MCID: DNT003
MIFTS: 30

Dental Pulp Calcification

Categories: Oral diseases

Aliases & Classifications for Dental Pulp Calcification

MalaCards integrated aliases for Dental Pulp Calcification:

Name: Dental Pulp Calcification 12 44 15 73
Pulpal Calcifications 12
Pulp Calcifications 12
Pulp Calcification 12
Dental Pulp Stone 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5608
ICD10 33 K04.2
MeSH 44 D003784
SNOMED-CT 68 57602001

Summaries for Dental Pulp Calcification

MalaCards based summary : Dental Pulp Calcification, also known as pulpal calcifications, is related to dentin dysplasia, type ii and root resorption. An important gene associated with Dental Pulp Calcification is ENAM (Enamelin), and among its related pathways/superpathways are Degradation of the extracellular matrix and Elastic fibre formation. Related phenotypes are behavior/neurological and growth/size/body region

Related Diseases for Dental Pulp Calcification

Graphical network of the top 20 diseases related to Dental Pulp Calcification:



Diseases related to Dental Pulp Calcification

Symptoms & Phenotypes for Dental Pulp Calcification

MGI Mouse Phenotypes related to Dental Pulp Calcification:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.98 BGN CTSC ENAM FBN1 FBN2 SPP1
2 growth/size/body region MP:0005378 9.97 BGN CTSC ENAM FBN1 FBN2 PDLIM7
3 homeostasis/metabolism MP:0005376 9.92 BGN CTSC ENAM FBN1 FBN2 PDLIM7
4 craniofacial MP:0005382 9.88 BGN ENAM FBN1 FBN2 SPP1 TGFBR2
5 immune system MP:0005387 9.8 BGN CHIT1 CTSC FBN1 PDLIM7 SPP1
6 muscle MP:0005369 9.55 BGN FBN1 FBN2 SPP1 TGFBR2
7 respiratory system MP:0005388 9.35 FBN1 FBN2 PDLIM7 SPP1 TGFBR2
8 skeleton MP:0005390 9.1 BGN ENAM FBN1 FBN2 SPP1 TGFBR2

Drugs & Therapeutics for Dental Pulp Calcification

Search Clinical Trials , NIH Clinical Center for Dental Pulp Calcification

Cochrane evidence based reviews: dental pulp calcification

Genetic Tests for Dental Pulp Calcification

Anatomical Context for Dental Pulp Calcification

Publications for Dental Pulp Calcification

Articles related to Dental Pulp Calcification:

# Title Authors Year
1
Can dental pulp calcification predict the risk of ischemic cardiovascular disease? ( 24910654 )
2013
2
Can dental pulp calcification serve as a diagnostic marker for carotid artery calcification in patients with renal diseases? ( 20026712 )
2009
3
Prevalence of pulpal calcifications in the primary dentition of Hispanic children. ( 10860084 )
1999
4
Radiographic pulpal calcifications: normal or abnormal--a paradox. ( 1895038 )
1991
5
Pulpal calcifications in patients with coronary atherosclerosis. ( 3481572 )
1987
6
Pulpal calcifications in primary teeth: a light microscope study. ( 3459852 )
1986
7
Unusual pulpal calcifications--a case report. ( 10621589 )
1976
8
Dental pulp calcification as a response to the methods of treatment. ( 4519735 )
1973

Variations for Dental Pulp Calcification

Expression for Dental Pulp Calcification

Search GEO for disease gene expression data for Dental Pulp Calcification.

Pathways for Dental Pulp Calcification

Pathways related to Dental Pulp Calcification according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.01 BGN DSPP FBN1 FBN2 SPP1
2
Show member pathways
11.23 FBN1 FBN2
3 11.09 SPP1 TGFBR2
4 11.01 BGN DSPP
5 10.82 SPP1 TGFBR2
6 10.2 FBN1 FBN2 TGFBR2

GO Terms for Dental Pulp Calcification

Cellular components related to Dental Pulp Calcification according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum lumen GO:0005788 9.56 CTSC ENAM FBN1 SPP1
2 extracellular region GO:0005576 9.56 BGN CHIT1 CTSC DSPP ENAM FBN1
3 collagen-containing extracellular matrix GO:0062023 9.46 BGN CTSC FBN1 FBN2
4 microfibril GO:0001527 9.32 FBN1 FBN2
5 extracellular matrix GO:0031012 9.02 BGN DSPP ENAM FBN1 FBN2

Biological processes related to Dental Pulp Calcification according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 post-translational protein modification GO:0043687 9.67 ENAM FBN1 SPP1
2 cellular protein metabolic process GO:0044267 9.61 ENAM FBN1 SPP1
3 response to organic substance GO:0010033 9.54 CTSC SPP1 TGFBR2
4 camera-type eye development GO:0043010 9.52 FBN1 FBN2
5 response to mechanical stimulus GO:0009612 9.51 DSPP TGFBR2
6 positive regulation of osteoblast differentiation GO:0045669 9.48 FBN2 PDLIM7
7 embryo implantation GO:0007566 9.46 SPP1 TGFBR2
8 response to steroid hormone GO:0048545 9.4 SPP1 TGFBR2
9 embryonic eye morphogenesis GO:0048048 9.32 FBN1 FBN2
10 positive regulation of enamel mineralization GO:0070175 9.26 DSPP ENAM
11 sequestering of TGFbeta in extracellular matrix GO:0035583 9.16 FBN1 FBN2
12 biomineral tissue development GO:0031214 9.13 DSPP ENAM SPP1
13 extracellular matrix organization GO:0030198 9.02 BGN DSPP FBN1 FBN2 SPP1

Molecular functions related to Dental Pulp Calcification according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix binding GO:0050840 9.26 BGN SPP1
2 glycosaminoglycan binding GO:0005539 9.16 BGN TGFBR2
3 extracellular matrix constituent conferring elasticity GO:0030023 8.96 FBN1 FBN2
4 extracellular matrix structural constituent GO:0005201 8.92 BGN DSPP FBN1 FBN2

Sources for Dental Pulp Calcification

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....