MCID: DFF013
MIFTS: 23

Diffuse Meningeal Melanocytosis

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Diffuse Meningeal Melanocytosis

MalaCards integrated aliases for Diffuse Meningeal Melanocytosis:

Name: Diffuse Meningeal Melanocytosis 12 15
Diffuse Melanocytosis 12 73
Diffuse Melanosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6379
NCIt 50 C6890
UMLS 73 C1266112

Summaries for Diffuse Meningeal Melanocytosis

MalaCards based summary : Diffuse Meningeal Melanocytosis, also known as diffuse melanocytosis, is related to vulvar melanoma and malignant spindle cell melanoma, and has symptoms including seizures An important gene associated with Diffuse Meningeal Melanocytosis is ZIC1 (Zic Family Member 1), and among its related pathways/superpathways is Lung fibrosis. Affiliated tissues include brain, skin and kidney, and related phenotype is no phenotypic analysis.

Related Diseases for Diffuse Meningeal Melanocytosis

Diseases related to Diffuse Meningeal Melanocytosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 39)
# Related Disease Score Top Affiliating Genes
1 vulvar melanoma 29.8 MLANA TYR
2 malignant spindle cell melanoma 10.1 PMEL TYR
3 vitiligo-associated multiple autoimmune disease susceptibility 6 10.1 PMEL TYR
4 melanomatosis 10.1 CD68 CWC22
5 hermansky-pudlak syndrome 3 10.1 PMEL TYR
6 gallbladder melanoma 10.1 MLANA PMEL
7 low tension glaucoma 10.1 EDN1 OPTN
8 melanocytic nevus syndrome, congenital 10.1 EDN1 TYR
9 acute kidney tubular necrosis 10.1 HGF TYR
10 vitiligo-associated multiple autoimmune disease susceptibility 1 10.1 PMEL TYR
11 dowling-degos disease 1 10.1 EDN1 TYR
12 pigmented basal cell carcinoma 10.0 MLANA TYR
13 epithelioid cell melanoma 10.0 MLANA TYR
14 breast angiosarcoma 10.0 MLANA TYR
15 balloon cell malignant melanoma 10.0 CD68 MLANA
16 malignant skin fibrous histiocytoma 10.0 MLANA TYR
17 acute kidney failure 10.0 HGF TYR
18 vogt-koyanagi-harada disease 10.0 PMEL TYR
19 brain sarcoma 10.0 CD68 MLANA
20 malignant dermis tumor 10.0 MLANA TYR
21 myxosarcoma 10.0 CD68 MLANA
22 sarcomatoid squamous cell skin carcinoma 10.0 CD68 MLANA
23 optic nerve disease 10.0 EDN1 OPTN TYR
24 limb ischemia 10.0 EDN1 HGF
25 nodular tenosynovitis 9.9 CD68 S100A9
26 halo nevi 9.9 MLANA PMEL TYR
27 adult xanthogranuloma 9.9 CD68 S100A9
28 melanoacanthoma 9.9 MLANA PMEL TYR
29 melanoma, uveal 9.9 MLANA PMEL TYR
30 erythema elevatum diutinum 9.9 CD68 S100A9
31 meningeal melanocytoma 9.9 CD68 CWC22 MLANA
32 reticulohistiocytic granuloma 9.9 CD68 S100A9
33 skin melanoma 9.9 PMEL TYR
34 melanoma 9.9
35 obstructive jaundice 9.9 EDN1 HGF
36 congenital epulis 9.9 CD68 S100A9
37 xanthogranulomatous cholecystitis 9.9 CD68 S100A9
38 microphthalmia 9.8 MLANA PMEL TYR
39 central nervous system melanocytic neoplasm 8.9 CD68 CWC22 HGF MLANA OPTN PMEL

Graphical network of the top 20 diseases related to Diffuse Meningeal Melanocytosis:



Diseases related to Diffuse Meningeal Melanocytosis

Symptoms & Phenotypes for Diffuse Meningeal Melanocytosis

UMLS symptoms related to Diffuse Meningeal Melanocytosis:


seizures

MGI Mouse Phenotypes related to Diffuse Meningeal Melanocytosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 9.1 CD68 HGF MLANA OPTN PMEL TYR

Drugs & Therapeutics for Diffuse Meningeal Melanocytosis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Identification of Compound Isolated From Cock's Comb and Its Effect on Arsenical Palmar Keratosis Recruiting NCT03635853 Phase 2 drug containing extract from cock's comb

Search NIH Clinical Center for Diffuse Meningeal Melanocytosis

Genetic Tests for Diffuse Meningeal Melanocytosis

Anatomical Context for Diffuse Meningeal Melanocytosis

MalaCards organs/tissues related to Diffuse Meningeal Melanocytosis:

41
Brain, Skin, Kidney, Breast

Publications for Diffuse Meningeal Melanocytosis

Articles related to Diffuse Meningeal Melanocytosis:

# Title Authors Year
1
Black brain: transformation of a melanocytoma with diffuse melanocytosis into a primary cerebral melanoma. ( 20640479 )
2011

Variations for Diffuse Meningeal Melanocytosis

Expression for Diffuse Meningeal Melanocytosis

Search GEO for disease gene expression data for Diffuse Meningeal Melanocytosis.

Pathways for Diffuse Meningeal Melanocytosis

Pathways related to Diffuse Meningeal Melanocytosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.42 EDN1 HGF

GO Terms for Diffuse Meningeal Melanocytosis

Cellular components related to Diffuse Meningeal Melanocytosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 melanosome GO:0042470 8.8 MLANA PMEL TYR

Biological processes related to Diffuse Meningeal Melanocytosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 melanin biosynthetic process GO:0042438 8.62 PMEL TYR

Sources for Diffuse Meningeal Melanocytosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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