MCID: DBT003
MIFTS: 23

Diabetic Peripheral Angiopathy

Categories: Metabolic diseases

Aliases & Classifications for Diabetic Peripheral Angiopathy

MalaCards integrated aliases for Diabetic Peripheral Angiopathy:

Name: Diabetic Peripheral Angiopathy 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:10182
ICD9CM 34 250.7
SNOMED-CT 67 982001
UMLS 71 C0011871

Summaries for Diabetic Peripheral Angiopathy

MalaCards based summary : Diabetic Peripheral Angiopathy is related to heterophyiasis and toxicodendron dermatitis. An important gene associated with Diabetic Peripheral Angiopathy is FBLN5 (Fibulin 5), and among its related pathways/superpathways are Photodynamic therapy-induced NF-kB survival signaling and AGE-RAGE signaling pathway in diabetic complications. Related phenotypes are cellular and growth/size/body region

Related Diseases for Diabetic Peripheral Angiopathy

Diseases related to Diabetic Peripheral Angiopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 84)
# Related Disease Score Top Affiliating Genes
1 heterophyiasis 10.1 SELE ICAM1
2 toxicodendron dermatitis 10.1 SELE ICAM1
3 macular degeneration, age-related, 9 10.1 SELE ICAM1
4 rheumatoid vasculitis 10.1 SELE ICAM1
5 mooren's ulcer 10.1 SELE ICAM1
6 plummer's disease 10.1 SELE ICAM1
7 sympathetic ophthalmia 10.1 SELE ICAM1
8 hydrocele 10.1 SELE ICAM1
9 endophthalmitis 10.1 SELE ICAM1
10 leukostasis 10.0 SELE ICAM1
11 polyarteritis nodosa 10.0 SELE ICAM1
12 crescentic glomerulonephritis 10.0 SELE ICAM1
13 plasmodium vivax malaria 10.0 SELE ICAM1
14 cutaneous lupus erythematosus 10.0 SELE ICAM1
15 carotid stenosis 10.0 SELE ICAM1
16 grange syndrome 10.0 SELE F3
17 post-thrombotic syndrome 10.0 ICAM1 F3
18 allergic contact dermatitis 10.0 SELE ICAM1
19 intermediate coronary syndrome 10.0 ICAM1 F3
20 contact dermatitis 10.0 SELE ICAM1
21 limb ischemia 10.0 SELE ICAM1
22 leukocyte adhesion deficiency, type i 10.0 SELE ICAM1
23 gingivitis 10.0 SELE ICAM1
24 vein disease 9.9 ICAM1 F3
25 mastitis 9.9 SELE ICAM1
26 thrombotic thrombocytopenic purpura 9.9 SELE F3
27 carotid artery disease 9.9 SELE F3
28 plasmodium falciparum malaria 9.9 SELE ICAM1
29 peripheral artery disease 9.9 ICAM1 F3
30 antiphospholipid syndrome 9.8 SELE F3
31 african tick-bite fever 9.8 SELE IL13
32 disseminated intravascular coagulation 9.8 SELE F3
33 pollen allergy 9.8 IL13 ICAM1
34 localized scleroderma 9.8 SELE IL13
35 nasal cavity disease 9.8 IL13 ICAM1
36 allergic conjunctivitis 9.8 IL13 ICAM1
37 conjunctivitis 9.8 IL13 ICAM1
38 common cold 9.8 IL13 ICAM1
39 synovitis 9.8 SELE ICAM1
40 nose disease 9.8 IL13 ICAM1
41 keratoconjunctivitis 9.8 IL13 ICAM1
42 splenic disease 9.7 IL13 F3
43 pulmonary edema 9.7 IL13 ICAM1
44 dengue hemorrhagic fever 9.7 IL13 F3
45 parasitic protozoa infectious disease 9.6 IL13 ICAM1
46 idiopathic interstitial pneumonia 9.6 IL13 ICAM1
47 peripheral vascular disease 9.6 SELE F3
48 urticaria 9.6 SELE IL13
49 trypanosomiasis 9.6 SELE ICAM1
50 shwartzman phenomenon 9.6 SELE ICAM1 F3

Comorbidity relations with Diabetic Peripheral Angiopathy via Phenotypic Disease Network (PDN):


Acute Cystitis Heart Disease
Hypertension, Essential Peripheral Vascular Disease

Graphical network of the top 20 diseases related to Diabetic Peripheral Angiopathy:



Diseases related to Diabetic Peripheral Angiopathy

Symptoms & Phenotypes for Diabetic Peripheral Angiopathy

MGI Mouse Phenotypes related to Diabetic Peripheral Angiopathy:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.85 CYP27B1 F3 FBLN5 ICAM1 IL13 SELE
2 growth/size/body region MP:0005378 9.8 CYP27B1 F3 FBLN5 ICAM1 IL13 SELE
3 homeostasis/metabolism MP:0005376 9.73 CYP27B1 F3 FBLN5 ICAM1 IL13 SELE
4 integument MP:0010771 9.63 CYP27B1 F3 FBLN5 ICAM1 IL13 SELE
5 muscle MP:0005369 9.26 F3 FBLN5 ICAM1 IL13
6 respiratory system MP:0005388 8.92 F3 FBLN5 IL13 SELE

Drugs & Therapeutics for Diabetic Peripheral Angiopathy

Search Clinical Trials , NIH Clinical Center for Diabetic Peripheral Angiopathy

Genetic Tests for Diabetic Peripheral Angiopathy

Anatomical Context for Diabetic Peripheral Angiopathy

Publications for Diabetic Peripheral Angiopathy

Variations for Diabetic Peripheral Angiopathy

Expression for Diabetic Peripheral Angiopathy

Search GEO for disease gene expression data for Diabetic Peripheral Angiopathy.

Pathways for Diabetic Peripheral Angiopathy

Pathways related to Diabetic Peripheral Angiopathy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.2 SELE ICAM1
2 11.13 SELE ICAM1 F3
3 11.07 SELE ICAM1
4 11.01 IL13 ICAM1
5 10.91 SELE ICAM1
6 10.72 SELE ICAM1
7 10.71 SELE IL13 ICAM1

GO Terms for Diabetic Peripheral Angiopathy

Cellular components related to Diabetic Peripheral Angiopathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 collagen-containing extracellular matrix GO:0062023 9.13 ICAM1 FBLN5 F3
2 extracellular space GO:0005615 9.02 SELE IL13 ICAM1 FBLN5 F3

Biological processes related to Diabetic Peripheral Angiopathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.33 IL13 ICAM1 F3
2 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 9.32 SELE ICAM1
3 negative regulation of endothelial cell apoptotic process GO:2000352 9.26 IL13 ICAM1
4 leukocyte cell-cell adhesion GO:0007159 8.96 SELE ICAM1
5 response to lipopolysaccharide GO:0032496 8.92 SELE IL13 ICAM1 CYP27B1

Sources for Diabetic Peripheral Angiopathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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