MCID: DRM003
MIFTS: 26

Dermatosis Papulosa Nigra

Categories: Skin diseases
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Aliases & Classifications for Dermatosis Papulosa Nigra

MalaCards integrated aliases for Dermatosis Papulosa Nigra:

Name: Dermatosis Papulosa Nigra 57 11 43 14 16 71 75

Characteristics:


Inheritance:

? Autosomal dominant 57

Classifications:



External Ids:

Disease Ontology 11 DOID:4400
OMIM® 57 125600
MeSH 43 C562379
NCIt 49 C2984
SNOMED-CT 68 254669003
ICD10 31 L82
MedGen 40 C0011645
SNOMED-CT via HPO 69 199879009 95320005
UMLS 71 C0011645

Summaries for Dermatosis Papulosa Nigra

MalaCards based summary: Dermatosis Papulosa Nigra is related to keratosis, seborrheic and keratosis. An important gene associated with Dermatosis Papulosa Nigra is IMP3 (IMP U3 Small Nucleolar Ribonucleoprotein 3). The drugs Pharmaceutical Solutions and Racepinephrine have been mentioned in the context of this disorder. Affiliated tissues include skin, and related phenotype is abnormality of the skin.

Wikipedia: 75 Dermatosis papulosa nigra (DPN) is a condition of many small, benign skin lesions on the face, a... more...

More information from OMIM: 125600

Related Diseases for Dermatosis Papulosa Nigra

Diseases related to Dermatosis Papulosa Nigra via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 keratosis, seborrheic 30.6 FGFR3 DPH3
2 keratosis 10.6
3 yaws 10.6
4 dowling-degos disease 1 10.5
5 dilution, pigmentary 10.2
6 lentigines 10.2
7 rhabdomyosarcoma 2 10.2
8 deficiency anemia 10.2
9 iron deficiency anemia 10.2
10 colon adenocarcinoma 10.2
11 iron metabolism disease 10.2
12 papilloma 10.2
13 hypokalemia 10.2
14 acanthoma 9.9 FGFR3 DPH3
15 saethre-chotzen syndrome 9.7 SNX13 FGFR3
16 melanoacanthoma 9.7 IMP3 FGFR3 DPH3

Graphical network of the top 20 diseases related to Dermatosis Papulosa Nigra:



Diseases related to Dermatosis Papulosa Nigra

Symptoms & Phenotypes for Dermatosis Papulosa Nigra

Human phenotypes related to Dermatosis Papulosa Nigra:

30
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 abnormality of the skin 30 HP:0000951

Symptoms via clinical synopsis from OMIM®:

57 (Updated 24-Oct-2022)
Skin:
black to dark-brown cupoliform or flat facial papules
? variant of seborrheic keratoses

Misc:
occurrence predominantly in blacks

Clinical features from OMIM®:

125600 (Updated 24-Oct-2022)

Drugs & Therapeutics for Dermatosis Papulosa Nigra

Drugs for Dermatosis Papulosa Nigra (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Pharmaceutical Solutions Phase 2
2
Racepinephrine Approved, Vet_approved 51-43-4, 329-65-7 838 5816
3
Lidocaine Approved, Vet_approved 137-58-6 3676
4 Anesthetics
5 Epinephryl borate

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase 2 Open Label Study of A-101 Topical Solution in Subjects With Dermatosis Papulosa Nigra Completed NCT03224598 Phase 2 A-101 Topical Solution 40%
2 Efficacy of a 585 nm Pulsed Dye Laser (PDL) for the Treatment of Dermatosis Papulosa Nigra, and Compare it to Therapy With Curettage and Electrodesiccation. Completed NCT00710203

Search NIH Clinical Center for Dermatosis Papulosa Nigra

Cochrane evidence based reviews: dermatosis papulosa nigra

Genetic Tests for Dermatosis Papulosa Nigra

Anatomical Context for Dermatosis Papulosa Nigra

Organs/tissues related to Dermatosis Papulosa Nigra:

MalaCards : Skin

Publications for Dermatosis Papulosa Nigra

Articles related to Dermatosis Papulosa Nigra:

(show top 50) (show all 57)
# Title Authors PMID Year
1
A Systematic Review on the Treatment of Dermatosis Papulosa Nigra. 62
33852246 2021
2
Treatment of dermatosis papulosa nigra using a carbon dioxide laser. 62
31990432 2020
3
Elective Treatment of Dermatosis Papulosa Nigra: A Review of Treatment Modalities. 62
33017107 2020
4
Superimposed segmental dermatosis papulosa nigra. 62
31642076 2020
5
Dermatosis Papulosa Nigra: A Quality of Life Survey Study. 62
32308781 2020
6
[Clinical-pathological analysis of 71 cases of dermatosis papulosa nigra of Han Chinese people]. 62
31607018 2019
7
Pigmented transverse nasal band: A distinct presentation. 62
29808609 2019
8
Recent advances in managing and understanding seborrheic keratosis. 62
31508199 2019
9
First case of dermatosis papulosa nigra in a white child. 62
28846142 2017
10
A clinical, dermoscopic, and histopathological study of Dermatosis Papulosa Nigra (DPN) - An Indian perspective. 62
28485013 2017
11
Dermatosis papulosa nigra: a clinically and histopathologically distinct entity. 62
28916031 2017
12
Cutaneous problems in elderly diabetics: A population-based comparative cross-sectional survey. 62
27647359 2017
13
A Clinicopathological and Dermoscopic Correlation of Seborrheic Keratosis. 62
27904179 2016
14
Early-onset dermatosis papulosa nigra. 62
26639606 2016
15
Carbon dioxide laser ablation of dermatosis papulosa nigra: high satisfaction and few complications in patients with pigmented skin. 62
26868030 2016
16
Effectiveness of the Pulse Dye Laser Treatment in a Caucasian Women With Dermatosis Papulosa Nigra. 62
26120179 2015
17
Dermatosis Papulosa Nigra and 10,600-nm CO2 laser, a good choice. 62
24131098 2014
18
What's new in objective assessment and treatment of facial hyperpigmentation? 62
24679999 2014
19
Acquired hyperpigmentations. 62
24626644 2014
20
Dermatologic conditions in skin of color: part II. Disorders occurring predominately in skin of color. 62
23939568 2013
21
Spectrum of seborrheic keratoses in South Indians: a clinical and dermoscopic study. 62
21727696 2011
22
Laser eradication of pigmented lesions: a review. 62
21492309 2011
23
Postprocedural wound-healing efficacy following removal of dermatosis papulosa nigra lesions in an African American population: a comparison of a skin protectant ointment and a topical antibiotic. 62
21247663 2011
24
Treatment of dermatosis papulosa nigra in 10 patients: a comparison trial of electrodesiccation, pulsed dye laser, and curettage. 62
21040130 2010
25
Clinical features and treatment of dermatosis papulosa nigra in migrants to Italy. 62
21137605 2010
26
FGFR3 and PIK3CA mutations in stucco keratosis and dermatosis papulosa nigra. 62
19845664 2010
27
Dermatosis papulosa nigra treatment with fractional photothermolysis. 62
19796255 2009
28
Comparison of electrodesiccation and potassium-titanyl-phosphate laser for treatment of dermatosis papulosa nigra. 62
19469798 2009
29
Are all seborrheic keratoses benign? Review of the typical lesion and its variants. 62
18845088 2008
30
Treatment of dermatosis papulosa nigra with a 1064 nm Nd:YAG laser: report of two cases. 62
18569266 2008
31
Dermatosis papulosa nigra in Dakar, Senegal. 62
17919208 2007
32
Eruptive dermatosis papulosa nigra as a possible sign of internal malignancy. 62
17269973 2007
33
A randomized, double-blind comparison of two topical anesthetic formulations prior to electrodesiccation of dermatosis papulosa nigra. 62
16393591 2006
34
Study of the skin disease spectrum occurring in an Afro-Caribbean population. 62
12694494 2003
35
[Characteristics of genetically pigmented skins]. 62
15015846 2003
36
Dermatosis papulosa nigra in a young child. 62
8302739 1993
37
[Dermatosis papulosa nigra]. 62
3622869 1987
38
[A case of dermatosis papulosa nigra in a white man]. 62
6240957 1984
39
[Verrucous-form dermatosis papulosa nigra of the eyelid]. 62
6501785 1984
40
A surgical approach for dermatosis papulosa nigra. 62
6229500 1983
41
Dermatosis papulosa nigra. 62
6226495 1983
42
Dermatosis papulosa nigra and seborrheic keratoses: clinical aspects. 62
7386792 1980
43
[Dermatosis papulosa nigra]. 62
4802175 1973
44
[Castellani's dermatosis papulosa nigra]. 62
5558861 1971
45
Dermatosis papulosa nigra. 62
5662294 1968
46
[Dermatosis papulosa nigra]. 62
6045812 1967
47
[Dermatosis papulosa nigra (Castellani 1925)]. 62
4223695 1966
48
DERMATOSIS PAPULOSA NIGRA. 62
14122095 1964
49
[DERMATOSIS PAPULOSA NIGRA (CASTELLANI 1925)]. 62
14143405 1964
50
[CASTELLANI'S DERMATOSIS PAPULOSA NIGRA]. 62
14165081 1964

Variations for Dermatosis Papulosa Nigra

Expression for Dermatosis Papulosa Nigra

Search GEO for disease gene expression data for Dermatosis Papulosa Nigra.

Pathways for Dermatosis Papulosa Nigra

GO Terms for Dermatosis Papulosa Nigra

Sources for Dermatosis Papulosa Nigra

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 24-Oct-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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