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MCID: DNT046
MIFTS: 29

Dental Abscess

Categories: Oral diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Dental Abscess

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MalaCards integrated aliases for Dental Abscess:

Name: Dental Abscess 12 15 73

Classifications:

MalaCards categories:
Anatomical: Oral diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:0060324
ICD10 33 K04.6
UMLS 73 C0518988
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Summaries for Dental Abscess

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Disease Ontology : 12 A tooth disease characterized by a localized collection of pus associated with a tooth.

MalaCards based summary : Dental Abscess is related to osteopetrosis, autosomal dominant 2 and osteopetrosis, autosomal dominant 1. An important gene associated with Dental Abscess is PHEX (Phosphate Regulating Endopeptidase Homolog X-Linked), and among its related pathways/superpathways is Neuroscience. The drugs Anti-Bacterial Agents and Antibiotics, Antitubercular have been mentioned in the context of this disorder. Affiliated tissues include lung, and related phenotype is renal/urinary system.

Wikipedia : 76 A dental abscess (also termed a dentoalveolar abscess, tooth abscess or root abscess), is a localized... more...

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Related Diseases for Dental Abscess

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Diseases related to Dental Abscess via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 79)
# Related Disease Score Top Affiliating Genes
1 osteopetrosis, autosomal dominant 2 11.1
2 osteopetrosis, autosomal dominant 1 10.9
3 intracranial abscess 10.6 BIN1 CRP
4 peptic ulcer perforation 10.5 AMELX CRP
5 tooth resorption 10.5 ACP5 AMELX
6 tendinitis 10.4 ACP5 CRP
7 skeletal tuberculosis 10.4 AMELX CRP
8 bronchus cancer 10.4 AVP CRP
9 japanese spotted fever 10.4 CRP KANTR
10 subdural empyema 10.3 CRP KANTR
11 peripheral vertigo 10.3 AVP CRP
12 teeth hard tissue disease 10.3 ACP5 AMELX
13 analbuminemia 10.3 AVP CRP
14 calcific tendinitis 10.3 CRP KANTR
15 granulomatous hepatitis 10.3 AVP CRP
16 suppurative otitis media 10.2 CRP TLR4
17 hypertropia 10.2 ACP5 KANTR
18 pyelitis 10.2 CRP TLR4
19 oculomotor nerve paralysis 10.2 AVP KANTR
20 third cranial nerve disease 10.2 AVP KANTR
21 sphenoid sinusitis 10.2 AVP KANTR
22 septic arthritis 10.2 CRP TLR4
23 scrub typhus 10.2 CRP TLR4
24 pancreas disease 10.2 AVP CRP
25 bone remodeling disease 10.2 ACP5 PHEX
26 perinatal necrotizing enterocolitis 10.1 CRP TLR4
27 premenstrual tension 10.1 AVP KANTR
28 bone fracture 10.1 CRP TLR4
29 trench fever 10.1 KANTR TLR4
30 pelvic inflammatory disease 10.1 CRP TLR4
31 carotid artery dissection 10.1 AVP KANTR
32 uterine anomalies 10.1 CRP TLR4
33 brucellosis 10.0 CRP TLR4
34 testicular infarct 10.0 CRP KIT
35 pyelonephritis 10.0 CRP TLR4
36 pyosalpinx 10.0 CRP KIT
37 typhoid fever 10.0 CRP TLR4
38 neurogenic bowel 10.0 CA2 KIT
39 coronary stenosis 9.9 CRP TLR4
40 mixed type thymoma 9.9 AVP KIT
41 chorioamnionitis 9.8 CRP TLR4
42 functional colonic disease 9.8 KANTR KIT
43 primary bacterial infectious disease 9.8 CRP TLR4
44 colonic pseudo-obstruction 9.7 KANTR KIT
45 leukocyte disease 9.7 CRP KIT
46 rickets 9.7
47 autoinflammation, lipodystrophy, and dermatosis syndrome 9.6 CRP TLR4
48 porphyria, acute intermittent 9.6
49 lymphoma, hodgkin, classic 9.6
50 rheumatic fever-related antigen 9.6

Graphical network of the top 20 diseases related to Dental Abscess:



Diseases related to Dental Abscess
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Symptoms & Phenotypes for Dental Abscess

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MGI Mouse Phenotypes related to Dental Abscess:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 9.02 AVP CA2 KIT PHEX TLR4
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Drugs & Therapeutics for Dental Abscess

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Drugs for Dental Abscess (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anti-Bacterial Agents Phase 4
2 Antibiotics, Antitubercular Phase 4
3 Calcium, Dietary Phase 4
4
Menthol Approved Not Applicable 2216-51-5 16666
5 sodium fluoride Approved Not Applicable 7681-49-4
6 Anesthetics Not Applicable
7 Fluorides Not Applicable
8 Listerine Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparison of Two Dental Techniques Used to Treat Teeth Which Have Become Infected or Painful Following Trauma Completed NCT01817413 Phase 4
2 A Long-Term Extension Study of RoActemra/Actemra (Tocilizumab) in Patients With Juvenile Idiopathic Arthritis From France Who Completed WA19977 Core Study Completed NCT01673919 Phase 3 tocilizumab [RoActemra/Actemra]
3 European Study on Three Different Approaches to Managing Class 2 Cavities in Primary Teeth Completed NCT01797458 Not Applicable

