MCID: DNT012
MIFTS: 52

Dental Caries

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Dental Caries

MalaCards integrated aliases for Dental Caries:

Name: Dental Caries 12 77 56 45 15 17 74
Dental Caries Extending into Pulp 12
Dental Caries of Smooth Surface 12
Dental Caries Pit and Fissure 12
Smooth Surface Dental Caries 17

Classifications:



External Ids:

Disease Ontology 12 DOID:216
MeSH 45 D003731
NCIt 51 C52593
SNOMED-CT 69 80967001
ICD10 34 K02 K02.6 K02.9

Summaries for Dental Caries

MalaCards based summary : Dental Caries, also known as dental caries extending into pulp, is related to root caries and aplasia of lacrimal and salivary glands, and has symptoms including snoring and halitosis. An important gene associated with Dental Caries is DSPP (Dentin Sialophosphoprotein), and among its related pathways/superpathways is Salivary secretion. The drugs Salicylic acid and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include testes, breast and heart, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 77 Tooth decay, also known as dental caries or cavities, is a breakdown of teeth due to acids made by... more...

Related Diseases for Dental Caries

Diseases related to Dental Caries via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 150)
# Related Disease Score Top Affiliating Genes
1 root caries 33.1 CD79A DSPP LTF
2 aplasia of lacrimal and salivary glands 31.9 DSPP FGF10 LPO LTF
3 dental fluorosis 31.2 AMELX DSPP
4 dentin caries 11.9
5 enamel caries 11.5
6 tricho-dento-osseous syndrome 1 11.3
7 periapical periodontitis 11.3
8 flynn-aird syndrome 11.2
9 cockayne syndrome a 11.2
10 cutis laxa, autosomal recessive, type iia 11.2
11 insensitivity to pain, congenital, with anhidrosis 11.2
12 osteopetrosis, autosomal recessive 1 11.2
13 benjamin syndrome 11.2
14 dominant dystrophic epidermolysis bullosa 11.2
15 recessive dystrophic epidermolysis bullosa-generalized other 11.2
16 odontoclasia 10.8
17 periodontal disease 10.8
18 gingivitis 10.7
19 body mass index quantitative trait locus 1 10.6
20 periodontitis 10.5
21 diabetes mellitus 10.5
22 asthma 10.4
23 down syndrome 10.4
24 cerebral palsy 10.4
25 cleft lip 10.4
26 anxiety 10.3
27 cleft lip/palate 10.3
28 amelogenesis imperfecta, type iiia 10.3 AMELX ENAM
29 parotitis 10.3 CD79A LTF
30 attention deficit-hyperactivity disorder 10.3
31 pol iii-related leukodystrophies 10.3
32 dental pulp calcification 10.2 DSPP ENAM
33 tooth erosion 10.2 DSPP TUFT1
34 amelogenesis imperfecta, hypoplastic/hypomaturation, x-linked 2 10.2 AMELX TUFT1
35 dental pulp necrosis 10.2 AMELX DSPP
36 amelogenesis imperfecta, type ie 10.2 AMELX TUFT1
37 hypercementosis 10.2 DSPP ENAM
38 schizophrenia 10.2
39 diabetes mellitus, insulin-dependent 10.2
40 sjogren syndrome 10.2
41 chronic ethmoiditis 10.2 MUC5B MUC7
42 cystic fibrosis 10.1
43 ocular motor apraxia 10.1
44 allergic rhinitis 10.1
45 rhinitis 10.1
46 kidney disease 10.1
47 hypocalcified amelogenesis imperfecta 10.1 DSPP ENAM TUFT1
48 neurofibromatosis, type iv, of riccardi 10.1
49 autism 10.1
50 chronic kidney failure 10.1

Comorbidity relations with Dental Caries via Phenotypic Disease Network (PDN): (show all 13)


Acute Apical Periodontitis Acute Cystitis
Acute Pericementitis Alzheimer Disease
Aortic Valve Disease 1 Deficiency Anemia
Familial Atrial Fibrillation Gingivitis
Heart Disease Ischemic Heart Disease
Periodontitis, Chronic Periodontosis
Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Dental Caries:



