MCID: DVL001
MIFTS: 34

Developmental Coordination Disorder

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Developmental Coordination Disorder

MalaCards integrated aliases for Developmental Coordination Disorder:

Name: Developmental Coordination Disorder 12 74 15 71
Motor Skills Disorders 44 71

Classifications:



External Ids:

Disease Ontology 12 DOID:9923
ICD9CM 34 315.4
MeSH 44 D019957
NCIt 50 C92561
SNOMED-CT 67 27544004
ICD10 32 F82
UMLS 71 C0011757 C0026613

Summaries for Developmental Coordination Disorder

Disease Ontology : 12 A specific developmental disorder that involves disordered motor skills where coordinated muscle movement is impaired.

MalaCards based summary : Developmental Coordination Disorder, also known as motor skills disorders, is related to dysgraphia and specific language impairment, and has symptoms including ataxia and clumsiness. An important gene associated with Developmental Coordination Disorder is PTPRN2 (Protein Tyrosine Phosphatase Receptor Type N2), and among its related pathways/superpathways is FOXA2 and FOXA3 transcription factor networks. The drugs Methylphenidate and Uric acid have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and endothelial.

Wikipedia : 74 Developmental coordination disorder (DCD), also known as developmental motor coordination disorder,... more...

Related Diseases for Developmental Coordination Disorder

Diseases related to Developmental Coordination Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 70)
# Related Disease Score Top Affiliating Genes
1 dysgraphia 31.8 CEBPD ABCB10
2 specific language impairment 30.1 NOP9 CLASRP CEBPD ATP2C2
3 reading disorder 29.7 CEBPD ATP2C2
4 developmental dyspraxia 11.6
5 attention deficit-hyperactivity disorder 10.8
6 autism spectrum disorder 10.6
7 agnosia 10.6
8 pre-descemet corneal dystrophy 10.6
9 autism 10.6
10 agenesis of corpus callosum, cardiac, ocular, and genital syndrome 10.5
11 cerebral palsy 10.5
12 dyslexia 10.5
13 learning disability 10.5
14 hand skill, relative 10.3
15 dysphasia, familial developmental 10.3
16 ataxia and polyneuropathy, adult-onset 10.3
17 anxiety 10.3
18 hypermobile ehlers-danlos syndrome 10.3
19 hypotonia 10.2
20 exudative vitreoretinopathy 1 10.2
21 alacrima, achalasia, and mental retardation syndrome 10.2
22 apraxia 10.2
23 disease of mental health 10.2
24 writing disorder 10.1 CEBPD ABCB10
25 expressive language disorder 10.1 CEBPD ATP2C2
26 niemann-pick disease, type c1 10.1
27 oculocerebral syndrome with hypopigmentation 10.1
28 congenital hemidysplasia with ichthyosiform erythroderma and limb defects 10.1
29 global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies 10.1
30 b-lymphoblastic leukemia/lymphoma 10.1
31 ehlers-danlos syndrome 10.1
32 hypermobility syndrome 10.1
33 niemann-pick disease 10.1
34 vascular disease 10.1
35 epilepsy 10.1
36 movement disease 10.1
37 depression 10.1
38 spasticity 10.1
39 specific learning disability 10.1
40 atrial septal defect 1 10.0 RBFOX1 CEBPD
41 articulation disorder 10.0 CEBPD ATP2C2
42 ehlers-danlos syndrome, hypermobility type 9.9
43 greig cephalopolysyndactyly syndrome 9.9
44 schizophrenia 9.9
45 digeorge syndrome 9.9
46 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.9
47 body mass index quantitative trait locus 1 9.9
48 actn3 deficiency 9.9
49 speech and communication disorders 9.9
50 restless legs syndrome 9.9

Graphical network of the top 20 diseases related to Developmental Coordination Disorder:



Diseases related to Developmental Coordination Disorder

Symptoms & Phenotypes for Developmental Coordination Disorder

UMLS symptoms related to Developmental Coordination Disorder:


ataxia, clumsiness

Drugs & Therapeutics for Developmental Coordination Disorder

Drugs for Developmental Coordination Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methylphenidate Approved, Investigational 113-45-1 4158
2
Uric acid Investigational 69-93-2 1175
3 Pharmaceutical Solutions
4 Insulin, Globin Zinc
5 insulin

Interventional clinical trials:

(show all 44)
# Name Status NCT ID Phase Drugs
1 Effects of Delayed Cord Clamping in Very Low Birth Weight (VLBW) Infants Completed NCT00840983 Phase 1
2 A Randomised Controlled Trial of the Effectiveness of Adapted Taekwondo Training on Skeletal Development and Motor Proficiency in Pre-pubertal Children With Developmental Coordination Disorder Unknown status NCT02635711
3 The Effect of Timocco's Virtual Reality Environment on the Motor Functioning and Participation Abilities Among Children With DCD Unknown status NCT02504385
4 Improving Mental Attention, Timing of Muscle Activation and Reactive Balance Control in Children With Developmental Coordination Disorder: A Randomized Controlled Trial Unknown status NCT02397161
5 Enhancing Neuromuscular Performance and Central Nervous System Plasticity Through Functional Movement-power Training to Improve Balance Strategies in Children With Developmental Coordination Disorder: A Randomised Controlled Trial Unknown status NCT02393404
6 Brain Plasticity and Motor Skill Competence Development in Young People With Development Coordination Disorder Unknown status NCT03150784
7 The Effects of K-Tape on Walking Pattern, Muscle Activity, and Motor Performance in Children With and Without Developmental Coordination Disorder: a Randomized Controlled Trial Unknown status NCT02945124
8 Transcranial Noninvasive Brain Stimulation With Random Noise for Children With Congenital or Acquired Brain Injury Unknown status NCT02656433
9 Characterization of Executive Functions and Patterns of Eye Movements in Children With Developmental Disabilities Unknown status NCT00716235
10 Developmental Coordination Disorder: Integrating Brain Imaging and Rehabilitation to Improve Outcomes Completed NCT02597751
11 Effects of the Cognitive Orientation to Daily Occupational Performance Approach on Activity and Participation of Brazilian Children With Developmental Coordination Disorder Completed NCT02893852
12 Effects of Trampoline Exercises Children With Developmental Coordination Disorder Completed NCT04694352
13 Transcranial Direct Current Stimulation (tDCS): A Therapeutic Intervention for Motor Impairments in Children With Developmental Coordination Disorder (DCD). Completed NCT03453983
14 The Effectiveness of Fitball Program Versus Task-oriented Motor Program on Improving Postural Control and Motor Proficiency in Children With Developmental Coordination Disorder Completed NCT01207544
15 A Randomized Feasibility Trial Evaluating a Teleintervention for Families of Children With Developmental Coordination Disorder (DCD) Completed NCT03141333
16 A Randomised Controlled Trial of a Group-based, Gaze Training Intervention for Children With Developmental Coordination Disorder Completed NCT02904980
17 Efficacy of the Cognitive Orientation to Daily Occupational Performance (CO-OP) Approach With Brazilian Children With Developmental Coordination Disorder Completed NCT03112746
18 Reliability and Validity of a Computerized Tool to Assess Proprioception Among Children With Coordination Disorders Completed NCT03285776
19 Functional MRI Study of the Involvement of Cortico-cerebellar and Cortico-striatal Networks in Children With a Developmental Coordination Disorder (DCD) and/or Developmental Dyslexia (DD) Completed NCT02393729
20 Profile of Newborn Undergoing Early Stimulation in a Neonatal Intensive Care Unit. Completed NCT01660178
21 Evolution of Maternal Weight During Pregnancy and Influence on the Endothelial Function in Her Offspring Completed NCT02992106
22 Hippotherapy to Improve Balance Deficits in a Cohort of Children With Movement Disorders: A Pilot Study Completed NCT01313325
23 Characteristic of Play: Comparison Between Children With Development Coordination Disorder ( DCD) and Children With Typical Development Completed NCT01130038
24 The Efficacy of Neurophysiologically Based Occupational Therapy Intervention in the Neonatal Intensive Care Unit: An Exploratory Study Completed NCT00766051
25 Objective Examination and Rehabilitation Treatment of Patients With BPPV Completed NCT04367194
26 The Effects of Exercise Therapy on the Co-Morbidity of Attention Deficit and Hyperactivity Disorder (ADHD) and Developmental Co-Ordination Disorder. (DCD) Completed NCT03595826 Neurostimulant pharmaceutical drugs
27 Neurobehavioural Development of Infants Born <30 Weeks Gestational Age and Their Parents Psychological Wellbeing Between Birth and Five Years of Age Completed NCT03172104
28 Changes in Motor Skill Proficiency After Equine-Assisted Activities and Brain-Building Tasks in Youth With Neurodevelopmental Disorders Completed NCT04158960
29 The Effect of Cognitive and Motor Training on Executive Functions, Motor Skills, and Saccadic Eye Movements System in Pediatric Posterior Fossa Tumor Survivors Completed NCT03951246
30 The Motor Neurological Soft Signs (MNSS) in Persons With Schizophrenia Completed NCT04495998
31 Motor Proficiency in School Age ADHD: Contribution of Different Comorbidities Completed NCT04494230
32 Integrating Brain Imaging and Rehabilitation to Improve Outcomes for Children With Co-occurring DCD & ASD Recruiting NCT04119492
33 tDCS and Motor Learning in Children With DCD Recruiting NCT04490187
34 Developmental Coordination Disorder in Preterm Children: Examining Brain Changes With CO-OP Intervention Recruiting NCT04483401
35 Tai Chi-muscle Power Training for Primary School Children With Developmental Coordination Disorder: A Randomized Controlled Trial Recruiting NCT03598478
36 An Explorative Retrospective Video-analysis of the Motor Development of Children With Developmental Coordination Disorder Before the Age of Two Recruiting NCT04126395
37 The Development of Children With Developmental Coordination Disorder (DCD) Before the Age of Six: a Follow-up Study Recruiting NCT03690843
38 Effect of Transcranial Direct Current Stimulation (tDCS) on Postural Control of Children With Developmental Coordination Disorder: a Double-blind Randomized Controlled Trial Recruiting NCT03892083
39 Sensitivity of the Search for a Heterophory-Vertical-Labile (HV-Labile) for Ambulatory Screening for Specific Learning Disabilities (SLD) or Developmental Coordination Disorder (DCD). Recruiting NCT04122820
40 Correspondence Between Motor and Road Development in 2-year-old Children With Typical Development Recruiting NCT04277754
41 Experimental Research Study About the Effectiveness of a Physiotherapy Program Based on Motor Imagery and Task-oriented Training in Children With Developmental Coordination Disorder Active, not recruiting NCT04176159
42 Effects of an Innovative Continuing Professional Development Intervention on Rehabilitation Clinicians' Practices to Improve Walking and Independence in Activities of Daily Living After Stroke: a Pilot Study Active, not recruiting NCT03807115
43 Effect of Kinesio Taping and Functional Movement Power Training on Neuromuscular Performance, Motor Proficiency and Functional Independence in Children With Developmental Coordination Disorder: A Randomised Controlled Trial Not yet recruiting NCT04123912
44 Rhythmical Auditory Stimulation Gait Training and Muscle Power Training for Primary School Children With Developmental Coordination Disorder: A Randomized Controlled Trial Not yet recruiting NCT03838614