Search NIH Clinical Center for Dental Abscess

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Genetic Tests for Dental Abscess

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Anatomical Context for Dental Abscess

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MalaCards organs/tissues related to Dental Abscess:

41
Lung
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Publications for Dental Abscess

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Articles related to Dental Abscess:

(show all 33)
# Title Authors Year
1
Pediatric Sepsis Secondary to an Occult Dental Abscess: AA Case Report. ( 28262381 )
2017
2
Facial Palsy Masquerading as an Acute Dental Abscess. ( 29172335 )
2017
3
Role of Thr399Ile and Asp299Gly polymorphisms of toll-like receptor-4 gene in acute dental abscess. ( 28210435 )
2017
4
Hypophosphatemic Rickets and Pre-eruptive Spontaneous Dental Abscess. ( 27098722 )
2016
5
First clinical description of Eggerthia catenaformis bacteremia in a patient with dental abscess. ( 26172397 )
2015
6
A dental myth bites the dust--no observable relation between the incidence of dental abscess and the weather and lunar phase: an ecological study. ( 25888138 )
2015
7
Oral maxillofacial: dangerous dental abscess. ( 26076550 )
2015
8
Ewing's sarcoma in mandibular similar to dental abscess. ( 24627870 )
2014
9
Malignant fibrous histiocytoma clinically mimicking dental abscess in a child: report of an unusual case. ( 24941550 )
2014
10
Epidemiology and variables involved in dental abscess: survey of dental emergency unit in Trieste. ( 23879656 )
2014
11
Anesthesia challenge in dental abscess induced trismus: a case report. ( 25007700 )
2014
12
Actinomycosis with septic pulmonary emboli developing after dental abscess. ( 24182712 )
2013
13
Sadyo Vamana for dental abscess. ( 24501448 )
2013
14
Dental abscess: A microbiological review. ( 24348613 )
2013
15
Bilateral cavernous sinus thrombosis and facial palsy as complications of dental abscess. ( 24665189 )
2013
16
Osteosarcoma of the mandible masquerading as a dental abscess: report of a case. ( 23243522 )
2012
17
Role of Sadyo Vamana in dental abscess (danta arbuda). ( 24167336 )
2012
18
RE: histopathological documented cryptococcal lung lesion associated with diabetes mellitus and dental abscess. ( 23113433 )
2012
19
Comparison of bedside ultrasound and panorex radiography in the diagnosis of a dental abscess in the ED. ( 20825898 )
2011
20
Florid cemento-osseous dysplasia and a dental abscess. ( 22187807 )
2011
21
Maltreated dental abscess complicated with chest wall necrotizing fasciitis, empyema thorax and cardiac tamponade. ( 20185855 )
2010
22
Familial hypophosphatemic vitamin D-resistant rickets--prevention of spontaneous dental abscesses on primary teeth: a case report. ( 19201216 )
2009
23
Primary extranodal non-Hodgkin lymphoma of the gingiva initially misdiagnosed as dental abscess. ( 19898711 )
2009
24
The microbiology of the acute dental abscess. ( 19141730 )
2009
25
Superficial cervical plexus block combined with auriculotemporal nerve block for drainage of dental abscess in adults with difficult airways. ( 19157359 )
2009
26
Association of CD14, IL1B, IL6, IL10 and TNFA functional gene polymorphisms with symptomatic dental abscesses. ( 17511783 )
2007
27
A case of tularemia presenting as a dental abscess: case report. ( 17178484 )
2007
28
A previously unreported association between Nance-Horan syndrome and spontaneous dental abscesses. ( 15660094 )
2005
29
Actinomyces dentalis sp. nov., from a human dental abscess. ( 15653913 )
2005
30
Branch retinal artery occlusion: a case complicating acute rheumatic fever and dental abscess. ( 10953747 )
2000
31
Toxic shock syndrome secondary to a dental abscess. ( 10065654 )
1999
32
The management of a dental abscess in a patient with acute intermittent porphyria. A case report. ( 1387703 )
1992
33
Pansinusitis, orbital cellulitis, and blindness as sequelae of delayed treatment of dental abscess. ( 4519135 )
1974
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Variations for Dental Abscess

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Expression for Dental Abscess

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Search GEO for disease gene expression data for Dental Abscess.
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Pathways for Dental Abscess

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Pathways related to Dental Abscess according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Neuroscience 4
11.33 AVP BIN1 CA2
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GO Terms for Dental Abscess

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Biological processes related to Dental Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 odontogenesis of dentin-containing tooth GO:0042475 9.32 AMELX CA2
2 negative regulation of tumor necrosis factor production GO:0032720 9.26 ACP5 TLR4
3 positive regulation of gene expression GO:0010628 9.26 AVP CRP KIT TLR4
4 biomineral tissue development GO:0031214 9.16 AMELX PHEX
5 positive regulation of cellular pH reduction GO:0032849 8.62 AVP CA2
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Sources for Dental Abscess

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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