MCID: DNT003
MIFTS: 28

Dental Pulp Calcification

Categories: Oral diseases

Aliases & Classifications for Dental Pulp Calcification

MalaCards integrated aliases for Dental Pulp Calcification:

Name: Dental Pulp Calcification 12 44 15 73
Pulpal Calcifications 12
Pulp Calcifications 12
Pulp Calcification 12
Dental Pulp Stone 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5608
ICD10 33 K04.2
MeSH 44 D003784
SNOMED-CT 68 57602001

Summaries for Dental Pulp Calcification

MalaCards based summary : Dental Pulp Calcification, also known as pulpal calcifications, is related to dentin dysplasia, type ii and root resorption. An important gene associated with Dental Pulp Calcification is CHIT1 (Chitinase 1), and among its related pathways/superpathways are Degradation of the extracellular matrix and Elastic fibre formation. Related phenotypes are behavior/neurological and growth/size/body region

Related Diseases for Dental Pulp Calcification

Graphical network of the top 20 diseases related to Dental Pulp Calcification:



Diseases related to Dental Pulp Calcification

Symptoms & Phenotypes for Dental Pulp Calcification

MGI Mouse Phenotypes related to Dental Pulp Calcification:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.88 TGFBR2 BGN ENAM FBN1 FBN2 SPP1
2 growth/size/body region MP:0005378 9.87 BGN ENAM FBN1 FBN2 PDLIM7 SPP1
3 craniofacial MP:0005382 9.77 BGN ENAM FBN1 SPP1 TGFBR2
4 immune system MP:0005387 9.73 BGN CHIT1 FBN1 PDLIM7 SPP1 TGFBR2
5 muscle MP:0005369 9.55 BGN FBN1 FBN2 SPP1 TGFBR2
6 respiratory system MP:0005388 9.35 FBN1 FBN2 PDLIM7 SPP1 TGFBR2
7 skeleton MP:0005390 9.1 BGN ENAM FBN1 FBN2 SPP1 TGFBR2

Drugs & Therapeutics for Dental Pulp Calcification

Search Clinical Trials , NIH Clinical Center for Dental Pulp Calcification

Cochrane evidence based reviews: dental pulp calcification

Genetic Tests for Dental Pulp Calcification

Anatomical Context for Dental Pulp Calcification

Publications for Dental Pulp Calcification

Articles related to Dental Pulp Calcification:

# Title Authors Year
1
Can dental pulp calcification predict the risk of ischemic cardiovascular disease? ( 24910654 )
2013
2
Can dental pulp calcification serve as a diagnostic marker for carotid artery calcification in patients with renal diseases? ( 20026712 )
2009
3
Dental pulp calcification as a response to the methods of treatment. ( 4519735 )
1973

Variations for Dental Pulp Calcification

Expression for Dental Pulp Calcification

Search GEO for disease gene expression data for Dental Pulp Calcification.

Pathways for Dental Pulp Calcification

Pathways related to Dental Pulp Calcification according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.01 BGN DSPP FBN1 FBN2 SPP1
2
Show member pathways
11.23 FBN1 FBN2
3 11.09 SPP1 TGFBR2
4 11.01 BGN DSPP
5 10.82 SPP1 TGFBR2
6 10.2 FBN1 FBN2 TGFBR2

GO Terms for Dental Pulp Calcification

Cellular components related to Dental Pulp Calcification according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum lumen GO:0005788 9.43 ENAM FBN1 SPP1
2 extracellular matrix GO:0031012 9.33 BGN FBN1 FBN2
3 extracellular region GO:0005576 9.17 BGN CHIT1 DSPP ENAM FBN1 FBN2
4 microfibril GO:0001527 8.96 FBN1 FBN2

Biological processes related to Dental Pulp Calcification according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 post-translational protein modification GO:0043687 9.67 ENAM FBN1 SPP1
2 cellular protein metabolic process GO:0044267 9.58 ENAM FBN1 SPP1
3 camera-type eye development GO:0043010 9.51 FBN1 FBN2
4 extracellular matrix disassembly GO:0022617 9.5 FBN1 FBN2 SPP1
5 positive regulation of osteoblast differentiation GO:0045669 9.48 FBN2 PDLIM7
6 embryo implantation GO:0007566 9.46 SPP1 TGFBR2
7 response to steroid hormone GO:0048545 9.43 SPP1 TGFBR2
8 embryonic eye morphogenesis GO:0048048 9.37 FBN1 FBN2
9 regulation of cellular response to growth factor stimulus GO:0090287 9.26 FBN1 FBN2
10 sequestering of TGFbeta in extracellular matrix GO:0035583 9.16 FBN1 FBN2
11 biomineral tissue development GO:0031214 9.13 DSPP ENAM SPP1
12 extracellular matrix organization GO:0030198 9.02 BGN DSPP FBN1 FBN2 SPP1

Molecular functions related to Dental Pulp Calcification according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix binding GO:0050840 9.26 BGN SPP1
2 glycosaminoglycan binding GO:0005539 9.16 BGN TGFBR2
3 extracellular matrix constituent conferring elasticity GO:0030023 8.96 FBN1 FBN2
4 extracellular matrix structural constituent GO:0005201 8.92 BGN DSPP FBN1 FBN2

Sources for Dental Pulp Calcification

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....