Diseases related to Dental Caries

Symptoms & Phenotypes for Dental Caries

UMLS symptoms related to Dental Caries:


snoring, halitosis

GenomeRNAi Phenotypes related to Dental Caries according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00381-A-1 9.4 CD79A LTF TAS1R2 TUFT1
2 Decreased viability GR00381-A-3 9.4 CD79A LTF TAS1R2 TUFT1
3 Decreased viability GR00402-S-2 9.4 CD79A LTF TAS1R2 TUFT1

Drugs & Therapeutics for Dental Caries

Drugs for Dental Caries (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 632)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Salicylic acid Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 69-72-7 338
2
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 62-31-7, 51-61-6 681
3
Methamphetamine Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 537-46-2 10836
4
Emtricitabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 143491-57-0 60877
5
Abacavir Approved, Investigational Phase 4,Phase 2 136470-78-5 441300 65140
6
Dolutegravir Approved Phase 4,Phase 3 1051375-16-6 54726191
7
Lamivudine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 134678-17-4 60825
8
Efavirenz Approved, Investigational Phase 4,Phase 2,Not Applicable 154598-52-4 64139
9 sodium fluoride Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 7681-49-4
10
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 22916-47-8 4189
11
Eugenol Approved Phase 4,Not Applicable 97-53-0 3314
12
Zinc Approved, Investigational Phase 4,Phase 3,Not Applicable 7440-66-6 32051
13
Zinc oxide Approved Phase 4,Not Applicable 1314-13-2
14
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 55-56-1 2713 9552079
15
Sorbitol Approved Phase 4,Phase 2,Phase 3,Not Applicable 50-70-4 5780
16
Ethanol Approved Phase 4,Phase 1,Phase 2,Not Applicable 64-17-5 702
17
Midazolam Approved, Illicit Phase 4,Phase 1 59467-70-8 4192
18
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
19
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
20
Enfuvirtide Approved, Investigational Phase 4,Not Applicable 159519-65-0 16130199
21 Pinaverium Approved Phase 4 59995-65-2
22
Peginterferon alfa-2b Approved Phase 4,Phase 2 99210-65-8, 215647-85-1
23
Ribavirin Approved Phase 4,Phase 2,Not Applicable 36791-04-5 37542
24
Peginterferon alfa-2a Approved, Investigational Phase 4,Phase 2 198153-51-4 5360545
25
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
26
Chloramphenicol succinate Approved Phase 4 3544-94-3
27
Chloramphenicol Approved, Vet_approved Phase 4 56-75-7 298 5959
28
Rosiglitazone Approved, Investigational Phase 4 122320-73-4 77999
29
Regadenoson Approved, Investigational Phase 4 313348-27-5 219024
30
Adenosine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 58-61-7 60961
31
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 1 76-42-6 5284603
32
Tapentadol Approved Phase 4 175591-23-8 9838022
33
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
34
Irbesartan Approved, Investigational Phase 4 138402-11-6 3749
35
Atorvastatin Approved Phase 4,Phase 1 134523-00-5 60823
36
Indapamide Approved Phase 4 26807-65-8 3702
37
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 1,Phase 2 148553-50-8 5486971
38
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 1,Not Applicable 16590-41-3 5360515
39
Thymol Approved Phase 4,Not Applicable 89-83-8 6989
40
Spironolactone Approved Phase 4 52-01-7, 1952-01-7 5833
41
Morphine Approved, Investigational Phase 4 57-27-2 5288826
42
Calcium Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 7440-70-2 271
43
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4 1406-16-2
44
Vitamin D3 Approved, Nutraceutical Phase 4 67-97-0 5280795 6221
