MCID: DNT012
MIFTS: 51

Dental Caries

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Dental Caries

MalaCards integrated aliases for Dental Caries:

Name: Dental Caries 12 76 55 44 15 73
Dental Caries Extending into Pulp 12
Dental Caries of Smooth Surface 12
Dental Caries Pit and Fissure 12

Classifications:



External Ids:

Disease Ontology 12 DOID:216
ICD10 33 K02 K02.6 K02.9
MeSH 44 D003731
NCIt 50 C52593

Summaries for Dental Caries

MalaCards based summary : Dental Caries, also known as dental caries extending into pulp, is related to root caries and dental fluorosis, and has symptoms including halitosis and snoring. An important gene associated with Dental Caries is CD79A (CD79a Molecule), and among its related pathways/superpathways is Salivary secretion. The drugs Abacavir and Dolutegravir have been mentioned in the context of this disorder. Affiliated tissues include testes, breast and lung, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 76 Tooth decay, also known as dental caries or cavities, is a breakdown of teeth due to acids made by... more...

Related Diseases for Dental Caries

Diseases related to Dental Caries via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 83)
# Related Disease Score Top Affiliating Genes
1 root caries 33.2 CD79A DSPP LTF
2 dental fluorosis 31.5 AMELX DSPP
3 aplasia of lacrimal and salivary glands 31.4 DSPP FGF10 LPO LTF
4 dentin caries 11.7
5 enamel caries 11.3
6 periapical periodontitis 11.1
7 tricho-dento-osseous syndrome 1 11.1
8 flynn-aird syndrome 11.0
9 cockayne syndrome a 11.0
10 cutis laxa, autosomal recessive, type iia 11.0
11 insensitivity to pain, congenital, with anhidrosis 11.0
12 osteopetrosis, autosomal recessive 1 11.0
13 benjamin syndrome 11.0
14 dominant dystrophic epidermolysis bullosa 11.0
15 recessive dystrophic epidermolysis bullosa-generalized other 11.0
16 odontoclasia 10.7
17 parotitis 10.6 CD79A LTF
18 amelogenesis imperfecta, hypoplastic/hypomaturation, x-linked 2 10.6 AMELX TUFT1
19 tooth erosion 10.6 DSPP TUFT1
20 acute diarrhea 10.6 CD79A LTF
21 amelogenesis imperfecta, type iiia 10.6 AMELX ENAM
22 amelogenesis imperfecta, type ie 10.5 AMELX TUFT1
23 dental pulp necrosis 10.5 AMELX DSPP
24 dental pulp calcification 10.5 DSPP ENAM
25 periodontitis 10.5
26 aging 10.4
27 hypercementosis 10.3 DSPP ENAM
28 periodontal disease 10.3
29 tooth resorption 10.3 AMELX DSPP
30 body mass index quantitative trait locus 1 10.3
31 chickenpox 10.3 CD79A LTF
32 hypocalcified amelogenesis imperfecta 10.2 DSPP ENAM TUFT1
33 gingivitis 10.2
34 diabetes mellitus 10.1
35 down syndrome 10.1
36 asthma 10.0
37 cerebral palsy 10.0
38 cerebritis 10.0
39 dysentery 10.0 CD79A LTF
40 alacrima, achalasia, and mental retardation syndrome 10.0
41 cleft lip 10.0
42 cleft lip/palate 10.0
43 teeth hard tissue disease 10.0 AMELX DSPP ENAM TUFT1
44 attention deficit-hyperactivity disorder 9.9
45 schizophrenia 9.9
46 cystic fibrosis 9.9
47 sjogren syndrome 9.9
48 anxiety 9.9
49 graft-versus-host disease 9.9
50 hemangioma 9.9

Comorbidity relations with Dental Caries via Phenotypic Disease Network (PDN): (show all 13)


Acute Apical Periodontitis Acute Cystitis
Acute Pericementitis Alzheimer Disease
Aortic Valve Disease 1 Deficiency Anemia
Familial Atrial Fibrillation Gingivitis
Heart Disease Ischemic Heart Disease
Periodontitis, Chronic Periodontosis
Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Dental Caries:



