MCID: DSQ001
MIFTS: 38

Desquamative Interstitial Pneumonia

Categories: Respiratory diseases, Genetic diseases

Aliases & Classifications for Desquamative Interstitial Pneumonia

MalaCards integrated aliases for Desquamative Interstitial Pneumonia:

Name: Desquamative Interstitial Pneumonia 12 55 15 73
Respiratory Bronchiolitis-Associated Interstitial Lung Disease 12
Respiratory Bronchiolitis Associated Interstitial Lung Disease 73
Interstitial Pneumonitis, Desquamative, Familial 44
Familial Desquamative Interstitial Pneumonitis 12
Rbild 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050158
ICD9CM 35 516.34 516.37
MeSH 44 C562470
NCIt 50 C35288
SNOMED-CT 68 8549006

Summaries for Desquamative Interstitial Pneumonia

Disease Ontology : 12 An idiopathic interstitial pneumonia that is characterized by the accumulation of bronchiolocentric alveolar macrophages in alveolar spaces and interstitial inflammation and involves mild bronchiolar fibrosis and chronic inflammation.

MalaCards based summary : Desquamative Interstitial Pneumonia, also known as respiratory bronchiolitis-associated interstitial lung disease, is related to pneumonia and interstitial lung disease, and has symptoms including coughing, cyanosis and respiratory distress. An important gene associated with Desquamative Interstitial Pneumonia is TNC (Tenascin C), and among its related pathways/superpathways are Lung fibrosis and Glycine, serine and threonine metabolism. The drugs Antibodies and Immunoglobulins have been mentioned in the context of this disorder. Affiliated tissues include lung, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 76 Desquamative interstitial pneumonia is a form of idiopathic interstitial pneumonia featuring elevated... more...

Related Diseases for Desquamative Interstitial Pneumonia

Graphical network of the top 20 diseases related to Desquamative Interstitial Pneumonia:



Diseases related to Desquamative Interstitial Pneumonia

Symptoms & Phenotypes for Desquamative Interstitial Pneumonia

UMLS symptoms related to Desquamative Interstitial Pneumonia:


coughing, cyanosis, respiratory distress

GenomeRNAi Phenotypes related to Desquamative Interstitial Pneumonia according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-117 9.4 ASPH
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.4 ASPH
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.4 DLD
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-20 9.4 ASPH
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-203 9.4 DLD NAPSA
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-26 9.4 NAPSA
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-55 9.4 NAPSA
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-66 9.4 NAPSA
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-77 9.4 ASPH DLD NAPSA

Drugs & Therapeutics for Desquamative Interstitial Pneumonia

Drugs for Desquamative Interstitial Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antibodies
2 Immunoglobulins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT Completed NCT02036970 Phase 2 Bardoxolone methyl;Placebo
2 The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients With Interstitial Lung Disease Recruiting NCT02019641 Phase 2
3 Clinical Course of Interstitial Lung Diseases: European IPF Registry and Biobank Recruiting NCT02951416

Search NIH Clinical Center for Desquamative Interstitial Pneumonia

Cochrane evidence based reviews: interstitial pneumonitis, desquamative, familial

Genetic Tests for Desquamative Interstitial Pneumonia

Anatomical Context for Desquamative Interstitial Pneumonia

MalaCards organs/tissues related to Desquamative Interstitial Pneumonia:

41
Lung

Publications for Desquamative Interstitial Pneumonia

Articles related to Desquamative Interstitial Pneumonia:

(show top 50) (show all 126)
# Title Authors Year
1
Pulmonary Adenocarcinoma Mimicking Desquamative Interstitial Pneumonia: Report of 2 Cases With Genetic Analysis. ( 29720004 )
2018
2
Letter to the Editor: Desquamative interstitial pneumonia revisited half a century later. ( 29940655 )
2018
3
Desquamative interstitial pneumonia complicated by diffuse alveolar haemorrhage. ( 29321935 )
2018
4
[Desquamative interstitial pneumonia: report of one case and review of literature]. ( 29050131 )
2017
5
Desquamative Interstitial Pneumonia Complicated with IgG4-related Lung Disease. ( 28626183 )
2017
6
Pulmonary Adenocarcinoma, Intra-alveolar Variant: A Rare Entity Mimicking Desquamative Interstitial Pneumonia. ( 28862049 )
2017
7
A case of mixed dust pneumoconiosis with desquamative interstitial pneumonia-like reaction in an aluminum welder. ( 28239542 )
2017
8
Transbronchial cryobiopsy in the diagnosis of desquamative interstitial pneumonia. ( 27134124 )
2016
9
Near fatal desquamative interstitial pneumonia with bilateral recurrent tension pneumothorax. ( 26278697 )
2015
10
Desquamative interstitial pneumonia: a case report. ( 25518542 )
2014
11
Idiopathic desquamative interstitial pneumonia in a child: a case report. ( 24954625 )
2014
12
Lung tumors masquerading as desquamative interstitial pneumonia (DIP): report of 7 cases and review of the literature. ( 24805863 )
2014
13
Surgically proven desquamative interstitial pneumonia induced by waterproofing spray. ( 25224197 )
2014
14
Desquamative interstitial pneumonia in a child related to cigarette smoke. ( 23775787 )
2013
15
Desquamative interstitial pneumonia: an analytic review with an emphasis on aetiology. ( 23728865 )
2013
16
Desquamative interstitial pneumonia may progress to lung fibrosis as characterized radiologically. ( 22805187 )
2012
17
Desquamative interstitial pneumonia. ( 20854463 )
2011
18
Elevated serum levels of lysozyme in desquamative interstitial pneumonia. ( 20453406 )
2010
19
Desquamative interstitial pneumonia as the initial manifestation of systemic sclerosis. ( 20808169 )
2010
20
[A case of desquamative interstitial pneumonia associated with hepatitis C virus infection]. ( 19764512 )
2009
21
Desquamative interstitial pneumonia (DIP) in a patient with rheumatoid arthritis: is DIP associated with autoimmune disorders? ( 19443979 )
2009
22
Beneficial response to macrolide antibiotic in a patient with desquamative interstitial pneumonia refractory to corticosteroid therapy. ( 18628222 )
2008
23
Eosinophilia in bronchoalveolar lavage fluid and architectural destruction are features of desquamative interstitial pneumonia. ( 18184268 )
2008
24
Desquamative interstitial pneumonia with a remarkable increase in the number of BAL eosinophils. ( 18421198 )
2008
25
Sirolimus-associated desquamative interstitial pneumonia. ( 17164540 )
2007
26
Intractable desquamative interstitial pneumonia in a tattooed man. ( 17043377 )
2006
27
Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung disease. ( 15653981 )
2005
28
Desquamative interstitial pneumonia associated with concurrent cytomegalovirus and Aspergillus pneumonia in a renal transplant recipient. ( 15735246 )
2005
29
Respiratory bronchiolitis associated with interstitial lung disease and desquamative interstitial pneumonia. ( 15564017 )
2004
30
Desquamative interstitial pneumonia and hepatitis C virus infection: a rare association. ( 15455981 )
2004
31
Desquamative interstitial pneumonia, respiratory bronchiolitis and their relationship to smoking. ( 15330806 )
2004
32
Desquamative interstitial pneumonia masquerading as acute life-threatening pulmonary embolism. ( 15149053 )
2004
33
The overlap between respiratory bronchiolitis and desquamative interstitial pneumonia in pulmonary Langerhans cell histiocytosis: high-resolution CT, histologic, and functional correlations. ( 14555547 )
2003
34
A case of completely resolved pneumatocoeles in desquamative interstitial pneumonia. ( 14528887 )
2003
35
Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung disease. ( 16088687 )
2001
36
Idiopathic nonspecific interstitial pneumonia: prognostic significance of cellular and fibrosing patterns: survival comparison with usual interstitial pneumonia and desquamative interstitial pneumonia. ( 10632484 )
2000
37
Increasing dose of methylprednisolone pulse therapy treats desquamative interstitial pneumonia in a child. ( 10624777 )
1999
38
Respiratory bronchiolitis, respiratory bronchiolitis-associated interstitial lung disease, and desquamative interstitial pneumonia: different entities or part of the spectrum of the same disease process? ( 10584810 )
1999
39
Recurrence of desquamative interstitial pneumonia after lung transplantation. ( 9563761 )
1998
40
Fatal desquamative interstitial pneumonia associated with proven CMV infection in an 8-month-old boy. ( 9635938 )
1998
41
Differentiation of desquamative interstitial pneumonia (DIP) from pulmonary adenocarcinoma by immunocytochemistry. ( 9762545 )
1998
42
Desquamative interstitial pneumonia: an idiopathic interstitial pneumonia with a possibility of spontaneous regression. ( 9372323 )
1997
43
Recurrence of desquamative interstitial pneumonia after lung transplantation. ( 9412587 )
1997
44
Serial computed tomographic evaluation in desquamative interstitial pneumonia. ( 9196515 )
1997
45
Spontaneous remission of desquamative interstitial pneumonia. ( 9372337 )
1997
46
Disease progression in usual interstitial pneumonia compared with desquamative interstitial pneumonia. Assessment with serial CT. ( 8697837 )
1996
47
Desquamative interstitial pneumonia in sibs. ( 8585561 )
1995
48
Desquamative interstitial pneumonia: a case presentation. ( 8121260 )
1993
49
Desquamative interstitial pneumonia. ( 8300466 )
1993
50
Desquamative interstitial pneumonia: thin-section CT findings in 22 patients. ( 8497631 )
1993

Variations for Desquamative Interstitial Pneumonia

Expression for Desquamative Interstitial Pneumonia

Search GEO for disease gene expression data for Desquamative Interstitial Pneumonia.

Pathways for Desquamative Interstitial Pneumonia

GO Terms for Desquamative Interstitial Pneumonia

Cellular components related to Desquamative Interstitial Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.26 MUC5B NAPSA SFTPC TNC
2 multivesicular body lumen GO:0097486 8.62 NAPSA SFTPC

Biological processes related to Desquamative Interstitial Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 electron transport chain GO:0022900 9.16 ASPH DLD
2 cellular protein metabolic process GO:0044267 9.13 NAPSA SFTPC TNC
3 cellular nitrogen compound metabolic process GO:0034641 8.62 DLD GCSH

Molecular functions related to Desquamative Interstitial Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 electron transfer activity GO:0009055 8.62 ASPH DLD

Sources for Desquamative Interstitial Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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