RBILD
MCID: DSQ001
MIFTS: 37

Desquamative Interstitial Pneumonia (RBILD)

Categories: Genetic diseases, Respiratory diseases

Aliases & Classifications for Desquamative Interstitial Pneumonia

MalaCards integrated aliases for Desquamative Interstitial Pneumonia:

Name: Desquamative Interstitial Pneumonia 12 55 15 73
Respiratory Bronchiolitis-Associated Interstitial Lung Disease 12
Respiratory Bronchiolitis Associated Interstitial Lung Disease 73
Interstitial Pneumonitis, Desquamative, Familial 44
Familial Desquamative Interstitial Pneumonitis 12
Rbild 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050158
ICD9CM 35 516.34 516.37
MeSH 44 C562470
NCIt 50 C35288
SNOMED-CT 68 8549006

Summaries for Desquamative Interstitial Pneumonia

Disease Ontology : 12 An idiopathic interstitial pneumonia that is characterized by the accumulation of bronchiolocentric alveolar macrophages in alveolar spaces and interstitial inflammation and involves mild bronchiolar fibrosis and chronic inflammation.

MalaCards based summary : Desquamative Interstitial Pneumonia, also known as respiratory bronchiolitis-associated interstitial lung disease, is related to pneumonia and pulmonary fibrosis, and has symptoms including respiratory distress, cyanosis and coughing. An important gene associated with Desquamative Interstitial Pneumonia is TNC (Tenascin C), and among its related pathways/superpathways are Lung fibrosis and Glycine, serine and threonine metabolism. The drugs Immunoglobulins and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include lung.

Wikipedia : 76 Desquamative interstitial pneumonia is a form of idiopathic interstitial pneumonia featuring elevated... more...

Related Diseases for Desquamative Interstitial Pneumonia

Diseases related to Desquamative Interstitial Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
# Related Disease Score Top Affiliating Genes
1 pneumonia 31.6 MUC5B SFTPC
2 pulmonary fibrosis 30.3 MUC5B SFTPC
3 lung disease 30.3 ABCA3 MUC5B SFTPC
4 interstitial lung disease 30.2 ABCA3 MUC5B SFTPC
5 diffuse pulmonary fibrosis 29.8 ABCA3 SFTPC
6 idiopathic interstitial pneumonia 29.8 MUC5B SFTPC
7 pulmonary fibrosis, idiopathic 29.7 ABCA3 MUC5B SFTPC
8 interstitial pneumonitis, desquamative, familial 12.0
9 bronchiolitis 10.5
10 adenocarcinoma 10.2
11 hepatitis c virus 10.2
12 hepatitis 10.2
13 pulmonary alveolar proteinosis 10.2
14 hepatitis c 10.2
15 histiocytosis 10.2
16 viral infectious disease 10.2
17 cryptogenic organizing pneumonia 10.0 MUC5B TNC
18 rheumatoid arthritis 10.0
19 scleroderma, familial progressive 10.0
20 sudden infant death syndrome 10.0
21 focal segmental glomerulosclerosis 1 10.0
22 langerhans cell histiocytosis 10.0
23 arthritis 10.0
24 focal segmental glomerulosclerosis 10.0
25 immunoglobulin alpha deficiency 10.0
26 pneumoconiosis 10.0
27 pneumothorax 10.0
28 larynx cancer 10.0
29 nonspecific interstitial pneumonia 10.0
30 rubella 10.0
31 pulmonary embolism 10.0
32 congenital rubella 10.0
33 labrador lung 10.0
34 neonatal respiratory failure 10.0 ABCA3 SFTPC
35 surfactant dysfunction 9.9 ABCA3 SFTPC
36 respiratory distress syndrome in premature infants 9.9 ABCA3 SFTPC
37 newborn respiratory distress syndrome 9.9 ABCA3 SFTPC
38 respiratory system disease 9.8 MUC5B SFTPC

Graphical network of the top 20 diseases related to Desquamative Interstitial Pneumonia:



Diseases related to Desquamative Interstitial Pneumonia

Symptoms & Phenotypes for Desquamative Interstitial Pneumonia

UMLS symptoms related to Desquamative Interstitial Pneumonia:


respiratory distress, cyanosis, coughing

Drugs & Therapeutics for Desquamative Interstitial Pneumonia

Drugs for Desquamative Interstitial Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Immunoglobulins
2 Antibodies

