MCID: DNT012
MIFTS: 51

Dental Caries

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Dental Caries

MalaCards integrated aliases for Dental Caries:

Name: Dental Caries 12 76 55 44 15 73
Dental Caries Extending into Pulp 12
Dental Caries of Smooth Surface 12
Dental Caries Pit and Fissure 12

Classifications:



External Ids:

Disease Ontology 12 DOID:216
ICD10 33 K02 K02.6 K02.9
MeSH 44 D003731
NCIt 50 C52593
SNOMED-CT 68 80967001

Summaries for Dental Caries

MalaCards based summary : Dental Caries, also known as dental caries extending into pulp, is related to root caries and aplasia of lacrimal and salivary glands, and has symptoms including snoring and halitosis. An important gene associated with Dental Caries is DSPP (Dentin Sialophosphoprotein), and among its related pathways/superpathways is Salivary secretion. The drugs Salicylic acid and Efavirenz have been mentioned in the context of this disorder. Affiliated tissues include bone, salivary gland and heart, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 76 Tooth decay, also known as dental caries or cavities, is a breakdown of teeth due to acids made by... more...

Related Diseases for Dental Caries

Diseases related to Dental Caries via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 115)
# Related Disease Score Top Affiliating Genes
1 root caries 33.0 CD79A DSPP LTF
2 aplasia of lacrimal and salivary glands 31.8 DSPP FGF10 LPO LTF
3 dental fluorosis 31.1 AMELX DSPP
4 dentin caries 11.9
5 enamel caries 11.4
6 periapical periodontitis 11.3
7 tricho-dento-osseous syndrome 1 11.3
8 flynn-aird syndrome 11.1
9 cockayne syndrome a 11.1
10 cutis laxa, autosomal recessive, type iia 11.1
11 insensitivity to pain, congenital, with anhidrosis 11.1
12 osteopetrosis, autosomal recessive 1 11.1
13 benjamin syndrome 11.1
14 dominant dystrophic epidermolysis bullosa 11.1
15 recessive dystrophic epidermolysis bullosa-generalized other 11.1
16 odontoclasia 10.8
17 periodontal disease 10.7
18 body mass index quantitative trait locus 1 10.6
19 periodontitis 10.4
20 diabetes mellitus 10.4
21 gingivitis 10.4
22 down syndrome 10.3
23 cerebral palsy 10.3
24 asthma 10.2
25 cleft lip 10.2
26 cleft lip/palate 10.2
27 amelogenesis imperfecta, type iiia 10.2 AMELX ENAM
28 anxiety 10.2
29 parotitis 10.2 CD79A LTF
30 amelogenesis imperfecta, hypoplastic/hypomaturation, x-linked 2 10.2 AMELX TUFT1
31 tooth erosion 10.2 DSPP TUFT1
32 dental pulp necrosis 10.2 AMELX DSPP
33 dental pulp calcification 10.2 DSPP ENAM
34 amelogenesis imperfecta, type ie 10.2 AMELX TUFT1
35 schizophrenia 10.1
36 cystic fibrosis 10.1
37 hypercementosis 10.1 DSPP ENAM
38 hypocalcified amelogenesis imperfecta 10.1 DSPP ENAM TUFT1
39 attention deficit-hyperactivity disorder 10.1
40 diabetes mellitus, insulin-dependent 10.1
41 sjogren syndrome 10.1
42 allergic rhinitis 10.1
43 hyperglycemia 10.1
44 rhinitis 10.1
45 tooth resorption 10.1 AMELX DSPP
46 teeth hard tissue disease 10.0 AMELX DSPP ENAM TUFT1
47 graft-versus-host disease 10.0
48 hemangioma 10.0
49 endocarditis 10.0
50 epilepsy 10.0

Comorbidity relations with Dental Caries via Phenotypic Disease Network (PDN): (show all 13)


Acute Apical Periodontitis Acute Cystitis
Acute Pericementitis Alzheimer Disease
Aortic Valve Disease 1 Deficiency Anemia
Familial Atrial Fibrillation Gingivitis
Heart Disease Ischemic Heart Disease
Periodontitis, Chronic Periodontosis
Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Dental Caries:



Diseases related to Dental Caries

Symptoms & Phenotypes for Dental Caries

UMLS symptoms related to Dental Caries:


snoring, halitosis

GenomeRNAi Phenotypes related to Dental Caries according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00240-S-1 10.51 DMBT1 DSPP
2 Decreased viability GR00381-A-1 10.51 CD79A CST1 DSPP LTF MUC7 TAS1R2
3 Decreased viability GR00381-A-3 10.51 CD79A LTF TAS1R2 TUFT1
4 Decreased viability GR00402-S-2 10.51 AMELX CA6 CD79A CST1 DMBT1 DSPP
5 no effect GR00402-S-1 9.62 AMELX CA6 CD79A CST1 DMBT1 DSPP
6 Increased gamma-H2AX phosphorylation GR00053-A 9.56 CD79A CST1 DSPP HTN1 LTF MUC7

Drugs & Therapeutics for Dental Caries

Drugs for Dental Caries (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 597)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Salicylic acid Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 69-72-7 338
2
Efavirenz Approved, Investigational Phase 4,Phase 2,Not Applicable 154598-52-4 64139
3
Lamivudine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 134678-17-4 60825
4
Emtricitabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 143491-57-0 60877
5 Dolutegravir Approved Phase 4,Phase 3 1051375-16-6 54726191
6
Abacavir Approved, Investigational Phase 4,Phase 2 136470-78-5 65140 441300
7 sodium fluoride Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 7681-49-4
8
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 22916-47-8 4189
9
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-61-6, 62-31-7 681
10
Methamphetamine Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 537-46-2 10836
11
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 55-56-1 2713 9552079
12
Sorbitol Approved Phase 4,Phase 2,Phase 3,Not Applicable 50-70-4 5780
13
Ethanol Approved Phase 4,Phase 1,Phase 2,Not Applicable 64-17-5 702
14
Zinc Approved, Investigational Phase 4,Phase 3,Not Applicable 7440-66-6
15
Zinc oxide Approved Phase 4,Not Applicable 1314-13-2
16
Eugenol Approved Phase 4,Not Applicable 97-53-0 3314
17
Midazolam Approved, Illicit Phase 4,Phase 1 59467-70-8 4192
18
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
19
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
20
Enfuvirtide Approved, Investigational Phase 4,Not Applicable 159519-65-0 16130199
21 Pinaverium Approved Phase 4 59995-65-2
22
Ribavirin Approved Phase 4,Phase 2,Not Applicable 36791-04-5 37542
23
Peginterferon alfa-2a Approved, Investigational Phase 4,Phase 2 198153-51-4 5360545
24
Peginterferon alfa-2b Approved Phase 4,Phase 2 99210-65-8, 215647-85-1
25
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
26
Chloramphenicol Approved, Vet_approved Phase 4 56-75-7 5959 298
27
Rosiglitazone Approved, Investigational Phase 4 122320-73-4 77999
28
Regadenoson Approved, Investigational Phase 4 313348-27-5 219024
29
Adenosine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 58-61-7 60961
30
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 1 76-42-6 5284603
31
Indapamide Approved Phase 4 26807-65-8 3702
32
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
33
Irbesartan Approved, Investigational Phase 4 138402-11-6 3749
34
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 1,Phase 2 148553-50-8 5486971
35
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 1 16590-41-3 5360515
36
Thymol Approved Phase 4,Not Applicable 89-83-8 6989
37
Spironolactone Approved Phase 4 52-01-7, 1952-01-7 5833
38
Morphine Approved, Investigational Phase 4 57-27-2 5288826
39
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4 1406-16-2
40
Vitamin D3 Approved, Nutraceutical Phase 4 67-97-0 5280795 6221
41
Creatine Approved, Investigational, Nutraceutical Phase 4,Not Applicable 57-00-1 586
42
