Dermatitis, Atopic, 2 (ATOD2)

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Disease Ontology 12 DOID:0110098 OMIM 58 605803 MeSH 45 D003876

MedGen 43 C1853965 UMLS 74 C0011615 C1853965

UniProtKB/Swiss-Prot : ⁷⁶ Dermatitis atopic 2: Atopic dermatitis is a complex, inflammatory disease with multiple alleles at several loci thought to be involved in the pathogenesis. It commonly begins in infancy or early childhood and is characterized by a chronic relapsing form of skin inflammation, a disturbance of epidermal barrier function that culminates in dry skin, and IgE- mediated sensitization to food and environmental allergens. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee.

MalaCards based summary : Dermatitis, Atopic, 2, also known as atod2, is related to ichthyosis and ichthyosis vulgaris, and has symptoms including pruritus and exanthema. An important gene associated with Dermatitis, Atopic, 2 is FLG (Filaggrin), and among its related pathways/superpathways is Keratinization. Affiliated tissues include skin.

Disease Ontology : ¹² An atopic dermatitis conferred by variation in the FLG gene on chromosome 1q21.

Description from OMIM: 605803

Clinical features from OMIM:

605803

Search Clinical Trials , NIH Clinical Center for Dermatitis, Atopic, 2

betamethasone betamethasone acetate betamethasone benzoate betamethasone dipropionate betamethasone sodium phosphate betamethasone valerate betamethasone valerate pwdr doxepin doxepin hydrochloride fluocinolone

fluocinolone acetonide methdilazine methdilazine hydrochloride pimecrolimus tacrolimus trimeprazine trimeprazine tartrate triprolidine triprolidine hydrochloride zinc oxide

Search GEO for disease gene expression data for Dermatitis, Atopic, 2.