MCID: DFF015
MIFTS: 26

Diffuse Glomerulonephritis

Categories: Nephrological diseases

Aliases & Classifications for Diffuse Glomerulonephritis

MalaCards integrated aliases for Diffuse Glomerulonephritis:

Name: Diffuse Glomerulonephritis 12 15
Glomerulonephritis Diffuse 70

Classifications:



External Ids:

Disease Ontology 12 DOID:4781
NCIt 50 C35799
UMLS 70 C0859036

Summaries for Diffuse Glomerulonephritis

MalaCards based summary : Diffuse Glomerulonephritis, also known as glomerulonephritis diffuse, is related to glomerulonephritis and membranoproliferative glomerulonephritis. An important gene associated with Diffuse Glomerulonephritis is MTUS1 (Microtubule Associated Scaffold Protein 1), and among its related pathways/superpathways are Axon guidance and Immune response Lectin induced complement pathway. Affiliated tissues include kidney, bone marrow and skin.

Related Diseases for Diffuse Glomerulonephritis

Diseases related to Diffuse Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)
# Related Disease Score Top Affiliating Genes
1 glomerulonephritis 31.3 MASP1 CFP C3
2 membranoproliferative glomerulonephritis 29.5 CFP C3
3 acute diffuse nephritis 11.3
4 endocarditis 10.1
5 nephrotic syndrome 10.1
6 proteinuria, chronic benign 10.1
7 uremia 10.1
8 c3 glomerulopathy 10.0 CFP C3
9 neisseria meningitidis infection 10.0 CFP C3
10 hypertension, essential 10.0
11 variola major 10.0
12 pyelonephritis 10.0
13 acute kidney failure 10.0
14 proliferative glomerulonephritis 10.0
15 smallpox 10.0
16 complement factor i deficiency 10.0 CFP C3
17 scarlet fever 10.0 CFP C3
18 complement component 5 deficiency 10.0 CFP C3
19 acute poststreptococcal glomerulonephritis 10.0 CFP C3
20 rapidly progressive glomerulonephritis 10.0 CFP C3
21 hypersensitivity reaction type iii disease 10.0 CFP C3
22 3mc syndrome 9.9 MASP1 CFP
23 systemic lupus erythematosus 9.9
24 infective endocarditis 9.9
25 alport syndrome 9.9
26 anuria 9.9
27 kidney disease 9.9
28 complement deficiency 9.9 CFP C3
29 bacterial meningitis 9.8 CFP C3
30 complement component 3 deficiency 9.8 MASP1 CFP C3
31 progressive relapsing multiple sclerosis 9.8 MASP1 CFP C3
32 iga glomerulonephritis 9.8 MASP1 CFP C3
33 rheumatoid arthritis 9.8
34 sarcoidosis 1 9.8
35 pulmonary hypertension 9.8
36 parotitis 9.8
37 tonsillitis 9.8
38 interstitial nephritis 9.8
39 mesenteric lymphadenitis 9.8
40 hydrocephalus 9.8
41 lipoid nephrosis 9.8
42 disseminated intravascular coagulation 9.8
43 cerebral arteritis 9.8
44 pulmonary edema 9.8
45 nephrosclerosis 9.8
46 pulmonary sarcoidosis 9.8
47 lymphadenitis 9.8
48 calcinosis 9.8
49 arteriosclerosis 9.8
50 subacute bacterial endocarditis 9.8

Graphical network of the top 20 diseases related to Diffuse Glomerulonephritis:



Diseases related to Diffuse Glomerulonephritis

Symptoms & Phenotypes for Diffuse Glomerulonephritis

Drugs & Therapeutics for Diffuse Glomerulonephritis

Search Clinical Trials , NIH Clinical Center for Diffuse Glomerulonephritis

Genetic Tests for Diffuse Glomerulonephritis

Anatomical Context for Diffuse Glomerulonephritis

MalaCards organs/tissues related to Diffuse Glomerulonephritis:

40
Kidney, Bone Marrow, Skin, T Cells

Publications for Diffuse Glomerulonephritis

Articles related to Diffuse Glomerulonephritis:

(show top 50) (show all 409)
# Title Authors PMID Year
1
Ultrasonography of the Kidneys in Healthy and Diseased Camels (Camelus dromedarius). 61
33144934 2020
2
Proliferative Diffuse Glomerulonephritis in Rheumatoid Arthritis. 61
29200028 2018
3
Trans-resveratrol mitigates type 1 diabetes-induced oxidative DNA damage and accumulation of advanced glycation end products in glomeruli and tubules of rat kidneys. 61
29229234 2018
4
Epithelial-mesenchymal transition in pediatric nephropathies. 61
27707584 2016
5
[GOODPASTURE'S SYNDROME--CASE REPORTS]. 61
26380476 2015
6
Massive proteinuria and acute glomerulonephritis picture in a patient with Familial Mediterranean fever and E148Q mutation. 61
25362225 2014
7
Vasculitis in the intensive care unit. 61
23507060 2013
8
Prevalence of nephropathies in children and adolescents and alterations in renal biopsies in Minas Gerais, Brazil, from 1996 to 2010. 61
22658343 2013
9
Understanding lupus nephritis: diagnosis, management, and treatment options. 61
22675266 2012
10
Proliferative glomerulonephritis in lupus patients with human immunodeficiency virus infection: a difficult clinical challenge. 61
20132967 2010
11
Familial Mediterranean fever and membranous glomerulonephritis: report of a case. 61
20370460 2010
12
MPO-ANCA- and IgA-positive systemic vasculitis: a possibly overlapping syndrome of microscopic polyangiitis and Henoch-Schoenlein purpura. 61
19586496 2009
13
The spectrum of adult postinfectious glomerulonephritis in the new millennium. 61
19814634 2009
14
Kidney allocation to liver transplant candidates with renal failure of undetermined etiology: role of percutaneous renal biopsy. 61
19032225 2008
15
IgA nephropathy in children and adults: comparison of histologic features and clinical outcomes. 61
18263928 2008
16
Noncongophilic fibrillary glomerulonephritis in a cat. 61
18487491 2008
17
[Correlation analysis on blood stasis syndrome, clinical features and renal pathology in 174 patients with primary glomerular diseases]. 61
17633356 2007
18
[Wegener's granulomatosis]. 61
17363211 2007
19
The pathology of lupus nephritis. 61
17336686 2007
20
[Cerebral venous thrombosis as the presenting symptom of systemic lupus erythematosus]. 61
15257524 2004
21
The classification of glomerulonephritis in systemic lupus erythematosus revisited. 61
14747370 2004
22
The classification of glomerulonephritis in systemic lupus erythematosus revisited. 61
14717922 2004
23
Diffuse glomerulonephritis associated with rifampicin treatment for tuberculosis. 61
12109797 2002
24
[Paratuberculous nephritis]. 61
12416224 2002
25
CD4(+) T cells participate in the nephropathy of canine visceral leishmaniasis. 61
11105098 2000
26
Rheumatic diseases in an MRL strain of mice with a deficit in the functional Fas ligand. 61
9182916 1997
27
Morphologic, immunohistochemical, and ultrastructural characterization of a distinctive renal lesion in dogs putatively associated with Borrelia burgdorferi infection: 49 cases (1987-1992). 61
9066075 1997
28
[Lupus nephritis: clinico-morphologic correlation]. 61
9102935 1996
29
[Lupus glomerulonephritis--clinico-morphologic correlation]. 61
9102934 1996
30
[The immunogenetic parameters in acute and chronic glomerulonephritis in children]. 61
7618228 1995
31
[Study of correlation between urinary IL-6 level and mesangial lesion in childhood onset IgA nephropathy]. 61
7959587 1994
32
[The health status dynamics of schoolchildren and the importance of biomedical factors in its development]. 61
7687498 1993
33
[Edema in acute diffuse glomerulonephritis, rheumatic peliosis and epidemic parotitis]. 61
1461783 1992
34
[The clinico-immunological subtypes of systemic lupus erythematosus]. 61
1455378 1992
35
[Kidney involvement in infectious endocarditis (hematuria)]. 61
1759203 1991
36
Effects of atrial natriuretic peptide on urinary protein excretion in mesangial proliferative glomerulonephritis. 61
1830375 1991
37
[Urinary prostaglandin levels in patients with arterial hypertension with benign and malignant course]. 61
2335858 1990
38
[Na-Li countertransport and the diagnosis of hypertension and combined hypertension and renal artery stenosis]. 61
2218910 1990
39
[Epidemiologic study of pregnancy complicated by lupus]. 61
2369013 1990
40
[Detection of concomitant pathology in patients with arterial hypertension by structural and functional changes of erythrocyte membranes]. 61
2779159 1989
41
[Histopathologic study of primary glomerulopathies: retrospective analysis of 197 renal biopsies (1985-1987)]. 61
2616996 1989
42
[Sodium and lithium transport and steroid hormones of the adrenal glands]. 61
2718020 1989
43
[Clinical importance of determining Na-Li countertransport in patients with arterial hypertension]. 61
3199650 1988
44
[Clinical value of determining Na-Li countertransport in the diagnosis of arterial hypertension associated with minor urinary syndrome]. 61
3401339 1988
45
Extracorporeal methods in the management of severe and malignant arterial hypertension. 61
3243217 1988
46
Quantitation of retroviral gp70 antigen, autoantibodies, and immune complexes in extravascular space in arthritic MRL-lpr/lpr mice. Use of a subcutaneously implanted tissue cage model. 61
3689461 1987
47
[Acute diffuse glomerulonephritis]. 61
3436454 1987
48
[Survival of patients with diffuse glomerulonephritis in disseminated lupus erythematosus treated with a combination of anticoagulants, corticosteroids and immunosuppressants]. 61
3590722 1987
49
[Lesions of target organs in arterial hypertension]. 61
2948050 1986
50
[Clinical pharmacology of membrane-destabilizing processes in nephropathies in children]. 61
3770164 1986