Tenofovir Experimental, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 147127-20-6 464205
43
Chloramphenicol succinate Experimental Phase 4 3544-94-3
44
2,4-thiazolidinedione Investigational Phase 4 2295-31-0
45 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
46 Fluorides Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
47 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
48 Olaflur Phase 4,Not Applicable
49 Cariostatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
50 Acidophilus Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 1127)
# Name Status NCT ID Phase Drugs
1 Dental Caries Management by Risk Assessment: Identification and Treatment of Risk Factors Among (IDF) Personnel Unknown status NCT01142440 Phase 4
2 Elmex Gel Efficacy in Preventing White Spot Lesions Unknown status NCT00268138 Phase 4 elmex gel
3 Consumption Effect of Probiotic Products on Salivary Cariogenic Bacterial Counts in Preschool Children. Unknown status NCT02692625 Phase 4
4 Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2). Unknown status NCT01778699 Phase 4
5 Effectiveness and Economic Evaluation of Glass Ionomer Material Using as Dental Sealant Unknown status NCT03034837 Phase 4 resin sealant;ART sealant
6 Efavirenz to Dolutegravir Switch in Patients With CNS Toxicity Unknown status NCT02285374 Phase 4 Dolutegravir, efavirenz, efavirenz/emtricitabine/tenofovir
7 Prevention of Dental Caries Lesions With Fluoride Varnish in Erupting First Permanent Molars Completed NCT02592278 Phase 4 Fluoride Varnish;Control Group
8 Fluoride Varnish For Childsmile Nursery School Attenders Completed NCT01674933 Phase 4 Duraphat® Fluoride Varnish
9 Use of Fissure Sealants on Primary Molars Completed NCT01438866 Phase 4
10 Therapeutic Effect of Two Fluoride Varnishes on White Spot Lesions: a Clinical Study Completed NCT00723515 Phase 4 sodium fluoride;sodium fluoride calcium fluoride
11 Indirect Pulp Treatment in Primary Molars Completed NCT03770871 Phase 4 Dycal (Indirect pulp treatment);Vitrebond (Indirect pulp treatment)
12 Impact of Maternal Xylitol Consumption on Mutans Sterptococci Completed NCT02036151 Phase 4 xylitol;fluoride varnish application
13 Preventive and Therapeutic Proximal Sealants Completed NCT02338180 Phase 4
14 Impact of Fluoride Vanish Application in Dental Prevention for Elderly Completed NCT01038817 Phase 4 Duraphat
15 The Effect of Silver Diamine Fluoride (SDF) on Bacteria Involved in Root or Cervical Carious Lesions Completed NCT02953886 Phase 4
16 Effect of the Amount of Fluoride Toothpaste on Fluoride Availability in the Oral Fluids in Children Completed NCT03455621 Phase 4
17 Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment Completed NCT02447289 Phase 4 Intranasal ketamine;Oral ketamine;Intranasal midazolam;Oral midazolam
18 Fuji Type VII Sealant Versus Resin Based Sealant. A Clinical Trial Completed NCT02795728 Phase 4
19 Comparison of the Effect of Fluoride Remineralizer Gel and Foam Completed NCT02490592 Phase 4
20 Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients Completed NCT01768390 Phase 4
21 Postoperative Pulpal Complications in Posterior Resin Composite Restorations Without Glass-ionomer Cement Lining Completed NCT01567514 Phase 4
22 Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride Completed NCT01563172 Phase 4 Sodium fluoride / silica and carbopol, 0.5g;Sodium fluoride / silica and carbopol, 1.5g;Sodium fluoride / silica and carbopol, 1.5g
23 Enamel Remineralization Potential of Dentifrices in Situ Completed NCT01128946 Phase 4 NaF;SnF;NaMFP
24 BiodentineTM Versus Formocresol Pulpotomy Technique in Primary Molars Completed NCT03779698 Phase 4 Formocresol
