MCID: DRR001
MIFTS: 58

Diarrhea

Categories: Gastrointestinal diseases, Genetic diseases, Oral diseases, Rare diseases

Aliases & Classifications for Diarrhea

MalaCards integrated aliases for Diarrhea:

Name: Diarrhea 12 30 6 44 45 15 41
Diarrhoea 12 15
Diarrhea of Presumed Infectious Origin 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13250
ICD9CM 36 009.2
MeSH 45 D003967
SNOMED-CT 69 19213003
UMLS 74 C0013369

Summaries for Diarrhea

MedlinePlus : 44 What is diarrhea? Diarrhea is loose, watery stools (bowel movements). You have diarrhea if you have loose stools three or more times in one day. Acute diarrhea is diarrhea that lasts a short time. It is a common problem. It usually lasts about one or two days, but it may last longer. Then it goes away on its own. Diarrhea lasting more than a few days may be a sign of a more serious problem. Chronic diarrhea -- diarrhea that lasts at least four weeks -- can be a symptom of a chronic disease. Chronic diarrhea symptoms may be continual, or they may come and go. What causes diarrhea? The most common causes of diarrhea include Bacteria from contaminated food or water Viruses such as the flu, norovirus, or rotavirus . Rotavirus is the most common cause of acute diarrhea in children. Parasites, which are tiny organisms found in contaminated food or water Medicines such as antibiotics, cancer drugs, and antacids that contain magnesium Food intolerances and sensitivities, which are problems digesting certain ingredients or foods. An example is lactose intolerance. Diseases that affect the stomach, small intestine, or colon, such as Crohn's disease Problems with how the colon functions, such as irritable bowel syndrome Some people also get diarrhea after stomach surgery, because sometimes the surgeries can cause food to move through your digestive system more quickly. Sometimes no cause can be found. If your diarrhea goes away within a few days, finding the cause is usually not necessary. Who is at risk for diarrhea? People of all ages can get diarrhea. On average, adults In the United States have acute diarrhea once a year. Young children have it an average of twice a year. People who visit developing countries are at risk for traveler's diarrhea. It is caused by consuming contaminated food or water. What other symptoms might I have with diarrhea? Other possible symptoms of diarrhea include Cramps or pain in the abdomen An urgent need to use the bathroom Loss of bowel control If a virus or bacteria is the cause of your diarrhea, you may also have a fever, chills, and bloody stools. Diarrhea can cause dehydration, which means that your body does not have enough fluid to work properly. Dehydration can be serious, especially for children, older adults, and people with weakened immune systems. When should I see a doctor for diarrhea? Although it is usually not harmful, diarrhea can become dangerous or signal a more serious problem. Contact your health care provider if you have Signs of dehydration Diarrhea for more than 2 days, if you are an adult. For children, contact the provider if it lasts more than 24 hours. Severe pain in your abdomen or rectum (for adults) A fever of 102 degrees or higher Stools containing blood or pus Stools that are black and tarry If children have diarrhea, parents or caregivers should not hesitate to call a health care provider. Diarrhea can be especially dangerous in newborns and infants. How is the cause of diarrhea diagnosed? To find the cause of diarrhea, your health care provider may Do a physical exam Ask about any medicines you are taking Test your stool or blood to look for bacteria, parasites, or other signs of disease or infection Ask you to stop eating certain foods to see whether your diarrhea goes away If you have chronic diarrhea, your health care provider may perform other tests to look for signs of disease. What are the treatments for diarrhea? Diarrhea is treated by replacing lost fluids and electrolytes to prevent dehydration. Depending on the cause of the problem, you may need medicines to stop the diarrhea or treat an infection. Adults with diarrhea should drink water, fruit juices, sports drinks, sodas without caffeine, and salty broths. As your symptoms improve, you can eat soft, bland food. Children with diarrhea should be given oral rehydration solutions to replace lost fluids and electrolytes. Can diarrhea be prevented? Two types of diarrhea can be prevented - rotavirus diarrhea and traveler's diarrhea. There are vaccines for rotavirus. They are given to babies in two or three doses. You can help prevent traveler's diarrhea by being careful about what you eat and drink when you are in developing countries: Use only bottled or purified water for drinking, making ice cubes, and brushing your teeth If you do use tap water, boil it or use iodine tablets Make sure that the cooked food you eat is fully cooked and served hot Avoid unwashed or unpeeled raw fruits and vegetables NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Diarrhea, also known as diarrhoea, is related to diarrhea 1, secretory chloride, congenital and diarrhea 8, secretory sodium, congenital. An important gene associated with Diarrhea is WNT2B (Wnt Family Member 2B), and among its related pathways/superpathways is Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Ceftriaxone and Atorvastatin have been mentioned in the context of this disorder. Affiliated tissues include lung, breast and colon, and related phenotypes are digestive/alimentary and homeostasis/metabolism

