHEX
7 skeleton MP:0005390 9.32 CLCN7 ENPP1 FGF23 GALNT3 KL MEPE

Drugs & Therapeutics for Dental Abscess

Search Clinical Trials , NIH Clinical Center for Dental Abscess

Genetic Tests for Dental Abscess

Anatomical Context for Dental Abscess

MalaCards organs/tissues related to Dental Abscess:

40
Breast, Thyroid, Salivary Gland, Skin, Placenta, Prostate

Publications for Dental Abscess

Articles related to Dental Abscess:

(show top 50) (show all 229)
# Title Authors PMID Year
1
Dental Abscess to Septic Shock: A Case Report and Literature Review. 61
33422573 2021
2
An evaluation of sepsis in dentistry. 61
33772188 2021
3
A Case of Dialister pneumosintes Bacteremia-Associated Neck and Mediastinal Abscess. 61
33772571 2021
4
Bactericidal activity of a substituted thiazole against multidrug-resistant Eggerthia catenaformis isolated from patients with dental abscess. 61
33524547 2021
5
Comparative analysis of paediatric and adult surgically drained dental infections at a university teaching hospital. 61
33011021 2020
6
Idiopathic TTP in the Middle East: Epidemiology and clinical outcomes in infection associated episodes. 61
32878734 2020
7
Images of the month: An incidental finding of spontaneous pneumomediastinum (Hamman's syndrome) secondary to diabetic ketoacidosis during the coronavirus pandemic. 61
33199339 2020
8
Human disease caused by <em>Streptococcus alactolyticus</em>: a case report of native valve infective endocarditis and review of the literature. 61
33059414 2020
9
Diagnostic difficulties in a patient with multiple sclerosis who presents with cranial nerve palsies: an unusual complication of dental work. 61
33127721 2020
10
Periapical lymphoma: Review of reported cases in the literature. 61
32035143 2020
11
Dental abscess: A potential cause of death and morbidity. 61
32864666 2020
12
Dental emergencies at sea: A study in the French maritime TeleMedical Assistance Service. 61
30646814 2020
13
Native mitral valve endocarditis due to Neisseria elongata following an untreated dental abscess. 61
32656111 2020
14
Dental care pathways for adult inpatients in an acute hospital: a five-year service evaluation. 61
32385463 2020
15
Dental procedure under opioid-free balanced anaesthesia in a child with Rett syndrome who convulsed on every attempt to feed: Case report. 61
32489209 2020
16
Case report: vertebral osteomyelitis secondary to a dental abscess. 61
32050917 2020
17
Deep neck space infection and Lemierre's syndrome caused by Streptococcus anginosus: A case report. 61
32226760 2020
18
Cervical necrotizing fasciitis by dental abscess treated with negative pressure wound therapy: Case report. 61
33395898 2020
19
Hepatic abscess due to Dialister pneumosintes - A case report. 61
31103532 2019
20
The role of poor oral health in surgical site infection following elective spinal surgery. 61
30269297 2019
21
Preformed pediatric zirconia crown versus preformed pediatric metal crown: study protocol for a randomized clinical trial. 61
31445509 2019
22
Preseptal and Postseptal Orbital Cellulitis of Odontogenic Origin. 61
31516796 2019
23
Dental assessment prior to orthopedic surgery: A systematic review. 61
31060914 2019
24
Pediatric preseptal and orbital cellulitis: A 10-year experience. 61
30772617 2019
25
A Rare Case of Odontogenic Chronic Suppurative Otitis Media. 61
31172000 2019
26
Streptococcus gordonii: A Rare Cause of Infective Endocarditis. 61
31281690 2019
27
Histopathologic and immunohistochemical investigations of dental abscess formed in maxillofacial area. 61
31063202 2019
28
Spontaneous cerebral abscess due to Bacillus subtilis in an immunocompetent male patient: A case report and review of literature. 61
30613677 2018
29
Dental Problems in Primary Care. 61
30485039 2018
30
Persistent Buccal Swelling: Diagnostic Dilemma. 61
30906682 2018
31
Mixed connective tissue disease in young Saudi patient with recurrent dental abscess: A case report. 61
30534045 2018
32
Dental Abscess in Pediatric Patients: A Marker of Neglect. 61
30211838 2018
33
Deep neck infection and descending mediastinitis as lethal complications of dentoalveolar infection: two rare case reports. 61
29980234 2018
34
Fatal Ludwig's Angina: Cases of Lethal Spread of Odontogenic Infection. 61
31240032 2018
35
Case Report: Sporadic Burkitt lymphoma misdiagnosed as dental abscess in a 15-year-old girl. 61
32117562 2018
36
Oral surgery II: Part 2. The maxillary sinus (antrum) and oral surgery. 61
29026224 2017
37
Diagnoses and Treatment of Dental Disorders in a Research Colony of Macaca fascicularis: A Case Series. 61
28814183 2017
38
Pediatric Sepsis Secondary to an Occult Dental Abscess: A Case Report. 61
28262381 2017
39
Neanderthal behaviour, diet, and disease inferred from ancient DNA in dental calculus. 61
28273061 2017
40
Facial Palsy Masquerading as an Acute Dental Abscess. 61
29172335 2017
41
Role of Thr399Ile and Asp299Gly polymorphisms of toll-like receptor-4 gene in acute dental abscess. 61
28210435 2017
42
Odontogenic Orofacial Infections. 61
27930461 2017
43
Aggressive Adenoid Cystic Carcinoma of Maxillary Sinus in a 43-Year-Old Male: Rare Case Report and Review of Literature. 61
29093739 2017
44
Magnetic Resonance Imaging Features as Surrogate Markers of X-Linked Hypophosphatemic Rickets Activity. 61
28376474 2017
45
Management of Amelogenesis Imperfecta: A 15-Year Case History of Two Siblings. 61
27589272 2016
46
Successful treatment of periprosthetic joint infection caused by Granulicatella para-adiacens with prosthesis retention: a case report. 61
27067804 2016
47
Orbital Infection Threatening Blindness Due to Carious Primary Molars: An Interesting Case Report. 61
26929556 2016
48
Hypophosphatemic Rickets and Pre-eruptive Spontaneous Dental Abscess. 61
27098722 2016
49
Mandibular Destruction Secondary to Invasion by Carcinoma Cuniculatum. 61
26072180 2015
50
Oral health in prehistoric San Pedro de Atacama oases, Northern Chile. 61
26253130 2015

