MCID: DPN001
MIFTS: 29

Dependent Personality Disorder

Categories: Mental diseases

Aliases & Classifications for Dependent Personality Disorder

MalaCards integrated aliases for Dependent Personality Disorder:

Name: Dependent Personality Disorder 12 76 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10931
ICD10 33 F60.7
ICD9CM 35 301.6
MeSH 44 D003859
NCIt 50 C92637
SNOMED-CT 68 84466009
UMLS 73 C0011548

Summaries for Dependent Personality Disorder

Disease Ontology : 12 A personality disorder that is characterized by a pervasive psychological dependence on other people.

MalaCards based summary : Dependent Personality Disorder is related to personality disorder and separation anxiety disorder. An important gene associated with Dependent Personality Disorder is DRD4 (Dopamine Receptor D4), and among its related pathways/superpathways are superpathway of tryptophan utilization and Arginine and proline metabolism. Related phenotypes are behavior/neurological and homeostasis/metabolism

Wikipedia : 76 Dependent personality disorder (DPD), formerly known as asthenic personality disorder, is a personality... more...

Related Diseases for Dependent Personality Disorder

Diseases related to Dependent Personality Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
# Related Disease Score Top Affiliating Genes
1 personality disorder 31.0 MAOA DRD4
2 separation anxiety disorder 29.7 PIR DRD4
3 alcohol dependence 29.6 MAOB MAOA DRD4
4 disease of mental health 29.6 WASF2 MAOA DRD4
5 oppositional defiant disorder 10.2 MAOA DRD4
6 atypical depressive disorder 10.2 MAOB MAOA
7 kleptomania 10.1 MAOA CYP3A4
8 phobic disorder 10.1 PIR MAOA
9 brunner syndrome 10.1 MAOB MAOA
10 dysthymic disorder 10.1 PIR MAOA
11 dystonia 1, torsion, autosomal dominant 10.1 MAOB MAOA
12 pure autonomic failure 10.1 MAOB MAOA
13 agoraphobia 10.1 PIR MAOA
14 antisocial personality disorder 10.1 MAOB MAOA
15 conduct disorder 10.1 MAOA DRD4
16 pathological gambling 10.1 MAOB MAOA DRD4
17 schizoid personality disorder 10.1 PIR MME
18 mood disorder 10.1 MAOB MAOA DRD4
19 migraine with or without aura 1 10.1 MAOB MAOA DRD4
20 serotonin syndrome 10.0 MAOB MAOA CYP3A4
21 mental depression 10.0 WASF2 MAOA
22 exhibitionism 10.0 TNFSF11 MAOB MAOA
23 substance abuse 10.0 WASF2 MAOA DRD4
24 paraphilia disorder 10.0 TNFSF11 MAOB MAOA
25 hepatic encephalopathy 10.0 MAOB MAOA
26 attention deficit-hyperactivity disorder 10.0 MAOB MAOA DRD4
27 osteonecrosis 10.0 TNFSF11 CYP3A4
28 narcissistic personality disorder 10.0 WASF2 SMPD1 PIR
29 norrie disease 9.9 MAOB MAOA
30 orbital plasma cell granuloma 9.9 MME KNTC1
31 chronic orbital inflammation 9.9 MME KNTC1
32 alexithymia 9.9
33 panic disorder 9.9
34 histrionic personality disorder 9.8 PIR MME KNTC1
35 anxiety 9.7
36 social phobia 9.7
37 dementia 9.7
38 cocaine dependence 9.7

Comorbidity relations with Dependent Personality Disorder via Phenotypic Disease Network (PDN): (show all 20)


Acute Cystitis Anxiety
Avoidant Personality Disorder Borderline Personality Disorder
Dysthymic Disorder Esophagitis
Generalized Anxiety Disorder Histrionic Personality Disorder
Hypertension, Essential Hypochondriasis
Hypothyroidism Irritable Bowel Syndrome
Major Depressive Disorder Narcissistic Personality Disorder
Obsessive-Compulsive Disorder Obsessive-Compulsive Personality Disorder
Parkinson Disease, Late-Onset Personality Disorder
Schizophreniform Disorder Somatization Disorder

Graphical network of the top 20 diseases related to Dependent Personality Disorder:



Diseases related to Dependent Personality Disorder

Symptoms & Phenotypes for Dependent Personality Disorder

MGI Mouse Phenotypes related to Dependent Personality Disorder:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.5 ATG4C DRD4 KNTC1 MAOA MAOB SMPD1
2 homeostasis/metabolism MP:0005376 9.28 ATG4C DRD4 KNTC1 MAOA MAOB MME

Drugs & Therapeutics for Dependent Personality Disorder

Search Clinical Trials , NIH Clinical Center for Dependent Personality Disorder

Cochrane evidence based reviews: dependent personality disorder

Genetic Tests for Dependent Personality Disorder

Anatomical Context for Dependent Personality Disorder

Publications for Dependent Personality Disorder

Articles related to Dependent Personality Disorder:

(show all 25)
# Title Authors Year
1
A Big Five facet analysis of sub-clinical dependent personality disorder (Dutifulness). ( 30384281 )
2018
2
Dimensional clinical personality inventory-2: investigating key factors on the assessment of dependent personality disorder. ( 30514098 )
2018
3
Relationship between alexithymia and dependent personality disorder: a dimensional analysis. ( 25529260 )
2015
4
Is dependent personality disorder associated with mild cognitive impairment and dementia in Central Africa? A result from the EPIDEMCA programme. ( 25177857 )
2014
5
Dependent personality disorder: a critical review. ( 24185092 )
2013
6
Illuminating a neglected clinical issue: societal costs of interpersonal dependency and dependent personality disorder. ( 22623345 )
2012
7
The heritability of avoidant and dependent personality disorder assessed by personal interview and questionnaire. ( 22486635 )
2012
8
Alexithymia and dependent personality disorder. ( 22349651 )
2012
9
Dependent personality disorder and physical abuse. ( 20537714 )
2011
10
Reconceptualizing personality pathology in DSM-5: limitations in evidence for eliminating dependent personality disorder and other DSM-IV syndromes. ( 21466252 )
2011
11
Pre-treatment predictors and in-treatment factors associated with change in avoidant and dependent personality disorder traits among patients with social phobia. ( 19630068 )
2010
12
Rethinking dependent personality disorder: comparing different human relatedness in cultural contexts. ( 19996716 )
2009
13
Dependent personality disorder: comparing an expert generated and empirically derived five-factor model personality disorder count. ( 18258728 )
2008
14
Dependent personality disorder. Threatened by self-reliance, they take shelter in submission. ( 17443985 )
2007
15
The quality of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition dependent personality disorder prototype. ( 17067868 )
2006
16
The dimensionality of dependent personality disorder. ( 15615670 )
2004
17
Dependent personality disorder as a marker of "battered husband syndrome": a case exemplar. ( 14733462 )
2003
18
Comorbidity of dependent personality disorder and separation anxiety disorder in addictive disorders and in healthy subjects. ( 12239442 )
2002
19
D4 dopamine-receptor (DRD4) alleles and novelty seeking in substance-dependent, personality-disorder, and control subjects. ( 9345090 )
1997
20
The morbidity of DSM-III-R dependent personality disorder. ( 8551285 )
1996
21
Dependent personality disorder. Age, sex, and axis I comorbidity. ( 8551284 )
1996
22
Using the family history method to distinguish relatives of patients with dependent personality disorder from relatives of controls. ( 1798822 )
1991
23
Avoidant and dependent personality traits in relatives of patients with panic disorder, patients with dependent personality disorder, and normal controls. ( 1771212 )
1991
24
Comparisons of males and females with DSM-III dependent personality disorder. ( 2243898 )
1990
25
Dependent personality disorder associated with phobic avoidance in patients with panic disorder. ( 3826431 )
1987

Variations for Dependent Personality Disorder

Expression for Dependent Personality Disorder

Search GEO for disease gene expression data for Dependent Personality Disorder.

Pathways for Dependent Personality Disorder

GO Terms for Dependent Personality Disorder

Biological processes related to Dependent Personality Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.46 CYP3A4 MAOA MAOB PIR
2 neurotransmitter catabolic process GO:0042135 8.96 MAOA MAOB
3 dopamine catabolic process GO:0042420 8.62 MAOA MAOB

Molecular functions related to Dependent Personality Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.26 CYP3A4 MAOA MAOB PIR
2 primary amine oxidase activity GO:0008131 8.62 MAOA MAOB

Sources for Dependent Personality Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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