45
Creatine Approved, Investigational, Nutraceutical Phase 4,Not Applicable 57-00-1 586
46
Tenofovir Experimental, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 147127-20-6 464205
47
Imidacloprid Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 105827-78-9 86418
48
2,4-thiazolidinedione Investigational Phase 4 2295-31-0
49 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
50 Fluorides Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 1161)
# Name Status NCT ID Phase Drugs
1 Dental Caries Management by Risk Assessment: Identification and Treatment of Risk Factors Among (IDF) Personnel Unknown status NCT01142440 Phase 4
2 Elmex Gel Efficacy in Preventing White Spot Lesions Unknown status NCT00268138 Phase 4 elmex gel
3 Consumption Effect of Probiotic Products on Salivary Cariogenic Bacterial Counts in Preschool Children. Unknown status NCT02692625 Phase 4
4 Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2). Unknown status NCT01778699 Phase 4
5 Measles-Rubella Vaccine Immunogenicity at 6 and 9 Months of Age Unknown status NCT03071575 Phase 4
6 Effectiveness and Economic Evaluation of Glass Ionomer Material Using as Dental Sealant Unknown status NCT03034837 Phase 4 resin sealant;ART sealant
7 Efficacy of Calcium Silicate Pulp-capping; a Randomized Controlled Clinical Trial Unknown status NCT02201641 Phase 4
8 Efavirenz to Dolutegravir Switch in Patients With CNS Toxicity Unknown status NCT02285374 Phase 4 Dolutegravir, efavirenz, efavirenz/emtricitabine/tenofovir
9 Prevention of Dental Caries Lesions With Fluoride Varnish in Erupting First Permanent Molars Completed NCT02592278 Phase 4 Fluoride Varnish;Control Group
10 Fluoride Varnish For Childsmile Nursery School Attenders Completed NCT01674933 Phase 4 Duraphat® Fluoride Varnish
11 Use of Fissure Sealants on Primary Molars Completed NCT01438866 Phase 4
12 Therapeutic Effect of Two Fluoride Varnishes on White Spot Lesions: a Clinical Study Completed NCT00723515 Phase 4 sodium fluoride;sodium fluoride calcium fluoride
13 Indirect Pulp Treatment in Primary Molars Completed NCT03770871 Phase 4 Dycal (Indirect pulp treatment);Vitrebond (Indirect pulp treatment)
14 Impact of Maternal Xylitol Consumption on Mutans Sterptococci Completed NCT02036151 Phase 4 xylitol;fluoride varnish application
15 Preventive and Therapeutic Proximal Sealants Completed NCT02338180 Phase 4
16 Impact of Fluoride Vanish Application in Dental Prevention for Elderly Completed NCT01038817 Phase 4 Duraphat
17 The Effect of Silver Diamine Fluoride (SDF) on Bacteria Involved in Root or Cervical Carious Lesions Completed NCT02953886 Phase 4
18 Effect of the Amount of Fluoride Toothpaste on Fluoride Availability in the Oral Fluids in Children Completed NCT03455621 Phase 4
19 Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment Completed NCT02447289 Phase 4 Intranasal ketamine;Oral ketamine;Intranasal midazolam;Oral midazolam
20 Fuji Type VII Sealant Versus Resin Based Sealant. A Clinical Trial Completed NCT02795728 Phase 4
21 Comparison of the Effect of Fluoride Remineralizer Gel and Foam Completed NCT02490592 Phase 4
22 Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients Completed NCT01768390 Phase 4
23 Postoperative Pulpal Complications in Posterior Resin Composite Restorations Without Glass-ionomer Cement Lining Completed NCT01567514 Phase 4
24 Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride Completed NCT01563172 Phase 4 Sodium fluoride / silica and carbopol, 0.5g;Sodium fluoride / silica and carbopol, 1.5g;Sodium fluoride / silica and carbopol, 1.5g
