MCID: DFF031
MIFTS: 25

Diffuse Alveolar Hemorrhage

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Diffuse Alveolar Hemorrhage

MalaCards integrated aliases for Diffuse Alveolar Hemorrhage:

Name: Diffuse Alveolar Hemorrhage 60

Characteristics:

Orphanet epidemiological data:

60
diffuse alveolar hemorrhage
Prevalence: 1-9/100000 (Europe);

Classifications:

Orphanet: 60  
Rare respiratory diseases


External Ids:

ICD10 via Orphanet 35 J98.4
Orphanet 60 ORPHA90060

Summaries for Diffuse Alveolar Hemorrhage

MalaCards based summary : Diffuse Alveolar Hemorrhage is related to lupus erythematosus and systemic lupus erythematosus. An important gene associated with Diffuse Alveolar Hemorrhage is CYP2C9 (Cytochrome P450 Family 2 Subfamily C Member 9). Affiliated tissues include lung, bone and bone marrow.

Related Diseases for Diffuse Alveolar Hemorrhage

Diseases related to Diffuse Alveolar Hemorrhage via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 104)
# Related Disease Score Top Affiliating Genes
1 lupus erythematosus 10.7
2 systemic lupus erythematosus 10.6
3 vasculitis 10.5
4 antiphospholipid syndrome 10.3
5 glomerulonephritis 10.3
6 granulomatosis with polyangiitis 10.3
7 respiratory failure 10.3
8 microscopic polyangiitis 10.3
9 acute respiratory distress syndrome 10.2
10 angiosarcoma 10.2
11 endocarditis 10.2
12 pneumonia 10.2
13 rheumatoid arthritis 10.1
14 arthritis 10.1
15 hematopoietic stem cell transplantation 10.1
16 purpura 10.1
17 scleroderma, familial progressive 10.1
18 leukemia 10.1
19 thrombocytopenia 10.1
20 pulmonary edema 10.1
21 leptospirosis 10.1
22 rapidly progressive glomerulonephritis 10.1
23 anca-associated vasculitis 10.1
24 eosinophilic granulomatosis with polyangiitis 10.1
25 autoimmune disease 10.0
26 thrombocytopenic purpura, autoimmune 10.0
27 autoimmune disease 1 10.0
28 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.0
29 legionnaires' disease 10.0
30 acute poststreptococcal glomerulonephritis 10.0
31 pulmonary tuberculosis 10.0
32 churg-strauss syndrome 10.0
33 ischemia 10.0
34 influenza 10.0
35 allergic angiitis 10.0
36 isolated pulmonary capillaritis 10.0
37 spondyloarthropathy 1 9.8
38 breast cancer 9.8
39 cardiac conduction defect 9.8
40 multiple sclerosis 9.8
41 esophageal cancer 9.8
42 renal cell carcinoma, nonpapillary 9.8
43 pheochromocytoma 9.8
44 pulmonary hemosiderosis 9.8
45 down syndrome 9.8
46 hemolytic uremic syndrome, atypical 1 9.8
47 myelofibrosis 9.8
48 myeloma, multiple 9.8
49 pulmonary venoocclusive disease 1, autosomal dominant 9.8
50 sjogren syndrome 9.8

Graphical network of the top 20 diseases related to Diffuse Alveolar Hemorrhage:



Diseases related to Diffuse Alveolar Hemorrhage

Symptoms & Phenotypes for Diffuse Alveolar Hemorrhage

Drugs & Therapeutics for Diffuse Alveolar Hemorrhage

Search Clinical Trials , NIH Clinical Center for Diffuse Alveolar Hemorrhage

Genetic Tests for Diffuse Alveolar Hemorrhage

Anatomical Context for Diffuse Alveolar Hemorrhage

MalaCards organs/tissues related to Diffuse Alveolar Hemorrhage:

42
Lung, Bone, Bone Marrow, Myeloid, T Cells, Neutrophil, B Cells

Publications for Diffuse Alveolar Hemorrhage

Articles related to Diffuse Alveolar Hemorrhage:

(show top 50) (show all 334)
# Title Authors Year
1
Recreational 'mud fever': Leptospira interrogans induced diffuse alveolar hemorrhage and severe acute respiratory distress syndrome in a U.S. Navy seaman following 'mud-run' in Hawaii. ( 30976519 )
2019
2
Diffuse alveolar hemorrhage in a patient with ANCA-associated vasculitis after thyroidectomy: A case report. ( 30813199 )
2019
3
Refractory diffuse alveolar hemorrhage caused by eosinophilic granulomatosis with polyangiitis in the absence of elevated biomarkers treated successfully by rituximab and mepolizumab: A case report. ( 30603598 )
2019
4
A different clinical presentation of Heiner syndrome: The case of diffuse alveolar hemorrhage causing massive hemoptysis and hematemesis. ( 30733916 )
2019
5
Long term veno-venous extracorporeal life support without intravenous anticoagulation for diffuse alveolar hemorrhage. ( 30744494 )
2019
6
Hyaluronic acid-induced diffuse alveolar hemorrhage: unknown complication induced by a well-known injectable agent. ( 30788360 )
2019
7
Diffuse Alveolar Hemorrhage Caused by Warfarin after Rifampicin Discontinuation. ( 30809261 )
2019
8
Diffuse alveolar hemorrhage following sugammadex and remifentanil administration: A case report. ( 30813195 )
2019
9
Association between preexisting lung involvements and the risk of diffuse alveolar hemorrhage in patients with microscopic polyangiitis: A multi-center retrospective cohort study. ( 30929541 )
2019
10
Neutrophil extracellular traps are associated with the pathogenesis of diffuse alveolar hemorrhage in murine lupus. ( 30930069 )
2019
11
Diffuse Alveolar Hemorrhage Following Pirfenidone Initiation. ( 30987503 )
2019
12
Influenza A Pneumonia Associated with Diffuse Alveolar Hemorrhage. A Case Report and Literature Review. ( 31019189 )
2019
13
Recurrent Episodes of Diffuse Alveolar Hemorrhage in Systemic Sclerosis 30 Days Apart. ( 31053041 )
2019
14
Diffuse alveolar hemorrhage caused by IgA deposition associated with multiple myeloma. ( 31110743 )
2019
15
Silicone pneumonitis, diffuse alveolar hemorrhage and acute respiratory distress syndrome from gluteal silicone injections. ( 30224271 )
2018
16
Mediastinal angiosarcoma presenting as diffuse alveolar hemorrhage. ( 29719795 )
2018
17
Primary antiphospholipid syndrome associated Liebman-Sachs endocarditis leading to diffuse alveolar hemorrhage: A case report. ( 30191120 )
2018
18
Difficulties in the treatment of recurring diffuse alveolar hemorrhage accompanying primary antiphospholipid syndrome: a case report and literature review. ( 29960279 )
2018
19
Analysis of three cases of diffuse alveolar hemorrhage: False-negative results in pulmonary ultrasound. ( 28027784 )
2018
20
Diffuse Alveolar Hemorrhage in IgA Vasculitis with an Atypical Presentation. ( 29033424 )
2018
21
Diffuse Alveolar Hemorrhage Developing Immediately after Immunosuppressive Treatments in a Patient with Granulomatosis with Polyangiitis Who Had Pulmonary Nodules. ( 29093401 )
2018
22
Liver X Receptor Agonist Therapy Prevents Diffuse Alveolar Hemorrhage in Murine Lupus by Repolarizing Macrophages. ( 29456535 )
2018
23
Diffuse Alveolar Hemorrhage without Extrapulmonary Manifestations: A Rare Presentation of Lupus. ( 29487279 )
2018
24
Alveolar levels of immuno-inflammatory mediators in diffuse alveolar hemorrhage after allogeneic transplant. ( 29670209 )
2018
25
Methylprednisolone and plasmapheresis are effective for life-threatening diffuse alveolar hemorrhage and gastrointestinal hemorrhage in granulomatosis with polyangiitis: A case report and literature review. ( 29703056 )
2018
26
Successful treatment with idarucizumab for diffuse alveolar hemorrhage induced by dabigatran etexilate: a case report. ( 29740732 )
2018
27