Search NIH Clinical Center for Developmental Coordination Disorder

Cochrane evidence based reviews: motor skills disorders

Genetic Tests for Developmental Coordination Disorder

Anatomical Context for Developmental Coordination Disorder

MalaCards organs/tissues related to Developmental Coordination Disorder:

40
Eye, Brain, Endothelial

Publications for Developmental Coordination Disorder

Articles related to Developmental Coordination Disorder:

(show top 50) (show all 1149)
# Title Authors PMID Year
1
How Are They Doing? Neurodevelopmental Outcomes at School Age of Children Born Following Assisted Reproductive Treatments. 61
33135961 2021
2
Awareness and knowledge of developmental coordination disorder: A survey of caregivers, teachers, allied health professionals and medical professionals in Australia. 61
33140459 2021
3
Efficacy of the Cognitive Orientation to daily Occupational Performance (CO-OP) approach with and without parental coaching on activity and participation for children with developmental coordination disorder: A randomized clinical trial. 61
33508735 2021
4
Effect of comorbid developmental dyslexia on oculomotor behavior in children with developmental coordination disorder: A study with the Developmental Eye Movement test. 61
33548568 2021
5
Examining academic confidence and study support needs for university students with dyslexia and/or developmental coordination disorder. 61
33098245 2021
6
The experiences of foundation doctors with dyspraxia: a phenomenological study. 61
33559779 2021
7
Internalising symptoms in Developmental Coordination Disorder: The indirect effect of everyday executive function. 61
33360963 2021
8
A new protocol for assessing action observation and imitation abilities in children with Developmental Coordination Disorder: A feasibility and reliability study. 61
33360601 2021
9
Motor skills in children affected by strabismus. 61
32350454 2021
10
Strength, Motor Skills, and Physical Activity in Preschool-Aged Children Born Either at Less Than 30 Weeks' Gestation or at Term. 61
33517456 2021
11
Internalizing and neurodevelopmental problems in young people: Educational outcomes in a large population-based cohort of twins. 61
33596506 2021
12
Increased visual bias in children with developmental coordination disorder: Evidence from a visual-tactile temporal order judgment task. 61
33341403 2021
13
Interformat Reliability of Web-Based Parent-Rated Questionnaires for Assessing Neurodevelopmental Disorders Among Preschoolers: Cross-sectional Community Study. 61
33455899 2021
14
Does physical activity and BMI mediate the association between DCD and internalizing problems in early childhood? A partial test of the Environmental Stress Hypothesis. 61
33388656 2021
15
Emotional and behavioral problems in Japanese preschool children with motor coordination difficulties: the role of autistic traits. 61
33566188 2021
16
Inferior Auditory Time Perception in Children With Motor Difficulties. 61
33506491 2021
17
Barriers and facilitators to community participation for preschool age children born very preterm: a prospective cohort study. 61
33421112 2021
18
Coordination difficulties, IQ and psychopathology in children with high-risk copy number variants. 61
31739810 2021
19
The Relationship Between Developmental Coordination Disorder and Concurrent Deficits in Social Communication and Repetitive Behaviors Among Children with Autism Spectrum Disorder. 61
33421296 2021
20
Shared Features or Co-occurrence? Evaluating Symptoms of Developmental Coordination Disorder in Children and Adolescents with Autism Spectrum Disorder. 61
33387238 2021
21
Autonomous nervous system modulation in supine and standing postures in children with probable developmental coordination disorder. 61
33553763 2021
22
Early identification of children with/at risk of developmental coordination disorder: a scoping review. 61
33469912 2021
23
Eliciting End-State Comfort Planning in Children With and Without Developmental Coordination Disorder Using a Hammer Task: A Pilot Study. 61
33584483 2021
24
Early intervention for children with/at risk of developmental coordination disorder: a scoping review. 61
33426644 2021
25