25 Enamel Remineralization Potential of Dentifrices in Situ Completed NCT01128946 Phase 4 NaF;SnF;NaMFP
26 BiodentineTM Versus Formocresol Pulpotomy Technique in Primary Molars Completed NCT03779698 Phase 4 Formocresol
27 MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization Study Completed NCT02424097 Phase 4 CPP-ACP 5% sodium fluoride varnish & 900ppm fluoride paste;1,100pm F-toothpaste and 0.5%NaF rinse
28 Interaction Between Chlorhexidine and Fluoride Completed NCT02935322 Phase 4 0.12 % chlorhexidine + 0.2 % NaF mouthrinse;0.2 % NaF mouthrinse;0.12% chlorhexidine
29 Bifidobacterium Lactis BB12 and Xylitol Delivered With a Novel Slow-release Pacifier Completed NCT00638677 Phase 4
30 Efficacy of Moderate Sedation for Dental Treatment of Young Children Completed NCT00902395 Phase 4 Midazolam;Midazolam, ketamine
31 Comparison of Topical Analgesic With Saline Rinses in Post Extraction Healing Completed NCT02921165 Phase 4 analgesic mouth rinses (dissolved Aspirin);Normal saline rinses.
32 A Study to Evaluate of the Efficacy of Enfuvirtide During the Induction Phase of Therapy Completed NCT00344760 Phase 4 Enfuvirtide;Efavirenz, lamivudine, and tenofovir
33 Pinverin Application Trial to Reduce Bowel Uptake of FDG (Fluorodeoxyglucose) Completed NCT02173964 Phase 4 pinaverium bromide;water
34 Effects of Two Sugar Substituted Chewing Gums on Caries and Gingivitis Variables Completed NCT01578603 Phase 4
35 Remineralisation of White Spot Lesions by Elmex® gelée in Post-orthodontic Patients Completed NCT01329731 Phase 4 elmex® gelée;negative control (placebo)
36 Different PEG-interferon and Ribavirin Schedules for Chronic Hepatitis C in the Real Clinical Practice. Completed NCT01195181 Phase 4 peginterferon plus ribavirin
37 MI Varnish for the Prevention of White Spot Lesions Completed NCT03446690 Phase 4 MI Varnish
38 Treatment of Immature Permanent Teeth With Three Different Pulp Capping Materials With Partial Pulpotomy Completed NCT03426046 Phase 4 Pulp Capping Agents
39 Antimicrobial Pulpotomy of Primary Molars Completed NCT01010451 Phase 4
40 Evaluation of Silica-calcium Phosphate Composite in Socket Augmentation Completed NCT03897010 Phase 4
41 Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study Completed NCT01601145 Phase 4
42 Music Distraction Strategy in Children Dental Care Completed NCT02489812 Phase 4
43 Effect of Rosiglitazone Versus Placebo on Cardiovascular Performance and Myocardial Triglyceride Completed NCT00424762 Phase 4 rosiglitazone;placebo
44 Oral Fluoride Bioavailability by the Consumption of Meals Prepared With Fluoridated Water or Salt Completed NCT02776280 Phase 4
45 Regadenoson Blood Flow in Type 1 Diabetes (RABIT1D) Completed NCT01019486 Phase 4 Regadenoson myocardial perfusion imaging;Regadenoson MRI myocardial blood flow
46 Dental Fluorosis Risk by the Use of Acidulated Fluoride Dentifrice Completed NCT03761485 Phase 4
47 Safety and Immunogenicity of 1 or 2 Doses of IPV in Latin American Infants Primed With Bivalent OPV Vaccine Completed NCT01831050 Phase 4
48 Comparison of the Effects of Tapentadol and Oxycodone on Gastrointestinal and Colonic Transit in Humans Completed NCT01500317 Phase 4 Tapentadol;Oxycodone;Placebo
49 A Pharmacodynamic Study to Evaluate Neutrophil Distribution Kinetics and Function Following Single-Dose RoActemra/Actemra (Tocilizumab) in Healthy Volunteers Completed NCT01991990 Phase 4 placebo;tocilizumab [RoActemra/Actemra]
50 Renal Denervation in Diabetic Nephropathy Completed NCT01588795 Phase 4 Standardized antiproteinuric medication regimen includes an angiotensin receptor blocker , a diuretic , 25OH vitamin D3 and a statin