Disease Ontology : 12 A gastrointestinal system disease described as the condition of having frequent loose or liquid bowel movements. Acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. The loss of fluids through diarrhea can cause severe dehydration which is one cause of death in diarrhea sufferers. Along with water, sufferers also lose dangerous amounts of important salts, electrolytes, and other nutrients. There are at least four types of diarrhea

Wikipedia : 77 Diarrhea, also spelled diarrhoea, is the condition of having at least three loose, liquid, or watery... more...

Related Diseases for Diarrhea

Diseases in the Diarrhea family:

Diarrhea 6 Diarrhea 9
Chronic Diarrhea Due to Guanylate Cyclase 2c Overactivity Inflammatory Diarrhea
Acute Diarrhea Congenital Diarrhea

Diseases related to Diarrhea via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 804)
# Related Disease Score Top Affiliating Genes
1 diarrhea 1, secretory chloride, congenital 34.5 SLC26A3 SLC9A3
2 diarrhea 8, secretory sodium, congenital 34.4 SLC9A3 SPINT2
3 diarrhea 2, with microvillus atrophy 34.2 MYO5B SKIV2L SLC26A3 SLC9A3 TTC37
4 diarrhea 5, with tufting enteropathy, congenital 34.2 EPCAM MYO5B NEUROG3 SPINT2
5 trichohepatoenteric syndrome 1 34.0 SKIV2L TTC37
6 secretory diarrhea 33.8 FOXP3 GUCY2C MYO5B SLC26A3 SLC9A3 SPINT2
7 congenital diarrhea 33.6 DGAT1 EPCAM MYO5B NEUROG3 SKIV2L SLC9A3
8 cryptosporidiosis 32.5 CD40LG SST
9 pancreatic cholera 32.3 CCK SST
10 pancreatitis 32.0 CCK SST TMPRSS15
11 steatorrhea 30.6 CCK SST TMPRSS15
12 acute pancreatitis 30.0 CCK SST TMPRSS15
13 paralytic ileus 30.0 CCK SLC26A3
14 duodenal gastrinoma 30.0 CCK SST
15 gastrointestinal system disease 29.8 CCK FOXP3 SST
16 diarrhea 3, secretory sodium, congenital, with or without other congenital anomalies 12.5
17 diarrhea 4, malabsorptive, congenital 12.5
18 congenital chloride diarrhea 12.5
19 diarrhea 6 12.5
20 acute diarrhea 12.5
21 diarrhea 9 12.4
22 chronic diarrhea due to guanylate cyclase 2c overactivity 12.4
23 osmotic diarrhea 12.4
24 inflammatory diarrhea 12.3
25 congenital diarrhea 7 with exudative enteropathy 12.3
26 diarrhea 10, protein-losing enteropathy type 12.3
27 diarrhea 7, protein-losing enteropathy type 12.2
28 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 12.2
29 functional diarrhea 12.2
30 motility-related diarrhea 12.2
31 dysentery 12.0
32 diarrhea, chronic, with villous atrophy 12.0
33 secretory diarrhea, myopathy, and deafness 12.0
34 diarrhea, glucose-stimulated secretory, with common variable immunodeficiency 12.0
35 intractable diarrhea-choanal atresia-eye anomalies syndrome 12.0
36 chronic diarrhea due to glucoamylase deficiency 12.0
37 hemolytic uremic syndrome, atypical 1 11.9
38 satoyoshi syndrome 11.8
39 wdha syndrome 11.8
40 vipoma 11.8
41 cholera 11.6
42 irritable bowel syndrome 11.5
43 hemolytic uremic syndrome, atypical 2 11.5
44 hemolytic uremic syndrome, atypical 3 11.5
45 hemolytic uremic syndrome, atypical 4 11.5
46 hemolytic uremic syndrome, atypical 5 11.5
47 hemolytic uremic syndrome, atypical 6 11.5
48 gastroenteritis 11.4
49 shigellosis 11.4
50 hemolytic-uremic syndrome 11.4