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT Completed NCT02036970 Phase 2 Bardoxolone methyl;Placebo
2 The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients With Interstitial Lung Disease Recruiting NCT02019641 Phase 2
3 Clinical Course of Interstitial Lung Diseases: European IPF Registry and Biobank Recruiting NCT02951416

Search NIH Clinical Center for Desquamative Interstitial Pneumonia

Cochrane evidence based reviews: interstitial pneumonitis, desquamative, familial

Genetic Tests for Desquamative Interstitial Pneumonia

Anatomical Context for Desquamative Interstitial Pneumonia

MalaCards organs/tissues related to Desquamative Interstitial Pneumonia:

41
Lung

Publications for Desquamative Interstitial Pneumonia

Articles related to Desquamative Interstitial Pneumonia:

(show top 50) (show all 132)
# Title Authors Year
1
Pulmonary Adenocarcinoma Mimicking Desquamative Interstitial Pneumonia: Report of 2 Cases With Genetic Analysis. ( 29720004 )
2018
2
Letter to the Editor: Desquamative interstitial pneumonia revisited half a century later. ( 29940655 )
2018
3
A Review of Smoking-Related Interstitial Fibrosis, Respiratory Bronchiolitis, and Desquamative Interstitial Pneumonia: Overlapping Histology and Confusing Terminology. ( 30281362 )
2018
4
Desquamative interstitial pneumonia complicated by diffuse alveolar haemorrhage. ( 29321935 )
2018
5
Smoking Relapse Causing an Acute Exacerbation of Desquamative Interstitial Pneumonia with Pleural Effusions and Mediastinal Adenopathies. ( 30046503 )
2018
6
Successful lung transplantation in an HIV seropositive patient with desquamative interstitial pneumonia: a case report. ( 30326889 )
2018
7
[Desquamative interstitial pneumonia: report of one case and review of literature]. ( 29050131 )
2017
8
Desquamative Interstitial Pneumonia Complicated with IgG4-related Lung Disease. ( 28626183 )
2017
9
Pulmonary Adenocarcinoma, Intra-alveolar Variant: A Rare Entity Mimicking Desquamative Interstitial Pneumonia. ( 28862049 )
2017
10
A case of mixed dust pneumoconiosis with desquamative interstitial pneumonia-like reaction in an aluminum welder. ( 28239542 )
2017
11
Respiratory bronchiolitis-associated interstitial lung disease secondary to electronic nicotine delivery system use confirmed with open lung biopsy. ( 28392919 )
2017
12
Transbronchial cryobiopsy in the diagnosis of desquamative interstitial pneumonia. ( 27134124 )
2016
13
Respiratory Bronchiolitis-Associated Interstitial Lung Disease in Childhood: New Sequela of Smoking. ( 26347438 )
2015
14
Near fatal desquamative interstitial pneumonia with bilateral recurrent tension pneumothorax. ( 26278697 )
2015
15
Desquamative interstitial pneumonia: a case report. ( 25518542 )
2014
16
Idiopathic desquamative interstitial pneumonia in a child: a case report. ( 24954625 )
2014
17
Lung tumors masquerading as desquamative interstitial pneumonia (DIP): report of 7 cases and review of the literature. ( 24805863 )
2014
18
Surgically proven desquamative interstitial pneumonia induced by waterproofing spray. ( 25224197 )
2014
19
Desquamative interstitial pneumonia in a child related to cigarette smoke. ( 23775787 )
2013
20
Desquamative interstitial pneumonia: an analytic review with an emphasis on aetiology. ( 23728865 )
2013
21
Desquamative interstitial pneumonia may progress to lung fibrosis as characterized radiologically. ( 22805187 )
2012
22
Desquamative interstitial pneumonia. ( 20854463 )
2011
23
Elevated serum levels of lysozyme in desquamative interstitial pneumonia. ( 20453406 )
2010
24
Desquamative interstitial pneumonia as the initial manifestation of systemic sclerosis. ( 20808169 )
2010
25
[A case of desquamative interstitial pneumonia associated with hepatitis C virus infection]. ( 19764512 )
2009
26
Desquamative interstitial pneumonia (DIP) in a patient with rheumatoid arthritis: is DIP associated with autoimmune disorders? ( 19443979 )
2009
27
