IDDM19
MCID: DBT077
MIFTS: 16

Diabetes Mellitus, Insulin-Dependent, 19 (IDDM19)

Categories: Endocrine diseases, Genetic diseases, Metabolic diseases, Rare diseases

Aliases & Classifications for Diabetes Mellitus, Insulin-Dependent, 19

MalaCards integrated aliases for Diabetes Mellitus, Insulin-Dependent, 19:

Name: Diabetes Mellitus, Insulin-Dependent, 19 57 74 13 72
Iddm19 57 12 74
Insulin-Dependent Diabetes Mellitus 19 12
Type 1 Diabetes Mellitus 19 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0110756
OMIM 57 610155
MeSH 44 D003922
ICD10 33 E10
MedGen 42 C1857808
UMLS 72 C1857808

Summaries for Diabetes Mellitus, Insulin-Dependent, 19

UniProtKB/Swiss-Prot : 74 Diabetes mellitus, insulin-dependent, 19: A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical features are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.

MalaCards based summary : Diabetes Mellitus, Insulin-Dependent, 19, is also known as iddm19. An important gene associated with Diabetes Mellitus, Insulin-Dependent, 19 is IFIH1 (Interferon Induced With Helicase C Domain 1). Affiliated tissues include kidney, eye and thyroid.

Disease Ontology : 12 A type 1 diabetes mellitus that has material basis in mutation of the locus at chromosome 2q24.3.

More information from OMIM: 610155

Symptoms & Phenotypes for Diabetes Mellitus, Insulin-Dependent, 19

Clinical features from OMIM:

610155

Drugs & Therapeutics for Diabetes Mellitus, Insulin-Dependent, 19

Search Clinical Trials , NIH Clinical Center for Diabetes Mellitus, Insulin-Dependent, 19

Genetic Tests for Diabetes Mellitus, Insulin-Dependent, 19

Anatomical Context for Diabetes Mellitus, Insulin-Dependent, 19

MalaCards organs/tissues related to Diabetes Mellitus, Insulin-Dependent, 19:

41
Kidney, Eye, Thyroid

Publications for Diabetes Mellitus, Insulin-Dependent, 19

Articles related to Diabetes Mellitus, Insulin-Dependent, 19:

# Title Authors PMID Year
1
Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes. 8
19264985 2009
2
IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells. 8
18927125 2009
3
A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. 8
16699517 2006
4
Use of population based background rates of disease to assess vaccine safety in childhood and mass immunisation in Denmark: nationwide population based cohort study. 38
22988304 2012
5
Influence of fat intake on body composition, lipemia and glycemia of type 1 diabetics. 38
22072360 2011
6
Measurement of thyroid-stimulating immunoglobulins by incorporation of tritiated-adenine into intact FRTL-5 cells: a viable alternative to radioimmunoassay for the measurement of cAMP. 38
1363083 1992

Variations for Diabetes Mellitus, Insulin-Dependent, 19

Expression for Diabetes Mellitus, Insulin-Dependent, 19

Search GEO for disease gene expression data for Diabetes Mellitus, Insulin-Dependent, 19.

Pathways for Diabetes Mellitus, Insulin-Dependent, 19

GO Terms for Diabetes Mellitus, Insulin-Dependent, 19

Sources for Diabetes Mellitus, Insulin-Dependent, 19

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....