Graphical network of the top 20 diseases related to Diarrhea:



Diseases related to Diarrhea

Symptoms & Phenotypes for Diarrhea

MGI Mouse Phenotypes related to Diarrhea:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.91 DGAT1 EPCAM FOXP3 GUCY2C MYO5B NEUROG3
2 homeostasis/metabolism MP:0005376 9.77 CCK CD40LG DGAT1 EPCAM FOXP3 GUCY2C
3 endocrine/exocrine gland MP:0005379 9.76 CCK CD40LG DGAT1 EPCAM FOXP3 NEUROG3
4 no phenotypic analysis MP:0003012 9.17 ANTXR2 CCK EPCAM FOXP3 NEUROG3 SST

Drugs & Therapeutics for Diarrhea

Drugs for Diarrhea (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1343)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ceftriaxone Approved Phase 4,Phase 2,Not Applicable 73384-59-5 5479530 5361919
2
Atorvastatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 134523-00-5 60823
3
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 3,Phase 1 9004-61-9 53477741
4
Diclofenac Approved, Vet_approved Phase 4,Not Applicable 15307-86-5 3033
5
Dexmedetomidine Approved, Vet_approved Phase 4,Not Applicable 113775-47-6 5311068 68602
6
Carboprost tromethamine Approved Phase 4 58551-69-2 35023177 5284525
7
Glyburide Approved Phase 4,Phase 3 10238-21-8 3488
8
Glucagon Approved Phase 4,Phase 1,Phase 2,Not Applicable 16941-32-5
9 Pinaverium Approved Phase 4,Not Applicable 59995-65-2
10
Copper Approved, Investigational Phase 4,Not Applicable 7440-50-8 27099
11
Zinc Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 7440-66-6 32051
12
leucovorin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 58-05-9 143 6006
13
Tocopherol Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 1406-66-2 14986
14
Iron Approved, Experimental Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 7439-89-6, 15438-31-0 27284 23925
15
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 73590-58-6 4594
16
Diltiazem Approved, Investigational Phase 4 42399-41-7 39186
17
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 93-14-1 3516
18
Methadone Approved, Illicit Phase 4,Phase 3 76-99-3 4095
19
Metformin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 657-24-9 14219 4091
20
Exenatide Approved, Investigational Phase 4,Phase 2,Phase 3 141758-74-9 15991534
21
Insulin glargine Approved Phase 4,Phase 3,Phase 1 160337-95-1
22
Insulin Lispro Approved Phase 4,Phase 3,Phase 2 133107-64-9
23
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 50-78-2 2244
24
Ticlopidine Approved Phase 4 55142-85-3 5472
25
Clopidogrel Approved Phase 4 120202-66-6, 113665-84-2 60606
26
Donepezil Approved Phase 4,Phase 3,Phase 2,Not Applicable 120014-06-4 3152
27
Acetylcholine Approved, Investigational Phase 4,Phase 2,Not Applicable 51-84-3 187
28
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1 26787-78-0 33613
29 Strawberry Approved Phase 4,Phase 3,Phase 2,Not Applicable
30
Bisoprolol Approved Phase 4 66722-44-9 2405
31
Ferrous fumarate Approved Phase 4,Phase 3,Not Applicable 141-01-5
32
lanreotide Approved Phase 4,Phase 2,Phase 3 108736-35-2
33
Somatostatin Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 38916-34-6, 51110-01-1 53481605
34
Pasireotide Approved Phase 4,Phase 3,Phase 2 396091-73-9 9941444
35
Octreotide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 83150-76-9 6400441 383414
36
Alendronate Approved Phase 4 66376-36-1, 121268-17-5 2088
37
Norepinephrine Approved Phase 4,Phase 3 51-41-2 439260
38
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
39
Acetylcysteine Approved, Investigational Phase 4,Phase 2 616-91-1 12035
40
Cisplatin Approved Phase 4,Phase 2,Phase 3,Phase 1 15663-27-1 2767 441203 84093
41
Tranexamic Acid Approved Phase 4,Phase 3,Not Applicable 1197-18-8 5526
42
Metronidazole Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 443-48-1 4173
43
Mifepristone Approved, Investigational Phase 4,Not Applicable 84371-65-3 55245
44
Misoprostol Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 59122-46-2 5282381
45
Naproxen Approved, Vet_approved Phase 4,Not Applicable 22204-53-1 156391 1302
46
Esomeprazole Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 161796-78-7, 161973-10-0, 119141-88-7 9568614 4594
47
Celecoxib Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 169590-42-5 2662
48
Ethanol Approved Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 64-17-5 702
49
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 3 16590-41-3 5360515
50
Loperamide Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 53179-11-6 3955

