MCID: DNT004
MIFTS: 22

Dientamoebiasis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Dientamoebiasis

MalaCards integrated aliases for Dientamoebiasis:

Name: Dientamoebiasis 12 44 15 70
Intestinal Trichomoniasis 12 70

Classifications:



External Ids:

Disease Ontology 12 DOID:946
MeSH 44 D004030
UMLS 70 C0012147 C0411268

Summaries for Dientamoebiasis

Disease Ontology : 12 A parasitic protozoa infectious disease that involves infection of the large intestine by a protozoan parasite Dientamoeba fragilis. The symptoms include diarrhea, stomach pain and cramping, loss of appetite and weight, nausea, and fatigue.

MalaCards based summary : Dientamoebiasis, also known as intestinal trichomoniasis, is related to trichomoniasis and anisakiasis. An important gene associated with Dientamoebiasis is MAPKAPK5 (MAPK Activated Protein Kinase 5), and among its related pathways/superpathways is MAPK signaling pathway. The drugs Metronidazole and Antiparasitic Agents have been mentioned in the context of this disorder.

Wikipedia : 73 Dientamoebiasis is a medical condition caused by infection with Dientamoeba fragilis, a single-cell... more...

Related Diseases for Dientamoebiasis

Diseases related to Dientamoebiasis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 trichomoniasis 10.5
2 anisakiasis 10.0
3 diarrhea 9.9
4 rhinitis 9.9
5 tracheitis 9.9
6 noonan syndrome 1 9.4 MT-CO1 MAPKAPK5

Graphical network of the top 20 diseases related to Dientamoebiasis:



Diseases related to Dientamoebiasis

Symptoms & Phenotypes for Dientamoebiasis

Drugs & Therapeutics for Dientamoebiasis

Drugs for Dientamoebiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metronidazole Approved Phase 4 443-48-1 4173
2 Antiparasitic Agents Phase 4
3 Anti-Bacterial Agents Phase 4
4 Anti-Infective Agents Phase 4
5 Antiprotozoal Agents Phase 4
6
Formaldehyde Approved, Vet_approved 50-00-0 712
7 Ether
8 Disinfectants

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Metronidazole for the Treatment of Dientamoebiasis in Children in Denmark - A Randomized, Placebo-controlled, Double-blinded Clinical Trial Completed NCT01314976 Phase 4 Metronidazole;Placebo
2 Diagnosis of Neglected Tropical Diseases (NTDs) in Patients Presenting With Persistent Digestive Disorders (≥2 Weeks) in Côte d'Ivoire, Indonesia, Mali and Nepal Completed NCT02105714

Search NIH Clinical Center for Dientamoebiasis

Cochrane evidence based reviews: dientamoebiasis

Genetic Tests for Dientamoebiasis

Anatomical Context for Dientamoebiasis

Publications for Dientamoebiasis

Articles related to Dientamoebiasis:

(show all 41)
# Title Authors PMID Year
1
Dientamoeba fragilis - the most common intestinal protozoan in the Helsinki Metropolitan Area, Finland, 2007 to 2017. 61
31339096 2019
2
The importance of considering the neglected intestinal protozoan parasite Dientamoeba fragilis. 61
31050625 2019
3
MALDI-TOF MS as a new tool for the identification of Dientamoeba fragilis. 61
29301570 2018
4
Report of the first clinical case of intestinal trichomoniasis caused by Tritrichomonas foetus in a cat with chronic diarrhoea in Brazil. 61
28412947 2017
5
Dientamoeba fragilis, One of the Neglected Intestinal Protozoa. 61
27053676 2016
6
Dientamoeba fragilis, the Neglected Trichomonad of the Human Bowel. 61
27170141 2016
7
Metronidazole therapy for treating dientamoebiasis in children is not associated with better clinical outcomes: a randomized, double-blinded and placebo-controlled clinical trial. 61
24647023 2014
8
Activity of benzimidazoles against Dientamoeba fragilis (Trichomonadida, Monocercomonadidae) in vitro and correlation of beta-tubulin sequences as an indicator of resistance. 61
25148459 2014
9
Anisakiasis mistaken for dientamoebiasis? 61
23965282 2013
10
Cyst formation and faecal-oral transmission of Dientamoeba fragilis--the missing link in the life cycle of an emerging pathogen. 61
23872523 2013
11
A new species of Tritrichomonas (Sarcomastigophora: Trichomonida) from the domestic cat (Felis catus). 61
23525691 2013
12
Current treatment options for Dientamoeba fragilis infections. 61
24533282 2012
13
Survival of a feline isolate of Tritrichomonas foetus in water, cat urine, cat food and cat litter. 61
22100399 2012
14
A case-controlled study of Dientamoeba fragilis infections in children. 61
21524324 2011
15
Newly defined conditions for the in vitro cultivation and cryopreservation of Dientamoeba fragilis: new techniques set to fast track molecular studies on this organism. 61
20609278 2010
16
First report of feline intestinal trichomoniasis caused by Tritrichomonas foetus in Korea. 61
20877505 2010
17
Fluorescence in situ hybridization for identification of Tritrichomonas foetus in formalin-fixed and paraffin-embedded histological specimens of intestinal trichomoniasis. 61
20447769 2010
18
Evaluation of a real-time polymerase chain reaction assay for the detection of Dientamoeba fragilis. 61
20462728 2010
19
A review of the clinical presentation of dientamoebiasis. 61
20348509 2010
20
A comparison of metronidazole and single-dose ornidazole for the treatment of dientamoebiasis. 61
18397330 2008
21
Prevalence and clinical features of Dientamoeba fragilis infections in patients suspected to have intestinal parasitic infection. 61
17985591 2007
22
Dientamoeba fragilis in swine population: a preliminary investigation. 61
17314011 2007
23
[Role of Dientamoeba fragilis in human bowel infections]. 61
17515673 2007
24
[Human intestinal parasitosis: role of Dientamoeba fragilis in human infections]. 61
17405510 2007
25
Irritable bowel syndrome: a review on the role of intestinal protozoa and the importance of their detection and diagnosis. 61
17070814 2007
26
Clinical and microbiological features of dientamoebiasis in patients suspected of suffering from a parasitic gastrointestinal illness: a comparison of Dientamoeba fragilis and Giardia lamblia infections. 61
16469517 2006
27
Dientamoebiasis: clinical importance and recent advances. 61
16380293 2006
28
Dientamoeba fragilis, a neglected cause of diarrhea, successfully treated with secnidazole. 61
12588330 2003
29
[Dientamoeba fragilis and dientamoebiasis: aspects of clinical parasitology and laboratory diagnosis]. 61
11921541 2001
30
Respiratory and intestinal trichomoniasis in mule ducks. 61
18483934 1997
31
Intestinal trichomoniasis due to Tritrichomonas mobilensis in tree shrews (Tupaia belangeri). 61
8569152 1995
32
On the clinical importance of Dientamoeba fragilis infections in childhood. 61
1880405 1991
33
Dientamoeba fragilis infection, a cause of gastrointestinal symptoms in childhood. 61
2325352 1990
34
[Clinical analysis of 253 cases of intestinal trichomoniasis]. 61
6678655 1983
35
Equine intestinal trichomoniasis. 61
4243948 1969
36
Equine protozoan diarrhea (equine intestinal trichomoniasis) at Trinidad racetracks. 61
5812452 1969
37
[Treatment of intestinal trichomoniasis with the new antibiotic aminosidine sulphate]. 61
5595393 1967
38
[Intestinal trichomoniasis associated with acute apendicitis. Presentation of a case]. 61
5294234 1965
39
[Antiparasitic therapeutics. Intestinal trichomoniasis]. 61
13687609 1959
40
[Clinical aspects of intestinal trichomoniasis]. 61
13482787 1957
41
[Case of intestinal trichomoniasis, resistant to typical therapy, cured by paludrine]. 61
14862654 1951

Variations for Dientamoebiasis

Expression for Dientamoebiasis

Search GEO for disease gene expression data for Dientamoebiasis.

Pathways for Dientamoebiasis

Pathways related to Dientamoebiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.29 MAPKAPK5 FGF2

GO Terms for Dientamoebiasis

Biological processes related to Dientamoebiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MAPK cascade GO:0000165 9.16 MAPKAPK5 FGF2
2 activation of MAPK activity GO:0000187 8.96 MAPKAPK5 FGF2
3 Ras protein signal transduction GO:0007265 8.62 MAPKAPK5 FGF2

Sources for Dientamoebiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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