25 MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization Study Completed NCT02424097 Phase 4 CPP-ACP 5% sodium fluoride varnish & 900ppm fluoride paste;1,100pm F-toothpaste and 0.5%NaF rinse
26 Interaction Between Chlorhexidine and Fluoride Completed NCT02935322 Phase 4 0.12 % chlorhexidine + 0.2 % NaF mouthrinse;0.2 % NaF mouthrinse;0.12% chlorhexidine
27 Bifidobacterium Lactis BB12 and Xylitol Delivered With a Novel Slow-release Pacifier Completed NCT00638677 Phase 4
28 Efficacy of Moderate Sedation for Dental Treatment of Young Children Completed NCT00902395 Phase 4 Midazolam;Midazolam, ketamine
29 Comparison of Topical Analgesic With Saline Rinses in Post Extraction Healing Completed NCT02921165 Phase 4 analgesic mouth rinses (dissolved Aspirin);Normal saline rinses.
30 A Study to Evaluate of the Efficacy of Enfuvirtide During the Induction Phase of Therapy Completed NCT00344760 Phase 4 Enfuvirtide;Efavirenz, lamivudine, and tenofovir
31 Pinverin Application Trial to Reduce Bowel Uptake of FDG (Fluorodeoxyglucose) Completed NCT02173964 Phase 4 pinaverium bromide;water
32 Effects of Two Sugar Substituted Chewing Gums on Caries and Gingivitis Variables Completed NCT01578603 Phase 4
33 Remineralisation of White Spot Lesions by Elmex® gelée in Post-orthodontic Patients Completed NCT01329731 Phase 4 elmex® gelée;negative control (placebo)
34 Different PEG-interferon and Ribavirin Schedules for Chronic Hepatitis C in the Real Clinical Practice. Completed NCT01195181 Phase 4 peginterferon plus ribavirin
35 MI Varnish for the Prevention of White Spot Lesions Completed NCT03446690 Phase 4 MI Varnish
36 Treatment of Immature Permanent Teeth With Three Different Pulp Capping Materials With Partial Pulpotomy Completed NCT03426046 Phase 4 Pulp Capping Agents
37 Antimicrobial Pulpotomy of Primary Molars Completed NCT01010451 Phase 4
38 Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study Completed NCT01601145 Phase 4
39 Music Distraction Strategy in Children Dental Care Completed NCT02489812 Phase 4
40 Effect of Rosiglitazone Versus Placebo on Cardiovascular Performance and Myocardial Triglyceride Completed NCT00424762 Phase 4 rosiglitazone;placebo
41 Oral Fluoride Bioavailability by the Consumption of Meals Prepared With Fluoridated Water or Salt Completed NCT02776280 Phase 4
42 Regadenoson Blood Flow in Type 1 Diabetes (RABIT1D) Completed NCT01019486 Phase 4 Regadenoson myocardial perfusion imaging;Regadenoson MRI myocardial blood flow
43 Dental Fluorosis Risk by the Use of Acidulated Fluoride Dentifrice Completed NCT03761485 Phase 4
44 Safety and Immunogenicity of 1 or 2 Doses of IPV in Latin American Infants Primed With Bivalent OPV Vaccine Completed NCT01831050 Phase 4
45 Comparison of the Effects of Tapentadol and Oxycodone on Gastrointestinal and Colonic Transit in Humans Completed NCT01500317 Phase 4 Tapentadol;Oxycodone;Placebo
46 A Pharmacodynamic Study to Evaluate Neutrophil Distribution Kinetics and Function Following Single-Dose RoActemra/Actemra (Tocilizumab) in Healthy Volunteers Completed NCT01991990 Phase 4 placebo;tocilizumab [RoActemra/Actemra]
47 Renal Denervation in Diabetic Nephropathy Completed NCT01588795 Phase 4 Standardized antiproteinuric medication regimen includes an angiotensin receptor blocker , a diuretic , 25OH vitamin D3 and a statin
48 A Study Of Pregabalin (Lyrica) Drug Levels In Urine, Plasma And Breast Milk Of Healthy Lactating Women Completed NCT01727791 Phase 4 pregabalin (Lyrica)
49 Comparison of ACTIVA BioACTIVE Versus Compomer in Restoring Dental Decay in Primary Molar Teeth Recruiting NCT03516838 Phase 4 ACTIVA™ BioACTIVE;Compomer
50 Occlusal Caries Management in First Permanent Molars in Child Dental Care Recruiting NCT03315312 Phase 4 Fluoride Varnishes;Fissure Sealants

