ATOD8
MCID: DRM060
MIFTS: 24

Dermatitis, Atopic, 8 (ATOD8)

Categories: Genetic diseases, Immune diseases, Neuronal diseases, Skin diseases

Aliases & Classifications for Dermatitis, Atopic, 8

MalaCards integrated aliases for Dermatitis, Atopic, 8:

Name: Dermatitis, Atopic, 8 56 71
Atopic Dermatitis 8 12 15
Atod8 56 12
Dermatitis, Atopic, Susceptibility to, 8 56
Dermatitis, Atopic, Severity of 56
Dermatitis, Atopic 8 56

Classifications:



External Ids:

Disease Ontology 12 DOID:0110104
OMIM 56 613518
OMIM Phenotypic Series 56 PS603165
UMLS 71 C3150763

Summaries for Dermatitis, Atopic, 8

Disease Ontology : 12 An atopic dermatitis associated with variation in the region 4q22.1.

MalaCards based summary : Dermatitis, Atopic, 8, also known as atopic dermatitis 8, is related to dermatitis, atopic and aneruptive fever. An important gene associated with Dermatitis, Atopic, 8 is ATOD8 (Dermatitis, Atopic, 8), and among its related pathways/superpathways are Calcineurin-regulated NFAT-dependent transcription in lymphocytes and Th2 Differentiation. Affiliated tissues include skin and t cells.

More information from OMIM: 613518 PS603165

Related Diseases for Dermatitis, Atopic, 8

Graphical network of the top 20 diseases related to Dermatitis, Atopic, 8:



Diseases related to Dermatitis, Atopic, 8

Symptoms & Phenotypes for Dermatitis, Atopic, 8

Clinical features from OMIM:

613518

Drugs & Therapeutics for Dermatitis, Atopic, 8

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase IV Study Of The Impact Of Vorinostat On Cellular Signaling And Cytokine Production In Cutaneous T-Cell Lymphoma Patients With Pruritus Withdrawn NCT01801670

Search NIH Clinical Center for Dermatitis, Atopic, 8

Genetic Tests for Dermatitis, Atopic, 8

Anatomical Context for Dermatitis, Atopic, 8

MalaCards organs/tissues related to Dermatitis, Atopic, 8:

40
Skin, T Cells

Publications for Dermatitis, Atopic, 8

Articles related to Dermatitis, Atopic, 8:

# Title Authors PMID Year
1
Linkage of atopic dermatitis to chromosomes 4q22, 3p24 and 3q21. 56
19517137 2009
2
[Prevalence of allergic diseases in children with secondary renal tubular acidosis attending a tertiary care pediatric center]. 61
28658721 2017
3
Review of an established UK home phototherapy service 1998-2011: improving access to a cost-effective treatment for chronic skin disease. 61
24726005 2014
4
A distinct profile of serum levels of soluble intercellular adhesion molecule-1 and intercellular adhesion molecule-3 in mycosis fungoides and Sézary syndrome. 61
19615537 2009
5
Analysis of inpatient dermatologic referrals: insight into the educational needs of trainee doctors. 61
19002549 2009
6
Immunofluorescence of the skin in allergic diseases: an investigation of patients with contact dermatitis, allergic vasculitis and atopic dermatitis. 61
76388 1978

Variations for Dermatitis, Atopic, 8

Expression for Dermatitis, Atopic, 8

Search GEO for disease gene expression data for Dermatitis, Atopic, 8.

Pathways for Dermatitis, Atopic, 8

Pathways related to Dermatitis, Atopic, 8 according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.84 GATA3 FOXP3
2 10.29 GATA3 FOXP3

GO Terms for Dermatitis, Atopic, 8

Biological processes related to Dermatitis, Atopic, 8 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 T cell receptor signaling pathway GO:0050852 9.4 GATA3 FOXP3
2 negative regulation of inflammatory response GO:0050728 9.37 GATA3 FOXP3
3 chromatin remodeling GO:0006338 9.32 GATA3 FOXP3
4 response to virus GO:0009615 9.26 GATA3 FOXP3
5 negative regulation of interferon-gamma production GO:0032689 9.16 GATA3 FOXP3
6 positive regulation of interleukin-4 production GO:0032753 8.96 GATA3 FOXP3
7 negative regulation of interleukin-2 production GO:0032703 8.62 GATA3 FOXP3

Sources for Dermatitis, Atopic, 8

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....