MCID: DPR015
MIFTS: 22

Depersonalization/derealization Disorder

Categories: Mental diseases, Rare diseases

Aliases & Classifications for Depersonalization/derealization Disorder

MalaCards integrated aliases for Depersonalization/derealization Disorder:

Name: Depersonalization/derealization Disorder 53
Depersonalization Disorder 53 73

Classifications:



External Ids:

ICD10 33 F48.1
UMLS 73 C0683416

Summaries for Depersonalization/derealization Disorder

MalaCards based summary : Depersonalization/derealization Disorder, also known as depersonalization disorder, is related to depersonalization disorder and dissociative disorder. The drugs Fluoxetine and Cytochrome P-450 CYP2D6 Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include cortex, eye and pituitary.

Related Diseases for Depersonalization/derealization Disorder

Diseases related to Depersonalization/derealization Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 depersonalization disorder 11.9
2 dissociative disorder 11.4
3 anxiety 10.3
4 depression 10.3
5 schizophrenia 10.1
6 alexithymia 10.1
7 obsessive-compulsive disorder 9.9

Graphical network of the top 20 diseases related to Depersonalization/derealization Disorder:



Diseases related to Depersonalization/derealization Disorder

Symptoms & Phenotypes for Depersonalization/derealization Disorder

Drugs & Therapeutics for Depersonalization/derealization Disorder

Drugs for Depersonalization/derealization Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluoxetine Approved, Vet_approved Not Applicable 54910-89-3 3386
2 Cytochrome P-450 CYP2D6 Inhibitors Not Applicable
3 Psychotropic Drugs Not Applicable
4 Neurotransmitter Uptake Inhibitors Not Applicable
5 Cytochrome P-450 Enzyme Inhibitors Not Applicable
6 Antidepressive Agents Not Applicable
7 Neurotransmitter Agents Not Applicable
8 Serotonin Uptake Inhibitors Not Applicable
9 Serotonin Agents Not Applicable
10 Antidepressive Agents, Second-Generation Not Applicable
11
Serotonin Investigational, Nutraceutical Not Applicable 50-67-9 5202

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Treatment of Depersonalization Disorder With Transcranial Magnetic Stimulation (TMS) Completed NCT00529217 Phase 2
2 Treatment of Depersonalization Disorder With Repetitive Transcranial Magnetic Stimulation (rTMS) Withdrawn NCT02256085 Phase 2
3 Study of Fluoxetine in Patients With Depersonalization Disorder Completed NCT00004446 Not Applicable fluoxetine
4 Depersonalization Disorder: Therapeutic Effect of Neuronavigated Repetitive Transcranial Stimulation Recruiting NCT02476435 Not Applicable

Search NIH Clinical Center for Depersonalization/derealization Disorder

Genetic Tests for Depersonalization/derealization Disorder

Anatomical Context for Depersonalization/derealization Disorder

MalaCards organs/tissues related to Depersonalization/derealization Disorder:

41
Cortex, Eye, Pituitary, Skin, Brain, Testes, Prefrontal Cortex

Publications for Depersonalization/derealization Disorder

Articles related to Depersonalization/derealization Disorder:

(show top 50) (show all 82)
# Title Authors Year
1
Anomalous Self-Experiences: Markers of Schizophrenia Vulnerability or Symptoms of Depersonalization Disorder? A Phenomenological Investigation of Two Cases. ( 29730662 )
2018
2
White matter network alterations in patients with depersonalization/derealization disorder. ( 29877178 )
2018
3
White matter network alterations in patients with depersonalization/derealization disorder. ( 30125247 )
2018
4
Treatment of Depersonalization Disorder With Repetitive Transcranial Magnetic Stimulation. ( 28291040 )
2017
5
Treatment of a Patient With Depersonalization Disorder With Low Frequency Repetitive Transcranial Magnetic Stimulation of the Right Temporo-Parietal Junction in a Private Practice Setting. ( 28291041 )
2017
6
Ventrolateral prefrontal cortex repetitive transcranial magnetic stimulation in the treatment of depersonalization disorder: A consecutive case series. ( 27104926 )
2016
7
Emotional Experience and Awareness of Self: Functional MRI Studies of Depersonalization Disorder. ( 27313548 )
2016
8
Persistent Depersonalization/Derealization Disorder Induced by Synthetic Cannabinoids. ( 27477142 )
2016
9
Dissociable brain correlates for depression, anxiety, dissociation, and somatization in depersonalization-derealization disorder. ( 24059962 )
2016
10
Cognitive load and autonomic response patterns under negative priming demand in depersonalization-derealization disorder. ( 26791018 )
2016
11
Cardiac modulation of startle is altered in depersonalization-/derealization disorder: Evidence for impaired brainstem representation of baro-afferent neural traffic. ( 27078753 )
2016
12
Abnormal cardiovascular sympathetic and parasympathetic responses to physical and emotional stimuli in depersonalization disorder. ( 25859177 )
2015
13
Depersonalization/derealization disorder after exposure to mefloquine. ( 25619678 )
2015
14
Altered patterns of heartbeat-evoked potentials in depersonalization/derealization disorder: neurophysiological evidence for impaired cortical representation of bodily signals. ( 25984819 )
2015
15
STRESS AND TRAUMA: Psychotherapy and Pharmacotherapy for Depersonalization/Derealization Disorder. ( 25337444 )
2014
16
Aripiprazole in depersonalization disorder comorbid with major depression and obsessive-compulsive disorder: 3 cases. ( 24992087 )
2014
17
Grey matter alterations in patients with depersonalization disorder: a voxel-based morphometry study. ( 25285875 )
2014
18
Altered orientation of spatial attention in depersonalization disorder. ( 24594203 )
2014
19
Testing a neurobiological model of depersonalization disorder using repetitive transcranial magnetic stimulation. ( 24439959 )
2014
20
Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on Specific Symptom Clusters in Depersonalization Disorder (DPD). ( 23941986 )
2014
21
Striking discrepancy of anomalous body experiences with normal interoceptive accuracy in depersonalization-derealization disorder. ( 24587061 )
2014
22
How do you feel when you can't feel your body? Interoception, functional connectivity and emotional processing in depersonalization-derealization disorder. ( 24967634 )
2014
23
Interoceptive-reflective regions differentiate alexithymia traits in depersonalization disorder. ( 23932225 )
2013
24
Depersonalization disorder: disconnection of cognitive evaluation from autonomic responses to emotional stimuli. ( 24058547 )
2013
25
Preliminary physiological evidence for impaired emotion regulation in depersonalization disorder. ( 23507419 )
2013
26
Depicting depersonalization disorder. ( 23450287 )
2013
27
Implicit self-esteem in borderline personality and depersonalization disorder. ( 22493585 )
2012
28
Conditional reasoning in Asperger's syndrome and depersonalization disorder. ( 22922241 )
2012
29
Depersonalization disorder and anxiety: a special relationship? ( 22414660 )
2012
30
Multiple clinical traits predict clinical diagnosis of depersonalization disorder: implications for DSM-V. ( 22206878 )
2012
31
Who is the man in the mirror? Depersonalization disorder after obesity surgery. ( 21640666 )
2012
32
Psychophysiological investigations in depersonalization disorder and effects of electrodermal biofeedback. ( 22545565 )
2012
33
Cannabis-induced depersonalization disorder in adolescence. ( 22378193 )
2012
34
Depersonalization disorder may be related to glutamate receptor activation imbalance. ( 21742442 )
2011
35
The efficacy of lamotrigine in a resistant case of depersonalization disorder. ( 21769750 )
2011
36
Temporo-parietal junction stimulation in the treatment of depersonalization disorder. ( 20837362 )
2011
37
Lamotrigine in the immediate treatment of outpatients with depersonalization disorder without psychiatric comorbidity: randomized, double-blind, placebo-controlled study. ( 21192145 )
2011
38
Methylphenidate in depersonalization disorder: a case report. ( 21274825 )
2011
39
Skin conductance and memory fragmentation after exposure to an emotional film clip in depersonalization disorder. ( 20381160 )
2010
40
Depersonalization disorder. ( 20308898 )
2010
41
Is depersonalization disorder initiated by illicit drug use any different? A survey of 394 adults. ( 19538903 )
2009
42
Alexithymia, absorption, and cognitive failures in depersonalization disorder: a comparison to posttraumatic stress disorder and healthy volunteers. ( 19597356 )
2009
43
Reliability and validity of a Japanese version of the Cambridge depersonalization scale as a screening instrument for depersonalization disorder. ( 19566762 )
2009
44
ECEM (Eye Closure, Eye Movements): application to depersonalization disorder. ( 19862896 )
2009
45
Somatoform dissociation in depersonalization disorder. ( 19042782 )
2008
46
Depersonalization disorder: pharmacological approaches. ( 18088198 )
2008
47
Emotional memory and perception of emotional faces in patients suffering from depersonalization disorder. ( 17705944 )
2007
48
Temporal disintegration in depersonalization disorder. ( 17409052 )
2007
49
Cognitive functioning in depersonalization disorder. ( 18091191 )
2007
50
Lamotrigine as an add-on treatment for depersonalization disorder: a retrospective study of 32 cases. ( 16960469 )
2006

Variations for Depersonalization/derealization Disorder

Expression for Depersonalization/derealization Disorder

Search GEO for disease gene expression data for Depersonalization/derealization Disorder.

Pathways for Depersonalization/derealization Disorder

GO Terms for Depersonalization/derealization Disorder

Sources for Depersonalization/derealization Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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