Interventional clinical trials:

(show top 50) (show all 3672)
# Name Status NCT ID Phase Drugs
1 Lactobacillus Preparation on the Incidence of Diarrhea Unknown status NCT01792739 Phase 4 Lactobacillus casei variety rhamnosus granules;Placebo
2 Bacillus Particles Prevent Children Antibiotics Associated Diarrhea Unknown status NCT02993419 Phase 4 Bacillus licheniformis Intervention
3 Heweizhixie capsuleTherapy on Patients With Diarrhea Unknown status NCT02607176 Phase 4 Heweizhixie capsule
4 Saccharomyces Boulardii in Diarrhea Dominant Irritable Bowel Syndrome Unknown status NCT00543478 Phase 4 Saccharomyces boulardii;Methyl cellulose powder (low viscosity)
5 Prophylaxis of Gastrointestinal Infections With EcN Unknown status NCT01469273 Phase 4 Mutaflor® Suspension
6 Improving Bowel Habits of Elderly With Probiotics and Non-probiotics Unknown status NCT02949882 Phase 4
7 Lactibiane Tolérance® in Individuals Suffering From Irritable Bowel Syndrome With Diarrheal Predominance Unknown status NCT02728063 Phase 4
8 The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis Unknown status NCT01278017 Phase 4 ceftriaxone
9 Anti-inflammatory Effect of Atorvastatin in Atherosclerotic Plaques Assessed by FDG-PET Imaging Unknown status NCT00920101 Phase 4 Atorvastatin
10 Clinical Study of Artz in the Treatment of Knee Osteoarthritis Unknown status NCT02826031 Phase 4 Sodium Hyaluronate Injection;DICL-SR
11 Dexmedetomidine on Prevention of Side Effects of Hemabate Unknown status NCT02220361 Phase 4 placebo;low dose dexmedetomidine;high dose dexmedetomidine
12 Long-Term Sulfonylurea Response in ABCC8 Neonatal Diabetes (SuResponsSUR) Unknown status NCT02624830 Phase 4 Sulfonylurea
13 Pinaverium Bromide in Post-cholecystectomy Sphincter of Oddi Dysfunction Unknown status NCT02833103 Phase 4 Danshu Capsules;Pinaverium Bromide
14 The Effect of Probiotics on Exacerbation of Inflammatory Bowel Disease Exacerbation (Crohn's Disease) Unknown status NCT01765998 Phase 4 Probiotic;Placebo
15 Comparison of Enteral Versus Intravenous Potassium Supplementation Unknown status NCT02015962 Phase 4 Intravenous potassium chloride;Oral potassium chloride
16 Effect of Ramosetron on Bowel Motility After Colorectal Resection Unknown status NCT01427127 Phase 4 Ramosetron
17 Strategy to Improve Adherence of Roflumilast Unknown status NCT02018432 Phase 4 Roflumilast escalation dosage;Roflumilast conventional dosage
18 Trial of Captafer® vs. Oral Iron Sulfate in the Treatment of Iron Deficiency Anemia in Patients With IBD Unknown status NCT02774057 Phase 4 Captafer®;Iron Sulfate
19 Randomized, Double Blind, Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease (GERD) Unknown status NCT01822106 Phase 4
20 Pediatrics Anal Fissures Treatment With Polyethylene Glycol Unknown status NCT02419534 Phase 4 Polyethylene glycol;Polyethylene glycol with Diltiazem
21 Adjunct Methadone to Decrease the Duration of Mechanical Ventilation in the Medical Intensive Care Unit Unknown status NCT02025855 Phase 4 Methadone;Placebo
22 Manipulation of Visceral Sensitivity and Immune System in IBS Unknown status NCT00418340 Phase 4 probiotic (bacterial/dietary supplement)
23 Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remission Unknown status NCT01901666 Phase 4 Growth Hormone
24 Metformin for Weight Control in Adolescents Taking Atypical Antipsychotics Unknown status NCT00845936 Phase 4 Metformin
25 Effect of Exenatide on 24h-UAER in Patients With Diabetic Nephropathy Unknown status NCT02690883 Phase 4 Exenatide;Lispro
26 Safety Study of Enterovirus 71 Vaccine in Children Aged 6-35 Months Old Unknown status NCT02806531 Phase 4
