MCID: DRM009
MIFTS: 35

Dermatomycosis

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Dermatomycosis

MalaCards integrated aliases for Dermatomycosis:

Name: Dermatomycosis 12 15
Dermatomycoses 44 70

Classifications:



External Ids:

Disease Ontology 12 DOID:1563
ICD9CM 34 111.9
MeSH 44 D003881
SNOMED-CT 67 47382004
UMLS 70 C0011630

Summaries for Dermatomycosis

Disease Ontology : 12 A cutaneous mycosis that results in fungal infection located in skin or of its appendages, has material basis in Ascomycota fungi other than the dermatophytes.

MalaCards based summary : Dermatomycosis, also known as dermatomycoses, is related to superficial mycosis and lobomycosis. An important gene associated with Dermatomycosis is POLR2B (RNA Polymerase II Subunit B). The drugs Ciclopirox and Clotrimazole have been mentioned in the context of this disorder. Affiliated tissues include skin and thymus.

Wikipedia : 73 A dermatomycosis is a skin disease caused by a fungus. This excludes... more...

Related Diseases for Dermatomycosis

Diseases related to Dermatomycosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 115)
# Related Disease Score Top Affiliating Genes
1 superficial mycosis 31.3 POLR2B ENSG00000202479 CLEC7A CD4
2 lobomycosis 31.2 SLA2 CR2 CD4
3 dermatophytosis 30.8 POLR2B CYP51A1 CLEC7A CD4
4 tinea capitis 30.6 POLR2B CLEC7A CD4
5 candidiasis 30.5 CYP51A1 CLEC7A CHIT1
6 tinea pedis 30.5 SLA2 CYP51A1 CLEC7A
7 fungal infectious disease 30.2 POLR2B CYP51A1 CLEC7A CD4
8 white piedra 30.1 POLR2B CLEC7A
9 mycetoma 30.0 TPT1 CHIT1
10 sporotrichosis 30.0 CLEC7A CD4
11 tinea nigra 30.0 POLR2B ENSG00000202479
12 histoplasmosis 29.9 CLEC7A CD4
13 cryptococcosis 29.9 CLEC7A CD4
14 nail disease 29.8 CLEC7A CD4
15 mucormycosis 29.8 CYP51A1 CLEC7A CD4
16 coccidioidomycosis 29.8 CYP51A1 CLEC7A CD4
17 oral candidiasis 29.7 CLEC7A CD4
18 eumycotic mycetoma 29.5 TUB TPT1 POLR2B IL37 ENSG00000202479 CYP51A1
19 tinea corporis 10.4
20 trichosporonosis 10.3 POLR2B CLEC7A
21 neuroaspergillosis 10.2 CYP51A1 CLEC7A
22 tinea cruris 10.2
23 pityriasis versicolor 10.2
24 blastomycosis 10.2 CLEC7A CD4
25 tinea unguium 10.2
26 rhinosporidiosis 10.2 CLEC7A CD4
27 parasitic ichthyosporea infectious disease 10.2 CLEC7A CD4
28 fungal meningitis 10.2 CYP51A1 CD4
29 actinomycosis 10.2 POLR2B CD4
30 drug allergy 10.2 TPT1 CD4
31 hyper ige recurrent infection syndrome 1 10.2 CLEC7A CD4
32 pneumocystosis 10.2 CLEC7A CD4
33 fusariosis 10.1 POLR2B CYP51A1 CLEC7A
34 noonan syndrome 4 10.1 POLR2B CD4
35 ostertagiasis 10.1 CR2 CLEC7A
36 uveoparotid fever 10.1 CHIT1 CD4
37 penicilliosis 10.1 POLR2B CLEC7A CD4
38 skin disease 10.1
39 subacute lymphocytic thyroiditis 10.1 CR2 CD4
40 subcutaneous mycosis 10.1 POLR2B CLEC7A CD4
41 granulomatous hepatitis 10.1 CR2 CD4
42 oral hairy leukoplakia 10.1 CR2 CD4
43 reticulum cell sarcoma 10.1 CR2 CD4
44 esophageal candidiasis 10.1 CYP51A1 CLEC7A CD4
45 vaginal disease 10.1 CLEC7A CD4
46 hepatic tuberculosis 10.1 CHIT1 CD4
47 primary systemic mycosis 10.1 CYP51A1 CLEC7A CD4
48 opportunistic mycosis 10.1 CYP51A1 CLEC7A CD4
49 noonan syndrome 8 10.1 TUB POLR2B
50 adult xanthogranuloma 10.1 CR2 CD4