Diseases related to Dental Caries

Symptoms & Phenotypes for Dental Caries

UMLS symptoms related to Dental Caries:


halitosis, snoring

GenomeRNAi Phenotypes related to Dental Caries according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00240-S-1 10.5 DSPP
2 Decreased viability GR00381-A-1 10.5 LTF CD79A MUC7 CST1 DSPP TAS1R2
3 Decreased viability GR00381-A-3 10.5 LTF CD79A TAS1R2 TUFT1
4 Decreased viability GR00402-S-2 10.5 FGF10 HTN1 AJAP1 LPO AMELX LTF
5 no effect GR00402-S-1 9.62 HTN1 AJAP1 LPO AMELX CA6 LTF
6 Increased gamma-H2AX phosphorylation GR00053-A 9.61 HTN1 AJAP1 LTF CD79A MUC7 CST1

Drugs & Therapeutics for Dental Caries

Drugs for Dental Caries (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 574)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Abacavir Approved, Investigational Phase 4,Phase 2 136470-78-5 65140 441300
2 Dolutegravir Approved Phase 4,Phase 3 1051375-16-6 54726191
3
Efavirenz Approved, Investigational Phase 4,Phase 2,Not Applicable 154598-52-4 64139
4
Emtricitabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 143491-57-0 60877
5
Lamivudine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 134678-17-4 60825
6 sodium fluoride Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 7681-49-4
7
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 22916-47-8 4189
8
Salicylic acid Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 69-72-7 338
9
Dopamine Approved Phase 4,Phase 2,Phase 1,Not Applicable 51-61-6, 62-31-7 681
10
Methamphetamine Approved, Illicit Phase 4,Phase 2,Phase 1,Not Applicable 537-46-2 10836
11
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 55-56-1 9552079 2713
12
Sorbitol Approved Phase 4,Phase 2,Phase 3,Not Applicable 50-70-4 5780
13
Zinc Approved, Investigational Phase 4,Phase 3,Not Applicable 7440-66-6 23994
14
Zinc oxide Approved Phase 4,Not Applicable 1314-13-2
15
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
16
Midazolam Approved, Illicit Phase 4,Phase 1 59467-70-8 4192
17
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
18
Enfuvirtide Approved, Investigational Phase 4,Not Applicable 159519-65-0 16130199
19 Pinaverium Approved Phase 4 59995-65-2
20
Ethanol Approved Phase 4,Phase 1,Phase 2,Not Applicable 64-17-5 702
21
Peginterferon alfa-2a Approved, Investigational Phase 4,Phase 2 198153-51-4 5360545
22
Peginterferon alfa-2b Approved Phase 4,Phase 2 99210-65-8, 215647-85-1
23
Ribavirin Approved Phase 4,Phase 2,Not Applicable 36791-04-5 37542
24
Chloramphenicol Approved, Vet_approved Phase 4 56-75-7 298 5959
25
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
26
Rosiglitazone Approved, Investigational Phase 4 122320-73-4 77999
27
Adenosine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 58-61-7 60961
28
Regadenoson Approved, Investigational Phase 4 313348-27-5 219024
29
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 1 76-42-6 5284603
30
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
31
Indapamide Approved Phase 4 26807-65-8 3702
32
Irbesartan Approved, Investigational Phase 4 138402-11-6 3749
33
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 1,Phase 2 148553-50-8 5486971
34
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 1 16590-41-3 5360515
35
Thymol Approved Phase 4,Not Applicable 89-83-8 6989
36
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
37
Morphine Approved, Investigational Phase 4 57-27-2 5288826
38
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4 1406-16-2
39
Vitamin D3 Approved, Nutraceutical Phase 4 67-97-0 6221 5280795
40
Chloramphenicol succinate Experimental Phase 4 3544-94-3
41
2,4-thiazolidinedione Investigational Phase 4 2295-31-0