27 The Efficacy of Hydrolyzed Guar Gum ( PHGG) in the Treatment of Patients With Irritable Bowel Syndrome (IBS) Unknown status NCT01779765 Phase 4
28 Medical and Endovascular Treatment of Atherosclerotic Renal Artery Stenosis (METRAS Study) Unknown status NCT01208714 Phase 4 Optimal medical therapy
29 Treatment With Acetyl-Choline Esterase Inhibitors in Children With Autism Spectrum Disorders Unknown status NCT01098383 Phase 4 Acetyl-Choline Esterase Inhibitors and Choline supplements;Indistinguishable placebo tablets, matching both donepezil and choline
30 Middle Meatal Bacteriology During Acute Respiratory Infection in Children Unknown status NCT00545961 Phase 4 placebo;amoxicillin clavulanate acid
31 BRAVE Study With Uncontrolled Essential Hypertension (BRAVE Study) Unknown status NCT02398929 Phase 4 Bisoprolol 2.5 mg;Placebo
32 The Use of Iron Therapy for Patients With Anemia After Surgery Unknown status NCT01975272 Phase 4 Ferinject;Ferrous fumarate;Placebo for ferrous fumarate;Placebo for ferinject
33 Pasireotide LAR and Pegvisomant Study in Acromegaly Unknown status NCT02668172 Phase 4 Pasireotide LAR 60 mg;Pegvisomant
34 Efficacy and Safety of Brand Versus Generic Alendronate for Osteoporosis Treatment Unknown status NCT02371252 Phase 4 Generic alendronate
35 Neurochemical, Metabonomics and Neuroimaging Characterization of TCM Diagnostic Subtypes of Major Depression Disorder Unknown status NCT02346682 Phase 4 venlafaxine
36 THE USE OF N-ACETYLCYSTEINE ATTENUATING CISPLATIN-INDUCED TOXICITIES BY OXIDATIVE STRESS Unknown status NCT02241876 Phase 4 N-acetylcysteine
37 Tranexamic Acid for Bleeding in Breast Surgery Unknown status NCT02615366 Phase 4 Tranexamic Acid;Placebo
38 Dose and Duration of Metronidazole and Amoxicillin for Treatment of Chronic Periodontitis Unknown status NCT02735395 Phase 4 Metronidazole 250 (7 days);Metronidazole 400 (7 days);Metronidazole 250 (14 days);Metronidazole 400 (14 days);Amoxicillin
39 Probiotics in Newly Recognized Type 1 Diabetes Unknown status NCT03032354 Phase 4 Lactobacillus rhamnosus GG and Bifidobacterium lactis BB12
40 Medical Abortion at Gestational Age of 8 to ≤9 Weeks Versus >9 to ≤12 Weeks Unknown status NCT02745093 Phase 4 Mifepristone;Misoprostol
41 Duration of Antibiotic Therapy in Community - Acquired Pneumonia Unknown status NCT01492387 Phase 4
42 Gastro-protective Effect and Pain Relief Effect of Naxozol Compared to Celecoxib in Patients With Osteoarthritis Unknown status NCT02355236 Phase 4 Naproxen/Esomeprazol 500/20mg;Celecoxib 200mg;Naxozol-Placebo;Comparator-Placebo
43 Pain Relief In Irritable Bowel Syndrome Unknown status NCT02573844 Phase 4 Proklama
44 Low Dose Naltrexone for Treatment of Pain in Patients With Fibromyalgia - Effect Via a Central Mechanism? Unknown status NCT02806440 Phase 4 Low dose naltrexone;Placebo
45 Effects of Probiotics and/or Prebiotics on the Duration of Diarrhea and Hospitalization in Children Completed NCT01927094 Phase 4
46 Community Based Intervention and Evaluation of the Impact of Social Marketing of a Diarrhea Management Pack Completed NCT00942812 Phase 4
47 Lactobacillus Reuteri DSM 17938 in the Prevention of Antibiotic-associated Diarrhea in Children: Protocol of a Randomized Controlled Trial Completed NCT02871908 Phase 4 Lactobacillus reuteri DSM 17938;Placebo
48 Oral Administration of Tannins and Flavonoids in Children With Acute Diarrhea Completed NCT03356327 Phase 4 Actitan F;Standard Oral Rehydration
49 Use of Probiotic Yogurt in the Treatment of Acute Diarrhea in Children Completed NCT01564290 Phase 4 Placebo probiotic
50 Efficacy of Lactobacillus GG With Diosmectite in Treatment Children With Acute Gastroenteritis Completed NCT01657032 Phase 4

