MCID: DPH003
MIFTS: 31

Diphyllobothriasis

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Diphyllobothriasis

MalaCards integrated aliases for Diphyllobothriasis:

Name: Diphyllobothriasis 12 59 3 44 15 73
Infection by Bothriocephalus 73
Diphyllobothrium Infection 12
Bothriocephalosis 59
Fish Tapeworm 12

Characteristics:

Orphanet epidemiological data:

59
diphyllobothriasis
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy;

Classifications:

Orphanet: 59  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:10075
ICD10 33 B70.0
ICD9CM 35 123.4
MeSH 44 D004169
NCIt 50 C128391
SNOMED-CT 68 49047003
Orphanet 59 ORPHA128
UMLS via Orphanet 74 C0012561 C0277032
ICD10 via Orphanet 34 B70.0

Summaries for Diphyllobothriasis

CDC : 3 Diphyllobothrium latum and related species (the fish or broad tapeworm), the largest tapeworms that can infect people, can grow up to 30 feet long. While most infections are asymptomatic, complications include intestinal obstruction and gall bladder disease caused by migration of proglottids. Diagnosis is made by identification of eggs or segments of the tapeworm in a stool sample with a microscope. Safe and effective medications are available to treat Diphyllobothrium. Infections are acquired by eating raw or undercooked fish, usually from the Northern Hemisphere (Europe, newly independent states of the Former Soviet Union, North America, Asia), but cases have also been reported in Uganda and Chile. Fish infected with Diphyllobothrium larvae may be transported to and consumed in any area of the world. Adequately freezing or cooking fish will kill the parasite.

MalaCards based summary : Diphyllobothriasis, also known as infection by bothriocephalus, is related to sparganosis and pernicious anemia. An important gene associated with Diphyllobothriasis is MT-TS2 (Mitochondrially Encoded TRNA Serine 2 (AGU/C)), and among its related pathways/superpathways is Gastric acid production. Affiliated tissues include pancreas.

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves parasitic infection caused by Diphyllobothrium latum through the consumption of raw or undercooked fish. The symptoms include abdominal discomfort, diarrhea, vomiting, weight loss and vitamin B12 deficiency with pernicious anemia.

Wikipedia : 76 Diphyllobothriasis is the infection caused by tapeworms of the Diphyllobothrium genus, commonly... more...

Related Diseases for Diphyllobothriasis

Diseases related to Diphyllobothriasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
# Related Disease Score Top Affiliating Genes
1 sparganosis 30.5 MT-ND3 MT-CO1
2 pernicious anemia 30.1 GAST CBLIF
3 bothriocephalosis 11.3
4 vitamin b12 deficiency 10.3
5 sideroblastic anemia acquired 10.3 MT-CO1 MT-ATP8
6 striatonigral degeneration, infantile 10.2 MT-ND3 MT-ATP8
7 striatonigral degeneration, infantile, mitochondrial 10.2 MT-ND3 MT-ATP8
8 myiasis 10.2 MT-ND5 MT-CO1
9 myopathy, lactic acidosis, and sideroblastic anemia 10.2 MT-ND3 MT-ATP8
10 myopathy, lactic acidosis, and sideroblastic anemia 3 10.2 MT-ND3 MT-ATP8
11 cardiomyopathy, infantile hypertrophic 10.2 MT-ND3 MT-ATP8
12 ataxia and polyneuropathy, adult-onset 10.2 MT-ND3 MT-ATP8
13 cercarial dermatitis 10.2 MT-CO1 MT-ATP8
14 mitochondrial dna depletion syndrome 1 10.2 MT-ND3 MT-ATP8
15 ancylostomiasis 10.1 SERPINA1 MT-CO1
16 deafness, nonsyndromic sensorineural, mitochondrial 10.1 MT-ND5 MT-CO1 MT-ATP8
17 myoclonic epilepsy associated with ragged-red fibers 10.1 MT-TS2 MT-TL1 MT-ND5
18 retinitis pigmentosa 40 10.1 MT-CO1 GAST
19 mitochondrial metabolism disease 10.1 MT-TL1 MT-ND5 MT-ND3
20 leber hereditary optic neuropathy 10.1 MT-ND5 MT-ND3 MT-CO1
21 insulinomatosis and diabetes mellitus 10.1 SCT GAST
22 diarrhea 10.1
23 anisakiasis 10.1
24 vipoma 10.1 SCT GAST
25 duodenogastric reflux 10.1 SCT GAST
26 gastrointestinal neuroendocrine benign tumor 10.1 GAST CBLIF
27 holoprosencephaly 1 10.1 SERPINA1 MT-CO1
28 granulomatous gastritis 10.1 GAST CBLIF
29 gastric neuroendocrine neoplasm 10.1 GAST CBLIF
30 pancreatic cholera 10.1 SCT GAST
31 pancreatic steatorrhea 10.1 SCT CBLIF
32 leber optic atrophy 10.1 MT-ND5 MT-ND3 MT-CO1 MT-ATP8
33 familial colorectal cancer 10.1 MT-ND5 MT-ND3 MT-CO1 MT-ATP8
34 duodenal gastrinoma 10.0 SCT GAST
35 mitochondrial encephalomyopathy 10.0 MT-TL1 MT-ND5 MT-ND3 MT-CO1
36 mitochondrial myopathy 10.0 MT-TL1 MT-ND5 MT-CO1 MT-ATP8
37 kearns-sayre syndrome 10.0 MT-TL1 MT-ND5 MT-CO1 MT-ATP8
38 gastrinoma 10.0 SCT GAST
39 blind loop syndrome 10.0 SERPINA1 CBLIF
40 optic nerve disease 10.0
41 neuropathy 10.0
42 xp22.3 microdeletion syndrome 10.0
43 zollinger-ellison syndrome 10.0 SCT GAST
44 mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes 10.0 MT-TS2 MT-TL1 MT-ND5 MT-ND3 MT-CO1
45 space motion sickness 10.0 SCT GAST
46 gastrointestinal system disease 9.9 SERPINA1 SCT GAST
47 leigh syndrome 9.9 MT-TL1 MT-ND5 MT-ND3 MT-CO1 MT-ATP8
48 autoimmune disease of gastrointestinal tract 9.9 GAST CBLIF
49 peptic ulcer disease 9.8 SCT GAST

