MCID: DGS008
MIFTS: 13

Digestive System Melanoma

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases, Rare diseases, Skin diseases

Aliases & Classifications for Digestive System Melanoma

MalaCards integrated aliases for Digestive System Melanoma:

Name: Digestive System Melanoma 52 71
Malignant Melanoma of the Gastrointestinal Tract 52
Melanoma of the Gastrointestinal Tract 52
Primary Gastrointestinal Melanoma 52
Melanoma of the Gi Tract 52

Classifications:



External Ids:

UMLS 71 C1333798

Summaries for Digestive System Melanoma

NIH Rare Diseases : 52 Digestive system melanoma refers to a melanoma starting in the stomach, intestines, salivary glands, mouth, esophagus, liver, pancreas, gallbladder, or rectum. Melanoma is a disease in which malignant (cancer ) cells form in the melanocytes. Melanocytes are commonly found in the skin and are the cells that give the skin color. While it is not uncommon for melanomas to start in the skin and later spread to other parts of the body (metastasize ), melanomas originating in the gastrointestinal tract are rare. The most frequently reported site is in the esophagus and anorectum. Symptoms of a digestive system melanoma may be nonspecific, including blood in the stool , stomach pain, vomiting, diarrhea, weight loss and anemia (low red blood cell count). The cause of digestive system melanoma is not well understood. Some researchers theorize that it may have originated from an undetected primary tumor . Treatment may include surgical excision of the gastrointestinal tract involved, chemotherapy , and immunotherapy .

MalaCards based summary : Digestive System Melanoma, also known as malignant melanoma of the gastrointestinal tract, is related to melanoma, cutaneous malignant 10 and melanoma. Affiliated tissues include liver, pancreas and salivary gland.

Related Diseases for Digestive System Melanoma

Diseases related to Digestive System Melanoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 melanoma, cutaneous malignant 10 10.3
2 melanoma 10.3
3 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.0
4 mucosal melanoma 10.0
5 gastric ulcer 10.0
6 ocular melanoma 10.0
7 superficial spreading melanoma 10.0
8 dysphagia 10.0
9 active peptic ulcer disease 10.0
10 intussusception 9.9

Graphical network of the top 20 diseases related to Digestive System Melanoma:



Diseases related to Digestive System Melanoma

Symptoms & Phenotypes for Digestive System Melanoma

Drugs & Therapeutics for Digestive System Melanoma

Search Clinical Trials , NIH Clinical Center for Digestive System Melanoma

Genetic Tests for Digestive System Melanoma

Anatomical Context for Digestive System Melanoma

MalaCards organs/tissues related to Digestive System Melanoma:

40
Liver, Pancreas, Salivary Gland, Skin, Colon

Publications for Digestive System Melanoma

Articles related to Digestive System Melanoma:

# Title Authors PMID Year
1
A Case of Primary Melanoma of the Transverse Colon. 61
29308331 2017
2
Melanoma of stomach. 61
22125087 2012

Variations for Digestive System Melanoma

Expression for Digestive System Melanoma

Search GEO for disease gene expression data for Digestive System Melanoma.

Pathways for Digestive System Melanoma

GO Terms for Digestive System Melanoma

Sources for Digestive System Melanoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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