Search NIH Clinical Center for Diarrhea

Cochrane evidence based reviews: diarrhea

Genetic Tests for Diarrhea

Genetic tests related to Diarrhea:

# Genetic test Affiliating Genes
1 Diarrhea 30

Anatomical Context for Diarrhea

MalaCards organs/tissues related to Diarrhea:

42
Lung, Breast, Colon, Testes, Kidney, Prostate, T Cells

Publications for Diarrhea

Articles related to Diarrhea:

(show top 50) (show all 8269)
# Title Authors Year
1
Effect of Zinc Supplementation on the Frequency and Consistency of Stool in Children with Acute Diarrhea. ( 31106100 )
2019
2
Molecular Detection and Epidemiological Features of Selected Bacterial, Viral, and Parasitic Enteropathogens in Stool Specimens from Children with Acute Diarrhea in Thi-Qar Governorate, Iraq. ( 31064051 )
2019
3
Molecular epidemiology and genetic diversity of human parechoviruses in children hospitalized with acute diarrhea in Thailand during 2011-2016. ( 30972593 )
2019
4
Hemorrhagic Fever with Renal Syndrome as a Cause of Acute Diarrhea. ( 30915955 )
2019
5
Genetic investigation confirmed the clinical phenotype of congenital chloride diarrhea in a Hungarian patient: a case report. ( 30635044 )
2019
6
Efficacy of an orally administered anti-diarrheal probiotic paste (Pro-Kolin Advanced) in dogs with acute diarrhea: A randomized, placebo-controlled, double-blinded clinical study. ( 30882953 )
2019
7
Plasma citrulline, arginine, nitric oxide, and blood ammonia levels in neonatal calves with acute diarrhea. ( 30788867 )
2019
8
Outcomes and clinical relevance of stool multiplex bacterial polymerase chain reaction in patients with acute diarrhea: single center experience. ( 30685964 )
2019
9
Efficacy of gelatin tannate for acute diarrhea in children: a systematic review and meta-analysis. ( 30465439 )
2019
10
Ultrasound Adds No Benefit to Clinical Exam for Predicting Dehydration in Children With Acute Diarrhea in a Resource-Limited Setting. ( 30291639 )
2019
11
A prospective, interventional, randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy and safety of Bacillus coagulans LBSC in the treatment of acute diarrhea with abdominal discomfort. ( 30264164 )
2019
12
Prevalence of rotavirus and rapid changes in circulating rotavirus strains among children with acute diarrhea in China, 2009-2015. ( 30017609 )
2019
13
Complete Genome Sequence of Variant Porcine Epidemic Diarrhea Virus Strain ZJ/ZX2018-C10, Isolated in Zhejiang, China, in 2018. ( 30938695 )
2019
14
Association of meteorological factors with infectious diarrhea incidence in Guangzhou, southern China: A time-series study (2006-2017). ( 30954825 )
2019
15
Associations between High Temperature, Heavy Rainfall, and Diarrhea among Young Children in Rural Tamil Nadu, India: A Prospective Cohort Study. ( 30986088 )
2019
16
Comparison of the systemic phospholipid profile in dogs diagnosed with idiopathic inflammatory bowel disease or food-responsive diarrhea before and after treatment. ( 30990833 )
2019
17
Diarrhea, Dehydration, and the Associated Mortality in Children with Complicated Severe Acute Malnutrition: A Prospective Cohort Study in Uganda. ( 30992218 )
2019
18
Diagnosing and tracing the pathogens of infantile infectious diarrhea by amplicon sequencing. ( 30992716 )
2019
19
A TaqMan probe-based real-time PCR to differentiate porcine epidemic diarrhea virus virulent strains from attenuated vaccine strains. ( 31004698 )
2019
20
EAST1 toxin: An enigmatic molecule associated with sporadic episodes of diarrhea in humans and animals. ( 31016564 )
2019
21
The place of tachykinin NK2 receptor antagonists in the treatment diarrhea-predominant irritable bowel syndrome. ( 31019119 )
2019