42 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
43 Fluorides Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
44 Cariostatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
45 Olaflur Phase 4,Not Applicable
46 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
47 Anti-HIV Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
48 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
49 Anti-Retroviral Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
50 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 1026)
# Name Status NCT ID Phase Drugs
1 Dental Caries Management by Risk Assessment: Identification and Treatment of Risk Factors Among (IDF) Personnel Unknown status NCT01142440 Phase 4
2 Elmex Gel Efficacy in Preventing White Spot Lesions Unknown status NCT00268138 Phase 4 elmex gel
3 Consumption Effect of Probiotic Products on Salivary Cariogenic Bacterial Counts in Preschool Children. Unknown status NCT02692625 Phase 4
4 Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2). Unknown status NCT01778699 Phase 4
5 Efavirenz to Dolutegravir Switch in Patients With CNS Toxicity Unknown status NCT02285374 Phase 4 Dolutegravir, efavirenz, efavirenz/emtricitabine/tenofovir
6 Prevention of Dental Caries Lesions With Fluoride Varnish in Erupting First Permanent Molars Completed NCT02592278 Phase 4 Fluoride Varnish;Control Group
7 Fluoride Varnish For Childsmile Nursery School Attenders Completed NCT01674933 Phase 4 Duraphat® Fluoride Varnish
8 Use of Fissure Sealants on Primary Molars Completed NCT01438866 Phase 4
9 Therapeutic Effect of Two Fluoride Varnishes on White Spot Lesions: a Clinical Study Completed NCT00723515 Phase 4 sodium fluoride;sodium fluoride calcium fluoride
10 Impact of Maternal Xylitol Consumption on Mutans Sterptococci Completed NCT02036151 Phase 4 xylitol;fluoride varnish application
11 Preventive and Therapeutic Proximal Sealants Completed NCT02338180 Phase 4
12 Impact of Fluoride Vanish Application in Dental Prevention for Elderly Completed NCT01038817 Phase 4 Duraphat
13 The Effect of Silver Diamine Fluoride (SDF) on Bacteria Involved in Root or Cervical Carious Lesions Completed NCT02953886 Phase 4
14 Effect of the Amount of Fluoride Toothpaste on Fluoride Availability in the Oral Fluids in Children Completed NCT03455621 Phase 4
15 Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment Completed NCT02447289 Phase 4 Intranasal ketamine;Oral ketamine;Intranasal midazolam;Oral midazolam
16 Fuji Type VII Sealant Versus Resin Based Sealant. A Clinical Trial Completed NCT02795728 Phase 4
17 Comparison of the Effect of Fluoride Remineralizer Gel and Foam Completed NCT02490592 Phase 4
18 Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients Completed NCT01768390 Phase 4
19 Postoperative Pulpal Complications in Posterior Resin Composite Restorations Without Glass-ionomer Cement Lining Completed NCT01567514 Phase 4
20 Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride Completed NCT01563172 Phase 4 Sodium fluoride / silica and carbopol, 0.5g;Sodium fluoride / silica and carbopol, 1.5g;Sodium fluoride / silica and carbopol, 1.5g
21 Enamel Remineralization Potential of Dentifrices in Situ Completed NCT01128946 Phase 4 NaF;SnF;NaMFP
22 MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization Study Completed NCT02424097 Phase 4 CPP-ACP 5% sodium fluoride varnish & 900ppm fluoride paste;1,100pm F-toothpaste and 0.5%NaF rinse
23 Interaction Between Chlorhexidine and Fluoride Completed NCT02935322 Phase 4 0.12 % chlorhexidine + 0.2 % NaF mouthrinse;0.2 % NaF mouthrinse;0.12% chlorhexidine
24 Bifidobacterium Lactis BB12 and Xylitol Delivered With a Novel Slow-release Pacifier Completed NCT00638677 Phase 4
