Aliases & Classifications for Developmental Dyspraxia

MalaCards integrated aliases for Developmental Dyspraxia:

Name: Developmental Dyspraxia 55
Developmental Coordination Disorder 74

External Ids:

UMLS 74 C0011757

Summaries for Developmental Dyspraxia

NINDS : 55 Developmental dyspraxia is a disorder characterized by an impairment in the ability to plan and carry out sensory and motor tasks. Generally, individuals with the disorder appear "out of sync" with their environment. Symptoms vary and may include poor balance and coordination, clumsiness, vision problems, perception difficulties, emotional and behavioral problems, difficulty with reading, writing, and speaking, poor social skills, poor posture, and poor short-term memory. Although individuals with the disorder may be of average or above average intelligence, they may behave immaturely.

MalaCards based summary : Developmental Dyspraxia, also known as developmental coordination disorder, is related to developmental coordination disorder and apraxia, and has symptoms including ataxia and clumsiness. An important gene associated with Developmental Dyspraxia is HDAC4 (Histone Deacetylase 4). The drugs Olive and Omega 3 Fatty Acid have been mentioned in the context of this disorder. Affiliated tissues include testes, eye and brain.

Related Diseases for Developmental Dyspraxia

Diseases related to Developmental Dyspraxia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 developmental coordination disorder 11.4
2 apraxia 10.3
3 autism 10.2
4 renpenning syndrome 1 10.0

Comorbidity relations with Developmental Dyspraxia via Phenotypic Disease Network (PDN):


Hypertension, Essential

Symptoms & Phenotypes for Developmental Dyspraxia

UMLS symptoms related to Developmental Dyspraxia:


ataxia, clumsiness

Drugs & Therapeutics for Developmental Dyspraxia

Drugs for Developmental Dyspraxia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 25)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Olive Phase 3
2 Omega 3 Fatty Acid Phase 3
3
Everolimus Approved Phase 1, Phase 2 159351-69-6 6442177 70789204
4
Miconazole Approved, Investigational, Vet_approved Phase 1, Phase 2 22916-47-8 4189
5
Sirolimus Approved, Investigational Phase 1, Phase 2 53123-88-9 46835353 6436030 5284616
6 Antifungal Agents Phase 1, Phase 2
7 Immunologic Factors Phase 1, Phase 2
8 Antibiotics, Antitubercular Phase 1, Phase 2
9 Anti-Infective Agents Phase 1, Phase 2
10 Immunosuppressive Agents Phase 1, Phase 2
11 Anti-Bacterial Agents Phase 1, Phase 2
12 Hops Approved Not Applicable
13
Methylphenidate Approved, Investigational Not Applicable 113-45-1 4158
14
Dopamine Approved 62-31-7, 51-61-6 681
15
Uric Acid Experimental, Investigational Not Applicable 69-93-2 1175
16 Pharmaceutical Solutions Not Applicable
17 Neurotransmitter Uptake Inhibitors
18 Atomoxetine Hydrochloride
19 Dopamine Agents
20 Neurotransmitter Agents
21 Central Nervous System Stimulants ,Not Applicable
22 Adrenergic Agents
23 Dopamine Uptake Inhibitors
24 insulin Not Applicable
25 Insulin, Globin Zinc Not Applicable

Interventional clinical trials:

(show all 35)
# Name Status NCT ID Phase Drugs
1 Omega-3/Omega-6 Fatty Acids for Attention-Deficit/Hyperactivity Disorder (ADHD): A Trial in Children and Adolescents Completed NCT01219309 Phase 3
2 Effect of tDCS on Postural Control of Children With DCD Recruiting NCT03892083 Phase 2, Phase 3
3 RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome Recruiting NCT02991807 Phase 1, Phase 2 RAD001;Placebo
4 Mental Attention-neuromuscular Training for Children With Developmental Coordination Disorder Unknown status NCT02397161 Not Applicable
5 Functional Movement-power Training for Children With Developmental Coordination Disorder: A Randomised Controlled Trial Unknown status NCT02393404 Not Applicable
6 The Effect of Virtual Reality on Motor Functioning and Participation Abilities Among Children With DCD Unknown status NCT02504385 Not Applicable
7 Characterization of Executive Functions and Patterns of Eye Movements in Children With Developmental Disabilities Unknown status NCT00716235
8 The Effects of a Group-based Gaze Training Intervention for Children With Developmental Coordination Disorder Completed NCT02904980 Not Applicable
9 Efficacy of the CO-OP Approach With Brazilian Children With Developmental Coordination Disorder Completed NCT03112746 Not Applicable
10 Fitball Program Versus Task-oriented Motor Program on Improving Postural Control in Developmental Coordination Disorder Completed NCT01207544 Not Applicable
11 Functional MRI Study in Children With a Developmental Coordination Disorder (DCD) and/or Developmental Dyslexia (DD) Completed NCT02393729 Not Applicable
12 A Teleintervention in Developmental Coordination Disorder Completed NCT03141333 Not Applicable
13 Characteristic of Play: Comparison Between Children With Development Coordination Disorder ( DCD) and Children With Typical Development Completed NCT01130038
14 Effects of CO-OP Approach on Activity and Participation of Brazilian Children With Developmental Coordination Disorder Completed NCT02893852 Not Applicable
15 The Role of Brain-derived Neurotropic Factor in the Relationship Between Executive Function and Physical Training Completed NCT02503579 Not Applicable
16 Developing and Evaluating a Meta-cognitive Intervention Amongst Adolescents With Neuro-development Disabilities Completed NCT03618563 Not Applicable
17 Helping Our Premature Infants ON to Better Motor Skills (HOP-ON) Completed NCT01281358 Not Applicable
18 Differences in Muscle Activity Patterns and Graphical Product Quality in Children With Graphomotor Impairment Copying and Tracing Activities on Horizontal or Vertical Surfaces Completed NCT02501590
19 Hippotherapy to Improve the Balance of Children With Movement Disorders Completed NCT01313325 Not Applicable
20 A Study of Neurophysiologically Based Occupational Therapy Intervention (NBOTI) for Feeding in the NCCU. Completed NCT00766051 Not Applicable
21 Co Morbid Attention Deficit and Hyperactivity Disorder(ADHD) and Developmental Co Ordination Disorder (DCD) Recruiting NCT03595826 Not Applicable Neurostimulant pharmaceutical drugs
22 Development of Children With DCD Before the Age of Six Recruiting NCT03690843
23 Does tDCS Improve Motor Learning in Children With DCD? Recruiting NCT03453983 Not Applicable
24 Taekwondo for Children With Developmental Coordination Disorder Recruiting NCT02635711 Not Applicable
25 DCD Imaging-Intervention Study Recruiting NCT02597751 Not Applicable
26 Reliability and Validity of a Computerized Tool to Assess Proprioception and Motor Planning Among Children With Coordination Disorders Recruiting NCT03285776
27 Neurobehavioural Development of Infants Born <30 Weeks Gestational Age Between Birth and Five Years of Age Recruiting NCT03172104
28 Identification of Neuropsychological, Genetic and Neuroimaging Markers and Treatment Response Predictors of ADHD Recruiting NCT02430896 Methylphenidate (MPH);Atomoxetine
29 Tai Chi Training for Children With ADHD Recruiting NCT02234557 Not Applicable
30 Rhythmic Motor Learning in Children With Developmental Coordination Disorders Active, not recruiting NCT03150784 Not Applicable
31 Taping for Children With and Without Movement Clumsiness Active, not recruiting NCT02945124 Not Applicable
32 Exploring the Impact and Feasibility of a Pathway to Sport and Long-term Participation in Young People Enrolling by invitation NCT02517333 Not Applicable
33 Evolution of Maternal Weight During Pregnancy and Influence on the Endothelial Function in Her Offspring Enrolling by invitation NCT02992106 Not Applicable
34 Gait and Muscle Power Training for Children With Developmental Coordination Disorder Not yet recruiting NCT03838614 Not Applicable
35 Tai Chi-muscle Power Training for Primary School Children With Developmental Coordination Disorder Not yet recruiting NCT03598478 Not Applicable

