MCID: DFF031
MIFTS: 29

Diffuse Alveolar Hemorrhage

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Diffuse Alveolar Hemorrhage

MalaCards integrated aliases for Diffuse Alveolar Hemorrhage:

Name: Diffuse Alveolar Hemorrhage 59

Characteristics:

Orphanet epidemiological data:

59
diffuse alveolar hemorrhage
Prevalence: 1-9/100000 (Europe);

Classifications:

Orphanet: 59  
Rare respiratory diseases


External Ids:

Orphanet 59 ORPHA90060
ICD10 via Orphanet 34 J98.4

Summaries for Diffuse Alveolar Hemorrhage

MalaCards based summary : Diffuse Alveolar Hemorrhage is related to lupus erythematosus and systemic lupus erythematosus. An important gene associated with Diffuse Alveolar Hemorrhage is CYP2C9 (Cytochrome P450 Family 2 Subfamily C Member 9). Affiliated tissues include bone, bone marrow and lung.

Related Diseases for Diffuse Alveolar Hemorrhage

Diseases related to Diffuse Alveolar Hemorrhage via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)
# Related Disease Score Top Affiliating Genes
1 lupus erythematosus 10.6
2 systemic lupus erythematosus 10.6
3 vasculitis 10.4
4 glomerulonephritis 10.3
5 antiphospholipid syndrome 10.3
6 respiratory failure 10.3
7 granulomatosis with polyangiitis 10.2
8 microscopic polyangiitis 10.2
9 angiosarcoma 10.2
10 endocarditis 10.2
11 acute respiratory distress syndrome 10.2
12 rheumatoid arthritis 10.1
13 arthritis 10.1
14 hematopoietic stem cell transplantation 10.1
15 purpura 10.1
16 pneumonia 10.1
17 pulmonary edema 10.1
18 leptospirosis 10.1
19 rapidly progressive glomerulonephritis 10.1
20 anca-associated vasculitis 10.1
21 autoimmune disease 10.0
22 scleroderma, familial progressive 10.0
23 thrombocytopenic purpura, autoimmune 10.0
24 autoimmune disease 1 10.0
25 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.0
26 leukemia 10.0
27 thrombocytopenia 10.0
28 acute poststreptococcal glomerulonephritis 10.0
29 pulmonary tuberculosis 10.0
30 churg-strauss syndrome 10.0
31 ischemia 10.0
32 allergic angiitis 10.0
33 isolated pulmonary capillaritis 10.0
34 spondyloarthropathy 1 9.8
35 cardiac conduction defect 9.8
36 multiple sclerosis 9.8
37 renal cell carcinoma, nonpapillary 9.8
38 pheochromocytoma 9.8
39 pulmonary hemosiderosis 9.8
40 down syndrome 9.8
41 hemolytic uremic syndrome, atypical 1 9.8
42 myelofibrosis 9.8
43 pulmonary venoocclusive disease 1, autosomal dominant 9.8
44 hemophilia b 9.8
45 leukemia, acute myeloid 9.8
46 aceruloplasminemia 9.8
47 mycobacterium tuberculosis 1 9.8
48 kala-azar 1 9.8
49 myocardial infarction 9.8
50 acute promyelocytic leukemia 9.8

Graphical network of the top 20 diseases related to Diffuse Alveolar Hemorrhage:



Diseases related to Diffuse Alveolar Hemorrhage

Symptoms & Phenotypes for Diffuse Alveolar Hemorrhage

Drugs & Therapeutics for Diffuse Alveolar Hemorrhage

Search Clinical Trials , NIH Clinical Center for Diffuse Alveolar Hemorrhage

Genetic Tests for Diffuse Alveolar Hemorrhage

Anatomical Context for Diffuse Alveolar Hemorrhage

MalaCards organs/tissues related to Diffuse Alveolar Hemorrhage:

41
Bone, Bone Marrow, Lung, B Cells, Myeloid, T Cells, Thymus

Publications for Diffuse Alveolar Hemorrhage

Articles related to Diffuse Alveolar Hemorrhage:

(show top 50) (show all 320)
# Title Authors Year
1
Diffuse Alveolar Hemorrhage in IgA Vasculitis with an Atypical Presentation. ( 29033424 )
2018
2
Mediastinal angiosarcoma presenting as diffuse alveolar hemorrhage. ( 29719795 )
2018
3
B-cell-depleting therapy for diffuse alveolar hemorrhage in systemic lupus erythematosus. ( 29907447 )
2018
4
Difficulties in the treatment of recurring diffuse alveolar hemorrhage accompanying primary antiphospholipid syndrome: a case report and literature review. ( 29960279 )
2018
5
Successful treatment with idarucizumab for diffuse alveolar hemorrhage induced by dabigatran etexilate: a case report. ( 29740732 )
2018
6
Diffuse Alveolar Hemorrhage Developing Immediately after Immunosuppressive Treatments in a Patient with Granulomatosis with Polyangiitis Who Had Pulmonary Nodules. ( 29093401 )
2018
7
Pulmonary renal syndrome: A case report of diffuse alveolar hemorrhage in association with ANCA negative pauci-immune glomerulonephritis. ( 29879042 )
2018
8
A fatal case of diffuse alveolar hemorrhage as the initial presentation of systemic lupus erythematosus: A case report and literature review. ( 29977760 )
2018
9
Diffuse Alveolar Hemorrhage without Extrapulmonary Manifestations: A Rare Presentation of Lupus. ( 29487279 )
2018
10
Liver X Receptor Agonist Therapy Prevents Diffuse Alveolar Hemorrhage in Murine Lupus by Repolarizing Macrophages. ( 29456535 )
2018
11
Alveolar levels of immuno-inflammatory mediators in diffuse alveolar hemorrhage after allogeneic transplant. ( 29670209 )
2018
12
Methylprednisolone and plasmapheresis are effective for life-threatening diffuse alveolar hemorrhage and gastrointestinal hemorrhage in granulomatosis with polyangiitis: A case report and literature review. ( 29703056 )
2018
13
Pulmonary manifestations in systemic lupus erythematosus: pleural involvement, acute pneumonitis, chronic interstitial lung disease and diffuse alveolar hemorrhage. ( 29773465 )
2018
14
Silicone pneumonitis, diffuse alveolar hemorrhage and acute respiratory distress syndrome from gluteal silicone injections. ( 30224271 )
2018
15
Primary antiphospholipid syndrome associated Liebman-Sachs endocarditis leading to diffuse alveolar hemorrhage: A case report. ( 30191120 )
2018
16
Diffuse alveolar hemorrhage associated with ticagrelor therapy after percutaneous coronary intervention. ( 29952365 )
2018
17
Severe Progressive Diffuse Alveolar Hemorrhage in a Patient with Systemic Lupus Erythematosus. ( 29984006 )
2018
18
Diffuse Alveolar Hemorrhage Induced by Vaping. ( 29984031 )
2018
19
Up in smoke: An unusual case of diffuse alveolar hemorrhage from marijuana. ( 29998053 )
2018
20
Fat embolism syndrome presenting as diffuse alveolar hemorrhage: a rare (known) association. ( 30054219 )
2018
21
Diffuse alveolar hemorrhage is most often fatal and is affected by graft source, conditioning regiment toxicity, and engraftment kinetics. ( 30076172 )
2018
22
Sitagliptin-induced diffuse alveolar hemorrhage mimicking pulmonary edema. ( 30090803 )
2018
23
Atypical rapid onset Scleroderma Renal Crisis (SRC) complicated with diffuse alveolar hemorrhage and pleuro-pericardial effusions in a patient with recently diagnosed breast cancer and a positive anti-RNA polymerase III Ab.: A case report. ( 30140606 )
2018
24
Successful Treatment of Concurrent Mucormycosis and Diffuse Alveolar Hemorrhage in a Patient With Newly Diagnosed Systemic Lupus Erythematosus. ( 30207572 )
2018
25
Systemic lupus erythematosus-associated diffuse alveolar hemorrhage: A case report and review of the literature. ( 30220838 )
2018
26
