MCID: DBT002
MIFTS: 46

Diabetic Autonomic Neuropathy

Categories: Neuronal diseases

Aliases & Classifications for Diabetic Autonomic Neuropathy

MalaCards integrated aliases for Diabetic Autonomic Neuropathy:

Name: Diabetic Autonomic Neuropathy 12 56 15 74
Diabetic Neuropathies 45 74

Classifications:



External Ids:

Disease Ontology 12 DOID:11503
MeSH 45 D003929
NCIt 51 C27068
SNOMED-CT 69 50620007

Summaries for Diabetic Autonomic Neuropathy

MalaCards based summary : Diabetic Autonomic Neuropathy, also known as diabetic neuropathies, is related to diabetic neuropathy and microvascular complications of diabetes 1, and has symptoms including sciatica and neuralgia. An important gene associated with Diabetic Autonomic Neuropathy is AKR1B1 (Aldo-Keto Reductase Family 1 Member B), and among its related pathways/superpathways are PI3K-Akt signaling pathway and p75(NTR)-mediated signaling. The drugs Pregabalin and Isosorbide Dinitrate have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and testes, and related phenotype is vision/eye.

Related Diseases for Diabetic Autonomic Neuropathy

Diseases related to Diabetic Autonomic Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 143)
# Related Disease Score Top Affiliating Genes
1 diabetic neuropathy 33.3 AKR1B1 EPO INS NGF NTF3
2 microvascular complications of diabetes 1 32.6 AKR1B1 INS NTF3
3 microvascular complications of diabetes 5 32.1 AKR1B1 INS
4 autonomic neuropathy 31.5 AKR1B1 INS NGF
5 diabetic polyneuropathy 29.9 AKR1B1 NGF NTF3
6 peripheral nervous system disease 29.6 AKR1B1 INS NGF
7 neurogenic arthropathy 29.5 HBA1 NGF
8 microvascular complications of diabetes 3 11.3
9 microvascular complications of diabetes 4 11.3
10 microvascular complications of diabetes 6 11.3
11 microvascular complications of diabetes 7 11.3
12 neuropathy 11.1
13 microvascular complications of diabetes 2 11.0
14 abducens nerve disease 11.0
15 argyll robertson pupil 11.0
16 syncope 11.0
17 fainting 11.0
18 hypoglycemia 10.3
19 polyneuropathy 10.3
20 sheehan syndrome 10.2 EPO INS
21 plethora of newborn 10.2 EPO INS
22 pure autonomic failure 10.2
23 fetal erythroblastosis 10.2 EPO INS
24 depression 10.2
25 type 1 diabetes mellitus 7 10.1 HBA1 INS
26 type 1 diabetes mellitus 11 10.1 HBA1 INS
27 postherpetic neuralgia 10.1
28 functional gastric disease 10.1 INS MLNR
29 ischemia 10.1
30 cardiac conduction defect 10.1
31 diabetes mellitus 10.1
32 iritis 10.1
33 hyperglycemia 10.1
34 uremia 10.1 EPO INS
35 hemoglobin h disease 10.1 EPO HBA1
36 hemoglobinopathy 10.1 EPO HBA1
37 autonomic nervous system disease 10.1 INS NGF
38 microcytic anemia 10.0 EPO HBA1
39 endocrine organ benign neoplasm 10.0 INS NGF
40 sickle cell anemia 10.0 EPO HBA1
41 myocardial infarction 10.0
42 sexual disorder 10.0
43 ocular dominance 10.0 NGF NTF3
44 anxiety 10.0
45 neuritis 10.0
46 fibromyalgia 10.0
47 pain - chronic 10.0
48 retinal vascular disease 10.0 AKR1B1 HBA1 INS
49 restless legs syndrome 10.0
50 keratoconjunctivitis 9.9 AOC1 NGF

Graphical network of the top 20 diseases related to Diabetic Autonomic Neuropathy:



Diseases related to Diabetic Autonomic Neuropathy

Symptoms & Phenotypes for Diabetic Autonomic Neuropathy

UMLS symptoms related to Diabetic Autonomic Neuropathy:


sciatica, neuralgia

MGI Mouse Phenotypes related to Diabetic Autonomic Neuropathy:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 vision/eye MP:0005391 9.02 AKR1B1 AOC1 INS NGF NTF3

