ATOD5
MCID: DRM057
MIFTS: 23

Dermatitis, Atopic, 5 (ATOD5)

Categories: Genetic diseases, Immune diseases, Neuronal diseases, Skin diseases

Aliases & Classifications for Dermatitis, Atopic, 5

MalaCards integrated aliases for Dermatitis, Atopic, 5:

Name: Dermatitis, Atopic, 5 56 71
Dermatitis, Atopic, Susceptibility to, 5 56 13
Atopic Dermatitis 5 12 15
Atod5 56 12
Dermatitis, Atopic 5 56

Classifications:



External Ids:

Disease Ontology 12 DOID:0110101
OMIM 56 605844
OMIM Phenotypic Series 56 PS603165
MedGen 41 C1853900
UMLS 71 C1853900

Summaries for Dermatitis, Atopic, 5

Disease Ontology : 12 An atopic dermatitis associated with variation in the region 13q12-q14.

MalaCards based summary : Dermatitis, Atopic, 5, also known as dermatitis, atopic, susceptibility to, 5, is related to dermatitis, atopic and ige responsiveness, atopic. An important gene associated with Dermatitis, Atopic, 5 is ATOD5 (Dermatitis, Atopic, 5), and among its related pathways/superpathways is Innate Lymphoid Cell Differentiation Pathways. The drugs Hydrocortisone and Hydrocortisone acetate have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and t cells.

More information from OMIM: 605844 PS603165

Related Diseases for Dermatitis, Atopic, 5

Diseases in the Dermatitis, Atopic family:

Dermatitis, Atopic, 2 Dermatitis, Atopic, 3
Dermatitis, Atopic, 4 Dermatitis, Atopic, 5
Dermatitis, Atopic, 6 Dermatitis, Atopic, 7
Dermatitis, Atopic, 8 Dermatitis, Atopic, 9

Diseases related to Dermatitis, Atopic, 5 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 dermatitis, atopic 31.1 PTGDR2 ATOD5
2 ige responsiveness, atopic 10.0

Symptoms & Phenotypes for Dermatitis, Atopic, 5

Clinical features from OMIM:

605844

Drugs & Therapeutics for Dermatitis, Atopic, 5

Drugs for Dermatitis, Atopic, 5 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
2
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
3 Hydrocortisone 17-butyrate 21-propionate Phase 4
4 Hydrocortisone hemisuccinate Phase 4
5 Dermatologic Agents Phase 4
6 Hydrocortisone-17-butyrate Phase 4
7 Anti-Inflammatory Agents Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Adherence to Topical Hydrocortisone 17-butyrate 0.1% (Locoid®) Using Different Vehicles in Adults With Atopic Dermatitis Completed NCT00693693 Phase 4 hydrocortisone 17-butyrate 0.1% Cream preparation;hydrocortisone 17-butyrate 0.1% Ointment preparation;hydrocortisone 17-butyrate 0.1% Lipocream preparation
2 A Multi-center, Open, Long-term Follow-up Study to Evaluate the Efficacy and Safety of FURESTEM-AD Inj. in Patients With Moderate to Severe Chronic Atopic Dermatitis: 5-year Results From the K0102 Extension Study Recruiting NCT03962387

Search NIH Clinical Center for Dermatitis, Atopic, 5

Genetic Tests for Dermatitis, Atopic, 5

Anatomical Context for Dermatitis, Atopic, 5

MalaCards organs/tissues related to Dermatitis, Atopic, 5:

40
Skin, Testes, T Cells

Publications for Dermatitis, Atopic, 5

Articles related to Dermatitis, Atopic, 5:

(show all 13)
# Title Authors PMID Year
1
Susceptibility loci for atopic dermatitis on chromosomes 3, 13, 15, 17 and 18 in a Swedish population. 56
12045207 2002
2
Association and linkage of atopic dermatitis with chromosome 13q12-14 and 5q31-33 markers. 56
11069631 2000
3
Effects of Merino Wool on Atopic Dermatitis Using Clinical, Quality of Life, and Physiological Outcome Measures. 61
30864970 2019
4
Epicutaneous allergen application preferentially boosts specific T cell responses in sensitized patients. 61
28912492 2017
5
The Trend of Change of Allergic Diseases over the Years: Three Repeated Surveys from 1994 to 2014. 61
28787739 2017
6
Urticarial dermatitis: clinical features, diagnostic evaluation, and etiologic associations in a series of 146 patients at Mayo Clinic (2006-2012). 61
24268310 2014
7
Characteristics and completeness of clinical trial registrations in psoriasis and atopic dermatitis. 61
17199575 2007
8
Japanese cedar pollen as an exacerbation factor in atopic dermatitis: results of atopy patch testing and histological examination. 61
16648919 2006
9
[Coexistent diseases in allergic asthmatic patients. A study of 100 cases]. 61
15491076 2004
10
Interleukin 4 and interferon-gamma expression of the dermal infiltrate in patients with erythroderma and mycosis fungoides. An immuno-histochemical study. 61
11028812 2000
11
Type-1 hypersensitivity reactions to Malassezia pachydermatis extracts in atopic dogs. 61
9659547 1998
12
Retinal detachment in patients with atopic dermatitis. 5-year retrospective survey. 61
7630624 1995
13
[Use of a new radioenzymatic test in urticaria and drug allergy]. 61
95431 1979

Variations for Dermatitis, Atopic, 5

Expression for Dermatitis, Atopic, 5

Search GEO for disease gene expression data for Dermatitis, Atopic, 5.

Pathways for Dermatitis, Atopic, 5

Pathways related to Dermatitis, Atopic, 5 according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.53 PTGDR2 ICOS

GO Terms for Dermatitis, Atopic, 5

Sources for Dermatitis, Atopic, 5

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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