MCID: DRM012
MIFTS: 22

Dermis Tumor

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Dermis Tumor

MalaCards integrated aliases for Dermis Tumor:

Name: Dermis Tumor 12 15
Neoplasm of Dermis 12
Tumor of Dermis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2438
NCIt 51 C4475
UMLS 74 C0346041

Summaries for Dermis Tumor

MalaCards based summary : Dermis Tumor, also known as neoplasm of dermis, is related to malignant dermis tumor and fibrous histiocytoma. An important gene associated with Dermis Tumor is SERPINA3 (Serpin Family A Member 3), and among its related pathways/superpathways are Degradation of the extracellular matrix and Dendritic Cells Developmental Lineage Pathway. Affiliated tissues include skin, kidney and bone.

Related Diseases for Dermis Tumor

Graphical network of the top 20 diseases related to Dermis Tumor:



Diseases related to Dermis Tumor

Symptoms & Phenotypes for Dermis Tumor

Drugs & Therapeutics for Dermis Tumor

Search Clinical Trials , NIH Clinical Center for Dermis Tumor

Genetic Tests for Dermis Tumor

Anatomical Context for Dermis Tumor

MalaCards organs/tissues related to Dermis Tumor:

42
Skin, Kidney, Bone

Publications for Dermis Tumor

Variations for Dermis Tumor

Expression for Dermis Tumor

Search GEO for disease gene expression data for Dermis Tumor.

Pathways for Dermis Tumor

Pathways related to Dermis Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.91 COL1A1 MMP11 PDGFB PECAM1
2 11.13 CD163 MME
3 10.76 COL1A1 PECAM1
4 9.77 COL1A1 PDGFB

GO Terms for Dermis Tumor

Cellular components related to Dermis Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet alpha granule lumen GO:0031093 9.16 PDGFB SERPINA3
2 collagen-containing extracellular matrix GO:0062023 9.13 COL1A1 PDGFB SERPINA3
3 extracellular region GO:0005576 9.1 B3GAT1 CD163 COL1A1 MMP11 PDGFB SERPINA3

Biological processes related to Dermis Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 collagen fibril organization GO:0030199 9.26 COL1A1 MMP11
2 acute-phase response GO:0006953 9.16 CD163 SERPINA3
3 platelet degranulation GO:0002576 9.13 PDGFB PECAM1 SERPINA3
4 extracellular matrix organization GO:0030198 8.92 COL1A1 MMP11 PDGFB PECAM1

Molecular functions related to Dermis Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet-derived growth factor binding GO:0048407 8.62 COL1A1 PDGFB

Sources for Dermis Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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