Search NIH Clinical Center for Dental Caries

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: dental caries

Genetic Tests for Dental Caries

Anatomical Context for Dental Caries

MalaCards organs/tissues related to Dental Caries:

42
Testes, Breast, Heart, Lung, Bone, Prostate, Salivary Gland

Publications for Dental Caries

Articles related to Dental Caries:

(show top 50) (show all 3075)
# Title Authors Year
1
Performing together: Monozygotic twin comedians/Twin research: Mirror-image cleft lip and palate; dental caries; noninvasive prenatal testing; Capgras syndrome with folie à Deux/In the news: athletic twins; transgendered twins; crib-sharing; common careers. ( 30739630 )
2019
2
Microbial Profile and Dental Caries in Cleft Lip and Palate Babies Between 0 and 3 Years Old. ( 29800530 )
2019
3
Effects of Lactobacillus salivarius WB21 combined with green tea catechins on dental caries, periodontitis, and oral malodor. ( 30530235 )
2019
4
Toward dental caries: Exploring nanoparticle-based platforms and calcium phosphate compounds for dental restorative materials. ( 30582079 )
2019
5
Preliminary study of the oral mycobiome of children with and without dental caries. ( 30598729 )
2019
6
The Minamata Convention on Mercury and its implications for management of dental caries in low- and middle-income countries. ( 30600531 )
2019
7
Bayesian model with application to a study of dental caries. ( 30616542 )
2019
8
Dental caries on CT in the ER population: prevalence and reporting practices. ( 30617934 )
2019
9
Optical pH measurement system using a single fluorescent dye for assessing susceptibility to dental caries. ( 30623630 )
2019
10
Dental caries and associated factors in 3 to 5-year-old children in Zhejiang Province, China: an epidemiological survey. ( 30630468 )
2019
11
Assessment of dental caries and salivary nitric oxide levels in children with dyspepsia. ( 30634964 )
2019
12
Acquisition of Streptococcus mutans and dental caries experience in pediatric sickle cell anaemia patients under various prophylactic therapies. ( 30637684 )
2019
13
Dental caries status of Lisu preschool children in Yunnan Province, China: a cross-sectional study. ( 30646886 )
2019
14
Salivary characteristics and dental caries experience in remote Indigenous children in Australia: a cross-sectional study. ( 30654791 )
2019
15
The influence of orthodontic treatment on dental caries: An Australian cohort study. ( 30656705 )
2019
16
Identifying and critically examining government legislation relevant to children's dental caries in Calgary, Alberta, Canada: a health inequities lens. ( 30663768 )
2019
17
How much does household food insecurity explain income inequalities in untreated dental caries? ( 30664294 )
2019
18
Metagenome sequencing-based strain-level and functional characterization of supragingival microbiome associated with dental caries in children. ( 30671194 )
2019
19
Oral health behavior of children and guardians' beliefs about children's dental caries in Vientiane, Lao People's Democratic Republic (Lao PDR). ( 30682133 )
2019
20
Association between exposure to household smoking and dental caries in preschool children: a cross-sectional study. ( 30684963 )
2019
21
Association Between Water Fluoridation and Income-Related Dental Caries of US Children and Adolescents. ( 30688985 )
2019
22
Dental caries are positively associated with periodontal disease severity. ( 30693397 )
2019
23
Diagnodent and VistaCam may be unsuitable for the evaluation of dental caries in archeological teeth. ( 30693947 )
2019
24
Correlation between Dermatoglyphics, Dental Caries and Salivary pH: An Invivo Study. ( 30700961 )
2019
25
Probiotics as an Adjunct Therapy for the Treatment of Halitosis, Dental Caries and Periodontitis. ( 30729452 )
2019
26
Prolonged Breastfeeding and Dental Caries In Children In the Third Year of Life. ( 30730796 )
2019
27
WITHDRAWN: Ozone therapy for the treatment of dental caries. ( 30731019 )
2019
28
Dental caries among childhood cancer survivors. ( 30732142 )
2019
29
Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting. ( 30736404 )
2019
30
Analysis of Calcium Levels in Groundwater and Dental Caries in the Coastal Population of an Archipelago Country. ( 30740177 )
2019
31
Dental Caries and Vitamin D Status among Children in Asia: A literature review. ( 30740822 )
2019
32
MUC7 Level As A New Saliva Risk Factor For Dental Caries In Adult Patients. ( 30745804 )
2019
33
MMP13 Contributes to Dental Caries Associated with Developmental Defects of Enamel. ( 30759432 )
2019
34
Impact of the radiographic method on treatment decisions related to dental caries in primary molars: a before-after study. ( 30778687 )
2019
35
Cross-sectional study of the association between serum perfluorinated alkyl acid concentrations and dental caries among US adolescents (NHANES 1999-2012). ( 30782897 )
2019
36
Maternal perception about child oral health is associated to child dental caries and to maternal self-report about oral health. ( 30789085 )
2019
37
Modifying dietary risk behaviors to prevent obesity and dental caries in very young children: results of the Baby Steps to Health pediatric dental pilot. ( 30801726 )
2019
38
Dental caries lesions in primary teeth without obvious cavitation: treatment decision-making process. ( 30803096 )
2019
39
Association of ENAM, TUFT1, MMP13, IL1B, IL10 and IL1RN gene polymorphism and dental caries susceptibility in Chinese children. ( 30803280 )
2019
40
Dental caries experience in relation to body mass index and anthropometric measurements of rural children of Nellore district: A cross-sectional study. ( 30804302 )
2019
41
Assessment of Intelligence Quotient using Raven's Coloured Progressive Matrices among school children of Hyderabad Karnataka region and its correlation with prevalence of dental caries. ( 30804304 )
2019
42
Vitamin D3 and Dental Caries in Children with Growth Hormone Deficiency. ( 30804998 )
2019
43
Is the caregivers' oral health related to dental caries in children or adolescents? A systematic review. ( 30810802 )
2019
44
Is there association between chronic kidney disease and dental caries? A case-controlled study. ( 30818314 )
2019
45
Saliva as a biomarker for dental caries: A systematic review. ( 30820074 )
2019
46
Cranberry Polyphenols: Natural Weapons against Dental Caries. ( 30823634 )
2019
47
Fluoride toothpastes of different concentrations for preventing dental caries. ( 30829399 )
2019
48
Prevention of Dental Caries by Silver Diamine Fluoride. ( 30829497 )
2019
49
Protocols to Study Dental Caries In Vitro: Microbial Caries Models. ( 30838590 )
2019
50
Protocols to Study Dental Caries In Vitro: pH Cycling Models. ( 30838592 )
2019

