MCID: DPH003
MIFTS: 33

Diphyllobothriasis

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Diphyllobothriasis

MalaCards integrated aliases for Diphyllobothriasis:

Name: Diphyllobothriasis 12 58 3 44 15 17 70 32
Diphyllobothrium Infection 12 3
Infection by Bothriocephalus 70
Bothriocephalosis 58
Fish Tapeworm 12

Characteristics:

Orphanet epidemiological data:

58
diphyllobothriasis
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy;

Classifications:

Orphanet: 58  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:10075
ICD9CM 34 123.4
MeSH 44 D004169
NCIt 50 C128391
SNOMED-CT 67 187151009
ICD10 32 B70.0
ICD10 via Orphanet 33 B70.0
UMLS via Orphanet 71 C0012561 C0277032
Orphanet 58 ORPHA128
UMLS 70 C0012561 C0277032

Summaries for Diphyllobothriasis

CDC : 3 Diphyllobothrium latum and related species (the fish or broad tapeworm), the largest tapeworms that can infect people, can grow up to 30 feet long. While most infections are asymptomatic, complications include intestinal obstruction and gall bladder disease caused by migration of proglottids. Diagnosis is made by identification of eggs or segments of the tapeworm in a stool sample with a microscope. Safe and effective medications are available to treat Diphyllobothrium. Infections are acquired by eating raw or undercooked fish, usually from the Northern Hemisphere (Europe, newly independent states of the Former Soviet Union, North America, Asia), but cases have also been reported in Uganda and Chile. Fish infected with Diphyllobothrium larvae may be transported to and consumed in any area of the world. Adequately freezing or cooking fish will kill the parasite.

MalaCards based summary : Diphyllobothriasis, also known as diphyllobothrium infection, is related to vitamin b12 deficiency and taeniasis. An important gene associated with Diphyllobothriasis is MT-CO1 (Mitochondrially Encoded Cytochrome C Oxidase I), and among its related pathways/superpathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Prion disease. Affiliated tissues include small intestine.

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves parasitic infection caused by Diphyllobothrium latum through the consumption of raw or undercooked fish. The symptoms include abdominal discomfort, diarrhea, vomiting, weight loss and vitamin B12 deficiency with pernicious anemia.

Wikipedia : 73 Diphyllobothriasis is the infection caused by tapeworms of the genus Diphyllobothrium (commonly D. latum... more...

Related Diseases for Diphyllobothriasis

Diseases related to Diphyllobothriasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 76)
# Related Disease Score Top Affiliating Genes
1 vitamin b12 deficiency 29.9 CBLIF AMN
2 taeniasis 29.8 MT-ND1 MT-CO1
3 sparganosis 29.7 MT-ND3 MT-ND1 MT-CO1
4 parasitic helminthiasis infectious disease 29.6 MT-ND1 MT-CO1
5 neuropathy 29.4 MT-ND5 MT-ND3 MT-ND1 MT-CO1
6 optic nerve disease 29.3 MT-ND5 MT-ND3 MT-ND1 MT-CO1
7 bothriocephalosis 11.1
8 papillomatosis, confluent and reticulated 10.4
9 opisthorchiasis 10.3
10 gnathomiasis 10.2 MT-TS2 MT-CO1
11 polycystic echinococcosis 10.0 MT-ND1 MT-CO1
12 cystic echinococcosis 10.0 MT-ND1 MT-CO1
13 echinococcosis 10.0 MT-ND1 MT-CO1
14 myiasis 10.0 MT-ND1 MT-CO1
15 disease by infectious agent 10.0
16 dumping syndrome 10.0
17 tropical sprue 10.0 CBLIF AMN
18 congenital intrinsic factor deficiency 10.0 CBLIF AMN
19 deafness, nonsyndromic sensorineural, mitochondrial 10.0 MT-ND1 MT-CO1
20 hereditary optic neuropathy 10.0 MT-ND5 MT-ND1
21 leber optic atrophy and dystonia 10.0 MT-ND3 MT-ND1
22 vitamin metabolic disorder 10.0 CBLIF AMN
23 cysticercosis 10.0 MT-ND1 MT-CO1
24 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.0
25 deficiency anemia 10.0
26 kidney disease 10.0
27 peptic ulcer disease 10.0
28 hypereosinophilic syndrome 10.0
29 fascioliasis 10.0 MT-ND1 MT-CO1
30 severe congenital neutropenia 1 9.9 MT-ND5 MT-ND1
31 deafness, aminoglycoside-induced 9.9 MT-ND1 MT-CO1
32 mitochondrial metabolism disease 9.9 MT-ND3 MT-ND1
33 pernicious anemia 9.9
34 diffuse large b-cell lymphoma 9.9
35 lymphoma 9.9
36 hymenolepiasis 9.9
37 diarrhea 9.9
38 gastritis 9.9
39 anisakiasis 9.9
40 b-cell lymphoma 9.9
41 metagonimiasis 9.9
42 distomatosis 9.9
43 coenurosis 9.8 MT-TS2 MT-ND1 MT-CO1
44 megaloblastic anemia 9.8 MT-CO1 CBLIF AMN
45 3-methylglutaconic aciduria 9.8 MT-TL1 AMN
46 cortical blindness 9.8 MT-ND5 MT-ND1
47 baylisascariasis 9.8 MT-ND5 MT-ND1 MT-CO1
48 mitochondrial myopathy, infantile, transient 9.8 MT-ND5 MT-ND1 MT-CO1
49 pthirus pubis infestation 9.8 MT-ND5 MT-ND1 MT-CO1
50 lice infestation 9.8 MT-ND5 MT-ND1 MT-CO1