Drugs & Therapeutics for Diabetic Autonomic Neuropathy

Drugs for Diabetic Autonomic Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 501)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 148553-50-8 5486971
2
Isosorbide Dinitrate Approved, Investigational Phase 4,Phase 3 87-33-2 6883
3
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 10102-43-9 145068
4
AT-101 Approved, Investigational Phase 4,Phase 3 90141-22-3, 652-67-5 12597
5
Saxagliptin Approved Phase 4 361442-04-8 11243969
6
Metronidazole Approved Phase 4 443-48-1 4173
7
Piperacillin Approved Phase 4,Phase 3 66258-76-2 43672
8
Linezolid Approved, Investigational Phase 4 165800-03-3 441401
9
Levofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2 100986-85-4 149096
10
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Not Applicable 26787-78-0 33613
11
Tazobactam Approved Phase 4,Phase 3 89786-04-9 123630
12
Ofloxacin Approved Phase 4,Phase 3,Phase 2 82419-36-1 4583
13
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
14
Aztreonam Approved Phase 4 78110-38-0 5742832 5362041
15
Clavulanate Approved, Vet_approved Phase 4,Phase 3,Not Applicable 58001-44-8 5280980
16
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 137-58-6 3676
17
tannic acid Approved Phase 4,Phase 3,Phase 2,Not Applicable 1401-55-4
18
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 94-09-7, 1994-09-7 2337
19
Nabilone Approved, Investigational Phase 4,Phase 3 51022-71-0 5284592
20
Methylcobalamin Approved, Experimental, Investigational Phase 4,Phase 3,Not Applicable 13422-55-4
21
Hydroxocobalamin Approved Phase 4,Phase 3,Not Applicable 13422-51-0 11953898 15589840
22
leucovorin Approved Phase 4,Not Applicable 58-05-9 6006 143
23
Ciprofloxacin Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 85721-33-1 2764
24
Trimethoprim Approved, Vet_approved Phase 4,Not Applicable 738-70-5 5578
25
Sulfamethoxazole Approved Phase 4,Not Applicable 723-46-6 5329
26
Quinapril Approved, Investigational Phase 4 85441-61-8 54892
27
Bromocriptine Approved, Investigational Phase 4 25614-03-3 31101
28
Dopamine Approved Phase 4,Phase 3,Phase 2,Not Applicable 62-31-7, 51-61-6 681
29
Gabapentin Approved, Investigational Phase 4,Phase 3,Phase 2 60142-96-3 3446
30
Acetaminophen Approved Phase 4,Phase 3 103-90-2 1983
31
Tramadol Approved, Investigational Phase 4,Phase 3 27203-92-5 33741
32
Norepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-41-2 439260
33
Amitriptyline Approved Phase 4,Phase 2,Not Applicable 50-48-6 2160
34
Sodium Citrate Approved, Investigational Phase 4,Phase 3,Not Applicable 68-04-2
35
Carbamazepine Approved, Investigational Phase 4 298-46-4 2554
36
Acetylcholine Approved, Investigational Phase 4,Phase 2,Not Applicable 51-84-3 187
37
Atorvastatin Approved Phase 4,Phase 2 134523-00-5 60823
38
Indapamide Approved Phase 4 26807-65-8 3702
39
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
40
Irbesartan Approved, Investigational Phase 4 138402-11-6 3749
41
Cefoxitin Approved Phase 4 35607-66-0 441199
42
Cefotaxime Approved Phase 4 63527-52-6 456256 5742673
43
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
44
Rifampicin Approved Phase 4 13292-46-1 5381226 5458213
45
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 564-25-0 54671203
46
Fusidic Acid Approved, Investigational Phase 4,Early Phase 1 6990-06-3 3000226
47
Cefepime Approved, Investigational Phase 4 88040-23-7 5479537
48
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2,Not Applicable 55-56-1 2713 9552079
49
Petrolatum Approved, Investigational Phase 4,Phase 2 8009-03-8
50
Sulbactam Approved Phase 4 68373-14-8

Interventional clinical trials:

(show top 50) (show all 935)
# Name Status NCT ID Phase Drugs
1 Inspiratory Muscle Training in Patients With Autonomic Neuropathic Unknown status NCT00752440 Phase 4
2 Evaluation of the Impact of Training on Outcome Measures in Subjects With Painful Diabetic Neuropathy Unknown status NCT01770964 Phase 4 Pregabalin;placebo
3 Bi-Axial Rotating Magnetic Field Therapy in Refractory Neuropathic Foot Pain Secondary to Diabetic Peripheral Neuropathy Unknown status NCT00123136 Phase 4
4 Influence of Nitrates on Bone Remodeling and Endothelial Function in Patients With Type 2 Diabetes Mellitus Unknown status NCT02011620 Phase 4
5 Maggot Debridement Therapy Versus Conventional Dressing Therapy to Treat Diabetic Foot Ulcers Unknown status NCT02816749 Phase 4
6 Dipeptidyl Peptidase 4 Inhibition Facilitate Healing of Diabetic Ulcers Unknown status NCT02742233 Phase 4 saxagliptin;placebo
7 A Comparative Efficacy Study of DermaPure™ to Treat Diabetic Foot Ulcers Unknown status NCT02081352 Phase 4
8 Efficacy and Safety of Garamycin® Sponge (Gentamicin-Collagen Sponge) in Diabetic Patients With a Moderate or Severe Foot Ulcer Infection Unknown status NCT01951768 Phase 4 Garamycin Sponge (Gentamicin-Collagen sponge);Systemic Antibiotic
9 Clinical Evaluation of the SNaP Wound Care System Unknown status NCT01113658 Phase 4
10 Efficacy of Administration of ACE-Inhibition on Autonomic and Peripheral Neuropathy in Patients With Diabetes Mellitus Completed NCT03031834 Phase 4 Quinapril
11 Bromocriptine-QR Therapy on Sympathetic Tone and Vascular Biology in Type 2 Diabetes Subjects Completed NCT02682901 Phase 4 Cycloset;Placebo
12 A Randomized Double-Blind Study Testing the Effects of Pregabalin on Diabetic Neuropathy Completed NCT00573261 Phase 4 Pregabalin;Placebo
13 Frequency Modulated Neural Stimulation (FREMS) in Symptomatic Diabetic Neuropathy Completed NCT01628627 Phase 4
14 A Study on the Efficacy and Safety of Gabapentin in the Treatment of Patients With Painful Diabetic Neuropathy Completed NCT00644748 Phase 4 gabapentin
15 A Study to Compare Safety and Efficacy of Tramadol Hydrochloride/Acetaminophen With Gabapentin in Participants With Diabetic Neuropathy Completed NCT00634543 Phase 4 Tramadol hydrochloride/ Acetaminophen;Gabapentin
16 Effect of Pulsing Electrical Fields on Lower Extremity Diabetic Neuropathy: A Pilot, Open-Label Study Completed NCT00614341 Phase 4
17 Alpha Lipoic Acid for Treatment of Diabetic Neuropathy Completed NCT02439879 Phase 4 Alpha lipoic acid
18 A Study of the Effectiveness And Safety Of Lidoderm® As Add-On Treatment in Patients With Postherpetic Neuralgia, Diabetic Neuropathy, or Low Back Pain Completed NCT00904020 Phase 4 Lidoderm
19 Maintenance of Effect of Duloxetine in Patients With Diabetic Peripheral Neuropathic Pain (DPNP) Completed NCT00322621 Phase 4 Duloxetine
20 Training "Pain Connoisseurs" for Efficient Analgesic Proof-of-Concept Studies Completed NCT02842554 Phase 4 Drug Placebo Administration
21 Evaluation of Rocker sOles in Diabetis Completed NCT02891928 Phase 4
22 Evaluation of the Efficacy of Cesamet™ for the Treatment of Pain in Patients With Diabetic Peripheral Neuropathy Completed NCT00380913 Phase 4 Cesamet™ (nabilone)
23 Tolerability of Switching to Duloxetine for the Management of Diabetic Nerve Pain Completed NCT00266643 Phase 4 duloxetine hydrochloride
24 An Open Label, Dose Finding Trial of Viagra for the Treatment of Neuropathic Pain (in Diabetes Mellitus) Completed NCT00194909 Phase 4 sildenafil (Viagra)
25 An Open-Label Comparison of Duloxetine to Other Alternatives for the Management of Diabetic Peripheral Neuropathic Pain Completed NCT00385671 Phase 4 duloxetine hydrochloride;pregabalin;gabapentin