Graphical network of the top 20 diseases related to Diphyllobothriasis:



Diseases related to Diphyllobothriasis

Symptoms & Phenotypes for Diphyllobothriasis

Drugs & Therapeutics for Diphyllobothriasis

Search Clinical Trials , NIH Clinical Center for Diphyllobothriasis

Cochrane evidence based reviews: diphyllobothriasis

Genetic Tests for Diphyllobothriasis

Anatomical Context for Diphyllobothriasis

MalaCards organs/tissues related to Diphyllobothriasis:

41
Pancreas

Publications for Diphyllobothriasis

Articles related to Diphyllobothriasis:

(show all 50)
# Title Authors Year
1
Diphyllobothriasis in a U.S. Military Aviator. ( 29673434 )
2018
2
Epidemiology of Diphyllobothrium nihonkaiense Diphyllobothriasis, Japan, 2001-2016. ( 30016246 )
2018
3
Intermittent obstructive symptoms in a patient withA diphyllobothriasis. ( 28602516 )
2017
4
Molecular diagnosis of diphyllobothriasis in Spain, most presumably acquired via imported fish, or sojourn abroad. ( 25356331 )
2014
5
Imported diphyllobothriasis in Switzerland: molecular methods to define a clinical case of Diphyllobothrium infection as Diphyllobothrium dendriticum, August 2010. ( 23351654 )
2013
6
Diphyllobothriasis in a nine-year-old child in India: a case report. ( 21801350 )
2011
7
Molecular identification of the Diphyllobothrium species causing diphyllobothriasis in Chilean patients. ( 20165877 )
2010
8
Possible influence of the ENSO phenomenon on the pathoecology of diphyllobothriasis and anisakiasis in ancient Chinchorro populations. ( 20209332 )
2010
9
Diphyllobothriasis, a rare cause of profuse diarrhea following autologous transplantation. ( 19169286 )
2009
10
Diphyllobothriasis associated with eating raw pacific salmon. ( 19523283 )
2009
11
Diphyllobothriasis. ( 19687603 )
2009
12
Imported diphyllobothriasis in Switzerland: molecular evidence of Diphyllobothrium dendriticum (Nitsch, 1824). ( 17805571 )
2008
13
Diphyllobothriasis nihonkaiense: possibly acquired in Switzerland from imported Pacific salmon. ( 18628587 )
2008
14
Education and imaging. Gastrointestinal: diphyllobothriasis. ( 17295781 )
2007
15
A case of Diphyllobothrium latum infection with a brief review of diphyllobothriasis in the Republic of Korea. ( 17876168 )
2007
16
A rare case of diphyllobothriasis from Pondicherry, South India. ( 17582189 )
2007
17
A case of human diphyllobothriasis in northern Taiwan after eating raw fish fillets. ( 17932608 )
2007
18
A woman who excreted a tape-like substance. Diphyllobothriasis. ( 16425463 )
2006
19
A second case of diphyllobothriasis in Malaysia. ( 17333730 )
2006
20
Diphyllobothriasis in Saudi Arabia. ( 17143373 )
2006
21
Diphyllobothriasis latum: the first child case report in Taiwan. ( 16849103 )
2006
22
Human diphyllobothriasis: reports from Rio de Janeiro, Brazil. ( 16153350 )
2005
23
Diphyllobothriasis, Brazil. ( 16318703 )
2005
24
Current situation of human diphyllobothriasis in Europe. ( 15208471 )
2004
25
Current situation of human diphyllobothriasis in Europe. ( 29183498 )