Comorbidity relations with Dermatomycosis via Phenotypic Disease Network (PDN): (show all 22)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Alzheimer Disease
Chronic Kidney Disease Decubitus Ulcer
Deficiency Anemia Diabetic Polyneuropathy
Esophagitis Familial Atrial Fibrillation
Generalized Atherosclerosis Heart Disease
Hypertension, Essential Hypothyroidism
Iron Deficiency Anemia Mitral Valve Disease
Osteoporosis Paralytic Ileus
Peripheral Vascular Disease Protein-Energy Malnutrition
Respiratory Failure Schizophreniform Disorder

Graphical network of the top 20 diseases related to Dermatomycosis:



Diseases related to Dermatomycosis

Symptoms & Phenotypes for Dermatomycosis

Drugs & Therapeutics for Dermatomycosis

Drugs for Dermatomycosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ciclopirox Approved, Investigational Phase 4 29342-05-0 2749
2
Clotrimazole Approved, Vet_approved Phase 4 23593-75-1 2812
3
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
4 Anti-Infective Agents Phase 4
5 Antifungal Agents Phase 4
6
Itraconazole Approved, Investigational Phase 1 84625-61-6 55283
7 Cytochrome P-450 CYP3A Inhibitors Phase 1
8
Hydroxyitraconazole Phase 1 108222
9 Cytochrome P-450 Enzyme Inhibitors Phase 1
10 Hormone Antagonists Phase 1
11 Hormones Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study for the Assessment of Safety and Efficacy of Ciclopirox Olamine Cream in 3 Months to 10 Years Old Children With Dermatomycoses Terminated NCT01646580 Phase 4 ciclopirox
2 A Phase I Single-Center, Randomized, Open-label, Single Dose, Crossover Study in Korean Healthy Male Volunteers to Evaluate Pharmacokinetics of Lozanoc and Sporanox Completed NCT02493738 Phase 1 Lozanoc 50mg;Sporanox 100mg
3 The Efficacy of Pulsed Dye Laser in Dermatophytosis Completed NCT00351897 Phase 1
4 Observational Study of the Efficacy, Safety and Tolerance of Travogen Cream (Isoconazole) and Travocort Cream (Isoconazole, Diflurcortolone) in the Treatment of Patients With Local Skin Mycosis of Various Etiology and Localization Completed NCT00722189

Search NIH Clinical Center for Dermatomycosis

Inferred drug relations via UMLS 70 / NDF-RT 51 :


Povidone

Cochrane evidence based reviews: dermatomycoses

Genetic Tests for Dermatomycosis

Anatomical Context for Dermatomycosis

MalaCards organs/tissues related to Dermatomycosis:

40
Skin, Thymus

Publications for Dermatomycosis

Articles related to Dermatomycosis:

(show top 50) (show all 1236)
# Title Authors PMID Year
1
Virulence Factors and Antifungal Susceptibility in Candida Species Isolated from Dermatomycosis Patients. 61
33216273 2021
2
Genome Sequence of the Fungus Nannizziopsis barbatae, an Emerging Reptile Pathogen. 61
33414335 2021
3
Epidemiological Characterization of Dermatomycosis in Ethiopia. 61
33519223 2021
4
Complementary effect of mechanism of multidrug resistance in Trichophyton mentagrophytes isolated from human dermatophytoses of animal origin. 61
33448025 2021
5
Intrinsic resistance to terbinafine among human and animal isolates of Trichophyton mentagrophytes related to amino acid substitution in the squalene epoxidase. 61
32770418 2020
6
Histopathology, Molecular Identification and Antifungal Susceptibility Testing of Nannizziopsis arthrosporioides from a Captive Cuban Rock Iguana (Cyclura nubila). 61
32794052 2020
7
Cross-continental emergence of Nannizziopsis barbatae disease may threaten wild Australian lizards. 61
33262365 2020
8
Guidelines for the management of dermatomycosis (2019). 61
32978814 2020
9
Eosinophilic pustular folliculitis (EPF) in a patient with HIV infection. 61
33237446 2020
10
Deep fungal infections diagnosed by histology in Uganda: a 70-year retrospective study. 61
32242631 2020
11
Outbreak of Paranannizziopsis australasiensis Infection in Captive African Bush Vipers (Atheris squamigera). 61
33288159 2020
12
Epidemiology and Diagnostic Perspectives of Dermatophytoses. 61
33238603 2020
13
Polydopamine-modified interface improves the immobilization of natural bioactive-dye onto textile and enhances antifungal activity. 61
32838534 2020
14
Effectiveness of an encecalin standardized extract of Ageratina pichinchensis on the treatment of onychomycosis in patients with diabetes mellitus. 61
32086985 2020
15
Occurrence of various pathogenic and opportunistic fungi in skin diseases of domestic animals: a retrospective study. 61
32680509 2020
16
Endemic Chromoblastomycosis Caused Predominantly by Fonsecaea nubica, Madagascar1. 61
32441639 2020
17
Ex vivo nail infection as an effective preclinical method for screening of new topical antifungals. 61
32111505 2020
18
Unusual dermatomycoses caused by Nannizzia nana: the geophilic origin of human infections. 61
32232786 2020
19
Interdigital Tinea Nigra. 61
32391228 2020
20
8-Hydroxyquinoline-5-sulfonamides are promising antifungal candidates for the topical treatment of dermatomycosis. 61
31816165 2020
21
Spotting sporotrichosis skin infection: The first Australian paediatric case series. 61
31613031 2020
22
Discovery of a novel and selective fungicide that targets fungal cell wall to treat dermatomycoses: 1,3-bis(3,4-dichlorophenoxy)propan-2-aminium chloride. 61
31657052 2020
23
The potential for use of non-thermal plasma in microbiology and medicine. 61
32326713 2020
24
Prognostic factors influencing the treatment outcome of onychomycosis Candida. 61
31603597 2020
25
Dermatomycoses in the Israeli defense forces-Epidemiological and clinical aspects. 61
31599024 2020
26
Identification of Dermatophyte and Nondermatophyte Molds Isolated from Animal Lesions Suspected to Dermatomycoses. 61
32055538 2020
27
Auxotrophic mutations of Trichophyton rubrum created by in vitro synthesized Cas9 ribonucleoprotein. 61
31959181 2020
28
Epidemiological and clinical aspects of patients with Neoscytalidium spp. dermatomycoses in Switzerland. 61
31374133 2020
29
Ellagic Acid Inhibits Trichophyton rubrum Growth via Affecting Ergosterol Biosynthesis and Apoptotic Induction. 61
33193798 2020
30
A Two-Way Road: Antagonistic Interaction Between Dual-Species Biofilms Formed by Candida albicans/Candida parapsilosis and Trichophyton rubrum. 61
33013741 2020
31
Dermatomycosis in Cutaneous Tumors is a Predictor for Non-malignancy: A Cross-sectional Study. 61
31969235 2019
32
Sporotrichosis in the Highlands of Madagascar, 2013-20171. 61
31538565 2019
33
Epidemiology of dermatomycoses in southwest Poland, years 2011-2016. 61
31839778 2019
34
An unusual case of Lyme borreliosis: Can we miss it? 61
31579469 2019
35
ITS rDNA Gene Analysis Versus MALDI-TOF MS For Identification of Neoscytalidium dimidiatum Isolated from Onychomycosis and Dermatomycosis Cases in Medellin (Colombia). 61
31480602 2019
36
[Do the new molecular assays-microarray and realtime polymerase chain reaction-for dermatophyte detection keep what they promise?] 61
31263912 2019
37
[Dermatophytosis caused by rare anthropophilic and zoophilic agents]. 61
31139861 2019
38
Epidemiological survey of onychomycosis pathogens in Japan by real-time PCR. 61
30380094 2019
39
Occurrence of dermatophytoses in patients from the Sistema Único de Saúde. 61
31365657 2019
40
Comparing real-time PCR and Calcofluor-white with conventional methods for rapid detection of dermatophytes: Across-sectional study. 61
31022417 2019
41
Rapid tools to gain insights into the interaction dynamics of new 8-hydroxyquinolines with few fungal lines. 61
30450782 2019
42
Antifungal Activity of Griseofulvin Derivatives against Phytopathogenic Fungi in Vitro and in Vivo and Three-Dimensional Quantitative Structure-Activity Relationship Analysis. 61
31083998 2019
43
Occurrence of dermatophytoses in patients from the Sistema Único de Saúde. 61
33272535 2019
44
Tinea corporis infection manifestating as retinochoroiditis-an unusual presentation. 61
31131426 2019
45
Multiple abscesses in the lower extremities caused by Trichophyton rubrum. 61
30894136 2019
46
2016 Epidemiological Survey of Dermatomycoses in Japan. 61
31474694 2019
47
[Trichophyton mentagrophytes-from snow leopard to man : A molecular approach for uncovering the chain of infection]. 61
30120492 2018
48
A comparison of conventional rapid methods in diagnosis of superficial and cutaneous mycoses based on KOH, Chicago sky blue 6B and calcofluor white stains. 61
30873272 2018
49
Examen mycologique en dermatologie. 61
30143320 2018
50
The Oomycete Pythium oligandrum Can Suppress and Kill the Causative Agents of Dermatophytoses. 61
29967972 2018

Variations for Dermatomycosis

Expression for Dermatomycosis

Search GEO for disease gene expression data for Dermatomycosis.

Pathways for Dermatomycosis

GO Terms for Dermatomycosis

Biological processes related to Dermatomycosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of phagocytosis GO:0050766 9.26 TUB CLEC7A
2 immune response GO:0006955 9.26 IL37 CR2 CHIT1 CD4
3 positive regulation of interleukin-2 production GO:0032743 9.16 CLEC7A CD4
4 T cell activation GO:0042110 8.8 SLA2 CLEC7A CD4

Sources for Dermatomycosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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