26 Pregabalin in the Treatment of Pain Due to Diabetic Peripheral Neuropathy Completed NCT00159679 Phase 4 Pregabalin
27 A Study To Evaluate Pregabalin In Patients With Painful Diabetic Peripheral Neuropathy (DPN) Completed NCT00156078 Phase 4 pregabalin
28 A Study of the Efficacy and Safety of Pregabalin for the Treatment of Diabetic Peripheral Neuropathy or Postherpetic Neuralgia Completed NCT00629681 Phase 4 Pregabalin
29 Lovaza® and Microvascular Function in Type 2 Diabetes Completed NCT00931879 Phase 4 omega-3-ethyl esters;Placebo
30 Anodyne Therapy in Diabetic Sensory Neuropathy Completed NCT00120341 Phase 4
31 Efficacy and Tolerability of Carbamazepine CR in Diabetic Neuropathy Pain Completed NCT01089855 Phase 4 Carbamazepine
32 Duloxetine in Patients With Diabetic in Peripheral Neuropathic Pain With or Without Co-morbid Major Depressive Disorder Completed NCT00844194 Phase 4 Duloxetine 60 mg QD;Duloxetine 60 mg QD;Duloxetine 30 mg QD;Duloxetine 30 mg QD;Duloxetine 90 mg QD;Duloxetine 90 mg QD;Duloxetine 60 mg QD;Duloxetine 60 mg QD;Duloxetine 120 mg QD;Duloxetine 30 mg QD;Duloxetine 30 mg QD;Duloxetine 120 mg QD
33 PRELIMINARY EVALUATION OF PHARMACOLOGICAL LOWERING OF AGEs Completed NCT02249897 Phase 4 CHOLESTYRAMINE
34 A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions Completed NCT00904202 Phase 4 Placebo Capsules + Placebo Patch;Placebo capsules + Lidoderm®;Gabapentin + Placebo;Gabapentin + Lidoderm®;Gabapentin 300 mg capsules 1800 mg/day + placebo patch;Gabapentin 1800 mg/day + Lidoderm patch
35 Lidoderm® (Lidocaine Patch 5%) in Diabetic and Idiopathic Neuropathy Completed NCT00903851 Phase 4 Lidoderm
36 Safety and Efficacy of Mecobalamin Injection in Peripheral Neuropathies Patients (Study JGAZSY091109) Completed NCT01192113 Phase 4 Mecobalamin IV Injection;Mecobalamin IM injection;Mecobalamin IV or IM injection
37 A Study of Duloxetine (LY248686) in Participants With Diabetic Peripheral Neuropathic Pain (DPNP) Completed NCT02417935 Phase 4 Duloxetine;Pregabalin;Placebo
38 Efficacy and Safety of Gabapentin/B-complex Versus Pregabalin in Diabetic Peripheral Neuropathy Pain Management Completed NCT01364298 Phase 4 Gabapentin/B-complex;Pregabalin
39 Study of Metanx® in Subjects With Type 2 Diabetic Peripheral Neuropathy (DPN) Completed NCT00726713 Phase 4
40 Safety of Pregabalin in the Treatment of Pain Due to Diabetic Peripheral Neuropathy Completed NCT00159731 Phase 4 Pregabalin
41 Study of Oasis Ultra in Diabetic Foot Ulcers Completed NCT01835379 Phase 4
42 Pregabalin Treatment Of Peripheral Neuropathic Pain Associated With Diabetic Peripheral NeP (DPN), Postherpetic Neuralgia (PHN), HIV-related NeP (HIV), and Chemotherapy Induced NeP Completed NCT00407511 Phase 4 Pregabalin
43 The InsuPad in Daily Life Study - Effect of Local Heating on Postprandial Glucose Excursions Using the InsuPad Device Completed NCT01352767 Phase 4
44 Botulinum Toxin in Peripheral Neuropathic Pain Completed NCT01251211 Phase 4 botulinum toxin type A
45 Renal Denervation in Diabetic Nephropathy Completed NCT01588795 Phase 4 Standardized antiproteinuric medication regimen includes an angiotensin receptor blocker , a diuretic , 25OH vitamin D3 and a statin
46 Pharmacokinetics of Two Formulation of Pregabalin Completed NCT03712475 Phase 4 Pregabalin
47 GrafixPRIME® for the Treatment of Chronic Diabetic Foot Ulcers Completed NCT02675855 Phase 4
48 Use of Santyl in Diabetic Foot Ulcers Completed NCT02581488 Phase 4
49 GrafixCORE®: Open-Label Study to Evaluate the Safety and Efficacy of GrafixCORE® for Complex Diabetic Foot Wounds Completed NCT02260609 Phase 4
50 LeucoPatch in the Management of Hard-to-heal Diabetic Foot Ulcers Completed NCT02224742 Phase 4

