MCID: DPT001
MIFTS: 15

Dipetalonemiasis

Categories: Infectious diseases

Aliases & Classifications for Dipetalonemiasis

MalaCards integrated aliases for Dipetalonemiasis:

Name: Dipetalonemiasis 12 15
Dipetalonema Infections 44 73
Infection by Dipetalonema Perstans 12
Dipetalonema Infectious Disease 12
Infection by Dipetalonema 12

Classifications:



External Ids:

Disease Ontology 12 DOID:14422
ICD9CM 35 125.4
MeSH 44 D004154
NCIt 50 C34540
UMLS 73 C0012517

Summaries for Dipetalonemiasis

Disease Ontology : 12 A filariasis that is a zoonotic infection caused by the nematode of the genus Dipetalonema, which is transmitted accidentally to humans from porcupines, beavers and other mammals by mosquitoes. The adult worms live subcutaneously or in body cavities or in the eyes of humans. Dead worms cause hypersensitivity necrosis with eosinophils, followed by granulomatous reaction and fibrosis.

MalaCards based summary : Dipetalonemiasis, also known as dipetalonema infections, is related to acanthocheilonemiasis. An important gene associated with Dipetalonemiasis is ALB (Albumin). The drugs Praziquantel and Anthelmintics have been mentioned in the context of this disorder. Affiliated tissues include eye.

Related Diseases for Dipetalonemiasis

Diseases related to Dipetalonemiasis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 acanthocheilonemiasis 10.9

Symptoms & Phenotypes for Dipetalonemiasis

Drugs & Therapeutics for Dipetalonemiasis

Drugs for Dipetalonemiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Praziquantel Approved, Investigational, Vet_approved Phase 4 55268-74-1 4891
2 Anthelmintics Phase 4,Not Applicable
3 Anti-Infective Agents Phase 4,Phase 2,Not Applicable
4 Antiparasitic Agents Phase 4,Phase 2,Not Applicable
5
Doxycycline Approved, Investigational, Vet_approved Phase 2 564-25-0 54671203
6 Anti-Bacterial Agents Phase 2
7 Antimalarials Phase 2
8 Antiprotozoal Agents Phase 2,Not Applicable
9
Albendazole Approved, Vet_approved Not Applicable 54965-21-8 2082
10
Ivermectin Approved, Investigational, Vet_approved Not Applicable 70288-86-7 6474909
11
Diethylcarbamazine Approved, Investigational, Vet_approved 90-89-1 3052
12
Suramin Approved, Investigational 145-63-1 5361
13 Antimitotic Agents Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquantel in People With Schistosomiasis Not yet recruiting NCT02734186 Phase 4 Praziquantel
2 Concomitant Infections of Mansonella Perstans in Tuberculosis and Buruli Ulcer Disease Patients From Ghana Completed NCT02281643 Phase 2 Doxycycline
3 Doxycycline to Treat Mansonella Perstans Infection in Patients With and Without Lymphatic Filariasis Completed NCT00340691 Phase 2 Doxycycline
4 Epidemiology and Control of Mansonella Perstans Infection in Uganda Completed NCT00215280 Not Applicable ivermectin and albendazole
5 Host Response to Infection and Treatment in Filarial Diseases Recruiting NCT00001230

Search NIH Clinical Center for Dipetalonemiasis

Cochrane evidence based reviews: dipetalonema infections

Genetic Tests for Dipetalonemiasis

Anatomical Context for Dipetalonemiasis

MalaCards organs/tissues related to Dipetalonemiasis:

41
Eye

Publications for Dipetalonemiasis

Variations for Dipetalonemiasis

Expression for Dipetalonemiasis

Search GEO for disease gene expression data for Dipetalonemiasis.

Pathways for Dipetalonemiasis

GO Terms for Dipetalonemiasis

Sources for Dipetalonemiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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