Variations for Dental Abscess

Expression for Dental Abscess

Search GEO for disease gene expression data for Dental Abscess.

Pathways for Dental Abscess

Pathways related to Dental Abscess according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.62 KL GALNT3 FGF23
2 10.95 SLC34A3 PTH KL FGF23
3 10.1 PTH FGF23

GO Terms for Dental Abscess

Cellular components related to Dental Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.17 PTH MEPE KL FGF23 ENPP1 DSPP

Biological processes related to Dental Abscess according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 fibroblast growth factor receptor signaling pathway GO:0008543 9.61 KL GALNT3 FGF23
2 positive regulation of bone mineralization GO:0030501 9.56 PTH KL
3 calcium ion homeostasis GO:0055074 9.55 PTH KL
4 regulation of bone mineralization GO:0030500 9.54 FGF23 ENPP1
5 phosphate-containing compound metabolic process GO:0006796 9.52 FGF23 ENPP1
6 response to vitamin D GO:0033280 9.51 PTH PHEX
7 negative regulation of bone mineralization GO:0030502 9.49 FGF23 ENPP1
8 cellular response to vitamin D GO:0071305 9.48 PHEX FGF23
9 cellular response to parathyroid hormone stimulus GO:0071374 9.46 PHEX FGF23
10 skeletal system development GO:0001501 9.46 PTH PHEX MEPE DSPP
11 phosphate ion homeostasis GO:0055062 9.4 PTH FGF23
12 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway GO:0090080 9.37 KL FGF23
13 response to sodium phosphate GO:1904383 9.32 PHEX FGF23
14 odontoblast differentiation GO:0071895 9.26 DSPP DLX3
15 cellular phosphate ion homeostasis GO:0030643 9.13 SLC34A3 FGF23 ENPP1
16 biomineral tissue development GO:0031214 8.92 PHEX MEPE ENPP1 DSPP

Molecular functions related to Dental Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 fibroblast growth factor receptor binding GO:0005104 8.62 KL FGF23

Sources for Dental Abscess

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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