Pulmonary manifestations in systemic lupus erythematosus: pleural involvement, acute pneumonitis, chronic interstitial lung disease and diffuse alveolar hemorrhage. ( 29773465 )
2018
28
Pulmonary renal syndrome: A case report of diffuse alveolar hemorrhage in association with ANCA negative pauci-immune glomerulonephritis. ( 29879042 )
2018
29
B-cell-depleting therapy for diffuse alveolar hemorrhage in systemic lupus erythematosus. ( 29907447 )
2018
30
Diffuse alveolar hemorrhage associated with ticagrelor therapy after percutaneous coronary intervention. ( 29952365 )
2018
31
A fatal case of diffuse alveolar hemorrhage as the initial presentation of systemic lupus erythematosus: A case report and literature review. ( 29977760 )
2018
32
Severe Progressive Diffuse Alveolar Hemorrhage in a Patient with Systemic Lupus Erythematosus. ( 29984006 )
2018
33
Diffuse Alveolar Hemorrhage Induced by Vaping. ( 29984031 )
2018
34
Up in smoke: An unusual case of diffuse alveolar hemorrhage from marijuana. ( 29998053 )
2018
35
Fat embolism syndrome presenting as diffuse alveolar hemorrhage: a rare (known) association. ( 30054219 )
2018
36
Diffuse alveolar hemorrhage is most often fatal and is affected by graft source, conditioning regiment toxicity, and engraftment kinetics. ( 30076172 )
2018
37
Sitagliptin-induced diffuse alveolar hemorrhage mimicking pulmonary edema. ( 30090803 )
2018
38
Atypical rapid onset Scleroderma Renal Crisis (SRC) complicated with diffuse alveolar hemorrhage and pleuro-pericardial effusions in a patient with recently diagnosed breast cancer and a positive anti-RNA polymerase III Ab.: A case report. ( 30140606 )
2018
39
Successful Treatment of Concurrent Mucormycosis and Diffuse Alveolar Hemorrhage in a Patient With Newly Diagnosed Systemic Lupus Erythematosus. ( 30207572 )
2018
40
Systemic lupus erythematosus-associated diffuse alveolar hemorrhage: A case report and review of the literature. ( 30220838 )
2018
41
Diffuse alveolar hemorrhage with pseudoprogression during nivolumab therapy in a patient with malignant melanoma. ( 30253076 )
2018
42
Pulmonary tuberculosis presenting as diffuse alveolar hemorrhage: Believe it or not. ( 30381561 )
2018
43
A case of steroid-induced diffuse alveolar hemorrhage. ( 30381569 )
2018
44
Visceral Leishmaniasis Associated with Macrophage Activation Syndrome and Diffuse Alveolar Hemorrhage in a Lupus Patient. ( 30387429 )
2018
45
Diffuse Alveolar Hemorrhage and Pulmonary Vasculitides: Histopathologic Findings. ( 30404110 )
2018
46
Diffuse alveolar hemorrhage during alemtuzumab infusion in a patient with multiple sclerosis: a case report. ( 30454022 )
2018
47
Diffuse alveolar hemorrhage in childhood-onset systemic lupus erythematosus: a severe disease flare with serious outcome. ( 30657099 )
2018
48
Legionella pneumonia associated with severe acute respiratory distress syndrome and diffuse alveolar hemorrhage - A rare association. ( 28348947 )
2017
49
Sevoflurane Induced Diffuse Alveolar Hemorrhage in a young patient. ( 27872805 )
2017
50
The Effects of Plasma Exchange on Severe Vasculitis with Diffuse Alveolar Hemorrhage. ( 28050000 )
2017

Variations for Diffuse Alveolar Hemorrhage

Expression for Diffuse Alveolar Hemorrhage

Search GEO for disease gene expression data for Diffuse Alveolar Hemorrhage.

Pathways for Diffuse Alveolar Hemorrhage

GO Terms for Diffuse Alveolar Hemorrhage

Biological processes related to Diffuse Alveolar Hemorrhage according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 8.96 CYP2C9 VKORC1
2 drug metabolic process GO:0017144 8.62 CYP2C9 VKORC1

Molecular functions related to Diffuse Alveolar Hemorrhage according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 8.62 CYP2C9 VKORC1

Sources for Diffuse Alveolar Hemorrhage

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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