Dermatographia disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Dermatographia

MalaCards integrated aliases for Dermatographia:

Name: Dermatographia ¹² ¹⁵ ¹⁷

Dermatographic Urticaria ¹² ⁷³ ³²

Dermographism ¹² ⁵⁴

Symptomatic Dermographism ⁷⁰

Classifications:

MalaCards categories:
Anatomical: Skin diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Diseases of the skin and subcutaneous tissue

Urticaria and erythema

Urticaria

Dermatographic urticaria

External Ids:

Disease Ontology ¹² DOID:743

ICD9CM ³⁴ 708.3

NCIt ⁵⁰ C111885

SNOMED-CT ⁶⁷ 201263000

ICD10 ³² L50.3

EFO ¹⁷ EFO_1000685

UMLS ⁷⁰ C0343065

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Summaries for Dermatographia

Disease Ontology : ¹² A physical urticaria induced by stroking of the skin.

MalaCards based summary : Dermatographia, also known as dermatographic urticaria, is related to physical urticaria and dermatitis, atopic, and has symptoms including integumentary system signs and symptoms and darier's sign. An important gene associated with Dermatographia is PRG2 (Proteoglycan 2, Pro Eosinophil Major Basic Protein). The drugs Omalizumab and Respiratory System Agents have been mentioned in the context of this disorder. Affiliated tissues include thyroid and skin.

Wikipedia : ⁷³ Dermatographic urticaria is a skin disorder and one of the most common types of urticaria, affecting... more...

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Related Diseases for Dermatographia

Diseases related to Dermatographia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 83)

#	Related Disease	Score	Top Affiliating Genes
1	physical urticaria	30.5	TPT1 SERPING1 FCER1A ETFA ENPP3 CD63
2	dermatitis, atopic	30.1	PRG2 IGHE CCR6
3	rhinitis	29.7	TPT1 PRG2 IGHE
4	hypereosinophilic syndrome	29.7	PRG2 IGHE FIP1L1
5	allergic rhinitis	29.6	TPT1 IGHE FCER1A
6	chronic urticaria	29.6	TPT1 IGHE FCER1A ENPP3 CD63
7	cholinergic urticaria	29.5	SERPING1 FCER1A ETFA ENPP3
8	chronic inducible urticaria	29.3	ZRANB3 FCER1A ENPP3 CD63
9	asthma	29.3	TPT1 PRG2 IGHE FCER1A CCR6
10	urticaria	29.1	TPT1 SERPING1 PRG2 IGHE FCER1A ENPP3
11	dermographism, familial	11.3
12	atopic keratoconjunctivitis	10.3	PRG2 IGHE
13	vernal conjunctivitis	10.2	IGHE CCR6
14	exercise-induced anaphylaxis	10.2	IGHE ENPP3
15	allergic urticaria	10.2	SERPING1 FCER1A
16	peach allergy	10.2	IGHE ENPP3
17	chronic conjunctivitis	10.2	IGHE CCR6
18	occupational asthma	10.2	TPT1 IGHE
19	eosinophilic gastroenteritis	10.2	PRG2 CCR6
20	wheat allergy	10.2	IGHE ENPP3
21	peanut allergy	10.2	IGHE CCR6
22	chlorhexidine allergy	10.1	ENPP3 CD63
23	crab allergy	10.1	ENPP3 CD63
24	loeffler endocarditis	10.1	PRG2 FIP1L1
25	beta-lactam allergy	10.1	IGHE ENPP3
26	oxirane allergy	10.1	ENPP3 CD63
27	diclofenac allergy	10.1	ENPP3 CD63
28	immunodeficiency with hyper-igm, type 1	10.1	IGHE CCR6
29	chronic spontaneous urticaria	10.1
30	dermatitis	10.1
31	mastocytosis	10.1
32	toxocariasis	10.1	IGHE FIP1L1
33	endomyocardial fibrosis	10.1	PRG2 FIP1L1
34	allergic disease	10.1	PRG2 IGHE CCR6
35	egg allergy	10.1	IGHE ENPP3 CCR6
36	ige responsiveness, atopic	10.0
37	exanthem	10.0
38	cold urticaria	10.0
39	mast-cell leukemia	10.0	FCER1A CD63
40	nail disorder, nonsyndromic congenital, 1	10.0	FIP1L1 CCR6
41	respiratory allergy	10.0	IGHE ENPP3 CCR6
42	scalp-ear-nipple syndrome	10.0	ENPP3 CD63
43	allergic bronchopulmonary aspergillosis	10.0	IGHE ENPP3
44	legume allergy	10.0	ENPP3 CD63 CCR6
45	fruit allergy	10.0	ENPP3 CD63 CCR6
46	mastocytosis, cutaneous	10.0
47	contact dermatitis	10.0
48	food allergy	9.9	TPT1 IGHE ENPP3
49	allergic conjunctivitis	9.9
50	conjunctivitis	9.9