Graphical network of the top 20 diseases related to Diphyllobothriasis:



Diseases related to Diphyllobothriasis

Symptoms & Phenotypes for Diphyllobothriasis

Drugs & Therapeutics for Diphyllobothriasis

Search Clinical Trials , NIH Clinical Center for Diphyllobothriasis

Cochrane evidence based reviews: diphyllobothriasis

Genetic Tests for Diphyllobothriasis

Anatomical Context for Diphyllobothriasis

MalaCards organs/tissues related to Diphyllobothriasis:

40
Small Intestine

Publications for Diphyllobothriasis

Articles related to Diphyllobothriasis:

(show top 50) (show all 270)
# Title Authors PMID Year
1
A Case of Refractory Diphyllobothriasis in a Young Pediatric Patient. 61
31972005 2021
2
Raw fish and diphyllobothriasis infection. 61
31926009 2020
3
Human diphyllobothriasis - Authors' reply. 61
32919508 2020
4
Human diphyllobothriasis. 61
32919507 2020
5
Occurrence and Spatial Distribution of Dibothriocephalus Latus (Cestoda: Diphyllobothriidea) in Lake Iseo (Northern Italy): An Update. 61
32674519 2020
6
The Things They Carry: Diphyllobothriasis at Sea, a Case Report. 61
32134460 2020
7
Locally acquired infection with Dibothriocephalus nihonkaiense (=Diphyllobothrium nihonkaiense) in France: the importance of molecular diagnosis. 61
31848744 2020
8
[Persistent malnutrition caused by Nihonkaiense diphyllobothriasis diagnosed during treatment of malignant lymphoma]. 61
32759561 2020
9
Endohelminths of European Perch (Perca fluviatilis) from Selected Localities in Poland with an Emphasis on Search of the Broad Fish Tapeworm Dibothriocephalus latus. 61
31165987 2019
10
Epidemiology of Diphyllobothrium nihonkaiense Diphyllobothriasis, Japan, 2001-2016. 61
30016246 2018
11
Diphyllobothriasis in a U.S. Military Aviator. 61
29673434 2018
12
Intermittent obstructive symptoms in a patient with diphyllobothriasis. 61
28602516 2017
13
A case of Diphyllobothrium latum infection in Dalian and a brief review of diphyllobothriasis in China. 61
33592940 2017
14
Molecular Identification of Diphyllobothrium latum from a Pediatric Case in Taiwan. 61
28877575 2017
15
Four Human Cases of Diphyllobothrium nihonkaiense (Eucestoda: Diphyllobothriidae) in China with a Brief Review of Chinese Cases. 61
28719957 2017
16
[(THE CURRENT SITUATION OF DIPHYLLOBOTHRIASIS: EPIDEMIOLOGY AND EPIDEMIOLOGICAL SURVEILLANCE)]. 61
30721617 2017
17
Traditional Living Habits of the Taz Tundra Population: A Paleoparasitological Study. 61
27853118 2016
18
Prevalence of Diphyllobothrium latum (Cestoda: Diphyllobothriidae) plerocercoids in fish species from four Italian lakes and risk for the consumers. 61
27491055 2016
19
Molecular Identification of Diphyllobothrium nihonkaiense from 3 Human Cases in Heilongjiang Province with a Brief Literature Review in China. 61
26797434 2015
20
Diphyllobothrium sp. in Canis familiaris from the subtropical area of Argentina (Puerto Iguazú, Misiones). 61
26210607 2015
21
Three cases of Diphyllobothrium nihonkaiense infection in Korea. 61
25548420 2014
22
Two human cases of Diphyllobothrium nihonkaiense infection in Korea. 61
24850965 2014
23
Parasitic infections based on 320 clinical samples submitted to Hanyang University, Korea (2004-2011). 61
24850969 2014
24
Molecular diagnosis of diphyllobothriasis in Spain, most presumably acquired via imported fish, or sojourn abroad. 61
25356331 2014
25
Praziquantel treatment in trematode and cestode infections: an update. 61
24265948 2013
26
Food and water security issues in Russia III: food- and waterborne diseases in the Russian Arctic, Siberia and the Far East, 2000-2011. 61
24350064 2013
27
Imported diphyllobothriasis in Switzerland: molecular methods to define a clinical case of Diphyllobothrium infection as Diphyllobothrium dendriticum, August 2010. 61
23351654 2013
28
[The environmental conditions and predictors of formation of the bases for a combination of Diphyllobothrium dendriticum and Triaenophorus nodulosus foci in the flood-river ecosystem of the Angara River]. 61
22774497 2012
29
[The specific features of Diphyllobothrium latum circulation in the natural foci of the Kostroma region]. 61
22536738 2012
30
Diphyllobothriasis in a nine-year-old child in India: a case report. 61
21801350 2011
31
[Approaches to developing a procedure for mapping water basin regions, by using the parasitological criteria]. 61
21932540 2011
32
Case of sparganosis: a diagnostic dilemma. 61
21654118 2011
33
Cytogenetics and chromosomes of tapeworms (Platyhelminthes, Cestoda). 61
21295678 2011
34
Detection and identification of Diphyllobothrium nihonkaiense plerocercoids from wild Pacific salmon (Oncorhynchus spp.) in Japan. 61
20334715 2010
35
Capsule endoscopy is a feasible procedure for identifying a Diphyllobothrium nihonkaiense infection and determining the indications for vermifuge treatment. 61
22767523 2010
36
The DL1 repeats in the genome of Diphyllobothrium latum. 61
20440623 2010
37
Molecular identification of the Diphyllobothrium species causing diphyllobothriasis in Chilean patients. 61
20165877 2010
38
Possible influence of the ENSO phenomenon on the pathoecology of diphyllobothriasis and anisakiasis in ancient Chinchorro populations. 61
20209332 2010
39
A case of Diphyllobothrium nihonkaiense infection possibly linked to salmon consumption in New Zealand. 61
19444469 2009
40
Diphyllobothriasis, a rare cause of profuse diarrhea following autologous transplantation. 61
19169286 2009
41
Diphyllobothriasis associated with eating raw pacific salmon. 61
19523283 2009
42
Evaluation of an enzyme-linked immunoelectrotransfer blot test for the confirmatory serodiagnosis of human toxocariasis. 61
19547865 2009
43
Mitochondrial DNA divergence in populations of the tapeworm Diphyllobothrium nihonkaiense and its phylogenetic relationship with Diphyllobothrium klebanovskii. 61
18835460 2009
44
Diphyllobothriasis. 61
19687603 2009
45
Use of nuclear and mitochondrial DNA PCR and sequencing for molecular identification of Diphyllobothrium isolates potentially infective for humans. 61
18814714 2008
46
Diphyllobothrium latum infection in a non-endemic country: case report. 61
18719813 2008
47
[Characteristics of the focus of diphyllobothriasis on the Votkino reservoir]. 61
18561406 2008
48
Diphyllobothriasis nihonkaiense: possibly acquired in Switzerland from imported Pacific salmon. 61
18628587 2008
49
Imported diphyllobothriasis in Switzerland: molecular evidence of Diphyllobothrium dendriticum (Nitsch, 1824). 61
17805571 2008
50
[A case of Diphyllobothrium latum infection in a patient with abdominal pain]. 61
18159176 2007