Search NIH Clinical Center for Developmental Dyspraxia

Genetic Tests for Developmental Dyspraxia

Anatomical Context for Developmental Dyspraxia

MalaCards organs/tissues related to Developmental Dyspraxia:

42
Testes, Eye, Brain, Endothelial, Bone, Heart

Publications for Developmental Dyspraxia

Articles related to Developmental Dyspraxia:

(show top 50) (show all 694)
# Title Authors Year
1
Children with Autism Spectrum Disorder, Developmental Coordination Disorder, and typical development differ in characteristics of dynamic postural control: A preliminary study. ( 30245240 )
2019
2
Do video game interventions improve motor outcomes in children with developmental coordination disorder? A systematic review using the ICF framework. ( 30651097 )
2019
3
Prevalence of suspected developmental coordination disorder and associated factors in Spanish classrooms. ( 30654220 )
2019
4
International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder. ( 30671947 )
2019
5
Risk of Developmental Coordination Disorder in Italian very preterm children at school age compared to general population controls. ( 30711366 )
2019
6
Effect of Kinesio taping on electromyographic activity of leg muscles during gait in children with developmental coordination disorder: A randomized controlled trial. ( 30732198 )
2019
7
Developmental coordination disorder continues to evolve. ( 30734941 )
2019
8
Gaze training supports self-organization of movement coordination in children with developmental coordination disorder. ( 30737438 )
2019
9
Haptic perception is altered in children with developmental coordination disorder. ( 30738812 )
2019
10
The Impact of Equine Therapy and an Audio-Visual Approach Emphasizing Rhythm and Beat Perception in Children with Developmental Coordination Disorder. ( 30789282 )
2019
11
Is Wii-based motor training better than task-specific matched training for children with developmental coordination disorder? A randomized controlled trial. ( 30794762 )
2019
12
Finger soaking enhances effects of light touch on reducing body sway in children with developmental coordination disorder. ( 30815705 )
2019
13
External focus of attention concurrently elicits optimal performance of suprapostural pole-holding task and postural stability in children with developmental coordination disorder. ( 30872044 )
2019
14
A school-based physical activity intervention for children with developmental coordination disorder: A randomized controlled trial. ( 30875607 )
2019
15
Very preterm children at risk for developmental coordination disorder have brain alterations in motor areas. ( 30891804 )
2019
16
Linear and Nonlinear Analyses of the Cardiac Autonomic Control in Children With Developmental Coordination Disorder: A Case-Control Study. ( 29623050 )
2018
17
Quality of life and psychosocial functioning in adolescents with developmental coordination disorder and attention-deficit-hyperactivity disorder. ( 29727010 )
2018
18
Evaluating the evidence for motor-based interventions in developmental coordination disorder: A systematic review and meta-analysis. ( 29413431 )
2018
19
Leg muscle activation patterns during walking and leg lean mass are different in children with and without developmental coordination disorder. ( 29275080 )
2018
20
Developmental Coordination Disorder and Its Association With Developmental Comorbidities at 6.5 Years in Apparently Healthy Children Born Extremely Preterm. ( 29868837 )
2018
21
Comparing Attention to Socially-Relevant Stimuli in Autism Spectrum Disorder and Developmental Coordination Disorder. ( 29313185 )
2018
22
Participation and needs of children with developmental coordination disorder at home and in the community: Perceptions of children and parents. ( 29245043 )
2018
23
Does the Movement Assessment Battery for Children-2 at 3 years of age predict developmental coordination disorder at 4.5 years of age in children born very preterm? ( 29653831 )
2018
24
Health-related quality of life and peer relationships in adolescents with developmental coordination disorder and attention-deficit-hyperactivity disorder. ( 29611868 )