Search NIH Clinical Center for Dental Caries

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: dental caries

Genetic Tests for Dental Caries

Anatomical Context for Dental Caries

MalaCards organs/tissues related to Dental Caries:

41
Bone, Salivary Gland, Heart, Testes, Colon, Bone Marrow, Kidney

Publications for Dental Caries

Articles related to Dental Caries:

(show top 50) (show all 1574)
# Title Authors Year
1
Added Sugar and Dental Caries in Children: A Scientific Update and Future Steps. ( 30447790 )
2019
2
Redefining the Phenotype of Dental Caries. ( 29393149 )
2018
3
Inequalities in dental caries experience among 4-year-old New Zealand children. ( 29419880 )
2018
4
The Associations of School Oral Health-Related Environments with Oral Health Behaviours and Dental Caries in Children. ( 29393138 )
2018
5
Do Signs of Attention-Deficit/Hyperactivity Disorder Increase the Odds of Dental Caries? A Case-Control Study. ( 29393165 )
2018
6
Obesity and Dental Caries in Young Children in Plymouth, United Kingdom: A Spatial Analysis. ( 29380963 )
2018
7
Effect of inhaled medication on dental caries index in asthmatic children. ( 29402495 )
2018
8
Relations among obesity, family socioeconomic status, oral health behaviors, and dental caries in adolescents: the 2010-2012 Korea National Health and nutrition examination survey. ( 29929557 )
2018
9
Consortium genome-wide meta-analysis for childhood dental caries traits. ( 29931343 )
2018
10
Dental caries prevention strategies among children and adolescents with immigrantA - or low socioeconomic backgrounds- do they work? A systematic review. ( 29415706 )
2018
11
Deciduous dental caries status and associated risk factors among preschool children in Xuhui District of Shanghai, China. ( 29921269 )
2018
12
Cost-effectiveness analysis of a school-based dental caries prevention program using fluoridated milk in Bangkok, Thailand. ( 29448929 )
2018
13
Dental caries-something to sink your teeth into. ( 29936960 )
2018
14
Dental caries and diabetes: A Belgian survey of patients with type 1 and type 2 diabetes. ( 29934226 )
2018
15
Dental caries: Research perspective. ( 29442078 )
2018
16
Dental caries and fluorosis among children in Lebanon. ( 29900915 )
2018
17
Oral health outcomes: the association of clinical and socio-dental indicators to evaluate dental caries in preschool children. ( 29412407 )
2018
18
Pathology-specific molecular profiles of saliva in patients with multiple dental caries-potential application for predictive, preventive and personalised medical services. ( 29896318 )
2018
19
Mutans Streptococci and Dental Caries: A New Statistical Modeling Approach. ( 29393143 )
2018
20
Protective psychosocial factors and dental caries in children and adolescents: a systematic review and meta-analysis. ( 29926978 )
2018
21
Dental caries in schoolchildren: influence of inattention, hyperactivity and executive functions. ( 29898021 )
2018
22
Healthy and cariogenic foods consumption and dental caries: A preschool-based cross-sectional study. ( 29878498 )
2018
23
Trends in dental caries in Indian children for the past 25 years. ( 29900916 )
2018
24
Pattern of dental caries in 3-6-year-old children using decayed, missing, filled surface index and hierarchical caries pattern system: A descriptive study. ( 29970625 )
2018
25
Relationship between parents' occupational characteristics and untreated dental caries in offspring: A population-based study of data from the Korean National Health and Nutrition Examination Survey, 2008-2015. ( 29392328 )
2018
26
Association of the Risk of Dental Caries and Polymorphism of MBL2 rs11003125 Gene in Iranian Adults. ( 29902796 )
2018
27
Dental caries in peoples of Xingu Indigenous Park, Brazil, 2007 and 2013. ( 29412349 )
2018
28
Dental caries and bacterial load in saliva and dental biofilm of type 1 diabetics on continuous subcutaneous insulin infusion. ( 29898180 )
2018
29
Assessment of prevalence of dental caries and the associated factors among patients attending dental clinic in Debre Tabor general hospital: a hospital-based cross-sectional study. ( 29973262 )
2018
30
Prevalence of dental caries among male students aged 15-17a8^years in southern Asir, Saudi Arabia. ( 29942105 )
2018
31
Water Fluoridation and Dental Caries in U.S. Children and Adolescents. ( 29900806 )
2018
32
The Effect of Chemically Modified Tetracycline-3 on the Progression of Dental Caries in Rats. ( 29408826 )
2018
33
Dental caries and their association with socioeconomic characteristics, oral hygiene practices and eating habits among preschool children in Abu Dhabi, United Arab Emirates - the NOPLAS project. ( 29884158 )
2018
34
Allergic rhinitis, rather than asthma, is a risk factor for dental caries. ( 28585768 )
2018
35
A comparative evaluation of dental caries status and salivary properties of children aged 5-14 years undergoing treatment for acute lymphoblastic leukemia, type I diabetes mellitus, and asthma - In vivo. ( 30246751 )
2018
36
Salivary lead concentration in dental caries among normal and children with cerebral palsy. ( 30324929 )
2018
37
Microbial Profile and Dental Caries in Cleft Lip and Palate Babies Between 0 and 3 Years Old. ( 29800530 )
2018
38
Age-related heterogeneity in dental caries and associated risk factors in individuals with cystic fibrosis ages 6-20 years: A pilot study. ( 30005828 )
2018
39
Dental Caries in Chinese Elderly People: Findings from the 4th National Oral Health Survey. ( 30255172 )
2018
40
Silver diamine fluoride versus therapeutic sealants for the arrest and prevention of dental caries in low-income minority children: study protocol for a cluster randomized controlled trial. ( 30257696 )
2018
41
Digital behavior surveillance: Monitoring dental caries and toothache interests of Google users from developing countries. ( 30270556 )
2018
42
Decision tree analysis for factors associated with dental caries in school-aged children in Japan. ( 30284776 )
2018
43
Competence and Transformation of Oral Streptococcus sobrinus in Dental Caries. ( 30294143 )
2018
44
Dental Caries Experience, Dental Anomalies, and Morphometric Analysis of Canine among Monozygotic and Dizygotic Twins. ( 30294164 )
2018
45
Long-term scopolamine treatment and dental caries. ( 30298452 )
2018
46
Inequalities in dental caries in children within the UK: Have there been changes over time? ( 30298932 )
2018
47
Prevention and empathetic dentistry vital in managing child dental caries. ( 30310222 )
2018
48
Historical perspectives on advertising and the meme that personal oral hygiene prevents dental caries. ( 30318791 )
2018
49
Simplified Prediction Model for Accurate Assessment of Dental Caries Risk among Participants Aged 10-18 Years. ( 30333362 )
2018
50
Dental caries and developmental defects of enamel in individuals with chronic kidney disease: Systematic review and meta-analysis. ( 30338628 )
2018

