Dermatitis

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Disease Ontology 11 DOID:2723 MeSH 43 D003872 NCIt 49 C2983

SNOMED-CT 68 238538009 ICD10 31 L27 L27.2 L27.8 L27.9 L30.8 L30.9 more UMLS 71 C0011603 C0013595 C3875321

MedlinePlus: ⁴¹ Eczema is a term for several different types of skin swelling. Eczema is also called dermatitis. Most types cause dry, itchy skin and rashes on the face, inside the elbows and behind the knees, and on the hands and feet. Scratching the skin can cause it to turn red, and to swell and itch even more. Eczema is not contagious. The cause of eczema is unknown. It is likely caused by both genetic and environmental factors. Eczema may get better or worse over time, but it is often a long-lasting disease. People who have it may also develop hay fever and asthma. The most common type of eczema is atopic dermatitis. It is most common in babies and children, but adults can have it too. As children who have atopic dermatitis grow older, this problem may get better or go away. But sometimes the skin may stay dry and get irritated easily. Treatments may include medicines, skin creams, light therapy, and good skin care. You can prevent some types of eczema by avoiding: Things that irritate your skin, such as certain soaps, fabrics, and lotions Stress Things you are allergic to, such as food, pollen, and animals NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

MalaCards based summary: Dermatitis, also known as eczema, is related to irritant dermatitis and dermatitis herpetiformis, and has symptoms including exanthema and pruritus. An important gene associated with Dermatitis is FLG (Filaggrin), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Salicylic acid and Titanium dioxide have been mentioned in the context of this disorder. Affiliated tissues include skin, breast and t cells, and related phenotypes are immune system and hematopoietic system

PubMed Health : ⁶³ Eczema: Eczema is a common, chronic, non-infectious skin condition. The main symptom of this inflammatory disease is a very itchy rash. It often affects children. In many cases eczema gets better as the years go by, and it may go away for a while or disappear altogether. Acute flare-ups can really affect quality of life. The itching can be especially bad, making it difficult to concentrate and sleep well. Some people are embarrassed if their rash is visible to others. By taking good care of your skin, using medication and avoiding irritants and other things that can trigger the eczema, it is usually possible to relieve the symptoms at least enough to live a fairly normal life. Eczema is sometimes also called "atopic eczema" or "atopic dermatitis."

Disease Ontology: ¹¹ A skin disease characterized by itchy, erythematous, vesicular, weeping and crusting patches of skin.

Wikipedia: ⁷⁵ Dermatitis is inflammation of the skin, typically characterized by itchiness, redness and a rash. In... more...

Eczema is a chronic condition. Treatment cannot cure it, but regular skin care and medication can help to keep the itching and rash at bay. The main treatment options are: Basic treatment : Lipid -replenishing and moisturizing products (emollients ) are generously applied to the skin at least twice a day to keep it from drying out. This can help relieve itching and protect the skin from germs and irritants. Special soaps, liquid cleansers and shampoos : Normal soaps and products like shampoo or shower gel contain various substances that can dry out your skin . Special cleansing products without these substances are available to get around this problem. But basic treatment with emollients can usually compensate for the loss of moisture caused by normal soaps. Steroid creams : Eczema flare -ups are usually treated with steroid creams because they can relieve the itching and inflammation . They are typically used only for acute symptoms. But they are sometimes used at regular intervals together with moisturizing skin care products (basic treatment ): for example, as a "weekend treatment" where a steroid cream is applied on one or two days a week. Pimecrolimus and tacrolimus : Pimecrolimus and tacrolimus are two other medicines that can be used to treat eczema . They are not approved for use in children under the age of two years, though. These two medicines are also applied to the skin in a cream or ointment, and can be used if steroid products are not an option. This might be the case if steroid treatment is not tolerated or is ineffective. Pimecrolimus and tacrolimus may also be an option for long-term treatment of sensitive skin in the face and neck area. They can also be used on one or two days per week only, as described above. Other eczema treatment options include wet wraps, UV radiation and medications that suppress certain immune responses. Tablets containing these medicines are used if other treatments don't work, or if the eczema is very severe or affects large areas of skin . Because they have an effect throughout the entire body, they may have more extensive side effects than topical treatments. Allergy medications (antihistamines ) are also commonly used to relieve itching . But research has now shown that they are not suitable for treating eczema , whether used as tablets or a cream. People often try out herbal products or dietary supplements, such as evening primrose oil , borage oil, vitamin B6, vitamin E and zinc . But research hasn't shown that these products are effective. Many other treatments such as laser therapies or hyposensitization have not yet been studied enough, so they are not recommended by medical associations.

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Alclometasone alclometasone dipropionate amcinonide Clobetasol Clobetasol Propionate cocoa butter Cod Liver Oil Colloidal oatmeal eucerin EUCERITE Glycerin GLYCERIN LIQUID GLYCERIN,ANHYDROUS GLYCERIN,DEHYDRATED Lactic acid

LACTIC ACID LIQUID LACTIC ACID,BUFFERED methdilazine Methdilazine hydrochloride OATMEAL 1 g in 1 g TOPICAL POWDER [Soothing Bath Treatment] Racemethionine retinol acetate retinyl palmitate Vitamin A VITAMIN A (AS ACETATE & BETA CAROTENE) VITAMIN A (AS PALMITATE & BETA CAROTENE) VITAMIN A (NATURAL) VITAMIN A PALMITATE (SOLUBILIZED) Zinc Oxide

Search GEO for disease gene expression data for Dermatitis.