2018
25
Effects of practice on visual finger-force control in children at risk of developmental coordination disorder. ( 29699866 )
2018
26
Sensory and motor differences in Autism Spectrum Conditions and developmental coordination disorder in children: A cross-syndrome study. ( 29408162 )
2018
27
Developmental coordination disorder, psychopathology and IQ in 22q11.2 deletion syndrome. ( 29433607 )
2018
28
Nature of motor impairments in autism spectrum disorder: A comparison with developmental coordination disorder. ( 29923455 )
2018
29
Corticospinal excitability during motor imagery is reduced in young adults with developmental coordination disorder. ( 29195158 )
2018
30
Motor Competence Levels and Prevalence of Developmental Coordination Disorder in Spanish Children: The MOVI-KIDS Study. ( 29864209 )
2018
31
Developmental coordination disorder: the role of executive functions. ( 29333599 )
2018
32
Differences in accuracy and vividness of motor imagery in children with and without Developmental Coordination Disorder. ( 29966867 )
2018
33
Subtyping children with developmental coordination disorder based on physical fitness outcomes. ( 29852337 )
2018
34
Success in Adults With Probable Developmental Coordination Disorder Using Structural Equation Modeling. ( 29426379 )
2018
35
Is auditory perceptual timing a core deficit of developmental coordination disorder? ( 29741273 )
2018
36
Motor Skill Interventions in Children with Developmental Coordination Disorder: A Systematic Review and Meta-Analysis. ( 29329670 )
2018
37
The brains of children with developmental coordination disorder. ( 29298759 )
2018
38
Interhemispheric Cortical Inhibition Is Reduced in Young Adults With Developmental Coordination Disorder. ( 29628909 )
2018
39
Motor Planning and Gait Coordination Assessments for Children with Developmental Coordination Disorder. ( 29851530 )
2018
40
Health-related quality of life of children with Developmental Coordination Disorder. ( 29907374 )
2018
41
Variability in coordination patterns in children with developmental coordination disorder (DCD). ( 29957424 )
2018
42
Developmental dysgraphia is often associated with minor neurological dysfunction in children with developmental coordination disorder (DCD). ( 29605507 )
2018
43
Differential activation of brain areas in children with developmental coordination disorder during tasks of manual dexterity: An ALE meta-analysis. ( 29339004 )
2018
44
We12BFit!-Improving lifestyle physical activity in children aged 7-12 years with developmental coordination disorder: protocol of a multicentre single-arm mixed-method study. ( 29950462 )
2018
45
Functional brain correlates of motor response inhibition in children with developmental coordination disorder and attention deficit/hyperactivity disorder. ( 29655169 )
2018
46
Behavioral Own-Body-Transformations in Children and Adolescents With Typical Development, Autism Spectrum Disorder, and Developmental Coordination Disorder. ( 29887813 )
2018
47
Physiological characteristics, self-perceptions, and parental support of physical activity in children with, or at risk of, developmental coordination disorder. ( 29914720 )
2018
48
Atypical inter-hemispheric communication correlates with altered motor inhibition during learning of a new bimanual coordination pattern in developmental coordination disorder. ( 28440058 )
2018
49
Developmental coordination disorder and its cause: The road less travelled. ( 28465073 )
2018
50
Local dynamic stability during treadmill walking can detect children with developmental coordination disorder. ( 29028627 )
2018

Variations for Developmental Dyspraxia

Expression for Developmental Dyspraxia

Search GEO for disease gene expression data for Developmental Dyspraxia.

Pathways for Developmental Dyspraxia

GO Terms for Developmental Dyspraxia

Sources for Developmental Dyspraxia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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