Differences in walking and running gait in children with and without developmental coordination disorder: A systematic review and meta-analysis. 61
33160227 2021
26
The unmet clinical needs of children with developmental coordination disorder. 61
33504966 2021
27
Neural Basis and Motor Imagery Intervention Methodology Based on Neuroimaging Studies in Children With Developmental Coordination Disorders: A Review. 61
33551781 2021
28
Preliminary Improvements in Dynamic Postural Control after A Group-based Intervention Program for Children with Developmental Coordination Disorder: A Brief Report. 61
32945221 2021
29
Procedural learning and retention of audio-verbal temporal sequence is altered in children with developmental coordination disorder but cortical thickness matters. 61
32573893 2021
30
Balance control in individuals with developmental coordination disorder: A systematic review and meta-analysis. 61
33227605 2021
31
Motor skill learning in children with and without Developmental Coordination Disorder. 61
33017722 2020
32
Motor imagery and action observation for predictive control in developmental coordination disorder. 61
32735038 2020
33
The nature of coordination and control problems in children with developmental coordination disorder during ball catching: A systematic review. 61
33049460 2020
34
Altered sense of agency in children with developmental coordination disorder. 61
33086140 2020
35
Motor Impairment Increases in Children With Autism Spectrum Disorder as a Function of Social Communication, Cognitive and Functional Impairment, Repetitive Behavior Severity, and Comorbid Diagnoses: A SPARK Study Report. 61
33300285 2020
36
Unique deficit in embodied simulation in autism: An fMRI study comparing autism and developmental coordination disorder. 61
33320398 2020
37
Rates of Developmental Coordination Disorder in Children Born Very Preterm. 61
33340547 2020
38
An Exploratory Study of Teachers' Experiences in Physical Education With Children Thought to Have Developmental Coordination Disorder. 61
33321471 2020
39
Standardized motor assessments before the age of five predicting school-aged motor outcome including DCD: A systematic review. 61
33385976 2020
40
Elementary visuospatial perception deficit in children with neurodevelopmental disorders. 61
33314050 2020
41
Risk factors in early life for developmental coordination disorder: a scoping review. 61
33345317 2020
42
Perceptions of coordinated movement. 61
33171386 2020
43
Impact of a multimodal exercise program on tibial bone health in adolescents with Development Coordination Disorder: an examination of feasibility and potential efficacy. 61
33265073 2020
44
Parents' Experience with the CO-OP Approach: A Consolidation of Three Qualitative Investigations. 61
33322920 2020
45
Effects of virtual reality training intervention on predictive motor control of children with DCD - A randomized controlled trial. 61
33161293 2020
46
Human motor control: Is a subject-specific quantitative assessment of its multiple characteristics possible? A demonstrative application on children motor development. 61
33081961 2020
47
A retrospective investigation of the added clinical value of SCT symptoms on neuropsychological assessments in youth with ADHD. 61
33243064 2020
48
Supporting coordination of children with ASD using neurological music therapy: A pilot randomized control trial comparing an elastic touch-display with tambourines. 61
32950853 2020
49
International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder - Chinese (Mandarin) translation. 61
33249559 2020
50
Cognitive and motor function in developmental coordination disorder. 61
32770756 2020

Variations for Developmental Coordination Disorder

Expression for Developmental Coordination Disorder

Search GEO for disease gene expression data for Developmental Coordination Disorder.

Pathways for Developmental Coordination Disorder

Pathways related to Developmental Coordination Disorder according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.27 KCNJ11 CEBPD

GO Terms for Developmental Coordination Disorder

Sources for Developmental Coordination Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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