MCID: DFF009
MIFTS: 24

Diffuse Lipomatosis

Categories: Skin diseases

Aliases & Classifications for Diffuse Lipomatosis

MalaCards integrated aliases for Diffuse Lipomatosis:

Name: Diffuse Lipomatosis 12 15 17 71

Classifications:



External Ids:

Disease Ontology 12 DOID:3923
NCIt 50 C6504
UMLS 71 C1333298

Summaries for Diffuse Lipomatosis

MalaCards based summary : Diffuse Lipomatosis is related to pleomorphic lipoma and lipomatosis, multiple. An important gene associated with Diffuse Lipomatosis is HOXC13-AS (HOXC13 Antisense RNA), and among its related pathways/superpathways are Bladder cancer and Integrated Cancer Pathway. Affiliated tissues include thyroid, small intestine and salivary gland.

Related Diseases for Diffuse Lipomatosis

Diseases related to Diffuse Lipomatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
# Related Disease Score Top Affiliating Genes
1 pleomorphic lipoma 30.3 MDM2 CDK4
2 lipomatosis, multiple 30.2 MDM2 CDK4
3 lipomatosis 10.6
4 goiter 10.2
5 ring chromosome 7 10.1 MDM2 CDK4
6 overgrowth syndrome 10.1
7 ring chromosome 10.1 MDM2 CDK4
8 mediastinum liposarcoma 10.1 MDM2 CDK4
9 gastric liposarcoma 10.1 MDM2 CDK4
10 infiltrating lipoma 10.1 MDM2 CDK4
11 spindle cell liposarcoma 10.1 MDM2 CDK4
12 pediatric liposarcoma 10.1 MDM2 CDK4
13 undifferentiated embryonal sarcoma of the liver 10.1 MDM2 CDK4
14 embryonal sarcoma 10.1 MDM2 CDK4
15 lipoblastoma 10.1 MDM2 CDK4
16 malignant inflammatory fibrous histiocytoma 10.1 MDM2 CDK4
17 liposarcoma of bone 10.1 MDM2 CDK4
18 pancreas sarcoma 10.1 MDM2 CDK4
19 paratesticular lipoma 10.1 MDM2 CDK4
20 lipoma of spermatic cord 10.1 MDM2 CDK4
21 adult liposarcoma 10.1 MDM2 CDK4
22 mixed liposarcoma 10.1 MDM2 CDK4
23 hereditary melanoma 10.1 MDM2 CDK4
24 infiltrating angiolipoma 10.1 MDM2 CDK4
25 peripheral osteosarcoma 10.1 MDM2 CDK4
26 juxtacortical osteosarcoma 10.1 MDM2 CDK4
27 extraosseous osteosarcoma 10.1 MDM2 CDK4
28 retroperitoneal sarcoma 10.1 MDM2 CDK4
29 parameningeal embryonal rhabdomyosarcoma 10.1 MDM2 CDK4
30 embryonal rhabdomyosarcoma 10.1 MDM2 CDK4
31 spindle cell lipoma 10.1 MDM2 CDK4
32 myositis ossificans 10.1 MDM2 CDK4
33 cellular myxoid liposarcoma 10.1 MDM2 CDK4
34 ischemic fasciitis 10.1 MDM2 CDK4
35 retroperitoneum carcinoma 10.1 MDM2 CDK4
36 familial retinoblastoma 10.1 MDM2 CDK4
37 conventional central osteosarcoma 10.0 MDM2 CDK4
38 pleomorphic liposarcoma 10.0 MDM2 CDK4
39 connective tissue benign neoplasm 10.0 MDM2 CDK4
40 well-differentiated liposarcoma 10.0 MDM2 CDK4
41 myxofibrosarcoma 10.0 MDM2 CDK4
42 tuberous sclerosis 10.0
43 papillary carcinoma 10.0
44 liposarcoma 10.0
45 bone osteosarcoma 10.0 MDM2 CDK4
46 muscle cancer 10.0 MDM2 CDK4
47 malignant fibrous histiocytoma 9.9 MDM2 CDK4
48 dedifferentiated liposarcoma 9.9 MDM2 CDK4
49 retinal cancer 9.8 MIRLET7B MDM2 CDK4
50 rhabdomyosarcoma 2 9.8 MDM2 CDK4

Graphical network of the top 20 diseases related to Diffuse Lipomatosis:



Diseases related to Diffuse Lipomatosis

Symptoms & Phenotypes for Diffuse Lipomatosis

Drugs & Therapeutics for Diffuse Lipomatosis

Search Clinical Trials , NIH Clinical Center for Diffuse Lipomatosis

Genetic Tests for Diffuse Lipomatosis

Anatomical Context for Diffuse Lipomatosis

MalaCards organs/tissues related to Diffuse Lipomatosis:

40
Thyroid, Small Intestine, Salivary Gland, Uterus

Publications for Diffuse Lipomatosis

Articles related to Diffuse Lipomatosis:

(show top 50) (show all 57)
# Title Authors PMID Year
1
Superimposed mosaicism in tuberous sclerosis complex: a key to understanding all of the manifold manifestations? 61
32396651 2020
2
A case report of Madelung's disease. 61
33143399 2020
3
Thoracic spine fracture associated with an extradural lipoma: Case report and systematic review of the literature. 61
32913612 2020
4
Lipomatosis of spinal epidural space, peritoneum, and renal sinus: a rare complication of long-term steroid therapy in a child with nephrotic syndrome. 61
30941508 2019
5
Laparoscopic resection of large pelvic lipoma causing obstructive uropathy in a 66 year old female - A case report from Greece. 61
30317275 2018
6
An Enlarged Goiter Presenting with a Rare Diffuse Lipomatosis of the Thyroid Gland. 61
29987269 2018
7
Tuberous Sclerosis Complex and Diffuse Lipomatosis: Case Report of a Rare Association. 61
29441296 2018
8
[Nevus lipomatosus cutaneous superficialis. Report of four cases including an unusual presentation associated with massive lipomas and diffuse lipomatosis]. 61
29290322 2018
9
Multiple symmetric lipomatosis and gynecomastia: A case report and relative literature review. 61
28438575 2017
10
CT and MR imaging features of diffuse lipomatosis of the abdomen. 61
27138071 2016
11
Diffuse lipomatosis of the thyroid gland with papillary microcarcinoma: Report of a rare entity. 61
26275261 2015
12
Loss of mitochondrial SDHB expression: what is its role in diffuse thyroid lipomatosis? 61
25679879 2015
13
Diffuse lipomatosis of the chest wall: report of a neonatal case. 61
25555958 2015
14
[Diffuse lipomatosis in amyloidotic goiter]. 61
26707670 2015
15
Diffuse lipomatosis of the thyroid gland. 61
23945482 2013
16
Fat-containing salivary gland tumors: a review. 61
23821211 2013
17
Madelung's disease associated with polyneuropathy and symptomatic hypokalemia. 61
23623508 2013
18
Diffuse lipomatosis of the thyroid with amyloid deposition. 61
23339824 2013
19
First description of inhibition of let-7 microRNA expression and HMGA2 overexpression in a case of deep-seated diffuse lipomatosis. 61
22642449 2012
20
Atypical diffuse lipomatosis with multifocal abdominal involvement: a case report. 61
20541989 2010
21
Diffuse lipomatosis of thyroid with hyperthyroidism. 61
20393249 2010
22
Laryngeal lipoma associated with diffuse lipomatosis: case report and literature review. 61
20155698 2010
23
Thyrolipoma and thyrolipomatosis: 5 case reports and historical review of the literature. 61
19917474 2009
24
Madelung's disease as a rare cause of obstructive sleep apnea. 61
19918637 2009
25
Diffuse lipomatosis of the thyroid gland: a pathologic curiosity. 61
19332917 2009
26
Complicated diffuse lipomatosis mimicking ascites. 61
18358964 2008
27
Diffuse lipomatosis of thyroid gland. 61
18178906 2008
28
Lipomatous lesions of the parotid gland. 61
17052582 2006
29
Giant nevi: a review. 61
17119398 2006
30
Recurrent diffuse lipomatosis of the neck--a case report. 61
15471125 2004
31
Epidural, paraspinal, and subcutaneous lipomatosis. 61
12851798 2003
32
Diffuse lipomatosis of thyroid gland. 61
10214903 1999
33
[Precordial discomfort and ECG changes of repolarization associated with hypomagnesemia in a young women following colectomy for diffuse colonic lipomatosis]. 61
9549292 1997
34
Diffuse lipomatosis: imaging features. 61
9526805 1997
35
Uterine leiomyoma with a focus of fatty and cartilaginous differentiation. 61
8389520 1993
36
[Proteus syndrome]. 61
8279789 1993
37
Diffuse lipomatosis involving the thoracic and abdominal wall: CT features. 61
1825832 1991
38
Thyroid neoplasms containing mature fat: a report of two cases and review of the literature. 61
2682616 1989
39
Multiple familial angiolipomatosis: treatment of liposuction. 61
3358622 1988
40
Diffuse lipomatosis and tuberous sclerosis. 61
3777976 1986
41
Bannayan syndrome--generalized lipomatosis associated with megalencephaly and macrodactyly. 61
3705960 1986
42
Adenolipoma of the thyroid gland. 61
3957249 1986
43
Lipomatous lesions of the thyroid gland: a review. 61
3842076 1985
44
CT and histological findings of diffuse lipomatosis with a hemangioendothelioma: a case report. 61
3832955 1985
45
Adenolipoma (thyrolipoma) of the thyroid gland report of two cases and review of literature. 61
6433552 1984
46
[Case of diffuse lipomatosis of the neck]. 61
7241980 1981
47
[Diffuse polypoid lipomatosis coli with hypertrophy of the appendices epiploicae in congenital lipomatosis (author's transl)]. 61
7439059 1980
48
Lipomatous lesions of the uterus. 61
150107 1978
49
Different clinical types of lipomatosis. Case report. 61
663569 1978
50
[Diffuse entero-mesenteric lipomatosis]. 61
854206 1977

Variations for Diffuse Lipomatosis

Expression for Diffuse Lipomatosis

Search GEO for disease gene expression data for Diffuse Lipomatosis.

Pathways for Diffuse Lipomatosis

Pathways related to Diffuse Lipomatosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.12 MDM2 CDK4
2 10.82 MDM2 CDK4
3 10.6 MDM2 CDK4
4 10.13 MDM2 CDK4

GO Terms for Diffuse Lipomatosis

Biological processes related to Diffuse Lipomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 9.16 MIRLET7B MDM2
2 positive regulation of cell cycle GO:0045787 8.96 MDM2 CDK4
3 negative regulation of cell cycle arrest GO:0071157 8.62 MDM2 CDK4

Sources for Diffuse Lipomatosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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