25 Efficacy of Moderate Sedation for Dental Treatment of Young Children Completed NCT00902395 Phase 4 Midazolam;Midazolam, ketamine
26 Comparison of Topical Analgesic With Saline Rinses in Post Extraction Healing Completed NCT02921165 Phase 4 analgesic mouth rinses (dissolved Aspirin);Normal saline rinses.
27 A Study to Evaluate of the Efficacy of Enfuvirtide During the Induction Phase of Therapy Completed NCT00344760 Phase 4 Enfuvirtide;Efavirenz, lamivudine, and tenofovir
28 Pinverin Application Trial to Reduce Bowel Uptake of FDG (Fluorodeoxyglucose) Completed NCT02173964 Phase 4 pinaverium bromide;water
29 Effects of Two Sugar Substituted Chewing Gums on Caries and Gingivitis Variables Completed NCT01578603 Phase 4
30 Remineralisation of White Spot Lesions by Elmex® gelée in Post-orthodontic Patients Completed NCT01329731 Phase 4 elmex® gelée;negative control (placebo)
31 Different PEG-interferon and Ribavirin Schedules for Chronic Hepatitis C in the Real Clinical Practice. Completed NCT01195181 Phase 4 peginterferon plus ribavirin
32 MI Varnish for the Prevention of White Spot Lesions Completed NCT03446690 Phase 4 MI Varnish
33 Treatment of Immature Permanent Teeth With Three Different Pulp Capping Materials With Partial Pulpotomy Completed NCT03426046 Phase 4 Pulp Capping Agents
34 Antimicrobial Pulpotomy of Primary Molars Completed NCT01010451 Phase 4
35 Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study Completed NCT01601145 Phase 4
36 Music Distraction Strategy in Children Dental Care Completed NCT02489812 Phase 4
37 Effect of Rosiglitazone Versus Placebo on Cardiovascular Performance and Myocardial Triglyceride Completed NCT00424762 Phase 4 rosiglitazone;placebo
38 Oral Fluoride Bioavailability by the Consumption of Meals Prepared With Fluoridated Water or Salt Completed NCT02776280 Phase 4
39 Regadenoson Blood Flow in Type 1 Diabetes (RABIT1D) Completed NCT01019486 Phase 4 Regadenoson myocardial perfusion imaging;Regadenoson MRI myocardial blood flow
40 Safety and Immunogenicity of 1 or 2 Doses of IPV in Latin American Infants Primed With Bivalent OPV Vaccine Completed NCT01831050 Phase 4
41 Comparison of the Effects of Tapentadol and Oxycodone on Gastrointestinal and Colonic Transit in Humans Completed NCT01500317 Phase 4 Tapentadol;Oxycodone;Placebo
42 A Pharmacodynamic Study to Evaluate Neutrophil Distribution Kinetics and Function Following Single-Dose RoActemra/Actemra (Tocilizumab) in Healthy Volunteers Completed NCT01991990 Phase 4 placebo;tocilizumab [RoActemra/Actemra]
43 Renal Denervation in Diabetic Nephropathy Completed NCT01588795 Phase 4 Standardized antiproteinuric medication regimen includes an angiotensin receptor blocker , a diuretic , 25OH vitamin D3 and a statin
44 A Study Of Pregabalin (Lyrica) Drug Levels In Urine, Plasma And Breast Milk Of Healthy Lactating Women Completed NCT01727791 Phase 4 pregabalin (Lyrica)
45 Comparison of ACTIVA BioACTIVE Versus Compomer in Restoring Dental Decay in Primary Molar Teeth Recruiting NCT03516838 Phase 4 ACTIVA™ BioACTIVE;Compomer
46 Occlusal Caries Management in First Permanent Molars in Child Dental Care Recruiting NCT03315312 Phase 4 Fluoride Varnishes;Fissure Sealants
47 Treatment of Primary Molars With Deep Caries Using Silver Diamine Fluoride Recruiting NCT03563534 Phase 4 Silver Diamine Fluoride;Glass Ionomer
48 Cost-efficacy Between ART and Composite Resin Restorations in Primary Molars Recruiting NCT02562456 Phase 4
49 Duration of IPV Priming and Antibody Decay Recruiting NCT03202719 Phase 4
50 Treatment of Postorthodontic White Spot Lesions Recruiting NCT03217084 Phase 4 MI varnish GC;White varnish 3M