22
The curse of dimensionality: Animal-related risk factors for pediatric diarrhea in western Kenya, and methods for dealing with a large number of predictors. ( 31026290 )
2019
23
Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signalling pathways. ( 31030832 )
2019
24
Chapparvovirus DNA Found in 4% of Dogs with Diarrhea. ( 31035625 )
2019
25
Probiotics for the prevention of pediatric antibiotic-associated diarrhea. ( 31039287 )
2019
26
Diarrhea caused by Shigella flexneri in patients with primary HIV infection. ( 31046618 )
2019
27
Diagnosis of Yersinia enterocolitica Infection in Cancer Patients With Diarrhea in the Era of Molecular Diagnostics for Gastrointestinal Infections. ( 31049362 )
2019
28
A Granular Approach to a Patient with Diarrhea and Flushing. ( 31111279 )
2019
29
Identifying outbreaks of Porcine Epidemic Diarrhea virus through animal movements and spatial neighborhoods. ( 30679594 )
2019
30
Risk Factors for Undernutrition and Diarrhea Prevalence in an Urban Slum in Indonesia: Focus on Water, Sanitation, and Hygiene. ( 30693865 )
2019
31
Progress in the use of ORS and zinc for the treatment of childhood diarrhea. ( 30701067 )
2019
32
New Tools to Test Stool: Managing Travelers' Diarrhea in the Era of Molecular Diagnostics. ( 30712762 )
2019
33
Real-time analysis of quantum dot labeled single porcine epidemic diarrhea virus moving along the microtubules using single particle tracking. ( 30718724 )
2019
34
An unusual cause of chronic diarrhea: plastron appendicitis. ( 30949323 )
2019
35
Monomorphic Epitheliotropic Intestinal T cell Lymphoma: a Rare Cause of Chronic Diarrhea. ( 30761475 )
2019
36
Diagnosis and Management of Infectious Diarrhea. ( 30763429 )
2019
37
G1P[8] Rotavirus in children with severe diarrhea in the post-vaccine introduction era in Brazil: Evidence of reassortments and structural modifications of the antigenic VP7 and VP4 regions. ( 30763774 )
2019
38
Diarrhea with epidermal growth factor receptor tyrosine kinase inhibitors in cancer patients: A meta-analysis of randomized controlled trials. ( 30771871 )
2019
39
Risk factors for acute childhood diarrhea: A cross-sectional study comparing refugee camps and host communities in Gambella Region, Ethiopia. ( 30772602 )
2019
40
A Randomized, Placebo-controlled Trial of Fidaxomicin for Prophylaxis of Clostridium difficile-associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation. ( 30772906 )
2019
41
Porcine epidemic diarrhea virus in Asia: An alarming threat to the global pig industry. ( 30779958 )
2019
42
Tumor suppressor p53 inhibits porcine epidemic diarrhea virus infection via interferon-mediated antiviral immunity. ( 30784764 )
2019
43
Case 6-2019: A 29-Year-Old Woman with Nausea, Vomiting, and Diarrhea. ( 30786192 )
2019
44
Refractory Infantile Chronic Diarrhea and Failure to Thrive in a 6-Month-Old Boy With a Complex Past Medical History. ( 30788983 )
2019
45
Targeting the Viral Polymerase of Diarrhea-Causing Viruses as a Strategy to Develop a Single Broad-Spectrum Antiviral Therapy. ( 30791582 )
2019
46
Genome analysis of a G9P[23] group A rotavirus isolated from a dog with diarrhea in China. ( 30796978 )
2019
47
Smectite for Acute Infectious Diarrhea in Children. ( 30811159 )
2019
48
Bovine colostrum and product intervention associated with relief of childhood infectious diarrhea. ( 30816291 )
2019
49
Assessment of the cost effectiveness of compulsory testing of introduced animals and bulk tank milk testing for bovine viral diarrhea in Japan. ( 30828031 )
2019
50
Value-based Pricing for Rifaximin Increases Access of Patients With Irritable Bowel Syndrome With Diarrhea to Therapy. ( 30831219 )
2019