Search NIH Clinical Center for Diabetic Autonomic Neuropathy

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: diabetic neuropathies

Genetic Tests for Diabetic Autonomic Neuropathy

Anatomical Context for Diabetic Autonomic Neuropathy

MalaCards organs/tissues related to Diabetic Autonomic Neuropathy:

42
Skin, Bone, Testes, Heart, Endothelial, Bone Marrow, Spinal Cord

Publications for Diabetic Autonomic Neuropathy

Articles related to Diabetic Autonomic Neuropathy:

(show top 50) (show all 370)
# Title Authors Year
1
Diabetic neuropathies influence recovery from hip-fracture surgery in older persons with diabetes. ( 30738920 )
2019
2
Diabetic autonomic neuropathy resulting in sexual dysfunction. ( 30256272 )
2018
3
Diabetic autonomic neuropathy resulting in sexual dysfunction. ( 30320635 )
2018
4
Catechin attenuates diabetic autonomic neuropathy in streptozotocin induced diabetic rats. ( 30372853 )
2018
5
Suppression Failure of Cortisol Secretion by Dexamethasone May Occur in Glucagon-like Peptide-1 Receptor Agonist-treated Patients with Diabetic Autonomic Neuropathy. ( 30568127 )
2018
6
Managing supine hypertension in a patient with non-diabetic autonomic neuropathy receiving droxidopa for neurogenic orthostatic hypotension. ( 28623420 )
2017
7
Treatment of Diabetic Autonomic Neuropathy in Older Adults with Diabetes Mellitus. ( 28107120 )
2016
8
Inflammation as a Therapeutic Target for Diabetic Neuropathies. ( 26897744 )
2016
9
Current Ideas on the Treatment Of Diabetic Neuropathies. ( 30058872 )
2016
10
Morphologic Changes in Autonomic Nerves in Diabetic Autonomic Neuropathy. ( 26706915 )
2015
11
Inspiratory muscle training in patients with diabetic autonomic neuropathy: a randomized clinical trial. ( 25982993 )
2015
12
Role of Microcirculatory Disturbances and Diabetic Autonomic Neuropathy in Takotsubo Cardiomyopathy. ( 26468716 )
2015
13
Sensory manifestations of diabetic neuropathies: anatomical and clinical correlations. ( 25614497 )
2015
14
Identifying Common Genetic Risk Factors of Diabetic Neuropathies. ( 26074879 )
2015
15
Diabetic Neuropathies. ( 26502765 )
2015
16
Association of diabetic autonomic neuropathy with red blood cell aldose reductase activity. ( 24485209 )
2014
17
Diabetic autonomic neuropathy. ( 25410215 )
2014
18
Disproportionate pupillary involvement in diabetic autonomic neuropathy. ( 25377131 )
2014
19
CORNEAL confocal microscopy for the diagnosis of diabetic autonomic neuropathy. ( 25556884 )
2014
20
Calcium signalling in sensory neurones and peripheral glia in the context of diabetic neuropathies. ( 25149565 )
2014
21
Diabetic neuropathies. ( 25299279 )
2014
22
Diabetic autonomic neuropathy. ( 24095132 )
2013
23
Diabetic autonomic neuropathy affects symptom generation and brain-gut axis. ( 24026548 )
2013
24
Alpha lipoic acid and glycaemic control in diabetic neuropathies at type 2 diabetes treatment. ( 23678828 )
2013
25
Diabetic neuropathies: diagnosis and management. ( 24458095 )
2013
26
What is the ideal biological marker in diagnosis of diabetic neuropathies? ( 24843646 )
2013
27
Muscle strength and ankle mobility for the gait parameters in diabetic neuropathies. ( 23274122 )
2013
28
Mortality after acute myocardial infarction: significance of cardiovascular diabetic autonomic neuropathy (CDAN). ( 23097964 )
2012
29
Diabetic autonomic neuropathy. ( 23393679 )
2012
30
Highlights in clinical autonomic neuroscience: latest developments in the early detection of diabetic autonomic neuropathy. ( 22306250 )
2012
31
The diabetic neuropathies: practical and rational therapy. ( 23117944 )
2012
32
The relationship between diabetic autonomic neuropathy and diabetic risk factors in a Taiwanese population. ( 21986117 )
2011
33
The effect of diabetic autonomic neuropathy on P-wave duration, dispersion and atrial fibrillation. ( 22291825 )
2011
34
Recommendations for the use of cardiovascular tests in diagnosing diabetic autonomic neuropathy. ( 21247746 )
2011
35
Vasopressin release induced by hypothension is blunted in patients with diabetic autonomic neuropathy. ( 20370555 )
2011
36
Severe orthostatic hypotension in a diabetic patient may not be due to diabetic autonomic neuropathy. ( 21902089 )
2011
37
Effects of an exercise program on balance and trunk proprioception in older adults with diabetic neuropathies. ( 21561371 )
2011
38
Effect of acute hyperglycaemia on sensory processing in diabetic autonomic neuropathy. ( 20624170 )
2010
39
Gastric mucosal nerve density: a biomarker for diabetic autonomic neuropathy? ( 20837965 )
2010
40
Different effects of diabetic autonomic neuropathy on regional transcutaneous oxygen tension in patients with peripheral arterial disease. ( 21466127 )
2010
41
Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies. ( 20599608 )
2010
42
Diabetic neuropathies: update on definitions, diagnostic criteria, estimation of severity, and treatments. ( 20876709 )
2010
43
Cough reflex sensitivity in adolescents with diabetic autonomic neuropathy. ( 20156724 )
2009
44
New insights in diabetic autonomic neuropathy in children and adolescents. ( 19734243 )
2009
45
A pharmacologic pupillary test in the diagnosis of diabetic autonomic neuropathy. ( 20046691 )
2009
46
Erythropoietin and its carbamylated derivative prevent the development of experimental diabetic autonomic neuropathy in STZ-induced diabetic NOD-SCID mice. ( 17967455 )
2008
47
Dynamic cerebral autoregulation assessment using chaotic analysis in diabetic autonomic neuropathy. ( 17874153 )
2008
48
The impact of diabetic autonomic neuropathy on the incretin effect. ( 18376350 )
2008
49
The spectrum of diabetic neuropathies. ( 18194747 )
2008
50
Diabetic neuropathies: components of etiology. ( 18601656 )
2008