Graphical network of the top 20 diseases related to Dermatographia:

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Symptoms & Phenotypes for Dermatographia

UMLS symptoms related to Dermatographia:

integumentary system signs and symptoms; darier's sign

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Drugs & Therapeutics for Dermatographia

Drugs for Dermatographia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Omalizumab

Approved, Investigational

Phase 2

242138-07-4

2

Respiratory System Agents

Phase 2

3

Anti-Asthmatic Agents

Phase 2

4

Immunoglobulins

Phase 2

5

Immunologic Factors

Phase 2

6

Anti-Allergic Agents

Phase 2

7

Antibodies

Phase 2

8

Antibodies, Monoclonal

Phase 2

9

Cholinergic Agents

Phase 1

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Double-blind, Placebo-controlled 12-week, Parallel-group Study With a 6 Weeks Follow up Period to Demonstrate Efficacy and Safety of Subcutaneous Omalizumab in Patients With Urticaria Factitia Refractory to Standard Treatment	Completed	NCT02169115	Phase 2	Omalizumab;Omalizumab;Placebo
2	An Open Label, Phase 1 Single Dose Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of CDX-0159 as Add on Therapy in Patients With Cold Contact Urticaria, Symptomatic Dermographism and Cholinergic Urticaria	Recruiting	NCT04548869	Phase 1	CDX-0159
3	Indocyanine Green Fluorescence Angiography in the Assessment of Deep Inferior Epigastric Perforator (DIEP) Flap Perfusion	Completed	NCT02759796
4	A 3D Tablet Sensor Approach to the Measurement of an Upper and Lower Limb Volume in the Monitoring of a Lymphedema	Not yet recruiting	NCT04821440

Search NIH Clinical Center for Dermatographia

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Genetic Tests for Dermatographia

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Anatomical Context for Dermatographia

MalaCards organs/tissues related to Dermatographia:

⁴⁰

Thyroid, Skin

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Publications for Dermatographia

Articles related to Dermatographia:

(show all 17)