Variations for Diphyllobothriasis

Expression for Diphyllobothriasis

Search GEO for disease gene expression data for Diphyllobothriasis.

Pathways for Diphyllobothriasis

Pathways related to Diphyllobothriasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.8 MT-ND5 MT-ND3 MT-ND1 MT-CO1
2
Show member pathways
11.97 MT-ND5 MT-ND3 MT-ND1 MT-CO1
3
Show member pathways
11.95 MT-ND5 MT-ND3 MT-ND1
4
Show member pathways
11.29 CBLIF AMN
5 10.48 CBLIF AMN
6
Show member pathways
9.47 CBLIF AMN

GO Terms for Diphyllobothriasis

Cellular components related to Diphyllobothriasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial inner membrane GO:0005743 9.46 MT-ND5 MT-ND3 MT-ND1 MT-CO1
2 mitochondrial respiratory chain complex I GO:0005747 9.13 MT-ND5 MT-ND3 MT-ND1
3 respiratory chain GO:0070469 8.92 MT-ND5 MT-ND3 MT-ND1 MT-CO1

Biological processes related to Diphyllobothriasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.71 MT-ND5 MT-ND3 MT-ND1 MT-CO1
2 aerobic respiration GO:0009060 9.37 MT-ND1 MT-CO1
3 cobalamin metabolic process GO:0009235 9.32 CBLIF AMN
4 cobalamin transport GO:0015889 9.26 CBLIF AMN
5 electron transport coupled proton transport GO:0015990 9.16 MT-ND5 MT-CO1
6 mitochondrial respiratory chain complex I assembly GO:0032981 9.13 MT-ND5 MT-ND3 MT-ND1
7 mitochondrial electron transport, NADH to ubiquinone GO:0006120 8.8 MT-ND5 MT-ND3 MT-ND1

Molecular functions related to Diphyllobothriasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NADH dehydrogenase activity GO:0003954 8.96 MT-ND5 MT-ND1
2 NADH dehydrogenase (ubiquinone) activity GO:0008137 8.8 MT-ND5 MT-ND3 MT-ND1

Sources for Diphyllobothriasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....