Variations for Dental Caries

Expression for Dental Caries

Search GEO for disease gene expression data for Dental Caries.

Pathways for Dental Caries

Pathways related to Dental Caries according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.44 CST1 DMBT1 HTN1 LPO MUC7 PRH1

GO Terms for Dental Caries

Cellular components related to Dental Caries according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.86 CA6 CST1 DMBT1 FGF10 LPO LTF
2 extracellular region GO:0005576 9.5 AMELX CA6 CST1 DMBT1 DSPP ENAM
3 extracellular matrix GO:0031012 9.43 AMELX DMBT1 DSPP ENAM FGF10 TFIP11
4 other organism cell membrane GO:0044218 9.16 LTF MUC7

Biological processes related to Dental Caries according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.71 HTN1 LPO LTF STATH
2 cellular protein metabolic process GO:0044267 9.67 AMELX DMBT1 ENAM LTF
3 ossification GO:0001503 9.63 DSPP LTF STATH
4 defense response to Gram-negative bacterium GO:0050829 9.61 DMBT1 LTF LYZL2
5 odontogenesis of dentin-containing tooth GO:0042475 9.5 AMELX ENAM FGF10
6 killing of cells of other organism GO:0031640 9.33 HTN1 LTF MUC7
7 positive regulation of enamel mineralization GO:0070175 9.26 DSPP ENAM
8 detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 9.26 CA6 CST1 LPO TAS2R38
9 biomineral tissue development GO:0031214 9.17 AMELX DSPP ENAM HTN1 STATH TFIP11

Molecular functions related to Dental Caries according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydroxyapatite binding GO:0046848 8.96 AMELX STATH
2 structural constituent of tooth enamel GO:0030345 8.92 AMELX ENAM STATH TUFT1
3 protein binding GO:0005515 10.06 AMELX CA6 CD79A CST1 DMBT1 DSPP

Sources for Dental Caries

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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