Variations for Diarrhea

ClinVar genetic disease variations for Diarrhea:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 WNT2B NM_024494.2(WNT2B): c.205C> T (p.Arg69Ter) single nucleotide variant Pathogenic rs370244148 GRCh38 Chromosome 1, 112514896: 112514896
2 WNT2B NM_024494.2(WNT2B): c.205C> T (p.Arg69Ter) single nucleotide variant Pathogenic rs370244148 GRCh37 Chromosome 1, 113057518: 113057518

Expression for Diarrhea

Search GEO for disease gene expression data for Diarrhea.

Pathways for Diarrhea

Pathways related to Diarrhea according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.92 EPCAM NEUROG3 WNT2B

GO Terms for Diarrhea

Cellular components related to Diarrhea according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 apical plasma membrane GO:0016324 9.46 EPCAM SI SLC26A3 SLC9A3
2 Ski complex GO:0055087 8.96 SKIV2L TTC37
3 brush border GO:0005903 8.92 MME SI SLC9A3 TMPRSS15
4 integral component of membrane GO:0016021 10.03 ANTXR2 CD40LG CYP3A4 DGAT1 EPCAM GUCY2C

Biological processes related to Diarrhea according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA catabolic process GO:0006401 9.16 SKIV2L TTC37
2 positive regulation of interleukin-4 production GO:0032753 8.96 CD40LG FOXP3
3 digestion GO:0007586 8.8 CCK GUCY2C SST

Sources for Diarrhea

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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