Variations for Dental Caries

Expression for Dental Caries

Search GEO for disease gene expression data for Dental Caries.

Pathways for Dental Caries

Pathways related to Dental Caries according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.44 DMBT1 HTN1 LPO MUC5B MUC7 PRH1

GO Terms for Dental Caries

Cellular components related to Dental Caries according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.86 CA6 DMBT1 FGF10 LPO LTF MUC5B
2 extracellular region GO:0005576 9.5 AMELX CA6 DMBT1 DSPP ENAM FGF10
3 extracellular matrix GO:0031012 9.35 AMELX DMBT1 DSPP ENAM TFIP11
4 other organism cell membrane GO:0044218 9.16 LTF MUC7

Biological processes related to Dental Caries according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.71 HTN1 LPO LTF STATH
2 cellular protein metabolic process GO:0044267 9.67 AMELX DMBT1 ENAM LTF
3 ossification GO:0001503 9.63 DSPP LTF STATH
4 defense response to Gram-negative bacterium GO:0050829 9.61 DMBT1 LTF LYZL2
5 odontogenesis of dentin-containing tooth GO:0042475 9.5 AMELX ENAM FGF10
6 detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 9.33 CA6 LPO TAS2R38
7 positive regulation of enamel mineralization GO:0070175 9.26 DSPP ENAM
8 biomineral tissue development GO:0031214 9.17 AMELX DSPP ENAM HTN1 STATH TFIP11
9 killing of cells of other organism GO:0031640 9.13 HTN1 LTF MUC7

Molecular functions related to Dental Caries according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydroxyapatite binding GO:0046848 8.96 AMELX STATH
2 structural constituent of tooth enamel GO:0030345 8.92 AMELX ENAM STATH TUFT1
3 protein binding GO:0005515 10.06 AMELX CA6 CD79A DMBT1 DSPP ENAM

Sources for Dental Caries

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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