MCID: DFF015
MIFTS: 30

Diffuse Glomerulonephritis

Categories: Nephrological diseases

Aliases & Classifications for Diffuse Glomerulonephritis

MalaCards integrated aliases for Diffuse Glomerulonephritis:

Name: Diffuse Glomerulonephritis 12 15
Glomerulonephritis Diffuse 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4781
NCIt 50 C35799
UMLS 73 C0859036

Summaries for Diffuse Glomerulonephritis

MalaCards based summary : Diffuse Glomerulonephritis, also known as glomerulonephritis diffuse, is related to acute diffuse nephritis and glomerulonephritis. An important gene associated with Diffuse Glomerulonephritis is CFP (Complement Factor Properdin), and among its related pathways/superpathways are G-protein signaling_RhoA regulation pathway and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include kidney, testes and skin, and related phenotypes are cellular and homeostasis/metabolism

Related Diseases for Diffuse Glomerulonephritis

Diseases related to Diffuse Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
# Related Disease Score Top Affiliating Genes
1 acute diffuse nephritis 11.5
2 glomerulonephritis 10.4
3 al amyloidosis 10.1 B2M LYZ
4 nodular nonsuppurative panniculitis 10.1 CFP LYZ
5 hereditary amyloidosis 10.1 B2M LYZ
6 spastic paraplegia 25, autosomal recessive 10.1 FGF13 FGF2
7 pyelitis 10.1 B2M LYZ
8 gastric signet ring cell adenocarcinoma 10.1 FGF13 FGF2
9 synovial chondromatosis 10.1 FGF2 TGFB3
10 renal tuberculosis 10.1 B2M LYZ
11 clivus chordoma 10.1 FGF13 FGF2
12 retinitis pigmentosa 7 10.1 B2M LYZ
13 brachydactyly, type b2 10.1 FGF13 FGF2
14 in situ pulmonary adenocarcinoma 10.1 ESR2 LYZ
15 carbuncle 10.1 FGF2 LYZ
16 brachydactyly, type b1 10.1 FGF13 FGF2
17 juvenile nasopharyngeal angiofibroma 10.1 FGF2 TGFB3
18 disuse amblyopia 10.1 FGF13 FGF2
19 kidney papillary necrosis 10.1 ALB LYZ
20 ulcerative stomatitis 10.1 ALB LYZ
21 immunodeficiency 43 10.0 ALB B2M
22 cecum adenocarcinoma 10.0 B2M FGF2
23 orthostatic proteinuria 10.0 ALB B2M
24 non-secretory myeloma 10.0 ALB B2M
25 amyloidosis, familial visceral 10.0 B2M LYZ
26 danubian endemic familial nephropathy 10.0 ALB B2M
27 membranoproliferative glomerulonephritis 10.0 ALB CFP
28 decubitus ulcer 10.0 ALB FGF2
29 hemorrhagic fever 10.0 ALB B2M
30 crouzon syndrome 10.0 FGF13 FGF2
31 chronic ulcer of skin 10.0 ALB FGF2
32 acute kidney tubular necrosis 10.0 ALB B2M
33 muenke syndrome 10.0 FGF13 FGF2
34 meningoencephalitis 10.0 ALB B2M
35 hemorrhagic fever with renal syndrome 10.0 ALB B2M
36 meningitis 10.0 ALB CFP LYZ
37 acute kidney failure 10.0 ALB B2M
38 endocarditis 9.9
39 urinary system disease 9.9 ALB B2M LYZ
40 hydronephrosis 9.9 ALB B2M
41 urinary tract obstruction 9.9 ALB B2M
42 hypertension, essential 9.8
43 bacterial meningitis 9.8 ALB CFP
44 myeloma, multiple 9.8 ALB B2M FGF2
45 rheumatoid arthritis 9.7
46 arthritis 9.7
47 lipoid nephrosis 9.7
48 nephrotic syndrome 9.7
49 subacute bacterial endocarditis 9.7
50 proliferative glomerulonephritis 9.7

Graphical network of the top 20 diseases related to Diffuse Glomerulonephritis:



Diseases related to Diffuse Glomerulonephritis

Symptoms & Phenotypes for Diffuse Glomerulonephritis

MGI Mouse Phenotypes related to Diffuse Glomerulonephritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.95 ALB B2M ESR2 FGF13 FGF2 LYZ
2 homeostasis/metabolism MP:0005376 9.92 ALB B2M CFP ESR2 FGF2 LYZ
3 cardiovascular system MP:0005385 9.91 B2M CFP ESR2 FGF2 LYZ TGFB3
4 mortality/aging MP:0010768 9.91 ALB B2M CFP ESR2 FGF13 FGF2
5 digestive/alimentary MP:0005381 9.77 ALB B2M ESR2 LYZ TGFB3
6 neoplasm MP:0002006 9.55 ALB B2M ESR2 FGF2 LYZ
7 nervous system MP:0003631 9.5 B2M ESR2 FGF13 FGF2 LYZ PI4K2A
8 normal MP:0002873 9.1 ALB CFP ESR2 LYZ PI4K2A TGFB3

Drugs & Therapeutics for Diffuse Glomerulonephritis

Search Clinical Trials , NIH Clinical Center for Diffuse Glomerulonephritis

Genetic Tests for Diffuse Glomerulonephritis

Anatomical Context for Diffuse Glomerulonephritis

MalaCards organs/tissues related to Diffuse Glomerulonephritis:

41
Kidney, Testes, Skin

Publications for Diffuse Glomerulonephritis

Articles related to Diffuse Glomerulonephritis:

(show all 32)
# Title Authors Year
1
Proliferative Diffuse Glomerulonephritis in Rheumatoid Arthritis. ( 29200028 )
2017
2
Diffuse glomerulonephritis associated with rifampicin treatment for tuberculosis. ( 12109797 )
2002
3
An epizootic of diffuse glomerulonephritis in white perch (Roccus americanus) from a heavily polluted industrial basin in Lake Ontario. ( 7147623 )
1982
4
Mesangiocapillary glomerulonephritis in lambs: the ultrastructure and immunopathology of diffuse glomerulonephritis in newly born Finnish Landrace lambs. ( 7007596 )
1980
5
Diffuse glomerulonephritis in rabbits with Streptococcus viridans endocarditis. ( 125360 )
1975
6
The use of indometacin for treating diffuse glomerulonephritis under experimental and clinical conditions. ( 4800460 )
1973
7
Cerebrospinal fluid and blood catecholamines in chronic diffuse glomerulonephritis. ( 5512141 )
1970
8
'Shunt nephritis': diffuse glomerulonephritis complicating ventriculo-atrial shunts. ( 5276399 )
1970
9
Diffuse glomerulonephritis associated with infected ventriculoatrial shunt. ( 4905011 )
1970
10
Acute diffuse glomerulonephritis in acute staphylococcal endocarditis. ( 4184387 )
1969
11
Diffuse glomerulonephritis associated with infected ventriculoatrial shunt. ( 4176718 )
1968
12
Histopathological aspects of acute diffuse glomerulonephritis in children. ( 6032135 )
1967
13
New classification of diffuse glomerulonephritis based on prognosis, especially new proposal of subchronic glomerulonephritis. ( 5925781 )
1966
14
Prognostic implications of certain kidney function tests in diffuse glomerulonephritis. ( 13937373 )
1963
15
Acute diffuse glomerulonephritis with the nephrotic syndrome. ( 13906879 )
1962
16
A study of acute diffuse glomerulonephritis in children. ( 13746338 )
1961
17
Diffuse glomerulonephritis as a complication of subacute bacterial endocarditis. ( 13538751 )
1958
18
The pathogenesis of acute diffuse glomerulonephritis. ( 13546960 )
1958
19
Glomerular filtration rate and renal blood flow in patients with chronic diffuse glomerulonephritis during pregnancy. ( 13301449 )
1956
20
Auto-antibodies and skin tests with extracts from normal kidney in cases of diffuse glomerulonephritis. ( 13398158 )
1956
21
Diffuse glomerulonephritis induced in rabbits by small intravenous injections of horse serum. ( 14789329 )
1951
22
Acute diffuse glomerulonephritis. ( 18139421 )
1949
23
Diffuse glomerulonephritis produced in rabbits by massive injections of bovine serum gamma globulin. ( 18120094 )
1949
24
A consideration of diffuse glomerulonephritis. ( 18146355 )
1949
25
Acute diffuse glomerulonephritis. ( 18139417 )
1949
26
Diffuse glomerulonephritis; suggested classification with special reference to so-called lipoid nephrosis. ( 18859429 )
1948
27
Acute degenerative, exudative, and proliferative glomerulonephritis superimposed on chronic diffuse glomerulonephritis. ( 20269631 )
1947
28
Renal extraction of p-aminohippurate in normal subjects and in essential hypertension and chronic diffuse glomerulonephritis. ( 20342505 )
1947
29
GLOMERULONEPHRITIS. A SURVEY OF THE FUNCTIONAL ORGANIZATION OF THE KIDNEY IN VARIOUS STAGES OF DIFFUSE GLOMERULONEPHRITIS. ( 16695078 )
1944
30
THE EFFECT OF PREGNANCY ON RENAL FUNCTION IN WOMEN WITH PRE-EXISTING ESSENTIAL HYPERTENSION AND WITH CHRONIC DIFFUSE GLOMERULONEPHRITIS. ( 16695157 )
1944
31
Diffuse Glomerulonephritis Following Revaccination for Smallpox. ( 19970781 )
1944
32
Acute Diffuse Glomerulonephritis. ( 18743918 )
1937

Variations for Diffuse Glomerulonephritis

Expression for Diffuse Glomerulonephritis

Search GEO for disease gene expression data for Diffuse Glomerulonephritis.

Pathways for Diffuse Glomerulonephritis

Pathways related to Diffuse Glomerulonephritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.12 FGF13 FGF2 TGFB3
2 10.92 ALB FGF13 FGF2
3 10.84 FGF2 TGFB3
4 10.37 FGF2 TGFB3

GO Terms for Diffuse Glomerulonephritis

Cellular components related to Diffuse Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.73 ALB B2M CFP FGF2 LYZ TGFB3
2 endoplasmic reticulum lumen GO:0005788 9.5 ALB B2M CFP
3 specific granule lumen GO:0035580 9.33 B2M CFP LYZ
4 extracellular region GO:0005576 9.23 ALB B2M CFP ESR2 FGF13 FGF2
5 tertiary granule lumen GO:1904724 9.13 B2M CFP LYZ

Biological processes related to Diffuse Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell division GO:0051781 9.16 FGF2 TGFB3
2 cellular protein metabolic process GO:0044267 9.13 ALB B2M LYZ
3 retina homeostasis GO:0001895 8.8 ALB B2M LYZ

Molecular functions related to Diffuse Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.13 FGF13 FGF2 TGFB3
2 identical protein binding GO:0042802 9.02 ALB B2M ESR2 LYZ TGFB3

Sources for Diffuse Glomerulonephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....