MCID: DPN001
MIFTS: 29

Dependent Personality Disorder

Categories: Mental diseases

Aliases & Classifications for Dependent Personality Disorder

MalaCards integrated aliases for Dependent Personality Disorder:

Name: Dependent Personality Disorder 12 76 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10931
ICD10 33 F60.7
ICD9CM 35 301.6
MeSH 44 D003859
NCIt 50 C92637
SNOMED-CT 68 192492003 84466009
UMLS 73 C0011548

Summaries for Dependent Personality Disorder

Disease Ontology : 12 A personality disorder that is characterized by a pervasive psychological dependence on other people.

MalaCards based summary : Dependent Personality Disorder is related to personality disorder and separation anxiety disorder. An important gene associated with Dependent Personality Disorder is DRD4 (Dopamine Receptor D4), and among its related pathways/superpathways are superpathway of tryptophan utilization and Histidine metabolism. Related phenotypes are behavior/neurological and homeostasis/metabolism

Wikipedia : 76 Dependent personality disorder (DPD), formerly known as asthenic personality disorder, is a personality... more...

Related Diseases for Dependent Personality Disorder

Diseases related to Dependent Personality Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 36)
# Related Disease Score Top Affiliating Genes
1 personality disorder 30.9 DRD4 MAOA MAOB
2 separation anxiety disorder 29.6 DRD4 LTBP3 RTN4
3 alcohol dependence 28.8 DRD4 MAOA MAOB
4 disease of mental health 27.3 DRD4 MAOA RTN4 WASF1 WASF2
5 atypical depressive disorder 10.6 MAOA MAOB
6 oppositional defiant disorder 10.5 DRD4 MAOA
7 kleptomania 10.5 CYP3A4 MAOA
8 dystonia 1, torsion, autosomal dominant 10.4 MAOA MAOB
9 brunner syndrome 10.4 MAOA MAOB
10 pathological gambling 10.3 DRD4 MAOA MAOB
11 pure autonomic failure 10.3 MAOA MAOB
12 early-onset schizophrenia 10.3 DRD4 MAOA
13 mood disorder 10.3 DRD4 MAOA MAOB
14 antisocial personality disorder 10.3 MAOA MAOB
15 migraine with or without aura 1 10.2 DRD4 MAOA MAOB
16 serotonin syndrome 10.2 CYP3A4 MAOA MAOB
17 exhibitionism 10.2 MAOA MAOB TNFSF11
18 occupational dermatitis 10.2 KNTC1 SMPD1
19 endogenous depression 10.1 LTBP3 MAOA
20 histrionic personality disorder 10.1 KNTC1 MME
21 orbital plasma cell granuloma 10.0 KNTC1 MME
22 narcissistic personality disorder 10.0 SMPD1 WASF2
23 chronic orbital inflammation 10.0 KNTC1 MME
24 alexithymia 9.8
25 substance abuse 9.7 DRD4 MAOA WASF2
26 aging 9.6
27 anxiety 9.6
28 social phobia 9.6
29 dementia 9.6
30 panic disorder 9.6
31 substance dependence 9.6
32 cocaine dependence 9.6
33 paraphilia disorder 9.6 MAOA MAOB RTN4 TNFSF11
34 tobacco addiction 9.5 MAOA WASF1 WASF2
35 avoidant personality disorder 9.0 MAOA MME WASF1 WASF2
36 mental depression 8.9 MAOA RTN4 WASF1 WASF2

Comorbidity relations with Dependent Personality Disorder via Phenotypic Disease Network (PDN): (show all 20)


Acute Cystitis Anxiety
Avoidant Personality Disorder Borderline Personality Disorder
Dysthymic Disorder Esophagitis
Generalized Anxiety Disorder Histrionic Personality Disorder
Hypertension, Essential Hypochondriasis
Hypothyroidism Irritable Bowel Syndrome
Major Depressive Disorder Narcissistic Personality Disorder
Obsessive-Compulsive Disorder Obsessive-Compulsive Personality Disorder
Parkinson Disease, Late-Onset Personality Disorder
Schizophreniform Disorder Somatization Disorder

Graphical network of the top 20 diseases related to Dependent Personality Disorder:



Diseases related to Dependent Personality Disorder

Symptoms & Phenotypes for Dependent Personality Disorder

MGI Mouse Phenotypes related to Dependent Personality Disorder:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.61 KNTC1 LTBP3 MAOA MAOB SMPD1 TNFSF11
2 homeostasis/metabolism MP:0005376 9.28 ATG4C DRD4 KNTC1 MAOA MAOB MME

Drugs & Therapeutics for Dependent Personality Disorder

Search Clinical Trials , NIH Clinical Center for Dependent Personality Disorder

Cochrane evidence based reviews: dependent personality disorder

Genetic Tests for Dependent Personality Disorder

Anatomical Context for Dependent Personality Disorder

Publications for Dependent Personality Disorder

Articles related to Dependent Personality Disorder:

(show all 22)
# Title Authors Year
1
Relationship between alexithymia and dependent personality disorder: a dimensional analysis. ( 25529260 )
2015
2
Is dependent personality disorder associated with mild cognitive impairment and dementia in Central Africa? A result from the EPIDEMCA programme. ( 25177857 )
2014
3
Dependent personality disorder: a critical review. ( 24185092 )
2013
4
Illuminating a neglected clinical issue: societal costs of interpersonal dependency and dependent personality disorder. ( 22623345 )
2012
5
The heritability of avoidant and dependent personality disorder assessed by personal interview and questionnaire. ( 22486635 )
2012
6
Alexithymia and dependent personality disorder. ( 22349651 )
2012
7
Dependent personality disorder and physical abuse. ( 20537714 )
2011
8
Reconceptualizing personality pathology in DSM-5: limitations in evidence for eliminating dependent personality disorder and other DSM-IV syndromes. ( 21466252 )
2011
9
Pre-treatment predictors and in-treatment factors associated with change in avoidant and dependent personality disorder traits among patients with social phobia. ( 19630068 )
2010
10
Rethinking dependent personality disorder: comparing different human relatedness in cultural contexts. ( 19996716 )
2009
11
Dependent personality disorder: comparing an expert generated and empirically derived five-factor model personality disorder count. ( 18258728 )
2008
12
Dependent personality disorder. Threatened by self-reliance, they take shelter in submission. ( 17443985 )
2007
13
The quality of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition dependent personality disorder prototype. ( 17067868 )
2006
14
The dimensionality of dependent personality disorder. ( 15615670 )
2004
15
Dependent personality disorder as a marker of "battered husband syndrome": a case exemplar. ( 14733462 )
2003
16
Comorbidity of dependent personality disorder and separation anxiety disorder in addictive disorders and in healthy subjects. ( 12239442 )
2002
17
D4 dopamine-receptor (DRD4) alleles and novelty seeking in substance-dependent, personality-disorder, and control subjects. ( 9345090 )
1997
18
The morbidity of DSM-III-R dependent personality disorder. ( 8551285 )
1996
19
Dependent personality disorder. Age, sex, and axis I comorbidity. ( 8551284 )
1996
20
Using the family history method to distinguish relatives of patients with dependent personality disorder from relatives of controls. ( 1798822 )
1991
21
Avoidant and dependent personality traits in relatives of patients with panic disorder, patients with dependent personality disorder, and normal controls. ( 1771212 )
1991
22
Comparisons of males and females with DSM-III dependent personality disorder. ( 2243898 )
1990

Variations for Dependent Personality Disorder

Expression for Dependent Personality Disorder

Search GEO for disease gene expression data for Dependent Personality Disorder.

Pathways for Dependent Personality Disorder

GO Terms for Dependent Personality Disorder

Cellular components related to Dependent Personality Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actin cytoskeleton GO:0015629 9.33 KNTC1 WASF1 WASF2
2 mitochondrial outer membrane GO:0005741 9.13 MAOA MAOB WASF1
3 SCAR complex GO:0031209 8.62 WASF1 WASF2

Biological processes related to Dependent Personality Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Rac protein signal transduction GO:0016601 9.26 WASF1 WASF2
2 neurotransmitter catabolic process GO:0042135 9.16 MAOA MAOB
3 dopamine catabolic process GO:0042420 8.96 MAOA MAOB
4 lamellipodium morphogenesis GO:0072673 8.62 WASF1 WASF2

Molecular functions related to Dependent Personality Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein kinase A binding GO:0051018 8.96 WASF1 WASF2
2 primary amine oxidase activity GO:0008131 8.62 MAOA MAOB

Sources for Dependent Personality Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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