MCID: DFF015
MIFTS: 31

Diffuse Glomerulonephritis

Categories: Nephrological diseases

Aliases & Classifications for Diffuse Glomerulonephritis

MalaCards integrated aliases for Diffuse Glomerulonephritis:

Name: Diffuse Glomerulonephritis 12 15
Glomerulonephritis Diffuse 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4781
NCIt 50 C35799
UMLS 73 C0859036

Summaries for Diffuse Glomerulonephritis

MalaCards based summary : Diffuse Glomerulonephritis, also known as glomerulonephritis diffuse, is related to subacute bacterial endocarditis and glomerulonephritis. An important gene associated with Diffuse Glomerulonephritis is CFP (Complement Factor Properdin), and among its related pathways/superpathways are NF-KappaB Family Pathway and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include kidney, testes and skin, and related phenotypes are homeostasis/metabolism and cellular

Related Diseases for Diffuse Glomerulonephritis

Diseases related to Diffuse Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 179)
# Related Disease Score Top Affiliating Genes
1 subacute bacterial endocarditis 30.4 CD40LG CD79A
2 glomerulonephritis 30.0 ALB CD40LG CD79A CFP
3 acute diffuse nephritis 11.3
4 selective igg deficiency disease 10.7 CD40LG CD79A
5 c1q nephropathy 10.7 CD40LG CD79A
6 meningovascular neurosyphilis 10.7 CD40LG CD79A
7 alpha chain disease 10.7 CD40LG CD79A
8 brill-zinsser disease 10.7 CD40LG CD79A
9 exudative glomerulonephritis 10.7 CD40LG CD79A
10 salpingo-oophoritis 10.7 CD40LG CD79A
11 early yaws 10.7 CD40LG CD79A
12 ventilation pneumonitis 10.7 CD40LG CD79A
13 chronic interstitial cystitis 10.7 CD40LG CD79A
14 axillary adenitis 10.7 CD40LG CD79A
15 cryofibrinogenemia 10.7 CD40LG CD79A
16 trichostrongyloidiasis 10.7 CD40LG CD79A
17 heterophyiasis 10.7 CD40LG CD79A
18 immunoglobulin g deficiency 10.7 CD40LG CD79A
19 orbital granuloma 10.7 CD40LG CD79A
20 transient hypogammaglobulinemia of infancy 10.7 CD40LG CD79A
21 hyperglobulinemic purpura 10.7 CD40LG CD79A
22 gastroduodenitis 10.7 CD40LG CD79A
23 bacterial conjunctivitis 10.7 CD40LG CD79A
24 ulcerative blepharitis 10.7 CD79A LYZ
25 heavy chain disease 10.7 CD40LG CD79A
26 ophthalmia neonatorum 10.7 CD40LG CD79A
27 immunoglobulin a deficiency 1 10.7 CD40LG CD79A
28 parotid disease 10.7 CD40LG CD79A
29 cerebral arteritis 10.7 CD40LG CD79A
30 selective immunoglobulin deficiency disease 10.7 CD40LG CD79A
31 acute poststreptococcal glomerulonephritis 10.7 CD79A CFP
32 geniculate herpes zoster 10.7 CD40LG CD79A
33 erythema elevatum diutinum 10.7 CD40LG CD79A
34 spastic paraplegia 25, autosomal recessive 10.7 FGF13 FGF2
35 sporotrichosis 10.7 CD40LG CD79A
36 fallopian tube disease 10.7 CD40LG CD79A
37 hyperimmunoglobulin syndrome 10.7 CD40LG CD79A
38 congenital syphilis 10.7 CD40LG CD79A
39 polyclonal hypergammaglobulinemia 10.7 CD40LG CD79A
40 monoclonal paraproteinemia 10.7 CD40LG CD79A
41 salpingitis 10.7 CD40LG CD79A
42 ocular toxoplasmosis 10.7 CD40LG CD79A
43 dysgammaglobulinemia 10.7 CD40LG CD79A
44 congenital hypogammaglobulinemia 10.7 CD40LG CD79A
45 acute maxillary sinusitis 10.7 CD40LG CD79A
46 chronic polyneuropathy 10.7 CD40LG CD79A
47 spinocerebellar ataxia, autosomal recessive 10 10.7 CD40LG CD79A
48 clivus chordoma 10.7 FGF13 FGF2
49 parasitic ichthyosporea infectious disease 10.7 CD40LG CD79A
50 cd40 ligand deficiency 10.7 CD40LG CD79A

