MCID: DRM012
MIFTS: 22

Dermis Tumor

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Dermis Tumor

MalaCards integrated aliases for Dermis Tumor:

Name: Dermis Tumor 12 15
Neoplasm of Dermis 12
Tumor of Dermis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2438
NCIt 50 C4475
UMLS 73 C0346041

Summaries for Dermis Tumor

MalaCards based summary : Dermis Tumor, also known as neoplasm of dermis, is related to malignant dermis tumor and fibrous histiocytoma. An important gene associated with Dermis Tumor is HAVCR1 (Hepatitis A Virus Cellular Receptor 1), and among its related pathways/superpathways are Degradation of the extracellular matrix and Osteoblast Signaling. Affiliated tissues include skin, liver and bone.

Related Diseases for Dermis Tumor

Diseases in the Dermis Tumor family:

Malignant Dermis Tumor

Diseases related to Dermis Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 28)
# Related Disease Score Top Affiliating Genes
1 malignant dermis tumor 12.3
2 fibrous histiocytoma 10.1 CD163 SERPINA3
3 histiocytoma 10.1 CD163 SERPINA3
4 histiocytosis 10.1 CD163 SERPINA3
5 aleukemic leukemia cutis 10.1 HAVCR1 LYZ
6 liver sarcoma 10.1 LYZ PDGFB
7 cutaneous solitary mastocytoma 10.0 LYZ SERPINA3
8 central nervous system sarcoma 10.0 CD163 LYZ
9 xanthogranulomatous pyelonephritis 10.0 LYZ SERPINA3
10 congenital epulis 10.0 HAVCR1 LYZ
11 non-langerhans-cell histiocytosis 10.0 CD163 LYZ
12 histiocytic and dendritic cell cancer 10.0 CD163 LYZ
13 ring chromosome 4 10.0 COL1A1 PDGFB
14 bednar tumor 10.0 COL1A1 PDGFB
15 adult fibrosarcoma 10.0 COL1A1 PDGFB
16 xanthogranulomatous cholecystitis 10.0 LYZ SERPINA3
17 retinal hemangioblastoma 10.0 LYZ SERPINA3
18 malignant fibroxanthoma 10.0 LYZ SERPINA3
19 adult xanthogranuloma 9.9 CD163 HAVCR1 LYZ
20 malignant histiocytosis 9.9 LYZ PDGFB SERPINA3
21 bone ewing's sarcoma 9.9 B3GAT1 PDGFB
22 cutaneous fibrous histiocytoma 9.9 HAVCR1 MMP11 PDGFB SERPINA3
23 connective tissue cancer 9.9 COL1A1 PDGFB SERPINA3
24 skin sarcoma 9.9 CD163 COL1A1 PDGFB
25 urinary system disease 9.9 HAVCR1 LYZ
26 hypertelorism 9.8 COL1A1 SPECC1L
27 reticulohistiocytic granuloma 9.8 CD163 HAVCR1 LYZ SERPINA3
28 dermatofibrosarcoma protuberans 9.8 COL1A1 MMP11 PDGFB SERPINA3

Graphical network of the top 20 diseases related to Dermis Tumor:



Diseases related to Dermis Tumor

Symptoms & Phenotypes for Dermis Tumor

Drugs & Therapeutics for Dermis Tumor

Search Clinical Trials , NIH Clinical Center for Dermis Tumor

Genetic Tests for Dermis Tumor

Anatomical Context for Dermis Tumor

MalaCards organs/tissues related to Dermis Tumor:

41
Skin, Liver, Bone

Publications for Dermis Tumor

Variations for Dermis Tumor

Expression for Dermis Tumor

Search GEO for disease gene expression data for Dermis Tumor.

Pathways for Dermis Tumor

Pathways related to Dermis Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.79 COL1A1 MMP11 PDGFB
2 9.77 COL1A1 PDGFB

GO Terms for Dermis Tumor

Cellular components related to Dermis Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 azurophil granule lumen GO:0035578 9.26 LYZ SERPINA3
2 extracellular region GO:0005576 9.17 B3GAT1 CD163 COL1A1 LYZ MMP11 PDGFB
3 platelet alpha granule lumen GO:0031093 9.16 PDGFB SERPINA3
4 collagen-containing extracellular matrix GO:0062023 9.13 COL1A1 PDGFB SERPINA3

Biological processes related to Dermis Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.43 CD163 LYZ SERPINA3
2 collagen fibril organization GO:0030199 9.16 COL1A1 MMP11
3 acute-phase response GO:0006953 8.96 CD163 SERPINA3
4 extracellular matrix organization GO:0030198 8.8 COL1A1 MMP11 PDGFB

Molecular functions related to Dermis Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet-derived growth factor binding GO:0048407 8.62 COL1A1 PDGFB

Sources for Dermis Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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