MCID: DRF001
MIFTS: 31

Dirofilariasis

Categories: Infectious diseases, Rare diseases, Respiratory diseases, Skin diseases

Aliases & Classifications for Dirofilariasis

MalaCards integrated aliases for Dirofilariasis:

Name: Dirofilariasis 12 54 60 3 45 15 17 74
Dirofilaria Infectious Disease 12
Infection by Dirofilaria 12

Characteristics:

Orphanet epidemiological data:

60
dirofilariasis
Inheritance: Not applicable; Age of onset: All ages;

Classifications:

Orphanet: 60  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:1082
MeSH 45 D004184
SNOMED-CT 69 73328005
ICD10 34 B74.8
MESH via Orphanet 46 D004184
ICD10 via Orphanet 35 B74.8
UMLS via Orphanet 75 C0012602
Orphanet 60 ORPHA166291
UMLS 74 C0012602

Summaries for Dirofilariasis

NIH Rare Diseases : 54 Dirofilariasis refers to infections caused by Dirofilaria roundworms. Although the natural hosts of these roundworms are dogs, wild canids (such as wolves and foxes) and raccoons, humans can be infected with Dirofilaria larvae through mosquito bites. Signs and symptoms of dirofilariasis generally include nodules under the skin or lung granulomas (small nodules formed by an inflammatory reaction) which may be asymptomatic. Some people with dirofilariasis of the lungs may also experience cough, chest pain, fever, wheezing, chills, and pleural effusion (excess fluid between the tissues that line the lungs and the chest cavity). Dirofilariasis is treated with surgical removal of lung granulomas and skin nodules.

MalaCards based summary : Dirofilariasis, also known as dirofilaria infectious disease, is related to pulmonary coin lesion and lung cancer. An important gene associated with Dirofilariasis is UBASH3A (Ubiquitin Associated And SH3 Domain Containing A). Affiliated tissues include lung, skin and breast, and related phenotype is liver/biliary system.

Disease Ontology : 12 A filariasis that is a zoonotic infection caused by nematodes Dirofilaria immitis or Dirofilaria repens, which are transmitted to humans from dogs, cats, wolves and coyotes by infected mosquitoes. The disease manifests as either subcutaneous nodules or pulmonary lesions.

CDC : 3 Most common questions answered...

Wikipedia : 77 Dirofilariasis is an infection by parasites of the genus Dirofilaria. It is transmitted through a... more...

Related Diseases for Dirofilariasis

Diseases related to Dirofilariasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 26)
# Related Disease Score Top Affiliating Genes
1 pulmonary coin lesion 10.2
2 lung cancer 10.2
3 langerhans cell histiocytosis 10.1
4 filariasis 10.1
5 histiocytosis 10.1
6 toxocariasis 10.1
7 breast cancer 9.9
8 pulmonary hypertension 9.9
9 arthritis 9.9
10 congestive heart failure 9.9
11 eosinophilic meningitis 9.9
12 onchocerciasis 9.9
13 scleritis 9.9
14 pneumothorax 9.9
15 arteriosclerosis 9.9
16 transitional cell carcinoma 9.9
17 dermatitis 9.9
18 neurilemmoma 9.9
19 granulomatous dermatitis 9.9
20 scrotum neoplasm 9.9
21 reactive arthritis 9.9
22 fascioliasis 9.9
23 meningitis 9.9
24 rere-related disorders 9.9
25 multiple endocrine neoplasia 9.9
26 posttransplant acute limbic encephalitis 9.9

Graphical network of the top 20 diseases related to Dirofilariasis:



Diseases related to Dirofilariasis

Symptoms & Phenotypes for Dirofilariasis

MGI Mouse Phenotypes related to Dirofilariasis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 liver/biliary system MP:0005370 8.8 NSUN2 STAB2 THEM4

Drugs & Therapeutics for Dirofilariasis

Search Clinical Trials , NIH Clinical Center for Dirofilariasis

Cochrane evidence based reviews: dirofilariasis

Genetic Tests for Dirofilariasis

Anatomical Context for Dirofilariasis

MalaCards organs/tissues related to Dirofilariasis:

42
Lung, Skin, Breast, Heart, Testes, Eye, B Cells

Publications for Dirofilariasis

Articles related to Dirofilariasis:

(show top 50) (show all 435)
# Title Authors Year
1
Epididymal Dirofilariasis in a Child: First Case Report from Bulgaria. ( 30332673 )
2019
2
Subcutaneous dirofilariasis of the eyelid. ( 30705490 )
2019
3
Subcutaneous Dirofilariasis in Female Pubic Region - Case Report. ( 30834008 )
2019
4
Encapsulated living worms due to periorbital dirofilariasis: detection with high-resolution sonography. ( 30859409 )
2019
5
Systematic Review of Lesser Known Parasitoses: Maxillofacial Dirofilariasis. ( 30996536 )
2019
6
A case of human ocular dirofilariasis in a patient with multiple endocrine neoplasia in Northwest Spain. ( 29223316 )
2018
7
Dirofilariasis mimicking an osteoma. ( 29323001 )
2018
8
Conjunctival Dirofilariasis Causing Symptoms for 1 Day. ( 29351119 )
2018
9
The Canary Islands as a model of risk of pulmonary dirofilariasis in a hyperendemic area. ( 29396676 )
2018
10
A rare case of human pulmonary dirofilariasis with nodules mimicking malignancy: approach to diagnosis and treatment. ( 29891007 )
2018
11
There is a worm in my eye! Ocular dirofilariasis. ( 30270664 )
2018
12
Two cases of subcutaneous dirofilariasis in Barcelona, Spain. ( 30280219 )
2018
13
A Case of Subconjunctival Dirofilariasis in Bulgaria. ( 30355824 )
2018
14
Human oral dirofilariasis. ( 30693219 )
2018
15
Human pulmonary dirofilariasis disguising as a lung tumour. ( 30786694 )
2018
16
Seasonal Activity of Adult Mosquitoes (Diptera: Culicidae) in a Focus of Dirofilariasis and West Nile Infection in Northern Iran. ( 30918909 )
2018
17
Human dirofilariasis in the eyelid caused by Dirofilaria repens: An imported case. ( 27544021 )
2017
18
Ocular dirofilariasis by Dirofilaria immitis in a child in Iran: A case report and review of the literature. ( 27815230 )
2017
19
Intradural Dirofilariasis in a Dog with Chronic Cervical Pain. ( 27841685 )
2017
20
Subcutaneous dirofilariasis: a masquerade of a palisaded granulomatous dermatitis. ( 28000235 )
2017
21
Subcutaneous dirofilariasis caused by Dirofilaria (Nochtiella) repens in Sri Lanka: A potential risk of transmitting human dirofilariasis. ( 28491315 )
2017
22
Delayed diagnosis of subcutaneous dirofilariasis following a mosquito bite sustained in Germany. ( 28557282 )
2017
23
An unusual presentation of lacrimal gland dirofilariasis. ( 28724822 )
2017
24
Ocular Dirofilariasis: A Rare case from Mumbai, India. ( 28764165 )
2017
25
Clinical and laboratory features of human dirofilariasis in Russia. ( 28791217 )
2017
26
A case of orbital dirofilariasis in New York. ( 28812912 )
2017
27
Dirofilariasis in a Female Adult Patient in Israel. ( 28971644 )
2017
28
Ocular dirofilariasis: Ophthalmic implication of climate change on vector-borne parasites. ( 29260070 )
2017
29
Human Subconjunctival Dirofilariasis Presenting as the Daytime Photophobia: A Case Report. ( 29308388 )
2017
30
Pulmonary dirofilariasis: A diagnostic pitfall in clinical practice. ( 26526293 )
2016
31
Human Ocular Dirofilariasis in Hong Kong. ( 26636400 )
2016
32
Periocular dirofilariasis: A case series. ( 26819190 )
2016
33
Rare case of epididymal dirofilariasis. ( 26976948 )
2016
34
Subcutaneous filariasis in India--Possible indication of human Dirofilariasis. ( 27004586 )
2016
35
A rare case of human pulmonary dirofilariasis with a growing pulmonary nodule after migrating infiltration shadows, mimicking primary lung carcinoma. ( 27015012 )
2016
36
Ocular dirofilariasis: Series of three cases and review of literature. ( 27080800 )
2016
37
Periorbital Dirofilariasis: A Rare Case from Western India. ( 27134918 )
2016
38
Dirofilariasis Presenting as an Infiltrative Mass in the Right Buccal Space. ( 27305941 )
2016
39
Human pulmonary dirofilariasis masquerading as a mass. ( 27432058 )
2016
40
Subcutaneous and Pulmonary Dirofilariasis with Evidence of Splenic Involvement. ( 27579206 )
2016
41
DIROFILARIASIS: CURRENT ASPECTS OF STUDIES. ( 30387572 )
2016
42
Human subcutaneous dirofilariasis caused by Dirofilaria immitis in a Greek adult. ( 26166816 )
2016
43
Description of five dirofilariasis cases in South Hungary and review epidemiology of this disease for the country. ( 26178869 )
2015
44
Dirofilariasis - an emergent human parasitosis in Romania. ( 26204187 )
2015
45
Subconjunctival dirofilariasis caused by Dirofilaria repens: A case report with short review. ( 26275256 )
2015
46
Subcutaneous human Dirofilariasis in Vidarbha. ( 26275274 )
2015
47
Subcutaneous Infraorbital Dirofilariasis. ( 26288429 )
2015
48
Oral dirofilariasis. ( 26470974 )
2015
49
Human dirofilariasis: A fast emerging zoonosis in India. ( 26470975 )
2015
50
HUMAN SUBCUTANEOUS DIROFILARIASIS - CASE REPORT. ( 26591641 )
2015

Variations for Dirofilariasis

Expression for Dirofilariasis

Search GEO for disease gene expression data for Dirofilariasis.

Pathways for Dirofilariasis

GO Terms for Dirofilariasis

Sources for Dirofilariasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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