Graphical network of the top 20 diseases related to Diffuse Glomerulonephritis:



Diseases related to Diffuse Glomerulonephritis

Symptoms & Phenotypes for Diffuse Glomerulonephritis

MGI Mouse Phenotypes related to Diffuse Glomerulonephritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.07 LYZ CD79A CFP PI4K2A ESR2 ALB
2 cellular MP:0005384 10.06 LYZ CD79A ALB ESR2 FGF13 B2M
3 mortality/aging MP:0010768 10.02 LYZ CFP PI4K2A ALB ESR2 FGF13
4 cardiovascular system MP:0005385 9.98 CD40LG LYZ CFP ESR2 B2M FGF2
5 nervous system MP:0003631 9.81 LYZ CD79A PI4K2A ESR2 B2M FGF13
6 neoplasm MP:0002006 9.73 LYZ CD79A ALB ESR2 B2M FGF2
7 normal MP:0002873 9.5 LYZ CD79A CFP ALB ESR2 PI4K2A
8 renal/urinary system MP:0005367 9.1 CD40LG LYZ CD79A ALB ESR2 PI4K2A

Drugs & Therapeutics for Diffuse Glomerulonephritis

Search Clinical Trials , NIH Clinical Center for Diffuse Glomerulonephritis

Genetic Tests for Diffuse Glomerulonephritis

Anatomical Context for Diffuse Glomerulonephritis

MalaCards organs/tissues related to Diffuse Glomerulonephritis:

41
Kidney, Testes, Skin

Publications for Diffuse Glomerulonephritis

Articles related to Diffuse Glomerulonephritis:

(show all 32)
# Title Authors Year
1
Proliferative Diffuse Glomerulonephritis in Rheumatoid Arthritis. ( 29200028 )
2017
2
Diffuse glomerulonephritis associated with rifampicin treatment for tuberculosis. ( 12109797 )
2002
3
An epizootic of diffuse glomerulonephritis in white perch (Roccus americanus) from a heavily polluted industrial basin in Lake Ontario. ( 7147623 )
1982
4
Mesangiocapillary glomerulonephritis in lambs: the ultrastructure and immunopathology of diffuse glomerulonephritis in newly born Finnish Landrace lambs. ( 7007596 )
1980
5
Diffuse glomerulonephritis in rabbits with Streptococcus viridans endocarditis. ( 125360 )
1975
6
The use of indometacin for treating diffuse glomerulonephritis under experimental and clinical conditions. ( 4800460 )
1973
7
Cerebrospinal fluid and blood catecholamines in chronic diffuse glomerulonephritis. ( 5512141 )
1970
8
'Shunt nephritis': diffuse glomerulonephritis complicating ventriculo-atrial shunts. ( 5276399 )
1970
9
Diffuse glomerulonephritis associated with infected ventriculoatrial shunt. ( 4905011 )
1970
10
Acute diffuse glomerulonephritis in acute staphylococcal endocarditis. ( 4184387 )
1969
11
Diffuse glomerulonephritis associated with infected ventriculoatrial shunt. ( 4176718 )
1968
12
Histopathological aspects of acute diffuse glomerulonephritis in children. ( 6032135 )
1967
13
New classification of diffuse glomerulonephritis based on prognosis, especially new proposal of subchronic glomerulonephritis. ( 5925781 )
1966
14
Prognostic implications of certain kidney function tests in diffuse glomerulonephritis. ( 13937373 )
1963
15
Acute diffuse glomerulonephritis with the nephrotic syndrome. ( 13906879 )
1962
16
A study of acute diffuse glomerulonephritis in children. ( 13746338 )
1961
17
Diffuse glomerulonephritis as a complication of subacute bacterial endocarditis. ( 13538751 )
1958
18
The pathogenesis of acute diffuse glomerulonephritis. ( 13546960 )
1958
19
Glomerular filtration rate and renal blood flow in patients with chronic diffuse glomerulonephritis during pregnancy. ( 13301449 )
1956
20
Auto-antibodies and skin tests with extracts from normal kidney in cases of diffuse glomerulonephritis. ( 13398158 )
1956
21
Diffuse glomerulonephritis induced in rabbits by small intravenous injections of horse serum. ( 14789329 )
1951
22
Acute diffuse glomerulonephritis. ( 18139421 )
1949
23
Diffuse glomerulonephritis produced in rabbits by massive injections of bovine serum gamma globulin. ( 18120094 )
1949
24
A consideration of diffuse glomerulonephritis. ( 18146355 )
1949
25
Acute diffuse glomerulonephritis. ( 18139417 )
1949
26
Diffuse glomerulonephritis; suggested classification with special reference to so-called lipoid nephrosis. ( 18859429 )
1948
27
Acute degenerative, exudative, and proliferative glomerulonephritis superimposed on chronic diffuse glomerulonephritis. ( 20269631 )
1947
28
Renal extraction of p-aminohippurate in normal subjects and in essential hypertension and chronic diffuse glomerulonephritis. ( 20342505 )
1947
29
GLOMERULONEPHRITIS. A SURVEY OF THE FUNCTIONAL ORGANIZATION OF THE KIDNEY IN VARIOUS STAGES OF DIFFUSE GLOMERULONEPHRITIS. ( 16695078 )
1944
30
THE EFFECT OF PREGNANCY ON RENAL FUNCTION IN WOMEN WITH PRE-EXISTING ESSENTIAL HYPERTENSION AND WITH CHRONIC DIFFUSE GLOMERULONEPHRITIS. ( 16695157 )
1944
31
Diffuse Glomerulonephritis Following Revaccination for Smallpox. ( 19970781 )
1944
32
Acute Diffuse Glomerulonephritis. ( 18743918 )
1937

Variations for Diffuse Glomerulonephritis

Expression for Diffuse Glomerulonephritis

Search GEO for disease gene expression data for Diffuse Glomerulonephritis.

Pathways for Diffuse Glomerulonephritis

Pathways related to Diffuse Glomerulonephritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.87 CD40LG FGF13 FGF2 TGFB3
2 10.92 ALB FGF13 FGF2
3 10.57 FGF2 TGFB3

GO Terms for Diffuse Glomerulonephritis

Cellular components related to Diffuse Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.8 ALB B2M CD40LG CFP FGF2 LYZ
2 specific granule lumen GO:0035580 9.33 B2M CFP LYZ
3 extracellular region GO:0005576 9.28 ALB B2M CD40LG CFP ESR2 FGF13
4 tertiary granule lumen GO:1904724 9.13 B2M CFP LYZ

Biological processes related to Diffuse Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.26 CD40LG FGF13 FGF2 TGFB3
2 B cell proliferation GO:0042100 9.16 CD40LG CD79A
3 retina homeostasis GO:0001895 8.8 ALB B2M LYZ

Molecular functions related to Diffuse Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.35 ALB B2M ESR2 LYZ TGFB3
2 growth factor activity GO:0008083 8.8 FGF13 FGF2 TGFB3

Sources for Diffuse Glomerulonephritis

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28 GO
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69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
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74 UMLS via Orphanet
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