Variations for Diabetic Autonomic Neuropathy

Expression for Diabetic Autonomic Neuropathy

Search GEO for disease gene expression data for Diabetic Autonomic Neuropathy.

Pathways for Diabetic Autonomic Neuropathy

Pathways related to Diabetic Autonomic Neuropathy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.76 EPO INS NGF NTF3
2
Show member pathways
11.14 NGF NTF3
3
Show member pathways
11.04 NGF NTF3
4 10.84 EPO INS
5 10.61 NGF NTF3

GO Terms for Diabetic Autonomic Neuropathy

Cellular components related to Diabetic Autonomic Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.43 AOC1 EPO HBA1 INS NGF NTF3
2 extracellular space GO:0005615 9.17 AKR1B1 AOC1 EPO HBA1 INS NGF

Biological processes related to Diabetic Autonomic Neuropathy according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.49 INS NTF3
2 neuron projection morphogenesis GO:0048812 9.48 NGF NTF3
3 modulation of chemical synaptic transmission GO:0050804 9.46 NGF NTF3
4 regulation of signaling receptor activity GO:0010469 9.46 EPO INS NGF NTF3
5 acute-phase response GO:0006953 9.43 EPO INS
6 activation of protein kinase B activity GO:0032148 9.4 INS NTF3
7 peripheral nervous system development GO:0007422 9.37 NGF NTF3
8 regulation of neuron differentiation GO:0045664 9.32 NGF NTF3
9 positive regulation of Ras protein signal transduction GO:0046579 9.26 EPO NGF
10 nerve development GO:0021675 8.96 NGF NTF3
11 nerve growth factor signaling pathway GO:0038180 8.62 NGF NTF3

Sources for Diabetic Autonomic Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....