Diffuse alveolar hemorrhage with pseudoprogression during nivolumab therapy in a patient with malignant melanoma. ( 30253076 )
2018
27
Pulmonary tuberculosis presenting as diffuse alveolar hemorrhage: Believe it or not. ( 30381561 )
2018
28
A case of steroid-induced diffuse alveolar hemorrhage. ( 30381569 )
2018
29
Visceral Leishmaniasis Associated with Macrophage Activation Syndrome and Diffuse Alveolar Hemorrhage in a Lupus Patient. ( 30387429 )
2018
30
Diffuse Alveolar Hemorrhage and Pulmonary Vasculitides: Histopathologic Findings. ( 30404110 )
2018
31
Diffuse alveolar hemorrhage during alemtuzumab infusion in a patient with multiple sclerosis: a case report. ( 30454022 )
2018
32
Granulomatosis with polyangiitis presenting with diffuse alveolar hemorrhage requiring extracorporeal membrane oxygenation with rapid multiorgan relapse: A case report. ( 28353556 )
2017
33
Diffuse Alveolar Hemorrhage as a Complication of Intrapleural Fibrinolytic Therapy. ( 28957896 )
2017
34
Continous Rituximab treatment for recurrent diffuse alveolar hemorrhage in a patient with systemic lupus erythematosus and antiphosholipid syndrome. ( 29021954 )
2017
35
Diffuse Alveolar Hemorrhage Induced by Irinotecan for a Patient with Metastatic Thymic Carcinoma: A Case Report and Literature Review. ( 28674360 )
2017
36
Immune diffuse alveolar hemorrhage: Clinical presentation and outcome. ( 28732837 )
2017
37
Pathogenesis of Diffuse Alveolar Hemorrhage in Murine Lupus. ( 28217966 )
2017
38
Diffuse Alveolar Hemorrhage in Autoimmune Diseases. ( 28397125 )
2017
39
A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis. ( 29423322 )
2017
40
Repeated Diffuse Alveolar Hemorrhage in a Patient with Hemophilia B. ( 28202865 )
2017
41
An interesting case of mycoplasma pneumonia associated multisystem involvement and diffuse alveolar hemorrhage. ( 28413775 )
2017
42
Clinical Features of Patients with Diffuse Alveolar Hemorrhage due to Negative-Pressure Pulmonary Edema. ( 28455784 )
2017
43
The Effects of Plasma Exchange on Severe Vasculitis with Diffuse Alveolar Hemorrhage. ( 28050000 )
2017
44
Microscopic polyangiitis: Atypical presentation with extensive small bowel necrosis, diffuse alveolar hemorrhage, and renal failure. ( 28348948 )
2017
45
Legionella pneumonia associated with severe acute respiratory distress syndrome and diffuse alveolar hemorrhage - A rare association. ( 28348947 )
2017
46
A Case of Rare Diffuse Alveolar Hemorrhage and Review of Literature. ( 29104431 )
2017
47
Diffuse Alveolar Hemorrhage in Systemic Lupus Erythematosus: Histopathologic Features and Clinical Correlations. ( 28536665 )
2017
48
Diffuse alveolar hemorrhage as an initial presentation of ANCAa89associated vasculitis in an 80a89yeara89old man. ( 28581453 )
2017
49
Pneumonitis with Diffuse Alveolar Hemorrhage Induced by Sho-seiryu-to. ( 28883249 )
2017
50
Sevoflurane Induced Diffuse Alveolar Hemorrhage in a young patient. ( 27872805 )
2017

Variations for Diffuse Alveolar Hemorrhage

Expression for Diffuse Alveolar Hemorrhage

Search GEO for disease gene expression data for Diffuse Alveolar Hemorrhage.

Pathways for Diffuse Alveolar Hemorrhage

GO Terms for Diffuse Alveolar Hemorrhage

Biological processes related to Diffuse Alveolar Hemorrhage according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 8.96 CYP2C9 VKORC1
2 drug metabolic process GO:0017144 8.62 CYP2C9 VKORC1

Molecular functions related to Diffuse Alveolar Hemorrhage according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 8.62 CYP2C9 VKORC1

Sources for Diffuse Alveolar Hemorrhage

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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