Search NIH Clinical Center for Dental Caries

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: dental caries

Genetic Tests for Dental Caries

Anatomical Context for Dental Caries

MalaCards organs/tissues related to Dental Caries:

41
Testes, Breast, Lung, Heart, Prostate, Bone, Salivary Gland

Publications for Dental Caries

Articles related to Dental Caries:

(show top 50) (show all 784)
# Title Authors Year
1
Redefining the Phenotype of Dental Caries. ( 29393149 )
2018
2
Inequalities in dental caries experience among 4-year-old New Zealand children. ( 29419880 )
2018
3
The Associations of School Oral Health-Related Environments with Oral Health Behaviours and Dental Caries in Children. ( 29393138 )
2018
4
Do Signs of Attention-Deficit/Hyperactivity Disorder Increase the Odds of Dental Caries? A Case-Control Study. ( 29393165 )
2018
5
Obesity and Dental Caries in Young Children in Plymouth, United Kingdom: A Spatial Analysis. ( 29380963 )
2018
6
Effect of inhaled medication on dental caries index in asthmatic children. ( 29402495 )
2018
7
Relations among obesity, family socioeconomic status, oral health behaviors, and dental caries in adolescents: the 2010-2012 Korea National Health and nutrition examination survey. ( 29929557 )
2018
8
Consortium genome-wide meta-analysis for childhood dental caries traits. ( 29931343 )
2018
9
Dental caries prevention strategies among children and adolescents with immigrantA - or low socioeconomic backgrounds- do they work? A systematic review. ( 29415706 )
2018
10
Deciduous dental caries status and associated risk factors among preschool children in Xuhui District of Shanghai, China. ( 29921269 )
2018
11
Cost-effectiveness analysis of a school-based dental caries prevention program using fluoridated milk in Bangkok, Thailand. ( 29448929 )
2018
12
Dental caries-something to sink your teeth into. ( 29936960 )
2018
13
Dental caries and diabetes: A Belgian survey of patients with type 1 and type 2 diabetes. ( 29934226 )
2018
14
Dental caries: Research perspective. ( 29442078 )
2018
15
Dental caries and fluorosis among children in Lebanon. ( 29900915 )
2018
16
Oral health outcomes: the association of clinical and socio-dental indicators to evaluate dental caries in preschool children. ( 29412407 )
2018
17
Pathology-specific molecular profiles of saliva in patients with multiple dental caries-potential application for predictive, preventive and personalised medical services. ( 29896318 )
2018
18
Mutans Streptococci and Dental Caries: A New Statistical Modeling Approach. ( 29393143 )
2018
19
Protective psychosocial factors and dental caries in children and adolescents: a systematic review and meta-analysis. ( 29926978 )
2018
20
Dental caries in schoolchildren: influence of inattention, hyperactivity and executive functions. ( 29898021 )
2018
21
Healthy and cariogenic foods consumption and dental caries: A preschool-based cross-sectional study. ( 29878498 )
2018
22
Trends in dental caries in Indian children for the past 25 years. ( 29900916 )
2018
23
Pattern of dental caries in 3-6-year-old children using decayed, missing, filled surface index and hierarchical caries pattern system: A descriptive study. ( 29970625 )
2018
24
Relationship between parents' occupational characteristics and untreated dental caries in offspring: A population-based study of data from the Korean National Health and Nutrition Examination Survey, 2008-2015. ( 29392328 )
2018
25
Association of the Risk of Dental Caries and Polymorphism of MBL2 rs11003125 Gene in Iranian Adults. ( 29902796 )
2018
26
Dental caries in peoples of Xingu Indigenous Park, Brazil, 2007 and 2013. ( 29412349 )
2018
27
Dental caries and bacterial load in saliva and dental biofilm of type 1 diabetics on continuous subcutaneous insulin infusion. ( 29898180 )
2018
28
Assessment of prevalence of dental caries and the associated factors among patients attending dental clinic in Debre Tabor general hospital: a hospital-based cross-sectional study. ( 29973262 )
2018
29
Prevalence of dental caries among male students aged 15-17a8^years in southern Asir, Saudi Arabia. ( 29942105 )
2018
30
Water Fluoridation and Dental Caries in U.S. Children and Adolescents. ( 29900806 )
2018
31
The Effect of Chemically Modified Tetracycline-3 on the Progression of Dental Caries in Rats. ( 29408826 )
2018
32
Dental caries and their association with socioeconomic characteristics, oral hygiene practices and eating habits among preschool children in Abu Dhabi, United Arab Emirates - the NOPLAS project. ( 29884158 )
2018
33
The Association between Molar-Incisor Hypomineralization and Dental Caries with Socioeconomic Status as an Explanatory Variable in a Group of Finnish Children. ( 29941779 )
2018
34
Beyond Streptococcus mutans: clinical implications of the evolving dental caries aetiological paradigms and its associated microbiome. ( 29449651 )
2018
35
No consistent association found between dental caries and body mass index in children. ( 29930361 )
2018
36
Fluoride compounds in dental caries prophylaxis in children and adolescents a89 review of Polish literature ( 29417787 )
2017
37
Prevalence of dental caries in overweight school going children of 12-15 years in and around Jaipur city, Rajasthan, India ( 29417789 )
2017
38
Type 2 diabetes as a risk indicator for dental caries in Korean adults: the 2011-2012 Korea national health and nutrition examination survey. ( 28872812 )
2017
39
Association of MBL2 Gene Polymorphism with Dental Caries in Saudi Children. ( 27894112 )
2017
40
Risk factors and prevalence of dental fluorosis and dental caries in school children of North India. ( 28025807 )
2017
41
Trends in dental caries rates over 45 years (1971-2016) among schoolchildren in FlorianA^polis, southern Brazil. ( 28880993 )
2017
42
Low sugar nutrition policies and dental caries: A study of primary schools in South Auckland. ( 28073166 )
2017
43
Prevalence and severity of dental caries among public school students aged 16-l8 in Hai'l, Kingdom of Saudi Arabia. ( 28936152 )
2017
44
Assessment of dental caries, oral hygiene status, traumatic dental injuries and provision of basic oral health care among visually impaired children of Eastern Odisha. ( 28914238 )
2017
45
The impact of MUC5B gene on dental caries. ( 28944591 )
2017
46
Association between socio-economic status and dental caries in elderly people in Sichuan Province, China: a cross-sectional study. ( 28947446 )
2017
47
Effects of Caesalpinia sappan on pathogenic bacteria causing dental caries and gingivitis. ( 29332889 )
2017
48
Parents' online discussions about children's dental caries: A critical content analysis. ( 28910248 )
2017
49
Relationship between Risk Behavior for Eating Disorders and Dental Caries and Dental Erosion. ( 29423431 )
2017
50
Feeding frequency in infancy and dental caries in childhood: a prospective cohort study. ( 28868798 )
2017

