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MCID: DRR009
MIFTS: 23
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Diarrhea 6
Categories:
Genetic diseases, Gastrointestinal diseases, Rare diseases
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MalaCards integrated aliases for Diarrhea 6:
Characteristics:Orphanet epidemiological data:59
chronic diarrhea due to guanylate cyclase 2c overactivity
Inheritance: Autosomal dominant; Prevalence: <1/1000000 (Worldwide); Age of onset: Infancy,Neonatal; HPO:32Classifications:
ICD10:
34
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OMIM
:
57
Diarrhea-6 is a relatively mild, early-onset chronic diarrhea that may be associated with increased susceptibility to inflammatory bowel disease, small bowel obstruction, and esophagitis (Fiskerstrand et al., 2012).
For a discussion of phenotypic and genetic heterogeneity of congenital diarrhea, see DIAR1 (214700). (614616)
MalaCards based summary : Diarrhea 6, also known as diar6, is related to chronic diarrhea due to guanylate cyclase 2c overactivity and dysentery. An important gene associated with Diarrhea 6 is GUCY2C (Guanylate Cyclase 2C). Related phenotypes are diarrhea and abdominal pain UniProtKB/Swiss-Prot : 75 Diarrhea 6: A relatively mild, early-onset chronic diarrhea that may be associated with increased susceptibility to inflammatory bowel disease, small bowel obstruction, and esophagitis. |
Diseases in the Diarrhea family:
Diseases related to Diarrhea 6 via text searches within MalaCards or GeneCards Suite gene sharing:
Graphical network of the top 20 diseases related to Diarrhea 6:
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Symptoms via clinical synopsis from OMIM:57Clinical features from OMIM:614616Human phenotypes related to Diarrhea 6:32
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Articles related to Diarrhea 6:
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Genes related to Diarrhea 6 (1 elite genes):
- Elite gene
- Cancer Census gene in COSMIC
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UniProtKB/Swiss-Prot genetic disease variations for Diarrhea 6:75
ClinVar genetic disease variations for Diarrhea 6:6
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