#	Title	Authors	PMID	Year
1	Deep inferior epigastric perforator flap demonstrating the triple response of Lewis phenomenon - A case report and insights into aetiology. ⁶¹	Malik M...Cooper M	32158908	2020
2	Diagnostic utility of challenge procedures for physical urticaria/angioedema syndromes: a systematic review. ⁶¹	Cuervo-Pardo L...Lang DM	27585061	2016
3	Investigation of patient-specific characteristics associated with treatment outcomes for chronic urticaria. ⁶¹	Amin P...Bernstein JA	25680926	2015
4	Clinical and laboratory examinations in the subgroups of chronic urticaria. ⁶¹	Irinyi B...Szegedi A	17579280	2007
5	Behçets' disease: a case report. ⁶¹	Haile A	9558758	1997
6	Dermal and bronchial hyperreactivity in urticarial dermographism and urticaria factitia. ⁵⁴	Henz BM...Kunkel G	8781671	1996
7	Immunohistological comparison of granulated cell proteins in induced immediate urticarial dermographism and delayed pressure urticaria lesions. ⁵⁴	McEvoy MT...Leiferman KM	8547035	1995
8	[Clinical and histopathological observation and determination of serum IgE levels in patients with dermographism]. ⁵⁴	Wang Z	1303817	1992
9	Dermatographism in a horse. ⁶¹	Cornick JL...Brumbaugh GW	2912671	1989
10	Antihistamines in the treatment of urticarial disorders. ⁶¹	Shuster S	2903816	1988
11	[Dermatographic urticaria: evaluation of the therapeutic efficacy of drugs using a dermatographic tester]. ⁶¹	Lembo G...Patruno C	3129367	1987
12	Increased neurogenic inflammation in fibrositis syndrome. ⁶¹	Littlejohn GO...Helme RD	3480954	1987
13	Neurogenic flare responses in chronic rheumatic pain syndromes. ⁶¹	Helme RD...Weinstein C	3499268	1987
14	Papular dermatographia. ⁶¹	Burkhart CG	7451005	1980
15	[Dermatographia (Uriticaria factitia) in a cow. (Short clinical communication)]. ⁶¹	Stober M...Trautwein G	4928728	1971
16	Peculiarties in dermatology. Case reports. I. A case of dermatographia in an African patient. ⁶¹	Kingsley HJ	5683138	1968
17	A case of allergic conjunctivitis with dermatographia. ⁶¹	PAL D	14803111	1950

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Genes for Dermatographia

Genes related to Dermatographia (0 elite genes):

(show all 12)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	PRG2	Proteoglycan 2, Pro Eosinophil Major Basic Protein	Protein Coding	11.18	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁴	8547035
2	IGHE	Immunoglobulin Heavy Constant Epsilon	Protein Coding	7.13	Novoseek inferred ⁵⁴	1303817 8781671
3	CCR6	C-C Motif Chemokine Receptor 6	Protein Coding	6.93	DISEASES inferred ¹⁵ ¹⁵
4	FCER1A	Fc Fragment Of IgE Receptor Ia	Protein Coding	6.18	DISEASES inferred ¹⁵
5	SERPING1	Serpin Family G Member 1	Protein Coding	5.68	DISEASES inferred ¹⁵
6	CD63	CD63 Molecule	Protein Coding	5.59	DISEASES inferred ¹⁵
7	ENPP3	Ectonucleotide Pyrophosphatase/Phosphodiesterase 3	Protein Coding	5.47	DISEASES inferred ¹⁵
8	TPT1	Tumor Protein, Translationally-Controlled 1	Protein Coding	5.29	DISEASES inferred ¹⁵
9	FIP1L1	Factor Interacting With PAPOLA And CPSF1	Protein Coding	5.19	DISEASES inferred ¹⁵
10	ETFA	Electron Transfer Flavoprotein Subunit Alpha	Protein Coding	5.14	DISEASES inferred ¹⁵
11	CNOT11	CCR4-NOT Transcription Complex Subunit 11	Protein Coding	5.08	DISEASES inferred ¹⁵
12	ZRANB3	Zinc Finger RANBP2-Type Containing 3	Protein Coding	5.01	DISEASES inferred ¹⁵

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Variations for Dermatographia

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Expression for Dermatographia

Search GEO for disease gene expression data for Dermatographia.

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Pathways for Dermatographia

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GO Terms for Dermatographia

Cellular components related to Dermatographia according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	multivesicular body	GO:0005771	8.62	TPT1 CD63

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Sources for Dermatographia

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 20-May-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ Tocris

⁷⁰ UMLS

⁷¹ UMLS via Orphanet

⁷² UniProtKB/Swiss-Prot

⁷³ Wikipedia