Variations for Dental Caries

Expression for Dental Caries

Search GEO for disease gene expression data for Dental Caries.

Pathways for Dental Caries

Pathways related to Dental Caries according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.38 CST1 HTN1 LPO MUC7 PRH1 PRH2

GO Terms for Dental Caries

Cellular components related to Dental Caries according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 CA6 CST1 FGF10 LPO LTF LYZL2
2 extracellular region GO:0005576 9.47 AMELX CA6 CST1 DSPP ENAM FGF10
3 other organism cell membrane GO:0044218 8.96 LTF MUC7

Biological processes related to Dental Caries according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.62 HTN1 LPO LTF STATH
2 ossification GO:0001503 9.54 DSPP LTF STATH
3 odontogenesis of dentin-containing tooth GO:0042475 9.43 AMELX ENAM FGF10
4 negative regulation of cysteine-type endopeptidase activity GO:2000117 9.4 CST1 LTF
5 killing of cells of other organism GO:0031640 9.33 HTN1 LTF MUC7
6 detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 9.26 CA6 CST1 LPO TAS2R38
7 biomineral tissue development GO:0031214 9.17 AMELX DSPP ENAM HTN1 STATH TFIP11

Molecular functions related to Dental Caries according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydroxyapatite binding GO:0046848 8.96 AMELX STATH
2 structural constituent of tooth enamel GO:0030345 8.92 AMELX ENAM STATH TUFT1

Sources for Dental Caries

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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