Variations for Diffuse Glomerulonephritis

Expression for Diffuse Glomerulonephritis

Search GEO for disease gene expression data for Diffuse Glomerulonephritis.

Pathways for Diffuse Glomerulonephritis

Pathways related to Diffuse Glomerulonephritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.59 SEMA6C SEMA5B SEMA4G
2
Show member pathways
11.33 MASP1 CFP C3
3 11.3 MASP1 C3
4
Show member pathways
11.14 SEMA5B CFP
5
Show member pathways
10.71 MASP1 CFP C3

GO Terms for Diffuse Glomerulonephritis

Cellular components related to Diffuse Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.1 SEMA6C SEMA4G MTUS1 MASP1 CFP C3

Biological processes related to Diffuse Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell migration GO:0030335 9.61 SEMA6C SEMA5B SEMA4G
2 axon guidance GO:0007411 9.58 SEMA6C SEMA5B SEMA4G
3 complement activation GO:0006956 9.5 MASP1 CFP C3
4 neural crest cell migration GO:0001755 9.43 SEMA6C SEMA5B SEMA4G
5 complement activation, alternative pathway GO:0006957 9.37 CFP C3
6 negative chemotaxis GO:0050919 9.33 SEMA6C SEMA5B SEMA4G
7 semaphorin-plexin signaling pathway GO:0071526 9.13 SEMA6C SEMA5B SEMA4G
8 negative regulation of axon extension involved in axon guidance GO:0048843 8.8 SEMA6C SEMA5B SEMA4G

Molecular functions related to Diffuse Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemorepellent activity GO:0045499 9.13 SEMA6C SEMA5B SEMA4G
2 semaphorin receptor binding GO:0030215 8.8 SEMA6C SEMA5B SEMA4G

Sources for Diffuse Glomerulonephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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