Beneficial response to macrolide antibiotic in a patient with desquamative interstitial pneumonia refractory to corticosteroid therapy. ( 18628222 )
2008
28
Eosinophilia in bronchoalveolar lavage fluid and architectural destruction are features of desquamative interstitial pneumonia. ( 18184268 )
2008
29
Desquamative interstitial pneumonia with a remarkable increase in the number of BAL eosinophils. ( 18421198 )
2008
30
Sirolimus-associated desquamative interstitial pneumonia. ( 17164540 )
2007
31
Respiratory bronchiolitis-associated interstitial lung disease in a nonsmoker: radiologic and pathologic findings. ( 17449735 )
2007
32
Intractable desquamative interstitial pneumonia in a tattooed man. ( 17043377 )
2006
33
Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung disease. ( 15653981 )
2005
34
Desquamative interstitial pneumonia associated with concurrent cytomegalovirus and Aspergillus pneumonia in a renal transplant recipient. ( 15735246 )
2005
35
Respiratory bronchiolitis associated with interstitial lung disease and desquamative interstitial pneumonia. ( 15564017 )
2004
36
Desquamative interstitial pneumonia and hepatitis C virus infection: a rare association. ( 15455981 )
2004
37
Desquamative interstitial pneumonia, respiratory bronchiolitis and their relationship to smoking. ( 15330806 )
2004
38
Desquamative interstitial pneumonia masquerading as acute life-threatening pulmonary embolism. ( 15149053 )
2004
39
The overlap between respiratory bronchiolitis and desquamative interstitial pneumonia in pulmonary Langerhans cell histiocytosis: high-resolution CT, histologic, and functional correlations. ( 14555547 )
2003
40
A case of completely resolved pneumatocoeles in desquamative interstitial pneumonia. ( 14528887 )
2003
41
Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung disease. ( 16088687 )
2001
42
Idiopathic nonspecific interstitial pneumonia: prognostic significance of cellular and fibrosing patterns: survival comparison with usual interstitial pneumonia and desquamative interstitial pneumonia. ( 10632484 )
2000
43
Increasing dose of methylprednisolone pulse therapy treats desquamative interstitial pneumonia in a child. ( 10624777 )
1999
44
Respiratory bronchiolitis, respiratory bronchiolitis-associated interstitial lung disease, and desquamative interstitial pneumonia: different entities or part of the spectrum of the same disease process? ( 10584810 )
1999
45
Recurrence of desquamative interstitial pneumonia after lung transplantation. ( 9563761 )
1998
46
Fatal desquamative interstitial pneumonia associated with proven CMV infection in an 8-month-old boy. ( 9635938 )
1998
47
Differentiation of desquamative interstitial pneumonia (DIP) from pulmonary adenocarcinoma by immunocytochemistry. ( 9762545 )
1998
48
Desquamative interstitial pneumonia: an idiopathic interstitial pneumonia with a possibility of spontaneous regression. ( 9372323 )
1997
49
Recurrence of desquamative interstitial pneumonia after lung transplantation. ( 9412587 )
1997
50
Serial computed tomographic evaluation in desquamative interstitial pneumonia. ( 9196515 )
1997

Variations for Desquamative Interstitial Pneumonia

Expression for Desquamative Interstitial Pneumonia

Search GEO for disease gene expression data for Desquamative Interstitial Pneumonia.

Pathways for Desquamative Interstitial Pneumonia

GO Terms for Desquamative Interstitial Pneumonia

Cellular components related to Desquamative Interstitial Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 ABCA3 MUC5B NAPSA SFTPC TNC
2 multivesicular body lumen GO:0097486 8.96 NAPSA SFTPC
3 alveolar lamellar body GO:0097208 8.62 ABCA3 NAPSA

Biological processes related to Desquamative Interstitial Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 8.92 ABCA3 NAPSA SFTPC TNC

Sources for Desquamative Interstitial Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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