2004
26
Diphyllobothriasis. ( 12505031 )
2003
27
Diagnosing ancient diphyllobothriasis from Chinchorro mummies. ( 12687781 )
2003
28
Diphyllobothriasis: the first case report from Malaysia. ( 12236417 )
2002
29
Diphyllobothriasis: update on human cases, foci, patterns and sources of human infections and future considerations. ( 12041607 )
2001
30
Reappearance of human diphyllobothriasis in a limited area of Lake Como, Italy. ( 11339482 )
2001
31
New cases of human diphyllobothriasis in Patagonia, Argentina. ( 11359210 )
2001
32
Human diphyllobothriasis: first report from India. ( 9764326 )
1998
33
Diphyllobothriasis after eating raw salmon. ( 9264206 )
1997
34
Diphyllobothriasis: fish tapeworm disease in the circumpolar north. ( 2021393 )
1991
35
A case of diphyllobothriasis due to eating masou-sushi. ( 3736454 )
1986
36
Fish tapeworm infections (diphyllobothriasis) in Canada, particularly British Columbia. ( 6713334 )
1984
37
Diphyllobothriasis associated with salmon consumption in Pacific Coast states. ( 6731678 )
1984
38
Gefilte fish does not transmit diphyllobothriasis. ( 6848822 )
1983
39
Gefilte fish and diphyllobothriasis. ( 7062455 )
1982
40
Prevalence of diphyllobothriasis. ( 7062456 )
1982
41
Diphyllobothriasis in Americans and Asians. ( 7069870 )
1982
42
Diphyllobothriasis. ( 7299975 )
1981
43
Diphyllobothriasis. ( 474363 )
1979
44
Human diphyllobothriasis in Peru. ( 5628217 )
1967
45
Diphyllobothriasis in Finland, with special reference to incidence, transmission and clinical features. ( 14440508 )
1960
46
Dichlorophen in the treatment of diphyllobothriasis. ( 13783172 )
1960
47
Diphyllobothriasis as an infectious disease in Finland. ( 14413480 )
1959
48
The recognition and present treatment of endemic fish tapeworm infestation (diphyllobothriasis). ( 14398677 )
1955
49
Diphyllobothriasis (fish tapeworm infestation); a case report and review of current concepts. ( 13257251 )
1955
50
Indian and Eskimo diphyllobothriasis. ( 13160882 )
1954

Variations for Diphyllobothriasis

Expression for Diphyllobothriasis

Search GEO for disease gene expression data for Diphyllobothriasis.

Pathways for Diphyllobothriasis

Pathways related to Diphyllobothriasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.64 CBLIF GAST SCT

GO Terms for Diphyllobothriasis

Cellular components related to Diphyllobothriasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial inner membrane GO:0005743 9.26 MT-ATP8 MT-CO1 MT-ND3 MT-ND5
2 respiratory chain GO:0070469 8.8 MT-CO1 MT-ND3 MT-ND5

Biological processes related to Diphyllobothriasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial electron transport, NADH to ubiquinone GO:0006120 8.62 MT-ND3 MT-ND5

Molecular functions related to Diphyllobothriasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NADH dehydrogenase (ubiquinone) activity GO:0008137 8.62 MT-ND3 MT-ND5

Sources for Diphyllobothriasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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